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RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES KARNATAKA, BANGALOR ANNEXURE - II PERFORMA FOR REGISTRATION OF SUBJECTS FOR DISSERTATION 1. NAME OF THE MR. BHEEMANAGOUDA. D. PADEKANUR CANDIDATE AND I YEAR M Sc NURSING ADDRESS. BLDEA’S SHRI B. M. PATIL INSTITUTE OF NURSING SCIENCES BIJAPUR. 2. NAME OF THE BLDEA’S SHRI B. M. PATIL INSTITUTE OF INSTITUTION. NURSING SCIENCES BIJAPUR – 586103 3. 4. COURSE OF THE STUDY AND M Sc. NURSING SUBJECT. MEDICAL SURGICAL NURSING. DATE OF 28.07.2011 ADMISSION TO THE COURSE. 5 TITLE OF THE STUDY. "A STUDY TO EVALUATE THE EFFECTIVENESS OF SELF INSTRUCTIONAL MODULE ON KNOWLEDGE REGARDING AUTOLOGOUS BLOOD TRANSFUSION AMONG STAFF NURSES WORKING IN A SELECTED HOSPITAL AT BIJAPUR.” 1 6. BRIEF RESUME OF THE INTENDED WORK. Introduction. Health is greatest gift, contentment the greatest wealth, faithfulness the best relationship -Buddha Water and blood are the lifeline for the people only their colors differ. Millions of lives are saved across the world through the timely life saving blood transfusion procedures1. The first historical attempt of blood transfusion was described in 17th century before that in the year 1492 Pope innocent VIII sank into coma and blood of three boys was infused into the dying Pope through the mouth as the concept of circulation and methods of intravenous access did not exist at that time. However not only the pope died but three children did also died. And in the year 1667 Dr Jean Batiste transfused the blood of sheep into a 15 year old boy who survived after transfusion.2 The first successful human blood transfusion was done in 1818 by Dr James Blundell. From 18th century till today the life saving procedure and its span has enhanced for thousands of clients. Recently in the year 1980 a new technique was invented by British scientists that is autologous blood transfusion.3 Blood collected from a patient for re-transfusion at a later time into the same individual is called autologous blood. The patient who receives his or her own blood gets the safest possible blood, because no foreign antigens infused, no infectious diseases are transmitted. Its use has increased with the awareness of infections particularly human immune deficiency virus transmitted through allogenic transfusion.4 Allogenic blood on the other hand, is collected from someone other than the patient. Over the last several years an increased awareness of diseases transmitted by allogenic blood has resulted in a dramatic increase in autologous blood transfusion. Clinical research and practice in autologous blood use have also grown in recent years, providing new insights into the issues involved regarding autologous blood transfusion.5 2 Since most planned surgical procedures are associated with autologous blood transfusion like, coronary artery bypass, major vascular surgery, primary hip replacement, total knee replacement, major spine surgery with instrumentation, selected neurological procedures, hepatic resections, radical prostatectomy, cervical spine fusion, intervertebral discectomy, mastectomy, hysterectomy, reduction cholecystectomy, tonsillectomy, vaginal and cesarean deliveries and mammoplasty, transurethral resection of prostate6. The benefits of autologous blood transfusion are in contrast with donor blood, the patient’s type of blood is instantly available and requires no cross matching, no risk of transfusion reaction due to incomparability, no risk of transmitted disease such as among others HIV/AIDS, Hepatitis B and C and Syphilis7. The benefits of allogeneic and autologous RBC transfusions are similar, but the risks of autologous blood are less. Hence, the risk-benefit ratio supports the more liberal use of autologous blood.8 It is necessary that nurses should have adequate knowledge about autologous blood transfusion to avoid transfusion adverse effects. 6.1 Need for the study. Blood is the fragile scarlet tree, we carry within us - Osbert Blood transfusions are necessary for accident victims, surgical clients, clients with blood disorders, burns, malaria, severe blood loss as well as altered bone marrow function related to radiation therapy, chemotherapy and other medications to save their live. It is done to add more blood to the client’s blood stream. The amount of blood to be transferred depends on the amount of blood loss and the severity of blood disorder. All over the World millions of lives will be saved every day through blood transfusion. 