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Dunham et al. Table 2.
Table 2. Predicted proteins matching PFAM domains.
Predicted proteins from the annotated genes are listed when they have a matching
domain in the protein domain family database (PFAM).
Protein
Locus Names
PFAM Domain
AP000543.3
dJ347H13.1
ABCD1P4
ACO2
PF00005
PF00330
PF00694
AC000036.1
AP000529.1
AP000355.1
ACR
ACTBL1
ADORA2A
PF00089
PF00022
PF00001
bK407F11.2
ADRBK2
PF00069
PF00169
PF00615
dJ1042K10.1.2
bK58B8.2
ADSL
ADTB1
PF00206
PF01602
bK384D8_1.8
AC005663.1
ARSA
ARVCF
PF00884
PF00514
AP000346.1
dJ1104E15.2
ASLL
ATF4
PF00206
PF00170
bA444G7.1
bA444G7.1
PF00498
U07000.1
BCR
D87002.1
AP000356.5
bK1191B2.3.1
BCRL4
BCRL6
bK1191B2.3
PF00620
PF00621
PF00620
PF00620
PF00698
bK125H2.1
bK125H2.1
PF00612
1
PFAM domain
title
ABC transporter
Aconitase family
(aconitate
hydratase)
Aconitase Cterminal domain
Trypsin
Actin
7 transmembrane
receptor (rhodopsin
family)
Eukaryotic protein
kinase domain
PH domain
Regulator of G
protein signaling
domain
Lyase
Adaptin N terminal
region
Sulfatase
Armadillo/betacatenin-like repeats
Lyase
bZIP transcription
factor
Forkheadassociated (FHA)
domain
RhoGAP domain
RhoGEF domain
RhoGAP domain
RhoGAP domain
Acyl transferase
domain
IQ calmodulinbinding motif
Dunham et al. Table 2.
bK150C2.2
bK150C2.2
PF00383
bK150C2.3
bK150C2.3
PF00383
bK246H3.2
bK246H3.2
PF00058
bK250D10.3
bK250D10.3
PF00735
bK397C4.1
bK397C4.1
PF01084
bK414D7.1
bK414D7.1
PF00307
bK1048E9.2
bK57G9.2
bK445C9.6
bK57G9.2
AC003072.1
bK963H5.1
PF01585
PF00051
PF00431
PF00782
bK984G1.1
bK984G1.1
PF01391
dJ522J7.2
BRD1
dJ172B20.1
CACNA1I
PF00439
PF00628
PF00855
PF00520
dJ293L6.1
CACNG2
PF00822
dJ327J16.3
CBX6
PF00385
dJ742C19.5
CBX7
PF00385
cE132D12.1
dJ1163J1.6
cE132D12.1
CELSR1
PF00071
PF00002
CHKL
PF00008
PF00028
PF00054
PF01633
bK384D8_1.6
2
Cytidine and
deoxycytidylate
deaminase zincbinding region
Cytidine and
deoxycytidylate
deaminase zincbinding region
Low-density
lipoprotein receptor
repeat class B
Cell division
protein
Ribosomal protein
S18
Calponin homology
(CH) domain
G-patch domain
Kringle domain
CUB domain
Dual specificity
phosphatase,
catalytic domain
Collagen triple
helix repeat (20
copies)
Bromodomain
PHD-finger
PWWP domain
Ion transport
protein
PMP22/EMP/MP20
family
'chromo'
(CHRromatin
Organization
MOdifier) domain
'chromo'
(CHRromatin
Organization
MOdifier) domain
Ras family
7 transmembrane
receptor (Secretin
family)
EGF-like domain
Cadherin domain
Laminin G domain
Choline/ethanolami
Dunham et al. Table 2.
