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Figure 18.1a Generalized structure of arteries, veins, and capillaries.
Artery
Vein
© 2014 Pearson Education, Inc.
Figure 18.1b Generalized structure of arteries, veins, and capillaries.
Tunica intima
• Endothelium
• Subendothelial layer
• Internal elastic membrane
Tunica media
(smooth muscle and
elastic fibers)
• External elastic membrane
Tunica externa
(collagen fibers)
• Vasa vasorum
Artery
Vein
Valve
Capillary
network
Lumen
Capillary
© 2014 Pearson Education, Inc.
Lumen
Basement membrane
Endothelial cells
Figure 18.2 The relationship of blood vessels to each other and to lymphatic vessels.
Venous system Arterial system
Large veins
(capacitance
vessels)
Small veins
(capacitance
vessels)
Heart
Large
lymphatic
vessels
Elastic
arteries
(conducting
arteries)
Lymph
node
Lymphatic
system
Muscular
arteries
(distributing
arteries)
Arteriovenous
anastomosis
Lymphatic
capillaries
Sinusoid
Postcapillary
venule
Thoroughfare Capillaries Precapillary
(exchange sphincter
channel
© 2014 Pearson Education, Inc.
vessels)
Arterioles
(resistance
vessels)
Terminal
arteriole
Metarteriole
Figure 18.3a Capillary structure.
Pericyte
Red blood
cell in lumen
Intercellular
cleft
Endothelial
cell
Basement
membrane
Tight junction
Endothelial
nucleus
Pinocytotic
vesicles
Continuous capillary. Least permeable, and most
common (e.g., skin, muscle).
© 2014 Pearson Education, Inc.
Figure 18.3b Capillary structure.
Pinocytotic
vesicles
Red blood
cell in lumen
Fenestrations
(pores)
Endothelial
nucleus
Basement membrane
Tight junction
Intercellular
cleft
Endothelial
cell
Fenestrated capillary. Large fenestrations (pores)
increase permeability. Occurs in areas of active
absorption or filtration (e.g., kidney, small intestine).
© 2014 Pearson Education, Inc.
Figure 18.3c Capillary structure.
Endothelial
cell
Red blood
cell in lumen
Large
intercellular
cleft
Tight junction
Incomplete
basement
membrane
Nucleus of
endothelial
cell
Sinusoid capillary. Most permeable. Occurs in special
locations (e.g., liver, bone marrow, spleen).
© 2014 Pearson Education, Inc.
Figure 18.4 Anatomy of a capillary bed.
Vascular shunt
Precapillary sphincters
Metarteriole
Thoroughfare
channel
True
capillaries
Terminal arteriole
Postcapillary venule
Sphincters open—blood flows through true capillaries.
Terminal arteriole
Postcapillary venule
Sphincters closed—blood flows through metarteriole – thoroughfare
channel and bypasses true capillaries.
© 2014 Pearson Education, Inc.
Figure 18.5 Relative proportion of blood volume throughout the cardiovascular system.
Pulmonary blood
vessels 12%
Systemic arteries
and arterioles 15%
Heart 8%
Capillaries 5%
Systemic veins
and venules 60%
© 2014 Pearson Education, Inc.
Figure 18.7 The muscular pump.
Venous valve (open)
Contracted skeletal
muscle
Venous valve
(closed)
Vein
Direction of blood flow
© 2014 Pearson Education, Inc.
Closer Look Box Figure UN01
© 2017 Pearson Education, Inc.
Closer Look Box Figure UN02
© 2017 Pearson Education, Inc.
Figure 18.20 Schematic flowchart showing an overview of the systemic circulation.
Common carotid
arteries to head
and subclavian
arteries to
upper limbs
Capillary beds of
head and
upper limbs
Superior
vena cava
Aortic
arch
Aorta
RA
LA
RV
Azygos
system
Venous
drainage
Inferior
vena
cava
LV
Thoracic
aorta
Arterial
blood
Capillary beds of
mediastinal structures
and thorax walls
Diaphragm
Abdominal
aorta
Inferior
vena
cava
Capillary beds of
digestive viscera,
spleen, pancreas,
kidneys
Capillary beds of gonads,
pelvis, and lower limbs
© 2017 Pearson Education, Inc.