9 Blood collected from a patient for re-transfusion at a later time into the same individual is called "autologous blood”.6 Advantages of autologous blood transfusion are preventing wrong blood to wrong patient and also that of transfusion-transmitted diseases, in this autologous blood transfusion high quality fully functional red cells reinfused,44.4% postoperative infection rate with allogenic blood vs 17.4% with autologous blood, shorter hospital stay, reduced cost of antibiotics and laboratory tests, donating blood promotes blood cell production by bone marrow.10 3 In this recent decade India is running short with the blood which requires to save the lives but at the same time a many priceless units of blood is imported from long distance each year to fill the needies. This estimation was proposed by nonprofit national blood resource centre. Over the last several years an increased awareness of diseases transmitted by allogenic blood has resulted in a dramatic increase in autologous blood transfusion .Approximately 16 million units are donated annually and of those about 6, 43, 000 are autologous .This number of autologous donations is growing each year. Clinical research and practice in autologous blood use have also grown in recent years, providing new insights into the issues involved.11 More than three million blood components are transfused every year in the U.K providing life saving and life is enhancing treatment to thousands of clients. However, transfusion error, resulting in the client receiving the incorrect blood component, remains the largest risk related to transfusion in the U.K. By developing accessible blood transfusion policies, auditable performance standards, training and educational initiatives, nurses can increase compliance in high risk areas of the transfusion process and reduce the potential for errors .This review recommended that there is need to create awareness regarding autologous blood transfusion among the staff nurses.12 Developing a quality autologous blood recovery program is a team effort. Members of transfusion committees, hospital blood bank personnel, or staff members of the surgery committee are all possible sources of information. Local blood center also may have literature or services that could be of assistance knowledge of current autologous transfusion alternatives will help nurses communicate with patients regarding transfusion therapy and will make nurses more valuable participants in the crucial decisions necessary to deliver optimal patient care in perioperative period.13 A study was conducted to assess the knowledge and practice of many hospital staff, including doctors, nurses, and pharmacists etc. In Japan, which are engaged in blood transfusion services. The study concluded that there is a great need for special education in transfusion medicine.14 A survey was conducted to assess the knowledge and to evaluate the practice on autologous blood transfusion among nurses. First survey revealed poor practice and knowledge among nurses and a training programme was implemented. After two years 4 2nd survey was conducted which consisted of four questions identical to first survey in order to assess the impact of training strategy. The four questions were on blood samples identification, patient identification and pre transfusion bed side compatibility test. The results showed the improvement in knowledge and practice about autologous blood transfusion between the first and second survey.15 Nurses will play a significant role in identification of transfusion risks such as transmission of serious blood borne infections and potentially fatal immunologic and non-immunologic reactions. So, they need to have a thorough knowledge on pathophysiology of transfusion reactions, presenting symptoms and treatment necessary to monitor transfusion safety. Through meticulous nursing assessment, detection and proper planning of intervention, nurses can prevent and minimize morbidity and mortality in clients receiving autologous blood transfusion. The staff nurses will be rendering the services in varied settings. They have to possess adequate knowledge, skills, and specialized training in transfusion Medicine to improve the quality of comprehensive nursing care. Hence, the investigator felt the need to assess the effectiveness of self instructional module on autologous blood transfusion among staff nurses working in a selected hospital at Bijapur. 