AC004463.1
CLTCL1
PF00637
PF01394
bK384D8_1.5
CPT1B
PF00755
AC002470.1
CRKL
PF00017
PF00018
bK445C9.2
CRYBA4
PF00030
bK445C9.1
CRYBB1
PF00030
bK221G9.3
CRYBB2
PF00030
bK221G9.2
CRYBB3
PF00030
bK833B7.2
CSF2RB
PF00041
dJ5O6.1
CSNK1E
PF00069
AP000351.2
DDT
PF01187
dJ434P1.3
DDX17
PF00270
PF00271
AC000095.1
DGCR2
PF00057
dJ222E13.4
DIA1
PF00175
PF00970
dJ100N22.1
dJ1039K5.2
dJ100N22.1
dJ1039K5.2
PF00008
PF01587
dJ1042K10.2.1
dJ1042K10.2
PF00018
dJ1042K10.4
dJ1042K10.4
PF00566
PF00076
3
ne kinase
7-fold repeat in
Clathrin and VPS
Clathrin propeller
repeat
Carnitate
acyltransferase
Src homology
domain 2
Src homology
domain 3
Beta/Gamma
crystallin
Beta/Gamma
crystallin
Beta/Gamma
crystallin
Beta/Gamma
crystallin
Fibronectin type III
domain
Eukaryotic protein
kinase domain
Macrophage
migration
inhibitory factor
(MIF)
DEAD/DEAH box
helicase
Helicases
conserved Cterminal domain
Low-density
lipoprotein receptor
domain class A
Oxidoreductase
FAD/NAD-binding
domain
FAD/NAD-binding
Cytochrome
reductase
EGF-like domain
Monocarboxylate
transporter
Src homology
domain 3
TBC domain
RNA recognition
motif. (a.k.a. RRM,
RBD, or RNP
Dunham et al. Table 2.
dJ1057D18.1
dJ1057D18.1
PF00557
dJ1170K4.2
dJ1170K4.2
PF00057
dJ127B20.3
AC004997.2
dJ149A16.6
dJ127B20.3
dJ130H16.2
dJ149A16.6
PF00089
PF00628
PF00566
PF01139
dJ215F16.1
dJ222E13.3.2
dJ215F16.1
dJ222E13.3
PF00046
PF00076
dJ347H13.2
dJ347H13.2
PF00313
dJ370M22.3
dJ388M5.3
dJ370M22.3
dJ388M5.3
PF01417
PF00685
dJ408N23.2
dJ437M21.2
dJ408N23.2
dJ437M21.2
PF00226
PF01412
dJ466N1.4
dJ526I14.3
dJ569D19.1
dJ63G5.3
dJ466N1.4
dJ526I14.3
dJ569D19.1
dJ63G5.3
PF00023
PF00008
PF00071
PF00560
PF01463
dJ756G23.1
dJ756G23.1
PF00560
dJ786D3.1
dJ90G24.4
dJ786D3.1
dJ90G24.4
PF00036
PF00474
dJ930L11.1
dJ979N1.2
dJ930L11.1
dJ979N1.2
PF00566
PF00096
dJ327J16.1
DNAL4
PF01221
bA247I13.1
bK384D8_1.4
DRG1
ECGF1
PF01018
PF00591
AC000036.3
AC000036.3
PF00595
AC002472.7
AC002472.7
PF00355
4
domain)
metallopeptidase
family M24
Low-density
lipoprotein receptor
domain class A
Trypsin
PHD-finger
TBC domain
Uncharacterized
protein family
UPF0027
Homeobox domain
RNA recognition
motif. (a.k.a. RRM,
RBD, or RNP
domain)
'Cold-shock' DNAbinding domain
ENTH domain
Sulfotransferase
proteins
DnaJ domain
Putative GTP-ase
activating protein
for Arf
Ank repeat
EGF-like domain
Ras family
Leucine Rich
Repeat
Leucine rich repeat
C-terminal domain
Leucine Rich
Repeat
EF hand
Sodium:solute
symporter family
TBC domain
Zinc finger, C2H2
type
Dynein light chain
type 1
GTP1/OBG family
glycosyl transferase
family
PDZ domain (Also
known as DHR or
GLGF).
Rieske (2Fe-2S)
Dunham et al. Table 2.
AC004019.4
AC004019.5
AC004019.4
AC004019.5
PF00439
PF00153
AC004471.4
AC004471.4
PF00069
AC004832.3
AC004832.3
PF00650
AC004832.5
AC004832.5
PF00650
AC005004.1
AC005004.1
PF00610
AC005500.4
AC005500.4
AC006547.2
AC006547.2
PF00651
PF01344
PF00076
AC006548.8
AC007663.2
AC006548.8
AC007663.2
PF00169
PF01619
AC008103.2
AP000344.1
AP000347.3
AP000348.2
AC008103.2
AP000344.1
AP000347.3
AP000348.2
PF00620
PF00135
PF00617
PF00047
AP000350.2
AP000350.2
PF00083
AP000350.5
AP000350.5
PF00043
AP000350.6
AP000350.6
PF00043
AP000351.1
AP000351.1
PF01187
AP000351.11
AP000351.11
PF00043
AP000351.3
AP000351.3
PF00043
AP000351.5
AP000351.5
PF00043
AP000351.7
AP000351.7
PF00043
AP000351.9
AP000351.9
PF01187
5
domain
Bromodomain
Mitochondrial
carrier proteins
Eukaryotic protein
kinase domain
CRAL/TRIO
domain.
