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ORIGINAL ARTICLES PUBLISHED JULY 1, 2004 – JUNE 30, 2005 Adam H, Nichol K, Hoban DJ and Zhanel GG. Stability of fluoroquinolone resistance in Streptococcus pneumoniae clinical isolates and laboratory-derived mutants. Antimicrobial Agents and Chemotherapy 2004;49:846-848. Alfa MJ, Castillo J. Impact of FDA policy change on the reuse of single-use medical devices in Michigan hospitals. Am J Infect Contr 2004Oct;32(6):337-41. Alfa MJ, Nemes R. Manual versus automated methods for cleaning reusable accessory devices used for minimally invasive surgical procedures. J Hosp Infect 2004Sep;58(1):50-8. Alfa MJ. The laboratory diagnosis of Haemophilus ducreyi. Can J Infect Dis Med Microbiol 2005; 16(1): 3134. Alimonti JB, Koesters SA, Kimani J, Matu L, Wachihi C, Plummer FA and Fowke KR. CD4+ T cell responses in HIVexposed seronegative subjects are qualitatively distinct from those in HIV-infected individuals. J Infect Diseases. 2005. 191:20-4. Ao Z, Fowke KR, Cohen EA, Yao X. Contribution of the C-terminal tri-lysine regions of human immunodeficiency virus type 1 integrase for efficient reverse transcription and viral DNA nuclear import. Retrovirology. 2005, 2:62. Ariano RE, Nyhen A, Donnelly JP, Sitar DS, Harding GKM, Zelenitsky SA. Pharmacokinetics and Pharmacodynamics of Meropenem in Febrile Neutropenic Patients with Bacteremia. Annals of Pharmacother. 2005; 39:32-38. Artsob H. (2004). Emerging and nonemerging arboviral diseases and the veterinary/public health interface. Can. Vet. J. 45: 1021-1022. Athamna A, Athamna M, Abu-Rashed N, Medlej B, Bast DJ, Rubinstein E. Selection of Bacillus anthracis isolates resistant to antibiotics. J Antimicrob Chemother 2004;54:424-8. Athamna A, Athamna M, Medlej B, Bast DJ, Rubinstein E. In vitro post-antibiotic effect of fluoroquinolones, macrolides, beta-lactams, tetracyclines, vancomycin, clindamycin, linezolid, chloramphenicol, quinupristin/dalfopristin and rifampicin on Bacillus anthracis. J Antimicrob Chemother 2004;53:609-15. Athamna A, Athamna M, Nura A, Shlyakov E, Bast DJ, Farrell D, Rubinstein E. Is In Vitro Antibiotic Combination More Effective than Single-Drug Therapy against Anthrax? Antimicrob Agents Chemother 2005;494:1323-5. Athamna A, Massalha M, Athamna M, Nura A, Medlej B, Ofek I, Bast D, Rubinstein E. In vitro susceptibility of Bacillus anthracis to various antibacterial agents and their time-kill activity J Antimicrob Chemother. 2004 53: 247251. Aziz S, Tam T, Macey JF, Li Y, Jain S, Boulos D, Zheng H, Winchester B, and Zabchuk P. (2005). Influenza in Canada: 2003-2004 season. Can Commun Dis Rep. 31(1): 1- 17. Bai H, J. Yang, H. Hiu, S. Wang, Y. Fan, X. Han, S. Xie and X. Yang. Intranasal inoculation of Chlamydia trachomatis mouse pneumonitis agent (MoPn) induces significant neutrophil infiltration which is not efficient in controlling the infection in mice. Immunology, 114:246-254, 2005. Bai H, J. Yang, H. Qiu, S. Wang, Y. Fan and X. Yang. Expression of proinflammatory cytokines following chlamydia trachomatis lung infection. Immunol. J (Chin). 