Figure 18.21a Major arteries of the systemic circulation.
R. external
carotid artery
R. common carotid
– right side of head and neck
R. vertebral
R. axillary
R. internal
carotid artery
R. subclavian
– neck and
R. upper limb
Brachiocephalic
– head, neck, and
R. upper limb
Arteries of
R. upper
limb
L. external
carotid artery
L. internal
carotid artery
L. common carotid
– left side of head and neck
Aortic arch
L. vertebral
L. subclavian
– neck and L.
upper limb
L. axillary
Arteries of
L. upper
limb
Ascending aorta
– L. ventricle to sternal angle
Thoracic aorta T5–T12 (diaphragm)
L. and R. coronary
arteries
L. ventricle of heart
Visceral branches
Mediastinal
– posterior
mediastinum
Esophageal
– esophagus
Bronchial
– lungs and
bronchi
Parietal branches
Pericardial
– pericardium
Posterior intercostals
– intercostal muscles, spinal
cord, vertebrae, pleurae, skin
Superior phrenics
– posterior and superior
diaphragm
Diaphragm
Abdominal aorta T12 (diaphragm)–L4
Parietal branches
Visceral branches
Gonadal
– testes or
ovaries
Suprarenal
– adrenal
glands
and
Renal
– kidneys
Superior
and inferior
mesenterics
– small
intestine
– colon
Celiac trunk
– liver
– gallbladder
– spleen
– stomach
– esophagus
– duodenum
R. common iliac
– pelvis and R. lower limb
Arteries of R. lower limb
Schematic flowchart
© 2017 Pearson Education, Inc.
Inferior phrenics
– inferior diaphragm
Lumbars
– posterior
abdominal
wall
Median sacral
– sacrum
– coccyx
L. common iliac
– pelvis and L. lower limb
Arteries of L. lower limb
Figure 18.21b Major arteries of the systemic circulation.
Arteries of the head and trunk
Internal carotid artery
External carotid artery
Common carotid arteries
Vertebral artery
Subclavian artery
Brachiocephalic trunk
Aortic arch
Ascending aorta
Arteries that supply the upper limb
Subclavian artery
Axillary artery
Coronary artery
Celiac trunk
Brachial artery
Abdominal aorta
Superior mesenteric artery
Renal artery
Gonadal artery
Inferior mesenteric artery
Radial artery
Ulnar artery
Common iliac artery
Internal iliac artery
Deep palmar arch
Superficial palmar arch
Digital arteries
Arteries that supply the lower limb
External iliac artery
Femoral artery
Popliteal artery
Anterior tibial artery
Posterior tibial artery
Arcuate artery
Illustration, anterior view
© 2017 Pearson Education, Inc.
Figure 18.22a Arteries of the head, neck, and brain.
R. and L. anterior
cerebral arteries
R. Middle
cerebral
artery
Anterior
communicating
artery
Cerebral arterial circle
Ophthalmic
artery
Superficial
temporal
artery
R. and L.
posterior
communicating
arteries
R. Posterior
cerebral
artery
Basilar
artery
R. and L.
vertebral
arteries
Maxillary
artery
Occipital
artery
R. and L.
internal
carotid
arteries
Facial
artery
Lingual
artery
R. and L.
external
carotid
arteries
Superior
thyroid
artery
R. and L.
common
carotid
arteries
R. and L.
subclavian
arteries
Brachiocephalic trunk
Aortic arch
(a) Schematic flowchart
© 2017 Pearson Education, Inc.
Figure 18.22b-d Arteries of the head, neck, and brain.
Ophthalmic artery
Basilar artery
Vertebral
artery
Internal
carotid artery
Branches of
the external
carotid artery
• Superficial
temporal artery
• Maxillary artery
• Occipital artery
External
carotid artery
Common
carotid artery
• Facial artery
• Lingual artery
• Superior thyroid
artery
Thyrocervical
trunk
Larynx
Costocervical
trunk
Thyroid gland
(overlying trachea)
Subclavian
artery
Clavicle (cut)
Axillary
artery
Brachiocephalic
trunk
Internal thoracic
artery
Anterior
Arteries of the head and neck, right aspect
Cerebral arterial
circle
(circle of Willis)
Frontal lobe
Optic chiasma
• Anterior
communicating
artery
Middle
cerebral
artery
• Anterior
cerebral artery
Internal
carotid
artery
• Posterior
communicating
artery
Mammillary
body
• Posterior
cerebral artery
Temporal
lobe
Basilar artery
Vertebral artery
Pons
Occipital lobe
Cerebellum
Posterior
Colorized arteriograph of the arterial
supply of the brain
© 2017 Pearson Education, Inc.