CRAL/TRIO
domain.
Domain found in
Dishevelled, Egl10, and Pleckstrin
BTB/POZ domain
Kelch motif
RNA recognition
motif. (a.k.a. RRM,
RBD, or RNP
domain)
PH domain
Proline
dehydrogenase
RhoGAP domain
Carboxylesterases
RasGEF domain
Immunoglobulin
domain
Sugar (and other)
transporter
Glutathione Stransferases.
Glutathione Stransferases.
Macrophage
migration
inhibitory factor
(MIF)
Glutathione Stransferases.
Glutathione Stransferases.
Glutathione Stransferases.
Glutathione Stransferases.
Macrophage
migration
inhibitory factor
(MIF)
Dunham et al. Table 2.
AP000354.2
AP000354.2
PF00307
AP000354.4
AP000356.7
AP000365.2
AP000354.4
AP000356.7
AP000365.2
PF00620
PF01423
PF00153
AP000534.3
AP000534.3
PF00001
AP000547.5
AP000547.5
PF00118
AP000550.2
AP000550.2
PF01019
AP000550.6
AP000552.3
AP000552.5
AP000550.6
AP000552.3
AP000552.5
PF00620
PF00620
PF00018
AP000557.1
AP000557.1
PF00096
AP000557.3
AP000557.3
PF00651
PF00454
AP000557.4
AP000557.4
PF00018
D87002.4
D87002.4
PF01019
D88268.1
D88268.1
PF00560
dJ85F18.1
EP300
PF00439
PF00569
bK984G1.4
EWSR1
PF00076
PF00641
bK941F9.1
fF64F4.1
dJ466N1.3
FBLN1
fF64F4.1
GALR3
PF00008
PF00566
PF00001
dJ466N1.2
GCAT
PF00222
AP000356.4
GGT1
PF01019
6
Calponin homology
(CH) domain
RhoGAP domain
Sm protein
Mitochondrial
carrier proteins
7 transmembrane
receptor (rhodopsin
family)
TCP-1/cpn60
chaperonin family
Gammaglutamyltranspepti
dase
RhoGAP domain
RhoGAP domain
Src homology
domain 3
Zinc finger, C2H2
type
BTB/POZ domain
Phosphatidylinosito
l 3- and 4-kinases
Src homology
domain 3
Gammaglutamyltranspepti
dase
Leucine Rich
Repeat
Bromodomain
Zinc finger present
in dystrophin,
CBP/p300
RNA recognition
motif. (a.k.a. RRM,
RBD, or RNP
domain)
Zn-finger in Ran
binding protein and
others.
EGF-like domain
TBC domain
7 transmembrane
receptor (rhodopsin
family)
Aminotransferases
class-II
Gammaglutamyltranspepti
Dunham et al. Table 2.
AP000354.3
GGTLA1
PF01019
AC000029.1
GNAZ
PF00503
AC000093.2
GP1BB
PF01462
PF01463
bK229A8.3
GPR24
PF00001
dJ370M22.1
GRAP2
PF00017
PF00018
AC004463.3
AP000351.10
GSCL
GSTT1
PF00046
PF00043
AP000350.7
GSTT2
PF00043
dJ508I15.3
GTPBP1
PF00009
dJ466N1.1
H1F0
PF00538
AC007308.3
HCF2
PF00079
AC000085.1
HIRA
PF00400
dJ388M5.2
HMG17L-1
PF01101
bK445C9.3
HMG1L10
PF00505
dJ510H16.2
HMG2L1
PF00505
bK286B10.2
D87023.2
HMOX1
IGLC1
PF01126
PF00047
D87023.4
IGLC2
PF00047
D87017.1
IGLC3
PF00047
D87017.9
IGLC7
PF00047
AP000345.1
IGLL1
PF00047
7
dase
Gammaglutamyltranspepti
dase
G-protein alpha
subunit
Leucine rich repeat
N-terminal domain
Leucine rich repeat
C-terminal domain
7 transmembrane
receptor (rhodopsin
family)
Src homology
domain 2
Src homology
domain 3
Homeobox domain
Glutathione Stransferases.
Glutathione Stransferases.
Elongation factor
Tu family
linker histone H1
and H5 family
Serpins (serine
protease inhibitors)
WD domain, Gbeta repeat
HMG14 and
HMG17
HMG (high
mobility group)
box
HMG (high
mobility group)
box
Heme oxygenase
Immunoglobulin
domain
Immunoglobulin
domain
Immunoglobulin
domain
Immunoglobulin
domain
Immunoglobulin
domain
Dunham et al. Table 2.