8:119-124, 2004. Bai H, J. Yang, H. Qiu, S. Wang, Y. Fan and X. Yang. Production of MIP-1 and MCP chemotactic cytokines following Chlamydia trachomatis lung infection and its relationship with host immune defence. Chin. J. Immunol. 23:110-114 2004. Bakhanashvili M, Novitsky E, Rubinstein E, Levy I, Rahav G. Excision of Nucleoside Analogs from DNA by p53 Protein, a Potential Cellular Mechanism of Resistance to Inhibitors of Human Immunodeficiency Virus Type 1 Reverse Transcriptase. Antimicrob Agents Chemother 2005;494:1576-9. Ball AP, Bartlett JG, Craig WA, Drusano GL, Felmingham D, Garau JA, Klugman KP, Low DE, Mandell LA, Rubinstein E, Tillotson GS. Future trends in antimicrobial chemotherapy: expert opinion on the 43rd ICAAC. J Chemother. 2004 Oct; 16(5):419-36. Review. Banus HA, van Kranen HJ, Mooi FR, Hoebee B, Nagelkerke NJ, Demant P, Kimman TG. Genetic control of Bordetella pertussis infection: identification of susceptibility loci using recombinant congenic strains of mice. Infect Immun. 2005 Feb;73(2):741-7. Barrau K, Boulamery A, Imbert G, Casalta JP, Habib G, Messana T, Bonnet JL, Rubinstein E, Raoult D. Causative organisms of infective endocarditis according to host status Clin Microbiol Infect. 2004;10:302-8. Bast DJ, Athamna A, Duncan CL, de Azavedo JC, Low DE, Rahav G, Farrell D, Rubinstein E. Type II topoisomerase mutations in Bacillus anthracis associated with high-level fluoroquinolone resistance. J Antimicrob Chemother 2004 ;54:90-4. Bastien N, Anderson K, Hart L, Milley D, Brandt K, Van Caeseele P, Hatchette H, and Li Y. (2005) Human Coronavirus NL-63 Infection in Canada. J Infect Dis. 191: 503 - 506. Baucheron S., S. Tyler, D. Boyd, M. R. Mulvey, E. Chaslus-Dancla, A. Cloeckaert . 2004. AcrAB-TolC directs effluxmediated multidrug resistance in Salmonella enterica serovar typhimurium DT104 Antimicrob Agents Chemother. 48:3729-3735. Beattie T, Kaul R, Rostron T, Dong T, Easterbrook P, Jaoko W, Kimani J, Plummer F, McMichael A, Rowland-Jones S. Screening for HIV-specific T-cell responses using overlapping 15-mer peptide pools or optimized epitopes. AIDS 2004;18(11):1595-8. Ben David D, Rahav G & Rubinstein E. Future antibiotics and current practices for treating respiratory tract infections. Europ Respir J 2004. Berhane Y, Berry JD, Ranadheera C, Marszal P, Nicolas B, Yuan X, Czub M, Weingartl H.: Production and characterization of monoclonal antibodies against binary ethylenimine inactivated Nipah virus. J Virol Methods. 2005. Bernard, K.A. 2005. Corynebacterium species and coryneforms. An update on taxonomy and diseases attributed to these taxa Clin. Microbiol. Newslett. 27:9-18 [invited review]. Bernstein DI, Aoki FY, Tyring SK, Stanberry LR, St-Pierre C, Shafran SD, Leroux-Roels G, Van Herck K, Bollaerts A and Dubin G for the GlaxoSmithKline Herpes Vaccine Study Group. Safety and immunogenicity of glycoprotein-Dadjuvant genital herpes vaccine. Clin Inf Dis 2005; 40:1271-1281. Berry JD, Jones S, Drebot MA, Andonov A, Sabara M, Yuan XY, Weingartl H, Fernando L, Marszal P, Gren J, Nicolas B, Andonova M, Ranada F, Gubbins MJ, Ball TB, Kitching P, Li Y, Kabani A, Plummer F. Development and immunochemical characterization of neutralizing monoclonal antibodies to the SARS-coronavirus (SARS-hCoV). J Virol Meth 2004;120:87-96. Bertelsen MF, Olberg RA, Crawshaw GJ, Dibernardo A, Lindsay LR, Drebot M, Barker IK. (2004). West Nile virus infections in the eastern loggerhead shrike (Lanius ludovicianus migrans): pathology, epidemiology, and immunization. J Wildl Dis 40: 538-42. Blackwood, KS, TV Burdz, CY Turenne, MS Sharma, AM Kabani and JN Wolfe. 