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Southwest Allergy and Asthma Associates Joe Venzor, M.D. 11410 Vista Del Sol, Suite A, El Paso Texas 79936, (915) 592-6269 Immunotherapy Facts What is Immunotherapy? Immunotherapy is the treatment in which we give small amounts of pollens or mold spores that a patient is allergic to which over time desensitizes the immune system and causes an improvement in a person’s allergies or possibly a cure. This is done by injection or by placing drops under the tongue. This is the only treatment available that addresses the cause of allergies and does not just relieve the symptoms. There are now four options for beginning immunotherapy: 1) ALLERGY SHOTS – MOST EFFECTIVE, LONGEST EXPERIENCE Allergy injections are the type of immunotherapy that’s been around the longest since 1910. Allergy shots are the most studied type of immunotherapy. A majority of patients will become desensitized to the allergens contained in the shots and no longer have allergic reactions to those substances. Allergy shots can provide relief from symptoms that continues after treatment is complete. In children, allergy shots help to prevent them from developing new allergies and prevent allergy related asthma later in life. The build-up phase of 5 months involves receiving injections with increasing amounts of the allergens once a week. Benefit begins within a few months often after a few weeks. The maintenance phase begins when the highest dose is reached. Once the maintenance dose is reached, the injections are given once a month for three years. 2) RUSH IMMUNOTHERAPY – QUICKEST, MORE RISK Same as the normal allergy shots with one big difference. The build up phase occurs in a six hour session during one day. The patient then comes in weekly for one month and then begins their maintenance shot program once a month for three years. Advantages: Four months of weekly shots are skipped. Effectiveness is the same as with normal allergy shots. Disadvantages: A small chance of a severe allergic reaction is present. In order to decrease this chance, four different medications will be given to you as a premedication two days before your visit. 3) CLUSTER IMMUNOTHERAPY – QUICKEST, MORE RISK Faster buildup like Rush immunotherapy but the buildups occur over a two hour period for five weeks instead of in one day. Only two medications are given for premedication and the risk of an allergic reaction is much smaller. After the five weekly sessions you will be at the maximal dose and begin the monthly maintenance dosage. Advantages: Three months of weekly shots are skipped. Effectiveness is the same as with normal allergy shots. Lower risk than with Rush immunotherapy. Disadvantages: A small chance of a severe allergic reaction is present. In order to decrease this chance, two different medications will be given to you as a premedication before your two hour shot session. 4) SUBLINGUAL IMMUNOTHERAPY – LEAST EFFECTIVE, MOST CONVIENIENT This is the injection free way to take your immunotherapy in the comfort of your own home. Sublingual immunotherapy is given by placing drops which contain the allergens you are allergic to under your tongue and swallowed on a daily basis. Duration – 3 years. Advantages: No needles, done at home, and perfect for young children with the advantage of decreasing future allergies and asthma without the trauma of injections. Disadvantages: Not as effective as allergy shots. Health insurance does not cover as this therapy is not approved by the FDA yet. Used extensively in Europe. Cost is similar to monthly medication copays at $60 a vial which lasts one month.