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Works Cited
Alzheimer's Association | Home. 19 Mar. 2009. 19 Mar. 2009 <http://www.alz.org/index.asp>.
This source is the website of the Alzheimer’s Association. It is the largest non-profit
Alzheimer’s organization in the world. Throughout the entire website there is lots of
information pertaining to many topics of Alzheimer’s including: causes, diagnosis, treatments,
prevention and care for individuals with Alzheimer’s disease. This website is very useful due to
the fact that it has a wide range of information although it does not go into too much detail on
an any one subject.
"Alzheimer's disease - MayoClinic.com." Mayo Clinic medical information and tools for healthy
living - MayoClinic.com. 17 Jan. 2009. 19 Mar. 2009
<http://www.mayoclinic.com/health/alzheimers-disease/DS00161>.
This website was very similar to the one mentioned above. It more of a source of reference
rather than a place to gather in depth information. Like the previous source it gives
information on treatments, symptoms and prevention.
"Alzheimer's Disease Fact Sheet." National Institute on Aging. 24 Feb. 2009. 19 Mar. 2009
<http://www.nia.nih.gov/Alzheimers/Publications/adfact.htm>.
This source gives a lot of statistics representing the demographics of people with Alzheimer’s
disease. It also goes in depth on some of the causes of Alzheimer’s disease. It proposes that
Alzheimer’s could in fact be traced back to genetic information in your DNA. The article also
recognizes that there are some lifestyle factors such as your diet, physical activity and levels of
cognitive activity that play a role in the progression of the disease. Alzheimer’s disease is also
broken down into three levels of severity, mild, moderate and severe. In the explanation of each
stage it describes the levels of brain activity and how much brain tissue is destroyed.
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Britschgi, Markus, and Tony Wyss-Coray, PhD. "Blood Protein Signature for the Early
Diagnosis of Alzheimer Disease." 8 Dec. 2008. Proquest. 20 Mar. 2009
<http://za2uf4ps7f.search.serialssolutions.com.proxy1.cl.msu.edu/directLink?&atitle=Blo
od%20Protein%20Signature%20for%20the%20Early%20Diagnosis%20of%20Alzheimer
%20Disease&author=Markus%20Britschgi%3B%20Tony%20WyssCoray&issn=00039942&title=Archives%20of%20Neurology&volume=66&issue=2&dat
e=20090201&spage=161&id=doi:&sid=ProQ_ss&genre=article&lang=en>.
This article discusses the new research discovering the relationship between the levels of a
marker protein in your blood and Alzheimer’s disease. The levels of the protein become very
high in Alzheimer’s patients even before it is clinically diagnosed. The article also goes into the
difficulty of diagnosing Alzheimer’s at an early stage and this protein could greatly help doctors.
Cimons, Marlene. "FDA Approves First Alzheimer's Disease Treatment Medication - The Tech."
The Tech. 10 Sept. 1993. MIT. 19 Mar. 2009
<http://tech.mit.edu/V113/N40/fda.40w.html>.
This source was an article in MIT’s student newspaper. It is a fairly old article but it describes
the first FDA approved treatment for Alzheimer’s called Cognex. The drug inhibits the
breakdown of the neurotransmitter Acetylcholine, allowing more of it to be available to brain
cells. Throughout my research this I found that this neurotransmitter was involved in most of
the Alzheimer’s treatments.
Friedrich, M. J. "Alzheimer Researchers Focus Efforts on Early Development and Earlier
Detection." The Journal of the American Medical Association 300 (2008): 2595-597.
This journal article focuses on the fact that even though the symptoms of Alzheimer’s do not
show up until around age 60, the actual changes in the brain start as early as age 40. This article
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reviewing some of the research being done so doctors are able to detect the development of
Alzheimer’s earlier. The goal is that if it can be detected many years before the symptoms start,
the right treatments and medications can be given to the patient in the hope to prevent the
disease.
Hope, Jenny. "New hope for Alzheimer's sufferers after new treatment 'restores memory in
minutes' | Mail Online." Home | Mail Online. 11 Apr. 2008. 19 Mar. 2009
<http://www.dailymail.co.uk/health/article-558849/New-hope-Alzheimers-sufferers-newtreatment-restores-memory-minutes.html>.
This article discussed a controversial new treatment for Alzheimer’s disease. The treatment
involved injecting the drug Enbrel, which is normally used to treat arthritis, into the spinal cord
in the neck area. In minutes some of the patients’ previous memories were restored but only for
a short span of time. This research marked the first time that symptoms of Alzheimer’s disease
could be reversed.
Lash, M.D., Robert W. "Health Trends Can We Prevent Alzheimer’s Disease?" Discovery
Magazine 20 July 2007. 19 Mar. 2009 <http://discovermagazine.com/2007/jul/can-weprevent-alzheimer2019s-disease>.
In this article, Dr. Lash discusses how research in the Alzheimer’s disease field has slowly
shifted from searching for a cure, to disease prevention. He explains many methods that are
currently being tested for prevention of Alzheimer’s disease such as developing a vaccine and
having patients take supplements in an effort to stop the disease.
Mandavilli, Apoorva. "Two Alzheimer’s Drugs Show Promise." Discovery Magazine. Discovery
Magazine. 19 Dec. 2008. 19 Mar. 2009 <http://discovermagazine.com/2009/jan/018>.
This article discusses two new treatments that are providing benefits for Alzheimer’s patients.
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The drugs Rember and Dimebon are showing signs of slowing the rate of brain damage in the
patients. The scientists are still trying to figure out why these medicines are showing
improvement in these patients as there is no real explanation that has been proven.
Rice, Jocelyin. "High-Intensity MRI Could Catch Alzheimer’s, MS." Discovery Magazine Jan.
2008. Discovery Magazine. 9 Jan. 2008. 19 Mar. 2009
<http://discovermagazine.com/2008/jan/high-intensity-mri-could-catch-alzheimer2019sms>.
This article discusses a new MRI machine that has been developed that could possibly help out
in diagnosing such brain disorders like Alzheimer’s disease and multiple sclerosis. The MRI is
equipped with magnets that are twice as powerful than the ones in standard MRI machines. The
more powerful magnets allow for more detailed brain imaging that aids in the diagnosis of those
diseases.
Trimble, Tyghe, and Sherry Baker. "What Does Alzheimer's Look Like in the Brain?" Discovery
Magazine 4 July 2008. 19 Mar. 2009 <http://discovermagazine.com/2008/aug/04-whatdoes-alzheimer.s-look-like-in-your-brain>.
This article takes a closer look at A-beta fibrils and how they are related to Alzheimer’s. The
fibrils are one of the symptoms of Alzheimer’s patients and slowly engulf many of the cells in
the brain. There is no reason why these fibrils cause the brain cells to go dead it is just known
that there is a direct correlation to the fibrils and the disease.