2005. Viability testing of material derived from Mycobacterium tuberculosis prior to removal from a containment level III as part of a laboratory risk assessment. BMC Infect. Dis. 5:4. Blanchard JF, O’Neil JD, Ramesh BM, Bhattacharjee P, Orchard T, Moses S. Understanding the social and cultural context of female sex work in Karnataka, India: implications for HIV prevention. J Infect Dis 2005; 191(Suppl 1):S139-46. Booth S, Bowman C, Baumgartner R, Dolenko B, Sorensen G, Robertson C, Coulthart M, Phillipson C, Somorjai R. Molecular classification of scrapie strains in mice using gene expression profiling. Biochemical and Biophysical Research Communications 2004;325:1339-45. Booth S, C. Bowman, R. Baumgartner, G. Sorensen, C. Robertson, M. Coulthart, C. Phillipson and R. L. Somorjai. Identification of central nervous system genes involved in the host response to the scrapie agent during clinical and pre-clinical infection. J. Gen. Virol. 85, 3459-3471. Booth, T. F., B. Kournikakis, N. Bastien, J. Ho, D. Kobasa, L. Stadnyk, Y. Li, M. Spence, S. Paton, B. Henry, B. Mederski, D. White, D. E. Low, A. McGeer, A. Simor, M. Vearncombe, J. Downey, F. B. Jamieson, P. Tang, and F. Plummer. 2005. Detection of airborne severe acute respiratory syndrome (SARS) coronavirus and environmental contamination in SARS outbreak units. J.Infect.Dis. 191, no. 9:1472-1477. Boulos D., Goedhuis N.J., Wu J., Baptiste B., Poliquin D., Furseth J., Chan J., Bolesnikov G., Barichello F., Andonov A., Giulivi A. (2005) Enhanced surveillance for acute and likely acute hepatitis B in Canada: 1999 to 2002. Canadian Journal of Infectious Diseases and Medical Microbiology, 16 (5), 275-281. Bow EJ. Long-term antifungal prophylaxis in high-risk hematopoietic stem cell transplant recipients. Medical Mycology 2005: (43) Suppl 1: S277-S287. Bow EJ. Management of the febrile neutropenic cancer patient: lessons from 40 years of study. Clin Microbiol Infect. 2005: (11) Suppl 5:24-29. Boyd, D. A., S. Tyler, S. Christianson, A. McGeer, M. P. Muller, B. M. Willey, E. Bryce, M. Gardam, P. Nordmann, M. R. Mulvey. and the Canadian Nosocomial Infection Surveillance Program, Health Canada. 2004. Complete Nucleotide Sequence of a 92-kb Plasmid Harboring the Extended Spectrum Beta-Lactamase CTX-M-15 Involved in a Long-term Care Outbreak in Toronto. Antimicrobial Agents and Chemotherapy. 48:3758-3764. Boyd, D., P. Kibsey, D. Roscoe, M. R. Mulvey and the Canadian Nosocomial Infection Surveillance Program (CNISP). 2004. Enterococcus faecium N03-0072 carries a new VanD-type vancomycin resistance; characterization of the vanD5 operon. Journal of Antimicrobial Chemotherapy. 