6.2 Review of Literature. A review article on blood management in orthopedic surgery discusses the different options for blood salvage. States that filtering alone does not markedly reduce cytokine concentrations in the processed blood. The cost-effectiveness of using washed blood is questioned since it requires an expensive device and technical expertise to operate it and may thus be too costly to recommend as a standard procedure.. The use of unwashed blood, on the other hand, is considered cost-effective in decreasing the need for allogeneic blood transfusion. Review was recommended that there is a need for educational intervention regarding autologous blood transfusion.16 A cross sectional study was conducted to assess the awareness and perceptions of health care providers regarding autologous blood safety and blood donation. Samples included doctors, trainee doctors, nurses and technicians. A stratified random sampling technique was used for this study. A pre designed and pre tested semi structured questionnaire was used to collect data. The results shown that 69.7% of health care 5 providers knew correctly, about blood safety and 70.7% were not aware of autologous blood donation. There is a need of creating awareness regarding autologous blood transfusion.17 A descriptive study was conducted assessment of knowledge on importance of autologous blood transfusion. A group of 50 pre university students was selected for the study by using a purposive sampling method. A descriptive survey approach was used. A semi-structured questionnaire was used to assess the knowledge level of trained nurses regarding body mechanics. The study reveals that, among 50 students, 21 (42%) students have adequate knowledge; 12 (24%) have moderate knowledge and 17 (34%) have inadequate knowledge regarding importance of autologous blood transfusion. There is a need of further research studies to educate needy group18 A survey was conducted among physicians and nurses to determine their overall knowledge about autologous blood transfusions. The physician questionnaire was a 12question survey. The questions focused on informed consent and transfusion-related risks that the committee felt every physician would know. A similar test, 14 questions developed by the Nursing Education Department, was administered to nursing staff and focused on basic transfusion techniques and practices. Both groups scored significantly lower (in the 50%–80% range) than anticipated (in the 85%–100% range). Following an educational process, a repeat survey demonstrated significant improvement in all areas. This indicated that the importance of providing a constant source of information and feedback to all staff involved in transfusion services. There is a need of educational intervention regarding autologous blood transfusion.19 A study was conducted to evaluate the significance of autologous blood transfusion (AT) in reducing homologous blood transfusion (HT) in surgery for hepatocellular carcinoma (HCC) and also investigated the impact of AT and HT on longterm postoperative outcome after curative surgery for HCC. Result was the proportion of patients with HT was significantly lower in period B than period A (18.9% vs 60.2%, P < 0.0001). Multivariate logistic regression analysis identified AT administration as a significant independent predictor of the need for HT (P < 0.0001). Disease-free survival in patients with AT was comparable to that without any transfusion. Multivariate analysis identified HT administration as an independent significant factor for poorer disease-free survival (P = 0.0380). The study concluded that AT administration 6 significantly decreased the need for HT. Considering the postoperative survival disadvantage of HT, AT administration could improve the long-term outcome of HCC patients.20 The retrospective study was under took to determine the effect of autologous blood transfusion on the incidence of adverse postoperative events in patients undergoing major amputation. The demographic variables, need for autologous blood transfusion, and clinical outcomes were recorded. The impact of autologous blood transfusion on clinical outcome was analyzed. Of the 300 patients undergoing major amputation, 191 (64%) had one or more blood transfusions. Patients undergoing blood transfusion were 2.5 times more likely to suffer from a postoperative cardiac arrhythmia, 12.8 times more likely to develop acute renal failure, 5.7 times more likely to have pneumonia, and 2.2 times more likely to have a urinary tract infection.21 A study was conducted on the perception of risk associated with autologous blood donation and transfusion including the use of so-called blood substitutes. A questionnaire survey was conducted involving 88 general practitioners, 143 anesthetists’, 20 journalists, and 250 nursing students. Respondents were asked through free response questions to identify the risks they most associated with blood transfusion and the infections associated with autologous blood transfusion and donation. They were also asked to indicate their preference for their own blood, compared to donor blood or a blood substitute. The percentage of respondents who preferred to receive their own blood, compared to donor blood or a