Major arteries serving the brain (inferior view, right side
of cerebellum and part of right temporal lobe removed)
Figure 18.22b Arteries of the head, neck, and brain.
Ophthalmic artery
Basilar artery
Vertebral
artery
Internal
carotid artery
External
carotid artery
Common
carotid artery
Branches of
the external
carotid artery
• Superficial
temporal artery
• Maxillary artery
• Occipital artery
• Facial artery
• Lingual artery
• Superior thyroid
artery
Thyrocervical
trunk
Larynx
Costocervical
trunk
Thyroid gland
(overlying trachea)
Subclavian
artery
Clavicle (cut)
Axillary
artery
Arteries of the head and neck, right aspect
© 2017 Pearson Education, Inc.
Brachiocephalic
trunk
Internal thoracic
artery
Figure 18.22c Arteries of the head, neck, and brain.
Colorized arteriograph of the arterial
supply of the brain
© 2017 Pearson Education, Inc.
Figure 18.22d Arteries of the head, neck, and brain.
Anterior
Cerebral arterial
circle
(circle of Willis)
Frontal lobe
Optic chiasma
• Anterior
communicating
artery
Middle
cerebral
artery
• Anterior
cerebral artery
Internal
carotid
artery
• Posterior
communicating
artery
Mammillary
body
• Posterior
cerebral artery
Temporal
lobe
Basilar artery
Vertebral artery
Pons
Occipital lobe
Cerebellum
Posterior
Major arteries serving the brain (inferior view, right side
of cerebellum and part of right temporal lobe removed)
© 2017 Pearson Education, Inc.
Figure 18.23a Arteries of the right upper limb and thorax.
R. common
carotid
artery
R. vertebral artery
L. common carotid
artery
L. vertebral artery
Thyrocervical trunk
Suprascapular artery
L. subclavian
artery
R. subclavian artery
Axillary artery
Thoracoacromial
artery
Thoracoacromial
artery
(pectoral
branch
Anterior
and posterior
circumflex
humeral
arteries
Brachial
artery
Deep
artery
of arm
Aortic arch
Brachiocephalic
trunk
Internal
thoracic
artery
Anterior
intercostal
arteries
Lateral
thoracic
artery
Subscapular
artery
Anastomosis
Common
interosseous
artery
Radial
artery
Deep
palmar
arch
Ulnar artery
Metacarpal arteries
Superficial palmar arch
Digital arteries
Schematic flowchart
© 2017 Pearson Education, Inc.
Costocervical
trunk
Thoracic
aorta
Posterior
intercostal
arteries
Figure 18.23b Arteries of the right upper limb and thorax.
Vertebral artery
Common carotid arteries
Thyrocervical trunk
Right subclavian artery
Costocervical trunk
Left subclavian artery
Suprascapular artery
Thoracoacromial artery
Brachiocephalic trunk
Axillary artery
Subscapular artery
Posterior intercostal
arteries
Posterior circumflex
humeral artery
Anterior circumflex
humeral artery
Anterior intercostal artery
Brachial artery
Internal thoracic artery
Lateral thoracic artery
Deep artery of arm
Descending aorta
Common interosseous
artery
Radial artery
Ulnar artery
Deep palmar arch
Superficial palmar arch
Digital arteries
Illustration, anterior view
© 2017 Pearson Education, Inc.
Figure 18.24a Arteries of the abdomen.
Diaphragm
Abdominal
aorta
Inferior
phrenic
arteries
L. gastric artery
R. gastric
artery
Common
hepatic
artery
Hepatic
artery
proper
L
Celiac
trunk
Splenic
artery
Gastroduodenal R
artery
R. gastroepiploic
artery
Middle
suprarenal
arteries
L. gastroepiploic artery
Intestinal arteries
Middle colic
artery
Superior
mesenteric
artery
R. colic
artery
Renal
arteries
Ileocolic artery
Gonadal
arteries
Sigmoidal
arteries
Inferior
mesenteric
artery
L. colic
artery
Lumbar
arteries
Superior rectal
artery
Median sacral artery
Common iliac arteries
Schematic flowchart.