54:680-683. Busch MP, Tobler LH, Saldanha J, Caglioti S, Venkatakrishna S, Linnen J, Gallarda Phelps B, Smith R, Drebot M, Kleinman SH. (2005). Analytical and clinical sensitivity of first generation West Nile virus screening and confirmation assays. Transfusion 45: 492-499. Cahane M, Ben Simon GJ, Barequet IS, Grinbaum A, Diamanstein-Weiss L, Goller O, Rubinstein E, Avni I. Human corneal stromal tissue concentration after consecutive doses of topically applied 3.3% vancomycin. Br J Ophthalmol 2004;88:22-4. Carletti F, Di Caro A, Calcaterra S, Grolla A, Czub M, Ippolito G, Capobianchi MR, Horejsh D. Rapid, differential diagnosis of orthopox- and herpesviruses based upon real-time PCR product melting temperature and restriction enzyme analysis of amplicons. J Virol Methods. 2005;129(1):97-100. Carlson, J.H., Hughes, S., Hogan, D., Cieplak,G., Sturdevant, D.E., McClarty, G., Caldwell, H., Belland, R.J. 2004. Polymorphisms in the Chlamydia trachomatis Cytotoxin Locus Correlate with Pathological Groups. Infect. Immun. 72:7063-7072 Carrie AC, Metge C, Collins D, Harding GKM and Zhanel GG. Use of administrative healthcare claims to examine the effectiveness of trimethoprim-sulfamethoxazole versus fluoroquinolones in the Treatment of community-acquired pyelonephritis. Journal of Antimicrobial Chemotherapy 2004;53:512-517. Carrie AC, Metge C, Collins DM, Harding GKM and Zhanel GG. Predictors of receipt of a fluoroquinolone versus trimethoprim-sulfamethoxazole for treatment of acute pyelonephritis in women in Manitoba Canada. Pharmacoepidemiology and Drug Safety 2004; Feb 10:22-33. Castellsague X, Peeling RW, Franceschi S, de Sanjose S, Smith JS, Albero G, et al. for the IARC Multicenter Cervical Cancer Study Group. Chlamydia trachomatis infection in Female Partners of circumcised and Uncircumcised Adult Men. Am J Epidemiol 162:907-16, 2005. Chen Z, Mustafa T, Trojanowicz B, Brauckhoff M, Gimm O, Schmutzler C, Kohrle J, Holzhausen HJ, Kehlen A, Klonisch T, Finke R, Dralle H, Hoang-Vu C (2004) CD82, and CD63 in thyroid cancer. Int J Mol Med.,14: 517-27. Chernesky MA, Patrick D, Peeling R, eds. Canadian Infectious Disease Society. Canadian laboratory standards for sexually transmitted infections: Best practice guidelines. Can J Infect Dis 16: 2005. Clark CG, Bryden L, Cuff WR, Johnson PL, Jamieson F, Ciebin B, Wang G. 2005. Use of the Oxford multilocus sequence typing protocol and sequencing of the flagellin short variable region to characterize isolates from a large oubreak of waterborne Campylobacter sp. strains in Walkerton, Ontario, Canada. J Clin Microbiol 43:2080-2091. Cooper CL, Davis HL, Morris ML, Efler SM, Krieg AM, Li Y, Laframboise C, Adhami Al, Khaliq Y, Seguin I and Cameron DW (2004). Safety and immunogenicity of CPG 7909 injection as an adjuvant to fluarix influenza vaccine. Vaccine 22:3136-3143. Coulthart MB, Posada D, Crandall KA, Dekaban GA. On the Phylogenetic Placement of Human T Cell Leukemia Virus Type 1 Sequences Associated with an Andean Mummy. Infection, Genetics and Evolution 2006;6:91-6 (published online March 23, 2005). Cowan FM, Hargrove J, Langhaug LF, Jaffar S, Mhuriyengwe L, Swarthout TD, Matsikire E, Peelng RW, Latif A, Bassett M, Brown DWG, Mabey D, Hayes RJ, Wilson D. The appropriateness of core group interventions using presumptive periodic treatment among rural Zimbabwean women who exchange sex for gifts or money. J. AIDS 38:202-7, 2005. Cowan FM, Lanhaug L, Hargrove J, Jaffar S, Mhuriyengwe L, Swarthout TD, Matsikire E, Peeling RW, Latif A, Bassett M, Brown DWG, Mabey D, Hayes RJ, Wilson D. Is contact with sex workers important in driving the HIV epidemic in rural Zimbabwe? J. AIDS 40:371-6, 2005. Czub M, Weingartl H, Czub S, He R, Jingxin C: Evaluation of modified vaccinia virus Ankara based recombinant SARS vaccine in ferrets. Vaccine. 