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著作類別 著作名稱 PMID 論文 Journal Paper Tseng TH,Chien MH,Lin WL,Wen YC,Chow JM,Chen CK, Kuo TC, Lee WJ. Inhibition of MDA-MB-231 breast cancer cell proliferation and tumor growth by apigenin through induction of G2/M arrest and histone H3 acetylation-mediated p21WAF1/CIP1 expression. . Environ Toxicol. .2017 ;(32):434-444 26872304 論文 Journal Paper Chang JL,Chow JM,Chang JH,Wen YC,Lin YW,Yang SF, Lee WJ, Chien MH. Quercetin simultaneously induces G0/G1-phase arrest and caspase-mediated crosstalk between apoptosis and autophagy in human leukemia HL-60 cells . Environ Toxicol. .2017 28251795 論文 Journal Paper Lin YW,Lee LM,Lee WJ,Chu CY,Tan P,Yang YC, Chen WY, Yang SF, Hsiao M, Chien MH. Melatonin inhibits MMP-9 transactivation and renal cell carcinoma metastasis by suppressing Akt-MAPKs pathway and 26732239 NF-κB-DNA-binding activity. . J Pineal Res. .2016 ;(60):277-290 論文 Journal Paper Kao SJ,Lee WJ,Chang JH,Chow JM,Chung CL,Hung WY, Chien MH. Suppression of reactive oxygen species-mediated ERK and JNK activation sensitizes dihydromyricetin-induced mitochondrial apoptosis in human non-small cell lung cancer. . Environ Toxicol. .2016 ;(32):1426-1438 論文 Journal Paper Chen WY,Hua KT,Lee WJ,Lin YW,Liu YN,Chen CL, Wen YC, Chien MH. Akt Activation Correlates with Snail Expression and Potentially Determines the Recurrence of Prostate Cancer in Patients at Stage T2 after a 27455254 Radical Prostatectomy. . Int J Mol Sci. .2016 ;(17):E1194 論文 Journal Paper Lin CW,Yang WE,Lee WJ,Hua KT,Hsieh FK,Hsiao M, Chen CC, Chow JM, Chen MK, Yang SF, Chien MH. Lipocalin 2 prevents oral cancer metastasis through carbonic anhydrase IX inhibition and is associated with 27207653 favourable prognosis. . Carcinogenesis .2016 ;(37):712-722 論文 Journal Paper Kuo TC,Chen CK,Hua KT,Yu P,Lee WJ,Chen MW, Jeng YM, Chien MH, Kuo KT, Hsiao M, Kuo ML. Glutaminase 2 stabilizes Dicer to repress Snail and metastasis in hepatocellular carcinoma cells. . Cancer Lett. 27725225 .2016 ;(383):282-294 論文 Journal Paper Chien MH,Lee TH,Lee WJ,Yeh YH,Li TK,Wang PC, Chen JJ, Chow JM, Lin YW, Hsiao M, Wang SW, Hua KT. Trichodermin induces c-Jun N-terminal kinase-dependent apoptosis caused by mitotic arrest and DNA 27965041 damage in human p53-mutated pancreatic cancer cells and xenografts. . Cancer Lett. .2016 ;(388):249-261 論文 Journal Paper Lee WJ,Hsiao M,Chang JL,Yang SF,Tseng TH,Cheng CW, Chow JM, Lin KH, Lin YW, Liu CC, Lee LM, Chien MH. Quercetin induces mitochondrial-derived apoptosis via reactive oxygen species-mediated ERK activation in HL-60 leukemia cells and xenograft. . Arch Toxicol. .2015 ;(89):1103-1117 論文 Journal Paper Yang SF,Lee WJ,Tan P,Tang CH,Hsiao M,Hsieh FK, Chien MH. MiR-328 upregulation and CREB-DNAbinding activity inhibition are critical for resveratrol-mediated suppression of matrix metalloproteinase-2 and 25605016 subsequent metastatic ability in human osteosarcomas. . Oncotarget .2015 ;(6):2736-2753 論文 Journal Paper Lin FY,Lin CW,Yang SF,Lee WJ,Lin YW,Lee LM, Chang JL, Weng WC, Lin CH, Chien MH. Interactions between