AP000347.2
IGLL2
PF00047
bK246H3.1
IGLL3
PF00047
dJ434P1.1
KCNJ4
PF00270
PF00271
PF01007
dJ434P1.2
KDELR3
PF00810
PF01007
bK282F2.1
LARGE
PF01501
dJ37E16.3
LGALS1
PF00337
dJ1177I5.3
LGALS2
PF00337
AC004264.2
AC002073.1c
LIF
LIMK2
PF01291
PF00069
PF00412
PF00595
AC002472.2
LZTR1
KB1027C11.1
MAPK1
PF00651
PF01344
PF00069
dJ402G11.2
MAPK11
PF00069
dJ402G11.1
MAPK12
PF00069
fF62D4.1
bK286B10.3.1
AP000350.3
MB
MCM5
MIF
PF00042
PF00493
PF01187
AP000349.1
MMP11
cE146D10.2
MPST
PF00045
PF00413
PF00581
dJ394A18.1
MTMR3
PF01363
8
Immunoglobulin
domain
Immunoglobulin
domain
DEAD/DEAH box
helicase
Helicases
conserved Cterminal domain
Inward rectifier
potassium channel
ER lumen protein
retaining receptor
Inward rectifier
potassium channel
Glycosyl
transferase family 8
Vertebrate
galactoside-binding
lectins
Vertebrate
galactoside-binding
lectins
LIF / OSM family
Eukaryotic protein
kinase domain
LIM domain
containing proteins
PDZ domain (Also
known as DHR or
GLGF).
BTB/POZ domain
Kelch motif
Eukaryotic protein
kinase domain
Eukaryotic protein
kinase domain
Eukaryotic protein
kinase domain
Globin
MCM2/3/5 family
Macrophage
migration
inhibitory factor
(MIF)
Hemopexin
Matrixin
Rhodanese-like
domain
FYVE zinc finger
Dunham et al. Table 2.
dJ68O2.2
MYH9
PF00063
PF00612
NCF4
PF01576
PF00018
AC000035.1
NEFH
PF00787
PF00038
AC005529.1
NF2
PF00373
bK833B7.1
PF00769
bK216E10.2
NHP2L1
PF01248
dJ327J16.2
dJ430N8.5a
AC004264.1
AC002472.1
AC002472.4
dJ323M22.1
NPTXR
OSBPL1
OSM
P2RXL1
P2RXL2
PACSIN2
PF00354
PF00169
PF01291
PF00864
PF00864
PF00018
PF00611
cN10C3.1
PDGFB
PF00341
AC005006.1
PES1
PF00533
AC007308.1
PIK4CA
PF00454
PF00613
dJ695O20A.2
bK228A9.1
AC000093.1
PKDREJ
PLA2G6
PNUTL1
PF01477
PF00023
PF00735
dJ1039K5.5
POLR2F
PF01192
dJ695O20A.1
PPARA
PF00104
PF00105
AP000553.2
PPIL2
PF00160
9
Myosin head
(motor domain)
IQ calmodulinbinding motif
Myosin tail
Src homology
domain 3
PX domain
Intermediate
filament proteins
FERM domain
(Band 4.1 family)
Ezrin/radixin/moesi
n family
Ribosomal protein
L7Ae
Pentaxin family
PH domain
LIF / OSM family
ATP P2X receptor
ATP P2X receptor
Src homology
domain 3
Fes/CIP4
homology domain
Platelet-derived
growth factor
(PDGF)
BRCA1 C
Terminus (BRCT)
domain
Phosphatidylinosito
l 3- and 4-kinases
Phosphoinositide 3kinase family,
accessory domain
(PIK domain)
PLAT/LH2 domain
Ank repeat
Cell division
protein
RNA polymerases
K / 14 to 18 kDa
subunit
Ligand-binding
domain of nuclear
hormone receptors
Zinc finger, C4
type (two domains)
Cyclophilin type
Dunham et al. Table 2.
dJ1039K5.1
PRKCABP
PF00595
bK384D8_1.7
PRKM8IPL
PF00018
PF00640
AC008103.1
PRODH
PF01619
dJ63G5.1
PSCD4
AC004832.2
PTPNS1L
PF00169
PF01369
PF00047
fF24E5.1
AC000102.1
AC002055.1
dJ151B14.2
AC006547.1
dJ756G23.2
PVALB
RAB36
RABL2B
RAC2
RANBP1
RANGAP1
PF00036
PF00071
PF00071
PF00071
PF00638
PF00560
dJ41P2.1
RBM9
PF00076
AC000025.3
RFPL1
PF00097
dJ90G24.1
RFPL2
PF00622
PF00097
dJ149A16.2
RFPL3
PF00622
PF00097
dJ333H23.1.1
RPL3
PF00622
PF00297
cB1E7.2
bA12M9.1
RPS17L4
RPS9L1
PF00833
PF00163
SBF1
SEC14L2
PF01479
PF00169
PF00650
dJ579N16.2
AC004997.5
10
peptidyl-prolyl cistrans isomerase
PDZ domain (Also
known as DHR or
GLGF).
