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“Create-A-Being” Grade Level: Science 10, Life Science (Genetics) Specific PLO Addressed: Apply the principles that govern the inheritance of traits to solve problems involving simple Mendelian genetics Class Time: 2 one-hour periods The original idea for this activity came from a seminar that was developed for elementary school classes, by the Eureka Science Camp team during the summer of 2001. I have simply adapted the seminar into an activity suitable for a science 10 class and created a ruberic by which the students’ work can be assessed. Preparation: This activity is designed as a summative exercise for the Science 10 Genetics unit. Prior to beginning this exercise the students should have acquired a solid understanding of Mendelian genetics, the use of punnet squares, and the differences between complete, incomplete and co-dominance. Timeline: Give the instructions and worksheets to the students the period before this project is to be begun. Inform the students that they can build their “being” in any way, using any materials they wish (within reason of course). If the students wish to construct a 3-d model of their “being” they should bring any materials they wish to use to the next class period. At the beginning of the next class period, hand out the parental information. Do NOT give the students their parental information until the beginning of the period in which they will work on the project. This way all students will be working on the same stage of the project at the same time. It will likely take most of the first class period for the students to complete the worksheets, and only at the very end of the period will the fastest students be ready to begin construction of their “being”. The next class period will be spent constructing, drawing, or somehow creating the “being”. This may be a good time to also use as review for the chapter test….students can approach and ask any questions they may have regarding the chapter while working on the project. Create-A-Being!! In this activity, you and a partner will be responsible for the creation of an entirely original “being”! In order to create this individual you will be required to draw upon your vast knowledge of genetics (that you acquired during your studies of Unit 1 so far), and will need to correctly complete a number of Punnett squares to decide which of a number of traits will be exhibited by your individual. After deciding upon what the exhibited traits will be, you must create your individual in any way you see fit. You will also be required to write a short report describing the various traits of your “being”, along with any extra interesting information. The following is a list of the possible traits your “being” may inherit and/or exhibit… Hair Colour Blonde bb Black BB Brown Bb Nose Shape Small/pointy ss Med./Bulbous Ss Lg/Beaky SS Ear Size Tiny tt Average Tt Large TT Earlobes Attached aa Unattached Aa, AA Body Shape Skinny rr Rounded Rr, RR Skin Colour Purple pp Blue PP Polka-Dotted Pp Limb Length Short ww Mixture Ww Long WW It is important to note that some of the above traits exhibit complete dominance, while others exhibit incomplete or co-dominance. Since all traits are inherited, it is vital to know both the pheno- and genotypes of the parents in order to calculate the possible pheno- and genotypes of the offspring. Each pair of students will be given a different set of parental information from which to construct their individual. All calculations should be performed on the following worksheets, and these worksheets must be handed in along with the written report and newly created “being” in order to receive marks for the activity. Create-A-Being!! Worksheets From the parental information you have been given, please complete the following Punnett square questions. You will receive 1 mark for each parental phenotype or genotype that you correctly interpret, 4 marks for each accurately completed Punnett square, and 2 marks for correctly identifying and pairing the offspring phenotypes and genotypes. “We received parental information sheet #_______” 1. Hair Colour – Incomplete Dominance Maternal Phenotype: _________ Maternal Genotype: ___________ Paternal Phenotype: _________ Paternal Genotype: ___________ Offspring Phenotypes & Genotypes: ___________________________ ___________________________ ___________________________ ___________________________ 2. Nose Shape – Incomplete Dominance Maternal Phenotype: _________ Maternal Genotype: ___________ Paternal Phenotype: _________ Paternal Genotype: ___________ Offspring Phenotypes & Genotypes: ___________________________ ___________________________ ___________________________ ___________________________ 3. Ear Size – Incomplete Dominance Maternal Phenotype: _________ Maternal Genotype: ___________ Paternal Phenotype: _________ Paternal Genotype: ___________ Offspring Phenotypes & Genotypes: ___________________________ ___________________________ ___________________________ ___________________________ 4. Earlobe Appearance – Complete Dominance Maternal Phenotype: _________ Maternal Genotype: ___________ Paternal Phenotype: _________ Paternal Genotype: ___________ Offspring Phenotypes & Genotypes: ___________________________ ___________________________ ___________________________ ___________________________ 5. Body Shape – Complete Dominance Maternal Phenotype: _________ Maternal Genotype: ___________ Paternal Phenotype: _________ Paternal Genotype: ___________ Offspring Phenotypes & Genotypes: ___________________________ ___________________________ ___________________________ ___________________________ 