environmental factors and melatonin receptor type 1A polymorphism in relation to oral cancer susceptibility and clinicopathologic development. . PLoS One. .2015 ;(10):e01216 25806809 論文 Journal Paper Lee WJ,Chien MH,Chow JM,Chang JL,Wen YC,Lin YW, Hsiao M, Lee LM. Nonautophagic cytoplasmic vacuolation death induction in human PC-3M prostate cancer by curcumin through reactive oxygen species mediated endoplasmic reticulum stress. . Sci Rep. .2015 ;(5):10420 26013662 論文 Journal Paper Chao R,Chow JM,Hsieh YH,Chen CK,Lee WJ,Hsieh FK, Yu NY, Chou MC, Cheng CW, Yang SF, Chien MH. Tricetin suppresses the migration/invasion of human glioblastoma multiforme cells by inhibiting matrix 26245494 metalloproteinase-2 through modulation of the expression and transcriptional activity of specificity protein 1. . Expert Opin Ther Targets. .2015 ;(19):1293-1306 論文 Journal Paper Chien MH,Lee WJ,Hsieh FK,Li CF,Cheng TY,Wang MY, Chen JS, Chow JM, Jan YH, Hsiao M, Hua KT, Kuo ML. Keap1-Nrf2 interaction suppresses cell motility in lung adenocarcinomas by targeting the S100P protein. . Clinical Cancer Research .2015 ;(21):4719-4732 26078391 論文 Journal Paper Wu MH,Lee WJ,Hua KT,Kuo ML,Lin MT. Macrophage Infiltration Induces Gastric Cancer Invasiveness by Activating the β-Catenin Pathway. . PLoS One. .2015 ;(10):e01341 26226629 論文 Journal Paper Chang JS,Su CY,Yu WH,Lee WJ,Liu YP,Lai TC, Jan YH, Yang YF, Shen CN, Shew JY, Lu J, Yang CJ, Huang MS, Lu PJ, Lin YF, Kuo ML, Hua KT, H. GIT1 promotes lung cancer cell metastasis through modulating Rac1/Cdc42 activity and is associated with poor prognosis. . Oncotarget .2015 ;(6):36278-36291 26462147 論文 Journal Paper Wen YC,Lee WJ,Tan P,Yang SF,Hsiao M,Lee LM, Chien MH. By inhibiting snail signaling and miR-23a-3p, osthole suppresses the EMT-mediated metastatic ability in prostate cancer. . Oncotarget .2015 ;(6):2112026110567 21136 27539140 25138434 論文 Journal Paper Chen CK,Yang CY,Hua KT,Ho MC,Johansson G,Jeng YM, Chen CN, Chen MW, Lee WJ, Su JL, Lai TC, Chou CC, Ho BC, Chang CF, Lee PH, Chang KJ, Hsiao. Leukocyte cell-derived chemotaxin 2 antagonizes MET receptor activation to suppress hepatocellular carcinoma vascular invasion by protein tyrosine phosphatase 1B recruitment. . Hepatology .2014 ;(59):974-985 24114941 論文 Journal Paper Hua KT,Lee WJ,Yang SF,Chen CK,Hsiao M,Ku CC, Wei LH, Kuo ML, Chien MH. Vascular endothelial growth factor-C modulates proliferation and chemoresistance in acute myeloid leukemic cells through an endothelin-1-dependent induction of cyclooxygenase-2. . Biochimica et Biophysica Acta (BBA) - Molecular Cell Research .2014 ;(1843):387-397 24184161 論文 Journal Paper Shen KH,Liao AC,Hung JH,Lee WJ,Hu KC,Lin PT, Liao RF, Chen PS. α-Solanine inhibits invasion of human prostate cancer cell by suppressing epithelial-mesenchymal transition and MMPs expression. . Molecules. 