suitable substitute, was 73–94%. When required to choose between donor blood or a blood substitute, there were significant (P < 0.05) differences between sample groups: anesthetists and GPs preferred to receive a blood substitute (52–59%), whereas nursing students and journalists preferred donated blood (74–93%). These findings have clear implications for the future development and implementation of modern transfusion options, including the use and acceptability of blood substitutes as alternatives to donor blood.22 The study was conducted to evaluate the effectiveness of a self-instructional module in increasing nurses' knowledge of genetics. Pretest/post-test study design was used. 262 registered nurses involved in screening egg donors at 177 reproductive health centers. Sixty-five registered nurses were working at reproductive health centers. 100 of 262 eligible nurses completed the pretest (38% return rate) and 65 of these 100 nurses also completed the post-test (65% retention rate). Results revealed that there was a 7 significant increase in mean knowledge score of 20.8% on the post-test (89.0% mean, SD=8%, range=67-100%) as compared to the pretest (69.0% mean, SD=12%, range=4292%), based on paired t test analysis (t=11.74, SE=0.426, p< .0001). Thus more in depth independent study programs in genetics for nurses are recommended.23 A study was conducted on need based preparation and evaluation of self instructional module for staff nurses on care of a child receiving oxygen therapy. The study aimed at finding association between learning needs and selected variables and determining validity of self instructional module, on “care of a child receiving oxygen therapy” and evaluating the effectiveness of the self instructional module. A survey approach was used for phase one and one group pretest posttest design was adopted for phase two. The total sample of the study was 30 staff nurses, of 6 months experience in pediatric ward. The study concludes that self instructional module was effective in terms of gain in knowledge score as well as acceptability and utility scores of staff nurses.24 6.3 Problem statement. A study to evaluate the effectiveness of self instructional module on knowledge regarding autologous blood transfusion among staff nurses working in a selected hospital at Bijapur. 6.4 Objectives. 1. To assess the level of knowledge regarding autologous blood transfusion among staff nurses as measured by structured knowledge questionnaire. 2. To find out the effectiveness of self instructional module regarding autologous blood transfusion among staff nurses. 3. To find the association between the pre-test knowledge regarding autologous blood transfusion with selected socio demographic variables. 6.5 Operational definitions. 1. Effectiveness: It refers to determine the extent to which the self instructional module programme achieved the desired effect in improving the knowledge of staff nurses regarding autologous blood transfusion. 8 2. Self instructional module: It refers to a written material prepared by the investigator includes, introduction, definition, types, and its advantages, procedure of autologous blood transfusion. 3. Knowledge: In this study knowledge refers to awareness of staff nurses regarding meaning and concept, indications, incidence, methods, management and complications of autologous blood transfusion. 4. Autologous blood transfusion: In this study autologous blood transfusion refers to collection and reinfusion of the patients own blood or blood components. 5. Staff nurses : In this study staff nurses refer to the registered nurses working in a selected hospital at Bijapur. 6.6 Assumptions. 1. Staff nurses may have inadequate knowledge regarding autologous blood transfusion. 2. Administration of self instructional module will help to enhance the knowledge of staff nurses regarding autologous blood transfusion. 6.7 Hypothesis. The following hypotheses will be tested at 0.05 level of significance. H1- There is a significant difference between pre test and post test knowledge. H2- There is a significant association between pretest knowledge score with selected demographic variables. 6.8 Delimitation. 1. This study is limited to staff nurses working in selected hospitals at Bijapur. 2. This study is delimited to 60 staff nurses. 3. The study is limited to only knowledge about autologous blood transfusion. 4. The study is limited to only selected hospital at Bijapur. 9 7. MATERIALS AND METHODS 7.1 Source of data collection. Staff nurses working in a selected hospital at Bijapur. 7.1.1 Research Design. In this study research design is pre-experimental research design. (one group pre test post test experimental design) 7.1.2 Research Approach. Evaluative research approach. 