2005;23(17-18):2273-9. Czub Markus, Hana Weingartl, Stephanie Czub, Runtao He, Jingxin Cao (corresponding author). Evaluation of modified vaccinia virus Ankara based recombinanr SARS vaccine in ferrets. Vaccine 2005, 23(17-18):2271-2277. Czub, S, Czub, M, Koutsilieri, E, Sopper, S, Villinger, F, Muller, JG, Stahl-Hennig, C, Riederer, P, Ter Meulen, V, Gosztonyi, G.: Modulation of simian immunodeficiency virus neuropathology by dopaminergic drugs. Acta Neuropathol (Berl). 2004;107(3):216-26. Daddario KM, Gutieri MC, Mothe BR, Larsen T, Hensley LE, Jahrling PB, Feldmann H (2005). Development of a new vaccine for the prevention of Lassa fever. Plos Med. 2: 537-545. Dagan R, Regev-Yochay G, Rubinstein E. Resistant organisms and otitis media. Pediatr Infect Dis J. 2005 Sep;24(9):849. David ST, Skowronski DM, Tweed A, Tuk TA, Danderfer GJ, Li Y, Krajden M, Petric M, McNabb G, and Gillies R (2005).Epidemiologic profile of a new H3N2 variant of influenza A mismatched to vaccine in 2003-2004. Can Commn Dis Rep.31: 21-31. de Bock GH, Jacobi CE, Jonker MA, Nagelkerke NJ, van Houwelingen JC. A breast cancer prediction model. Stat Med. 2005 May 30;24(10):1610-2; author reply 1612. DeMiranda JR, Drebot M, Tyler S, Shen M, Cameron CE. (2004). Complete nucleotide sequence of Kashmir bee virus and comparison with acute bee paralysis virus. J Gen Virol. 85(Pt 8):2263-70. Doublet D., D. Boyd, M. R. Mulvey, and A. Cloeckaert. 2005. The Salmonella genomic island 1 is an integrative mobilizable element. Molecular Microbiology. 55:1911-1924. Doublet, B., P. Butaye, H. Imberechts, D. Boyd, M. R. Mulvey, E. Chaslus-Dancla, and A. Cloeckaert. 2004. Characterization of Salmonella genomic island 1 multidrug resistance gene clusters from S. enterica serovar Agona, Belgium, 1992-2002. Antimicrob. Agents Chemother. 48:2510-2517. Dow G, Alfa M, Harding GKM, Nicolle LE (letter). Reinfection versus relapse in urinary infection. Clin Infect Dis 2005; 40:495-496. Dow G, Rao P, Harding G, Brunka J, Kennedy J, Alfa M, Nicolle LE. A prospective, randomized trial of three or fourteen days ciprofloxacin for acute urinary infection in patients with spinal cord injury. Clin Infect Dis 2004; 39:658-664. Drebot, M. & Artsob H (2005). West Nile virus. Can Fam Physician 51: 1094-1099. Du T, Alfa MJ. Translocation of Clostridium difficile toxin B across polarized CaCo-2 cell monolayers is enhanced by toxin A. Can J Infect Dis 2004;15(2):83-88. Embree J. The impact of HIV/AIDS on children in developing countries. Paediatr Child Health 10: 261-263, 2005. Eyal, M., Rubinstein, E. Poliomyelitis – Current Status. Inf Dis Prac for Clinicians p414-16, Jun 2005. Feldmann H, Wahl-Jensen V, Jones SM, Stroeher U (2004). Ebola virus ecology: a continuing mystery. Trends. Microbiol. 