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Download 1. Where are the cell bodies for the preganglionic fibres located in
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1. Where are the cell bodies for the preganglionic fibres located in the spinal cord? Ganglion in PNS and nuclei in CNS 2. What are the sympathetic chain ganglia? Sympathetic pre are short and synapse with cell bodies of post that lie within chain ganglion then synapse with post or travel up chain to post, or pass through chain to form splanchnic nerve into collageral ganglion for abdominal innervation. 3. What does dual innervation mean? Innervation of an organ by both branches of ANS. 4. What are varicosisties? ANS post fibre terminal branches have numerous swellings that simultaneously release neurotransmitter over a large area of the innervated organ. NT diffused from ANS fibres and the electrical signal can spread out through entire organ (cardiac or smooth muscle) via gap junctions. 5. Explain the term sympathomimetic effect. To mimic the effects of the sympathetic nervous system. For example: Thyroid hormone increase target cell responsiveness to catecholamines as does the SNS. 6. Explain how the same neurotransmitter can have ‘opposite effects’ at different tissues in the body when the sympathetic division is activated. Cells respond differently to the same NT as they have different receptors. For example, Nor-‐Adrenaline binds to a1 receptor in blood vessel –constriction and when binds to B2 in urinary bladder relaxes.