7.1.3 Setting The study will be conducted in a selected hospital at Bijapur. 7.1.4 Population. Registered staff nurses who are working in selected hospital at Bijapur. 7.1.5 Variables. 1. Independent variable. Self instructional module 2. Dependant variable Knowledge of staff nurses regarding autologous blood transfusion. 7.2 Method of data collection 7.2.1 Sampling. The sampling procedure will be purposive sampling technique. 10 7.2.2 Sample size. In this study sample size will be 60 registered staff nurses from selected hospital at Bijapur. 7.2.3 Inclusion criteria for sampling. 1. Staff nurses from selected hospitals. 2. Staff nurses who are available during time of study. 3. Staff nurses who are willing to participate in study. 7.2.4 Exclusion criteria for sampling. 1. Staff nurses who are not registered in state nursing council. 2. Staff nurses who are undergone training of transfusion medicine. 7.2.5 Instruments to be used. 1. Section A – Includes selected socio demographic variables. 2. Section B- Structured knowledge questionnaire. 7.2.5 Data collection method. 1. Permission will be obtained from the concerned authority. 2. Purpose of conducting the study will be explained to the subjects. 3. Informed consent will be obtained from the subjects. 4. Data will be collected using structured knowledge questionnaire. 7.2.7 Data analysis plan. 7.2.8 Data will be analyzed according to the objectives and hypotheses of the study, using descriptive statistics like mean, median, frequency, and percentage. Inferential statistics like chi square test, paired T test, standard deviation, cumulative percentage and Data will be presented in the form of tables, graphs and diagrams. 11 7.2.8 Duration of the study : 4 - 6 weeks 7.3 Does the study require any investigation to be conducted on patients or other human or animals (if so please describe briefly) NO. 7.4 Has ethical clearance been obtained from your institution in case of 7.3? Not applicable. 12 8 LIST OF REFERENCES. 1) Biradar V. Autologous blood transfusion Nightingales nursing times 2010; 6(2):57-62. 2) Blood and Blood Transfusion Available from:URL:http://www.blood transfusion Wikipedia 3) Autologous blood transfusion Available from: URL:http://www.edurite.com.htm: 4) Available from: URL:http://www.wisegeek.com. 5) Benjamin Lichtiger, MD, Yango Huch MD, Current issues in transfusion medicine 1992, October-December. 6) Autologous blood transfusion Available from :URL:http//www.blood index.com 7) Henry DA et al Pre-operative autologous donation for minimizing perioperative allogenic blood transfusion Cochrane review issue 2003 January. 8) Vanderlinde, Elizabeth S. Joanna M Heal, and Neil Blunberg Autologous blood transfusion, British medical Journal 2002 march, 324:722-5. 9) Available from : URL:http//www.Blood transfusion.com 10) The serious Hazards of Transfusion annual report 2007 Ref: http//www.shotuk.org/home.htm. 11) Available from: http//www.globalbloodstatistics.com. 12) Based on WHO Global Database on blood safety and blood safety indicators. Available from: http//www.globalbloodbank.com. 13) Johnson GM, Bowman RJ American Red cross. Autologous blood transfusion. Current trends, nursing implications. American Red cross AORN J 1992 Aug, 56(2):282-92. 14) Dr. Mohd. Samiullah khan .Paramedical and nursing Times Hyderabad Magnum Graphics.2005. 13 15) Available from: http//[email protected]. 16) Keating EM, 1998: Current options and approaches for blood management in orthopedic surgery J Bone joint surg 80-A: 5,750-62. 17) Available from: http//www.bloodBook.com. 18) Available from: http//www.globalbloodstatistics.com. 19) Available from: http//www.tralispain.com. 20) Yoshito tomimaru, Hidetoshi. Eguchi, Shigeru et al department of surgery Graduate school of medicine Osaka university2-2 Yamadaoka, Suita 565-0871, Osaka Japan Advantage of autologous blood transfusion in surgery for hepatocellular carcinoma. 21) Sail our Glens son F, Tricaud S, mathoulin-Peliser S, Bouchon B, Galperine I, Failon P. Factors associated with nurse’s poor knowledge and practice of Transfusion Safety procedure. Int J Quail Health care. 2009:14(1) .25-32. 22) Umar AS, Abdulkareem “A Cross sectional study was conducted to assess the awareness and perceptions of health care providers regarding blood safety and blood transfusion” 2007. 23) Swank, Colleen O'Donnell; effectiveness of a genetics self-instructional module for nurses involved in egg donor screening; 2001 Nov-Dec; 30(6); Pg-617-25. 24) Machado A, Bhaduri A, George A; oxygen therapy for children; need based preparation and evaluation of self instructional module for staff nurses on care of a child receiving oxygen therapy; 1998 Jun; 89(6); Pg- 125-27. 14 15