12: 433-437. Ferguson A, Moses S, Morris C, et al, Sexual patterning and condom use among a group of HIV-vulnerable men in Thika, Kenya, Sexually Transmitted Infections. 2004 Dec;80(6):435-9. Ferguson A, Pere M, Morris C, Ngugi E, Moses S. Sexual patterning and condom use among a group of HIVvulnerable men in Thika, Kenya; Sex Transm Infect 2004; 80:435-9. Flick K, Katz A, Overby A, Feldmann H, Pettersson RF, Flick R (2004). Functional analysis of the noncoding regions of the Uukuniemi virus (Bunyaviridae) RNA segments. J. Virol. 78: 11726-11738. Foss A, Vickerman P, Ramesh BM, Moses S, Blanchard J, Watts C. The potential impact of microbicides in Bagalkot District, Karnataka, India: model projections and implications for product promotion. London: International Family Health, 2004. Fowler VG Jr, Miro JM, Hoen B, Cabell CH, Abrutyn E, Rubinstein E, Corey GR, Spelman D, Bradley SF, Barsic B, Pappas PA, Anstrom KJ, Wray D, Fortes CQ, Anguera I, Athan E, Jones P, van der Meer JT, Elliott TS, Levine DP, Bayer AS; ICE Investigators. Staphylococcus aureus endocarditis: a consequence of medical progress. JAMA 2005 Jun 22;293 (24):3012-21. Geisbert TW, Jones S, Fritz EA, Shurtleff AC, Geisbert JB, Liebscher R, Grolla A, Stroeher U, Fernando L, Gelmon LJ, Costigan A, Singh P, Bhattacharjee P; How to Run a District-Wide HIV and AIDS Prevention and Care Programme: Case Studies of Two Projects in Low Prevalence Ajmer District, Rajasthan and High-Prevalence Bagalkot District, Karnataka; ICHAP Publication, Jaipur/Bangalore, 2005 Gelmon LJ, Costigan A, Singh P, Chatterjee P; Building State Preparedness to Address HIV and AIDS, Rajasthan: A Case Study; ICHAP Publication, Jaipur, 2005 Gelmon, LJ; The Bagalkot Experience: Addressing HIV/AIDS Risk and Vulnerability in a Rural India Setting; ICHAP Publication, Bangalore, 2004 Geubbels EL, Wille JC, Nagelkerke NJ, Vandenbroucke-Grauls CM, Grobbee DE, de Boer AS. Hospital-related determinants for surgical-site infection following hip arthroplasty. Infect Control Hosp Epidemiol. 2005 May;26(5):435-41. Gilbert, R. A., Tomkins, N., Padmanabha, J., Gough, J., Hunter, R. A., Krause, D.O., and McSweeney, C. S. (2005) Effect of finishing diets on Escherichia coli populations and prevalence of EHEC virulence genes in cattle faeces. J. Appl. Microbiol. 99: 311-320. Gilmour MW, Thomson NR, Sanders M, Parkhill J, Taylor DE. 2004. The complete nucleotide sequence of R478: defining the backbone components of incompatibility group H conjugative plasmids through comparative genomics. Plasmid. 52(3):182-202. Gilmour, M. W., T. Cote, J. Munro, L. Chui, J. Wylie, J. Isaac-Renton, G. Horsman, D. M. Tracz, A. Andrysiak and L.-K. Ng. 2005. Multilocus Sequence Typing of Escherichia coli O26:H11 Isolates Carrying stx in Canada Does Not Identify Genetic Diversity. Journal of Clinical Microbiology. 43(10):1. Godin B, Touitou E, Rubinstein E, Athamna A, Athamna M. A new approach for treatment of deep skin infections by an ethosomal antibiotic preparation: an in vivo study. J Antimicrob Chemother 2005 Jun; 55 (6):989-94. Gozho GN, Plaizier JC, Krause DO, Kennedy AD, Wittenberg KM. (2005) Subacute ruminal acidosis induces ruminal lipopolysaccharide endotoxin release and triggers an inflammatory response. J Dairy Sci. 88:1399-1403. Greene, W., Xiao, Y.,Huang, Y., McClarty, G. and Zhong, G. 2004 Chlamydia infected cells continue to undergo mitosis and resist apoptosis induction. Infect. Immun. 