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Chapter 15 Urinary System Kidney Anatomy -Hillus -Renal cortex -Renal Medulla -Medullary pyramids -Renal Columns -Renal Pelvis -Calyces Blood Supply and Path -Enters kidney via Renal Artery, branches into smaller vessels: -Glomerulus is sight of filtration, blood leaves glomerulus and head towards venous system. Anatomy of a Nephron -A Nephron consists of: -Glomerulus -Proximal convoluted tubule -Loop of Henle 1 -Distal convoluted tubule -Collecting ducts -Glomerulus capillaries and peritubular capillaries -juxtaglomerular apparatus Urine Formation -Urine Formation is the result of three processes, filtration, reabsorption, and secretion. -Filtration- -Reabsorption- -Secretion- Characteristics of Urine -Yellow color is due to broken down remains of hemoglobin -Urine is sterile and slightly aromatic when formed -Slightly acidic (pH 6) *changes in diet can change pH* -Slightly higher specific gravity than water -Changes in urine characteristics can be diagnostic of certain conditions 2 Ureters- Urinary Bladder-TrigoneUrethra- Micturation- Fluid, Electrolyte, Acid-Base Balance 4 roles in maintaining blood composition 1. excretion of nitrogenous wastes 2. maintaining water balance 3. maintaining water balance 4. ensuring proper blood pH Water and Electrolyte Balance -Fluid is contained in two compartments 1. Intracellular fluid volume2. Extracellular fluid-Electrolyte-kidneys regulate water and electrolyte concentrations -Reabsorption of water and electrolytes by the kidneys are regulated primarily by hormones. 3 Acid-Base Balance -Blood must be between 7.35 and 7.45 pH -Acids and bases are released by cellular metabolism -Kidneys, blood buffers, and respiratory system all work to maintain acid/base balance. Blood Buffers -involves bicarbonate, phosphate, and protein buffers HCl + NaHCO3 H2CO3 + NaCl NaOH + H2CO3 NaHCO3 + H2O Respiratory Buffers -Uses gas exchange at the lungs to release CO2 CO2 + H2O H2CO3 H+ + HCO3 - Renal Mechanisms -In acidic conditions: -In basic conditions: 4