© 2017 Pearson Education, Inc.
Figure 18.24b Arteries of the abdomen.
Liver (cut)
Inferior vena cava
Diaphragm
Esophagus
Celiac trunk
Left gastric artery
Common hepatic artery
Stomach
Hepatic artery proper
Gastroduodenal artery
Splenic artery
Right gastric artery
Left gastroepiploic
artery
Gallbladder
Spleen
Pancreas
(major portion lies
posterior to stomach)
Right gastroepiploic
artery
Duodenum
Abdominal aorta
Superior mesenteric
artery
The celiac trunk and its major branches. The left half of the liver has been removed.
© 2017 Pearson Education, Inc.
Figure 18.24c Arteries of the abdomen.
Hiatus (opening)
for inferior vena cava
Diaphragm
Hiatus (opening)
for esophagus
Inferior phrenic artery
Adrenal (suprarenal)
gland
Middle suprarenal artery
Celiac trunk
Renal artery
Kidney
Superior mesenteric
artery
Abdominal aorta
Lumbar arteries
Gonadal (testicular
or ovarian) artery
Ureter
Inferior mesenteric artery
Median sacral
artery
Common iliac artery
Major branches of the abdominal aorta.
© 2017 Pearson Education, Inc.
Figure 18.24d Arteries of the abdomen.
Celiac trunk
Superior mesenteric
artery
Transverse colon
Aorta
Branches of the superior
mesenteric artery
• Middle colic artery
• Intestinal arteries
• Right colic artery
• Ileocolic artery
Ascending colon
Right common iliac artery
Ileum
Inferior mesenteric
artery
Branches of the inferior
mesenteric artery
• Left colic artery
• Sigmoidal arteries
• Superior rectal artery
Descending colon
Cecum
Appendix
Sigmoid colon
Rectum
Distribution of the superior and inferior mesenteric arteries. The transverse colon has
been pulled superiorly.
© 2017 Pearson Education, Inc.
Figure 18.25a Arteries of the right pelvis and lower limb.
Abdominal
aorta
Superior
gluteal
artery
Internal
iliac
artery
Inferior gluteal
artery
Internal pudendal
Deep
artery
of thigh
Medial circumflex
femoral artery
Lateral
circumflex
femoral
artery
Common
iliac
artery
Obturator
artery
External
iliac artery
Femoral
artery
Adductor
hiatus
Arterial
anastomosis
Popliteal
artery
Anterior
tibial
artery
Posterior tibial
artery
Fibular (peroneal)
artery
Dorsalis
pedis artery
Lateral plantar
artery
Lateral plantar
artery
Medial plantar
artery
Arcuate
artery
Plantar arch
Dorsal metatarsal
arteries
Plantar metatarsal
arteries
Schematic flowchart
© 2017 Pearson Education, Inc.
Figure 18.25b Arteries of the right pelvis and lower limb.
Common iliac artery
Internal iliac artery
Superior gluteal artery
External iliac artery
Deep artery of thigh
Lateral circumflex
femoral artery
Medial circumflex
femoral artery
Obturator artery
Femoral artery
Adductor hiatus
Popliteal artery
Anterior tibial artery
Posterior tibial artery
Fibular artery
Dorsalis pedis artery
Arcuate artery
Dorsal metatarsal
arteries
Anterior view
© 2017 Pearson Education, Inc.
Figure 18.25c Arteries of the right pelvis and lower limb.
Popliteal artery
Anterior tibial artery
Posterior tibial
artery
Lateral plantar
artery
Medial plantar
artery
Posterior view
© 2017 Pearson Education, Inc.
Fibular
artery
Dorsalis pedis
artery (from top
of foot)
Plantar
arch
Figure 18.26a Major veins of the systemic circulation.