Src homology
domain 3
Phosphotyrosine
interaction domain
(PTB/PID).
Proline
dehydrogenase
PH domain
Sec7 domain
Immunoglobulin
domain
EF hand
Ras family
Ras family
Ras family
RanBP1 domain.
Leucine Rich
Repeat
RNA recognition
motif. (a.k.a. RRM,
RBD, or RNP
domain)
Zinc finger,
C3HC4 type
(RING finger)
SPRY domain
Zinc finger,
C3HC4 type
(RING finger)
SPRY domain
Zinc finger,
C3HC4 type
(RING finger)
SPRY domain
Ribosomal protein
L3
Ribosomal S17
Ribosomal protein
S4/S9 N-terminal
domain
S4 domain
PH domain
CRAL/TRIO
domain.
Dunham et al. Table 2.
dJ268D13.1
SEZ6L
PF00084
AC004997.3
SF3a120
dJ37E16.2
AC004463.2
SH3BP1
SLC25A1
PF00431
PF00240
PF01805
PF00620
PF00153
dJ362J20.1
SLC25A17
PF00153
cB1E7.1
SLC5A1
PF00474
AC002472.5
SLC7A4
PF00324
AC005005.2
SMTN
PF00307
AC007308.2
dJ1039K5.4
SNAP29
SOX10
PF00835
PF00505
bK250D10.1
SREBF2
PF00010
dJ151B14.3
SSTR3
PF00001
dJ408N23.1
AC004471.3
ST13
STK22A
PF00515
PF00069
dJ407F17.1
TAB1
PF00481
AC000091.1a
AC005006.3
TBX1
TCN2
PF00907
PF01122
dJ979N1.1
TEF
PF00170
dJ309I22.1
TIMP3
PF00965
dJ510H16.1
D87012.1
TOM1
TOP3b
PF00790
PF01131
AC000078.1
TR
PF01751
PF00070
bK223H9.1
cE146D10.1
TROB2
TST
PF01211
PF00581
11
Sushi domain (SCR
repeat)
CUB domain
Ubiquitin family
Surp module
RhoGAP domain
Mitochondrial
carrier proteins
Mitochondrial
carrier proteins
Sodium:solute
symporter family
Amino acid
permease
Calponin homology
(CH) domain
SNAP-25 family
HMG (high
mobility group)
box
Helix-loop-helix
DNA-binding
domain
7 transmembrane
receptor (rhodopsin
family)
TPR Domain
Eukaryotic protein
kinase domain
Protein
phosphatase 2C
T-box
Eukaryotic
cobalamin-binding
protein
bZIP transcription
factor
Tissue inhibitor of
metalloproteinases
VHS domain
Prokaryotic DNA
topoisomerase
Toprim domain
Pyridine
nucleotidedisulphide
oxidoreductase
class-I
BTG1 family
Rhodanese-like
Dunham et al. Table 2.
AC008101.1
TUBAL2
PF00091
dJ1119A7.1
dJ370M22.2
TXN2
UQCRFSL1
PF00085
PF00355
AC005500.1
USP18
PF00442
PF00443
D88270.1
VPREB1
PF00047
bK292E10.1
XBP1
PF00170
cN44A4.1
AC005003.3
YWHAH
ZNF278
PF00244
PF00096
D87009.3
ZNF279
PF00651
PF00096
D87009.4
ZNF280
PF00096
AP000348.1
ZNF70
PF00096
AC007731.1
ZNF74
PF00096
PF01352
12
domain
Tubulin/FtsZ
family
Thioredoxin
Rieske (2Fe-2S)
domain
Ubiquitin carboxylterminal hydrolases
family 2
Ubiquitin carboxylterminal hydrolases
family 2
Immunoglobulin
domain
bZIP transcription
factor
14-3-3 proteins
Zinc finger, C2H2
type
BTB/POZ domain
Zinc finger, C2H2
type
Zinc finger, C2H2
type
Zinc finger, C2H2
type
Zinc finger, C2H2
type
KRAB box