72:451-60. Griffin, J., Roshick, C. Iliffe-Lee, E., and McClarty, G. 2005. Catalytic Mechanism of Chlamydia trachomatis Flavin Dependent Thymidylate Synthase. J. Biol. Chem. 280:5456-5467. Grose C, S Tyler, G Peters, J Hiebert, GW Stephens, WT Ruyechan, W Jackson, J Storlie and GA Tipples. Complete DNA sequence analyses of the first two varicella-zoster virus glycoprotein E (D150N) mutant viruses found in North America: Evolution of genotypes with an accelerated cell spread phenotype. J Virol 78:6799-807 (2004). Groseth A, Feldmann H, Theriault S, Mehmetoglu G, Flick R (2005). RNA polymerase I-driven minigenome system for Ebola viruses. J. Virol. 79: 4425-4433. Gubbins M, Plummer FA, Yuan XY, Johnstone D, Drebot M, Andonova M, Andonov A, Berry JD. Molecular ccharacterization of a panel of murine monoclonal antibodies specific for the SARS-coronavirus. Molec Immunol 2005;42:125-36. Haferkamp S, Fernando L, Schwarz TF, Feldmann H, Flick R (2005). Intracellular localization of Crimean-Congo hemorrhagic fever (CCHF) virus glycoproteins. Virol. Journal 25: 42. Harding GAJ, Bow EJ. Commentary. Infectious Complications of Lung Cancer. Oncology 2005;19(2):195-99. Harper DM, Franco LF, Wheeler C, Ferris DG, Jenkins D, Schuind A, Zahaf T, Innis B, Naud P, De Carvalho NS, RoteliMartins CM, Teizeira J, Blatter MM, Korn AP, Quint W, Dubin G for the GlaxoSmithKline HPV Vaccine Study Group (Aoki FY, member). Efficacy of a bivalent L1 virus-like particle vaccine in prevention of infection with human papillomavirus types 16 and 18 in young women: a randomised controlled trial. The Lancet 2004; 364:1757-1765. Hatch, G. and McClarty, G. 2004 Chlamydia trachomatis infection accelerates phosphatidylcholine metabolism derived from low density lipoprotein but does not affect phosphatidylcholine secretion. BMC Microbiol. 17:8-14. He R, Andonov A, Traykova-Adonova M, Cao J, Cutts T, Grudesky E, Deschambaul Y, Berry J, Drebot M, Li X. Potent and selective inhibition of SARS coronavirus replication by aurintricarboxylic acid. Biochem Biophys Res Commun. 2004 Aug 6;320(4):1199-203. He R, Dobie F, Ballantine M, Leeson A, Li Y, Bastien N, Cutts T, Andonov A, Cao J, Booth TF, Plummer FA, Tyler S, Baker L, Li X. (2004) Analysis of multimerization of the SARS coronavirus nucleocapsid protein. Biochem Biophys Res Commun. 2;316(2):476-83. He R, Leeson A, Ballantine M, Andonov A, Baker L, Dobie F, Li Y, Bastien N, Feldmann H, Ströher U, Theriault S, Cutts T, Cao J, Booth TF, Plummer FA, Tyler S, Li X (2004). Characterization of protein-protein interaction between the nucleocapsid protein and membrane protein of the SARS coronavirus. Virus Res. 105: 121-125. Hermann, L.L. and K.M. Coombs. (2004). Inhibition of reovirus by mycophenolic acid is associated with the M1 genome segment. J. Virol. 78:6171-6179. Hermann, L.L., and K.M. Coombs. (2004). Mycophenolic acid inhibits replication of Type 2 Winnipeg, a cerebrospinal fluid-derived reovirus isolate. Can. J. Inf. Dis. Med. Microbiol. 