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Chapter 24: Microbial Diseases of the Respiratory System Below you will find answers to the "Review" study questions found at the end of this chapter in Microbiology: An Introduction, 7th edition. 1. Droplet infection. Inhalation of cells and spores; ingestion of contaminated food. 2. Coarse hairs in the nose filter dust particles from inspired air. Mucus traps dust and microorganisms, and cilia move the trapped particles toward the throat for elimination. The ciliary escalator of the lower respiratory system moves particles toward the throat. Alveolar macrophages can phagocytize microorganisms that enter the lungs. IgA antibodies are found in mucus, saliva, and tears. 3. Beta-hemolytic streptococci inhibit growth of pneumococci; faster-growing organisms can compete with pathogens. 4. Mycoplasmal pneumonia is caused by Mycoplasma pneumoniae bacteria. Viral pneumonia can be caused by several different viruses. Mycoplasmal pneumonia can be treated with tetracyclines, whereas viral pneumonia cannot. 5. Bacteria infecting the nose and throat can move through the eustachian tube to the inner ear. Microorganisms can enter the ear directly via swimming pool water or injury to the eardrum or skull. The bacteria that most commonly cause otitis media are S. aureus, Streptococcus pneumoniae, -hemolytic streptococci, and H. influenzae. The middle ear is connected to the nose and throat. 6. Upper Respiratory System Common cold Coronaviruses Sneezing, excessive nasal secretions, congestion 7. Lower Respiratory System Viral pneumonia Several viruses Fever, shortness of breath, chest pains Influenza Influenzavirus Chills, fever, headache, muscular pains RSV Respiratory syncytial virus Coughing, wheezing 8. 9. Amantadine is used to treat influenza. Ribavirin may reduce RSV symptoms. 10. Disease Symptoms Streptococcal pharyngitis Pharyngitis and tonsillitis Scarlet fever Rash and fever Diphtheria Membrane across throat Whooping cough Paroxysmal coughing Tuberculosis Tubercles, weight loss, and coughing Pneumococcal pneumonia Reddish lungs, fever H. influenzae pneumonia Similar to pneumococcal pneumonia Chamydial pneumonia Low fever, cough, and headache Legionellosis Fever and cough Psittacosis Fever and headache Q fever Chills and chest pain Epiglottitis Inflamed, abscessed epiglottis 11. 12. Inhalation of large numbers of spores from Aspergillus or Rhizopus can cause infections in individuals with impaired immune systems, cancer, and diabetes. 13. No. Many different organisms (gram-positive bacteria, gram-negative bacteria, and viruses) can cause pneumonia. Each of these organisms is susceptible to different antimicrobial agents. 14. Disease Endemic Areas in the United States Histoplasmosis States adjoining the Mississippi and Ohio Rivers Coccidioidomycosis American Southwest Blastomycosis Mississippi Pneumocystis Ubiquitous 15. Refer to Table 24.2. 16. In the tuberculin test, purified protein derivative (PPD) from M. tuberculosis is injected into the skin. Induration and reddening of the area around the injection site indicates an active infection or immunity to tuberculosis. 17. Hypothesis 1: Close indoor contact in winter promotes epidemic transmission. Hypothesis 2: The viruses grow best at slightly cooler temperatures. Hypothesis 3: A physiological change in humans during winter allows viral growth. 18. Gram-positive cocci Catalase-positive Staphylococcus aureus -hemolytic Streptococcus pyogenes -hemolytic S. pneumoniae 19. Gram-positive rods Not acid-fast C. diphtheriae Acid-fast Mycobacterium tuberculosis 20. Gram-negative cocci Moraxella catarrhalis 21. Aerobic gram-negative rods Coccobacilli B. pertussis Rods L. pneumophila 22. Facultatively anaerobic gram-negative rods Coccobacilli H. influenzae Rods K. pneumoniae 23. Intracellular Elementary bodies Chlamydia psittaci No elementary bodies Coxiella burnetii 24. Wall-less Mycoplasma pneumoniae 25. Below you will find answers to the "Multiple-Choice" study questions found at the end of this chapter in Microbiology: An Introduction, 7th edition. 1. a 2. c 3. e 4. a 5. c 6. b 7. a 8. e 9. b 10. d Note: The answers to the Critical Thinking and Clinical Applications questions are available to instructors only, and are found in the Instructor's Manual.