Veins of
R. upper
limb
R. axillary
R. vertebral
– cervical spinal
cord and
vertebrae
R. external
jugular
– superficial
head and neck
Intracranial
dural venous sinuses
R. internal jugular
– dural venous
sinuses of the brain
R. subclavian
– R. head, neck,
and upper
limb
Same as R. brachiocephalic
R. brachiocephalic
– R. side of head and R. upper limb
L. brachiocephalic
– L. side of head and L. upper limb
Superior vena cava
– runs from union of brachiocephalic
veins behind manubrium to R. atrium
Azygos system
– drains much of
thorax
R. atrium of heart
Diaphragm
Inferior vena cava
– runs from junction of common iliac
veins at L5 to R. atrium of heart
R. suprarenal
(L. suprarenal drains
into L. renal vein)
– adrenal glands
R. gonadal
(L. gonadal drains
into L. renal vein)
– testis or ovary
R. common iliac
– pelvis and R. lower
limb
Veins of
R. lower limb
Schematic flowchart
© 2017 Pearson Education, Inc.
L., R., and middle
hepatic veins
– liver
L. and R. renal veins
– kidneys
Lumbar veins
(several pairs)
– posterior abdominal
wall
L. common iliac
– pelvis and L. lower
limb
Veins of
L. lower limb
Figure 18.26b Major veins of the systemic circulation.
Veins of the head and trunk
Dural venous sinuses
External jugular vein
Vertebral vein
Internal jugular vein
Veins that drain
the upper limb
Right and left
brachiocephalic veins
Subclavian vein
Superior vena cava
Cephalic vein
Great cardiac vein
Axillary vein
Brachial vein
Basilic vein
Hepatic veins
Splenic vein
Hepatic portal vein
Renal vein
Superior mesenteric vein
Inferior mesenteric vein
Inferior vena cava
Median cubital vein
Ulnar vein
Radial vein
Common iliac vein
Internal iliac vein
Digital veins
Veins that drain the lower limb
External iliac vein
Femoral vein
Great saphenous vein
Popliteal vein
Posterior tibial vein
Anterior tibial vein
Small saphenous vein
Dorsal venous arch
Dorsal metatarsal veins
Illustration, anterior view. The vessels of the pulmonary circulation are not shown.
© 2017 Pearson Education, Inc.
Figure 18.27a Venous drainage of the head, neck, and brain.
Superior sagittal
sinus
Inferior
sagittal sinus
Occipital
vein
Superficial
temporal vein
Ophthalmic
vein
Straight
sinus
Transverse
sinus
Cavernous
sinus
Facial vein
Posterior auricular
vein
Sigmoid sinus
Internal jugular vein
External jugular
vein
Superior thyroid vein
Vertebral vein
Middle thyroid vein
Brachiocephalic veins
Subclavian vein
Superior vena cava
Schematic flowchart
© 2017 Pearson Education, Inc.
Figure 18.27b Venous drainage of the head, neck, and brain.
Ophthalmic vein
Superficial temporal
vein
Facial vein
Occipital vein
Posterior
auricular vein
External
jugular vein
Vertebral vein
Internal
jugular vein
Superior and middle
thyroid veins
Brachiocephalic
vein
Subclavian vein
Superior
vena cava
Veins of the head and neck, right superficial aspect
© 2017 Pearson Education, Inc.
Figure 18.27c Venous drainage of the head, neck, and brain.
Superior sagittal sinus
Falx cerebri
Inferior sagittal sinus
Straight sinus
Cavernous sinus
Transverse sinuses
Sigmoid sinus
Jugular foramen
Right internal jugular vein
Dural venous sinuses of the brain
© 2017 Pearson Education, Inc.
Figure 18.28a Veins of the thorax and right upper limb.
Subclavian
Internal
vein
jugular vein
External
Brachiocephalic
jugular vein
veins
Axillary
vein
Superior
vena cava
Accessory
hemiazygos
vein
Median
cubital
vein
Azygos
vein
Brachial
vein
Hemiazygos
vein
Right and left posterior
intercostal veins
Cephalic
vein
Median
antebrachial
vein
Radial
vein
Basilic
vein
Ulnar
vein
Deep venous
palmar arch
Metacarpal veins
Superficial venous
palmar arch
Digital veins
Schematic flowchart
© 2017 Pearson Education, Inc.