25116803 .2014 ;(19):11896-11914 論文 Journal Paper Wen YC,Chen WY,Lee WJ,Yang SF,Lee LM,Chien MH. Snail as a potential marker for predicting the recurrence of prostate cancer in patients at stage T2 after radical prostatectomy. . Clin Chim Acta. .2014 ;(431):169-173 論文 Journal Paper Tung MC,Hsieh MJ,Wang SS,Yang SF,Chen SS,Wang SW, Lee LM, Lee WJ, Chien MH. Associations of VEGF-C Genetic Polymorphisms with Urothelial Cell Carcinoma Susceptibility Differ between Smokers and 24608123 Non-Smokers in Taiwan. . PLoS One. .2014 ;(9):e91147 論文 Journal Paper Hsiao PC,Chou YE,Tan P,Lee WJ,Yang SF,Chow JM, Chen HY, Lin CH, Lee LM. Pterostilbene simultaneously induced G0/G1-phase arrest and MAPK-mediated mitochondrial-derived apoptosis in human acute myeloid leukemia cell lines. . PLoS One. .2014 ;(9):e10534 25144448 論文 Journal Paper Hsiao PC,Lee WJ,Yang SF,Tan P,Chen HY,Lee LM, Chang JL, Lai GM, Chow JM, Chien MH. Nobiletin suppresses the proliferation and induces apoptosis involving MAPKs and caspase-8/-9/-3 signals in human acute myeloid leukemia cells. . Tumour Biol. .2014 ;(35):11903-11911 25164609 論文 Journal Paper Kuo TC,Tan CT,Chang YW,Hong CC,Lee WJ,Chen MW, Jeng YM, Chiou J, Yu P, Chen PS, Wang MY, Hsiao M, Su JL, Kuo ML. Angiopoietin-like protein 1 suppresses SLUG to inhibit cancer cell motility. . J Clin 23434592 Invest. .2013 ;(123):1082-1095 論文 Journal Paper Lin CW,Chuang CY,Tang CH,Chang JL,Lee LM,Lee WJ, Chow JM, Yang SF, Chien MH. Combined effects of icam-1 single-nucleotide polymorphisms and environmental carcinogens on oral cancer susceptibility and 24069166 clinicopathologic development. . PLoS One. .2013 ;(8):e72940 論文 Journal Paper Liao AH,Li YK,Lee WJ,Wu MF,Liu HL,Kuo ML. Estimating the delivery efficiency in cancer cells of drugloaded microbubbles with US and BLI . Ultrasound in Medicine and Biology .2012 ;(38):1938-1948 論文 Journal Paper Lee WJ,Chen YR,Tseng TH. Quercetin induces FasL-related apoptosis, in part, through promotion of histone 21165570 H3 acetylation in human leukemia HL-60 cells. . Oncol Rep .2011 ;(25):583-591 論文 Journal Paper Hua KT,Tan CT,Johansson G,Lee JM,Yang PW,Lu HY, Su JL, Chen PB, Wu YL, Chi CC, Kao HJ, Shih HJ, Chen MW, Chien MH, Chen PS, Lee WJ, Cheng TY,. Naa10p suppresses cancer cell metastasis by binding to 21295525 PIX/Cool proteins and inhibiting Cdc42/Rac1 activity. . Cancer Cell. .2011 ;(19):218-231 論文 Journal Paper Lee WJ,Lu FJ,Wang SF,Chen YR,Tseng TH. In vitro enhancement effect of humic acid on the progression of 19686714 lung cancer cells. . Chem Biol Interact. .2009 ;(181):463-471 論文 Journal Paper Lee WJ,Chen WK,Wang CJ,Lin WL,Tseng TH. Apigenin inhibits HGF-promoted invasive growth and metastasis involving blocking PI3K/Akt pathway and beta 4 integrin function in MDA-MB-231 breast cancer 17961621 cells. . Toxicol Appl Pharmacol. .2008 ;(226):178-191 論文 Journal Paper Lee WJ,Wu LF,Chen WK,Wang CJ,Tseng TH. Inhibitory effect of luteolin on hepatocyte growth factor/scatter factor-induced HepG2 cellinvasion involving both MAPK/ERKs and PI3K-Akt pathways. . Chem Biol Interact. .2006 ;(160):123-133 16458870 論文 Journal Paper Lu FJ,Tseng TH,Lee WJ,Yen CC,Yin YF,Liao CW, Liu KM. Promoting neoplastic transformation of humic acid in mouse epidermal JB6 Cl41 cells. . Chem Biol Interact. .2006 ;(162):249-258 16939684 24513541 22929655