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Demon in the Freezer and Cobra Event Project Honors Biology –Spring 2012 Demon in the Freezer -100 points – due March 30, 2012 1. Describe the eradication of smallpox. Why was smallpox chosen to be eradicated, when was it last found in nature, which agencies were involved in the eradication? Along with the description, include an illustration to describe the ring containment method utilized. 2. Research the lytic and lysogenic cycle of a virus. Draw both cycles each on a sheet of plain white paper (by hand). Label the cycles and explain both of the processes in detail. 3. Design a new cover for the book that illustrates what has impressed you the most. (Drawing the same cover as on the book or simply one of the pictures included in the novel will not earn you credit. I am looking for thought and reflection of what you have read.) 4. Explain the purpose of storing smallpox. Where is smallpox stored and how could it be used as a bioweapon? In your opinion, should smallpox be stored? Why? (Be specific and explain your opinion in detail.) 5. In a chart, provide the types of smallpox that infected humans, the symptoms caused by each type, and the likelihood of death associated with each. 6. Make a pamphlet about vaccinations and include the following: how a vaccination works, the function of B and T cells in the immune system, the difference between active and passive immunity, and a description of Jenner’s contributions to vaccinations. 7. Explain a cytokine storm. 8. Write and support an opinion statement on the use of animals in medical research. When might it be necessary? Are there regulations against using animals today? Why were monkeys used in smallpox research? 9. The novel discusses both anthrax and smallpox. Using information related to these two infectious agents, create a Venn diagram to compare and contrast a virus and a bacterium. 10. The last statement in the Demon in the Freezer is as follows: “We could eradicate smallpox from nature, but we could not uproot the virus from the human heart. Give your thoughts and opinions on this statement. The Cobra Event -100 points – due May 18, 2012 1. As you read, make a list of “SAT” terms. These should be words you do not know the meaning of initially, but might possibly see again. Use the sentences around the terms or a dictionary to find the meaning of these terms. You should have a minimum of 20 terms and no proper nouns may be used. 2. Design a new cover for the book that illustrates what has impressed you the most. (Drawing the same cover as on the book or simply one of the pictures included in the novel will not earn you credit. I am looking for thought and reflection of what you have read.) 3. Make a time line of all infections in the book (who had the disease 1st, 2nd, etc.), 4. Make a second time line of the disease once an individual is infected. (A time line in this case would show a sequence or series of events, not specific dates.) 5. Using the world map provided, label the cities that the book mentions. 6. What happens to a human infected with brainpox? Describe the classic final seizure in detail. 7. Describe what a bioreactor does and how it works. 8. The brainpox is a combination of three different viruses. Describe each and why it was chosen by Archimedes to be used for the weapon. 9. Using analogies from the book, describe how New York is like a living organism. 10. Explain the concept of and the methods use in performing genetic engineering. Why is this a threat with viruses like smallpox? Comparative Essay -25 points – due May 29, 2012 Compare and contrast the two books. Discuss how the author’s approach is different and possibly the same. Compare and contrast the viruses found in both books. Finally, utilize information from your textbook and other sources and write a one page minimum paper answering the following question: “Are viruses alive?” Include a discussion of the characteristics of life and those characteristics that both living and nonliving things share. This section should be completed in a minimum of two pages, typed, double-spaced, in 12 point Times New Roman font, with 1 inch margins on all sides. Be detailed and do not hesitate to add more than what is asked for. Submission of Project Sections of the project WILL NOT be accepted late for any reason. The requirements for each novel should be submitted in a folder with the student’s name on the front cover. The folder should have pockets/prongs to keep assignments from falling out. Do not place assignments in sheet protectors for submission.