Figure 18.28b Veins of the thorax and right upper limb.
Brachiocephalic veins
Internal jugular vein
Right subclavian vein
External jugular vein
Left subclavian vein
Axillary vein
Superior vena cava
Brachial vein
Azygos vein
Cephalic vein
Accessory hemiazygos vein
Basilic vein
Hemiazygos vein
Posterior intercostals
Inferior vena cava
Median cubital
vein
Ascending lumbar vein
Median
antebrachial
vein
Cephalic vein
Radial vein
Basilic vein
Ulnar vein
Deep venous
palmar arch
Superficial venous
palmar arch
Digital veins
Anterior view
© 2017 Pearson Education, Inc.
Figure 18.29a Veins of the abdomen.
Inferior
vena cava
Cystic vein
Hepatic
portal
system
Inferior phrenic veins
Hepatic veins
Hepatic portal vein
Superior mesenteric vein
Splenic vein
Suprarenal
veins
Renal veins
Inferior
mesenteric
vein
Gonadal veins
Lumbar
veins
R. ascending
lumbar vein
Common iliac
veins
L. ascending
lumbar vein
External iliac vein
Internal iliac veins
Schematic flowchart.
© 2017 Pearson Education, Inc.
Figure 18.29b Veins of the abdomen.
Inferior phrenic vein
Hepatic veins
Inferior vena cava
Right suprarenal
vein
Left suprarenal vein
Renal veins
Right gonadal
vein
Left ascending
lumbar vein
Lumbar veins
Left gonadal vein
Common iliac vein
External iliac vein
Internal iliac vein
Tributaries of the inferior vena cava. Venous drainage of abdominal organs not drained
by the hepatic portal vein.
© 2017 Pearson Education, Inc.
Figure 18.29c Veins of the abdomen.
Hepatic
veins
Inferior vena cava
Gastric veins
Liver
Spleen
Hepatic
portal
vein
Splenic vein
Right
gastroepiploic vein
Inferior
mesenteric vein
Small
intestine
Rectum
The hepatic portal circulation.
© 2017 Pearson Education, Inc.
Superior
mesenteric vein
Large intestine
Figure 18.30a Veins of the right lower limb.
Internal
iliac
vein
Inferior
vena cava
Common iliac vein
External iliac vein
Femoral
vein
Femoral
vein
Popliteal
vein
Small
saphenous
vein
Small
saphenous
vein
Anterior
tibial
vein
Fibular
(peroneal)
vein
Fibular
(peroneal)
vein
Posterior
tibial
vein
Plantar
veins
Dorsalis
pedis
vein
Dorsal venous
arch
Dorsal
metatarsal
veins
Great
saphenous
vein
Deep plantar arch
Digital veins
Anterior
Posterior
Schematic flowchart of the anterior and posterior veins
© 2017 Pearson Education, Inc.
Figure 18.30b-c Veins of the right lower limb.
Common iliac vein
Internal iliac vein
External iliac vein
Inguinal ligament
Femoral vein
Great saphenous
vein (superficial)
Popliteal vein
Small
saphenous
vein
Popliteal vein
Fibular vein
Fibular vein
Anterior
tibial vein
Small saphenous
vein (superficial)
Dorsalis
pedis vein
Anterior tibial vein
Posterior
tibial vein
Dorsal venous
arch
Dorsal
metatarsal
veins
Anterior view
© 2017 Pearson Education, Inc.
Great saphenous
vein
Plantar veins
Deep plantar arch
Digital veins
Posterior view
Figure 18.30b Veins of the right lower limb.
Common iliac vein
Internal iliac vein
External iliac vein
Inguinal ligament
Femoral vein
Great saphenous
vein (superficial)
Popliteal vein
Small
saphenous
vein
Fibular vein
Anterior
tibial vein
Dorsalis
pedis vein
Dorsal venous
arch
Dorsal
metatarsal
veins
Anterior view
© 2017 Pearson Education, Inc.
Figure 18.30c Veins of the right lower limb.
Great saphenous
vein
Popliteal vein
Anterior tibial vein
Fibular vein
Small saphenous
vein (superficial)
Posterior
tibial vein
Plantar veins
Deep plantar arch
Digital veins
Posterior view
© 2017 Pearson Education, Inc.