6. Skin Colour – Co-dominance Maternal Phenotype: _________ Maternal Genotype: ___________ Paternal Phenotype: _________ Paternal Genotype: ___________ Offspring Phenotypes & Genotypes: ___________________________ ___________________________ ___________________________ ___________________________ 7. Limb Length – Co-dominance Maternal Phenotype: _________ Maternal Genotype: ___________ Paternal Phenotype: _________ Paternal Genotype: ___________ Offspring Phenotypes & Genotypes: ___________________________ ___________________________ ___________________________ ___________________________ Now that you have discovered the possible genotypes and corresponding phenotypes…how to discover which ones your individual will exhibit? Calculate the probability of each genotype and phenotype, and assign the trait with the highest probability to your individual. In the case of equal probabilities, flip a coin to decide which trait will be exhibited. It is important to note that in reality it is not always the trait with the highest probability of being inherited that is inherited! List the traits that your individual will exhibit in the following table along with their probabilities. Trait Genotype Probability Hair Colour % Nose Shape % Ear Size % Earlobe Appearance % Body Shape Skin Colour % % Limb Length % Phenotype Create-A-Being!! Worksheets 1. Draw a picture of each parent creature you were assigned. 2. Draw a picture of the offspring that they created (use the traits you determined from your Punnett squares) 3. Does your offspring look identical to either of the parent creatures? 4. Which parent does your offspring more closely resemble? 5. Why do you think they more closely resemble that parent? (hint, think in terms of genotypes) Challenge Question: 6. Using all of the knowledge that you have gained from our study of genetics so far, explain HOW it is that 23 chromosomes inherited from each parent can result in an offspring that exhibits characteristics of both parents. Try to include as many of the following words as you can in your explanation: DNA, gene, mRNA, tRNA, transcription, translation, amino acid, protein, chromosomes, traits, dominant, recessive, complete dominance, incomplete dominance, codominance, inheritance Sample Parental Information Sheets Give a different information sheet to each group. Make sure the students know that each group is working with different information; this should hopefully eliminate copying between groups. Information Sheet #1 Mom Blonde hair, small/pointy nose, avg. ear size, attached earlobes, skinny, polka dotted skin colour, long limbs Dad Brown hair, large/beaky nose, large ears, heterozygous unattached earlobes, skinny purple body with short limbs. Information Sheet #2 Mom Black hair, small/pointy nose, large ear size, homozygous unattached earlobes, heterozygous rounded blue body with long limbs Dad Brown hair, medium/bulbous nose, small ears, attached earlobes, skinny polka dotted body with mixed-length limbs. Information Sheet #3 Mom Brown hair, large/beak-like nose, avg. ear size, attached earlobes, skinny, purple body with long limbs. Dad Blonde hair, small/pointy nose, large ears, homozygous unattached earlobes, homozygous round polka dotted body with short limbs. Information Sheet #4 Mom Blonde hair, med/bulbous nose, avg. ear size, heterozygous unattached earlobes, skinny, polka dotted skin colour, long limbs Dad Brown hair, large/beaky nose, large ears, attached earlobes, homozygous rounded purple body with short limbs. Information Sheet #5 Mom Black hair, small/pointy nose, tiny ear size, heterozygous unattached earlobes, heterozygous rounded blue body with long limbs Dad Blonde hair, medium/bulbous nose, tiny ears, attached earlobes, skinny polka dotted body with mixed-length limbs. Information Sheet #6 Mom Brown hair, large/beak-like nose, avg. ear size, attached earlobes, skinny, purple body with long limbs. Dad Blonde hair, small/pointy nose, tiny ears, homozygous unattached earlobes, heterozygous round polka dotted body with short limbs. Information Sheet #7 Mom Black hair, small/pointy nose, avg. ear size, attached earlobes, skinny, polka dotted skin colour, long limbs Dad Brown hair, large/beaky nose, large ears, heterozygous unattached earlobes, skinny purple body with short limbs. Information Sheet #8 Mom Blonde hair, small/pointy nose, large ear size, homozygous unattached earlobes, heterozygous rounded blue body with long limbs Dad Brown hair, medium/bulbous nose, tiny ears, attached earlobes, skinny polka dotted body with mixed-length limbs. Information Sheet #9 Mom Brown hair, large/beak-like nose, tiny ear size, attached earlobes, skinny, purple body with long limbs. Dad Blonde hair, small/pointy nose, average ears, homozygous unattached earlobes, homozygous round polka dotted body with short limbs. Information Sheet #10 Mom Blonde hair, med/bulbous nose, avg. ear size, heterozygous unattached earlobes, skinny, polka dotted skin colour, mixed-length limbs Dad Brown hair, large/beaky nose, large ears, attached earlobes, homozygous rounded purple body with short limbs. Information Sheet #11 Mom Black hair, small/pointy nose, tiny ear size, homozygous unattached earlobes, heterozygous rounded blue body with short limbs Dad Blonde hair, medium/bulbous nose, tiny ears, attached earlobes, skinny polka dotted body with mixed-length limbs. Information Sheet #12 Mom Brown hair, large/beak-like nose, avg. ear size, attached earlobes, skinny, purple body with long limbs. Dad Blonde hair, small/pointy nose, tiny ears, homozygous unattached earlobes, heterozygous round polka dotted body with short limbs.