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NOTES: Respiratory System (UNIT 7-part 2) – Breathing Mechanism *Changes in the size of the thoracic cavity accompany INSPIRATION and EXPIRATION. INSPIRATION = EXPIRATION = *ATMOSPHERIC PRESSURE (760 mmHg; the “weight” of the air) is the force that moves air into the lungs. *Air (gases) move from regions of to regions of INSPIRATION: • if the pressure inside the lungs/alveoli decreases, atmospheric pressure will force air into the lungs How does the pressure inside the lungs decrease??? > Diaphragm contracts ( ) > Thoracic cage moves upward and outward ( the ) of the thoracic cavity causes a • as the walls of the thoracic cavity expand, they pull on the parietal pleura (758 mmHg) • the serous fluid in the pleural cavity holds the pleural membranes tightly together (much like a wet microscope slide will stick to another microscope slide) • as the parietal pleura is pulled outward, the visceral pleura follows… • _____!! **for a deeper breath, the diaphragm and intercostals muscles contract with more force EXPIRATION: • the forces for normal exhalation come from of tissues • the opposite pressure and volume changes occur…pressure inside the lungs increases and forces air out How does the pressure inside the lungs increase??? > Diaphragm relaxes (moves upward) > External intercostals muscles relax; thoracic cage moves downward and inward Lungs and thoracic cage recoil and return to their original shape the of the thoracic cavity causes an !! (763 mmHg) RESPIRATORY AIR VOLUMES AND CAPACITIES: • one = one inspiration followed by one expiration • the amt. of air that moves in (or out) during a single respiratory cycle is the -about 500mL _ • even after forceful expiration, some air remains in the lungs ( )…why? -so that lungs don’t collapse! (alveoli always stay partially inflated) -prevents the O2 and CO2 levels from fluctuating greatly (“new” air always mixes with “old” air) • the maximum amt. of air a person can exhale after taking the deepest possible breath is the (4600 mL) TOTAL LUNG CAPACITY = VITAL CAPACITY + RESIDUAL VOLUME **all of these volumes/capacities vary with (average is about 5800mL) Control of Breathing / Gas Exchange and Transport *Normal breathing is rhythmic and involuntary. Respiratory Center: ● the respiratory center is in the brain stem (pons and medulla) FACTORS AFFECTING BREATHING: 1) respiratory center in the brain 2) chemical concentrations (gases, ions, pH, etc.) 3) stretching of lung tissue 4) emotional state EXAMPLES: *when chemoreceptors in the walls of certain large arteries detect low O2 levels (or high CO2 levels), breathing rate increases *fear and pain typically increase the normal breathing pattern ALVEOLAR GAS EXCHANGES * occurs in the alveoli. ● ALVEOLI: tiny air sacs in the lungs clustered at the ends of alveolar ducts ● Gases (O2 and CO2) diffuse from regions of partial pressure) to regions of ● OXYGEN diffuses from ● CARBON DIOXIDE diffuses from (and (partial pressure) into into GAS TRANSPORT IN THE BLOOD / BODY *Blood transports gases between the lungs and body cells. OXYGEN TRANSPORT: ● oxygen binds to the protein in the blood (inside RBC’s) ● the resulting molecule, ______________________________, is unstable and readily releases oxygen in regions where oxygen concentration (partial pressure of oxygen aka: PO2) is low ● more oxygen will be released from oxyhemoglobin when: -CO2 levels in the blood increase which causes _______________________________________ CARBON DIOXIDE TRANSPORT: ● carbon dioxide may be carried: **as a bicarbonate ion (HCO3-); MOST CO2 is in this form! - (different spot on molecule than where oxygen binds) ● carbon dioxide reacts with water to form carbonic acid ● carbonic acid dissociates to release hydrogen ions and bicarbonate ions: H+ lowers pH of blood and changes the shape of hemoglobin so that oxygen is released