15:261-265. Hirst M, Astell CR, Griffith M, Coughlin SM, Moksa M, Zeng T, Smailus DE, Holt RA, Jones S, Marra MA, Petric M, Krajden M, Lawrence D, Mak A, Chow R, Skowronski DM, Tweed SA, Goh S, Brunham RC, Robinson J, Bowes V, Sojonky K, Byrne SK, Paetzel M, Li Y, Kobasa D, Booth T, and Paetzel M. (2004). A novel avian influenza H7N3 strain associated with an Avian Influenza Outbreak in British Columbia. Emerg Infect Dis. 10: 2192-2195. Hoebe CJ, de Melker H, Spanjaard L, Dankert J, Nagelkerke N. Space-time cluster analysis of invasive meningococcal disease. Emerg Infect Dis. 2004 Sep;10(9):1621-6. Hogan RJ, Gao G, Rowe T, Bell P, Flieder D, Paragas J, Kobinger GP, Wivel NA, Crystal RG, Boyer J, Feldmann H, Voss TG, Wilson JM (2004). Resolution of primary severe acute respiratory syndrome-associated cornovirus infection requires Stat1. J. Virol. 78: 11416-11421. Hogbom, M., Stenmark, P., McClarty, G. and Nordlund, P. 2004. The Chlamydia ribonucleotide reductase-a novel radical site in Class-I R2s. Science 305:245-248 Holbrook MR, Aronson JF, Campbell GA, Jones S, Feldmann H, Barrett AD (2004). An animal model for the tickborne flavivirus – Omsk hemorrhagic fever. J. Infect. Dis. 191: 100-108. Hombach-Klonisch S, Kehlen A, Fowler PA, Huppertz B, Jugert FK, Bischoff G, Schlüter E, Buchmann J, Klonisch T (2005) Regulation of functional steroid receptors and ligand-induced responses in telomerase-immortalized human endometrial epithelial cells (hTERT-EEC). J Mol Endocrinol 34: 517-534. Hombach-Klonisch S, Pocar P, Kietz S, Klonisch T (2005) Molecular actions of polyhalogenated arylhydrocarbons (PAHs) in female reproduction. Curr Med Chem, 12: 599-616. Hombach-Klonisch S, Schön J, Kehlen A, Blottner S, Klonisch T (2004) Seasonal expression of INSL3 and Lgr8/INSL3 receptor transcripts indicates variable differentiation of Leydig cells in the roe deer testis. Biol Reprod, 71:1079-1087. Hong Z, Smart G, Zaniewski G, Wu H, Wu J, Goedhuis N, Giulivi A, Kaita K and Dawood M. (2005) Epidemiological study of hepatitis B virus infection in Manitoba, Canada, 1992-2003. Eur J Clin Microbiol Infect Dis. 24: 464-470. Hook EW, Peeling RW. Syphilis control: a continuing challenge. N Eng J Med 351:122-124, 2004. Hooton TM, Besser R, Foxman B, Fritsche TR, Nicolle LE. Acute uncomplicated cystitis in an era of increasing antitiotic resistance: A proposed approach to empiric therapy. Clin Infect Dis 2004; 39:75-80. Hutchinson, J., W. Runge, M. R. Mulvey, G. Norris, M. Yetman, F. Lepine, N. Valkova. 2004. Burkholderia cepacia Infections Associated with Intrinsically Contaminated Ultrasound Gel - the Role of Microbial Degradation of Parabens. Infection Control and Hospital Epidemiology. 25:291-296. Infectious Diseases and Immunization Committee (Embree JE, Chair). Canadian Paediatric Society. Paediatric Infectious Disease Notes. Bag urine specimens still not appropriate in diagnosing urinary tract infections in infants. Paediatr Child Health 9:377-378, 2004 & Can J Infect Dis & Med Micro 15:, 2004. Infectious Diseases and Immunization Committee (Embree JE, Chair), Canadian Paediatric Society and The Committee on Pediatric AIDS, The American Academy of Pediatrics . 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