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BRIEF CURRICULUM VITAE
Surname: PISTOS
Name: CONSTANTINOS
Father’s name: MICHAEL
Date of Birth: 19-04-1970
Position at N.K.U.A: LABORATORY OF FORENSIC MEDICINE AND
TOXICOLOGY, SCHOOL OF MEDICINE
Rank: ASSISTANT PROFESSOR
Specification: Toxicology
Telephone numbers: 210-7462433 (Laboratory)
210-6729337 (Home)
6977409800 (Office)
e-mail: [email protected]
Academic Degrees-Professional Experience:

B.Sc. in Pharmacy, Department of Pharmacy, Aristotle University of
Thessaloniki (1995)

M.Sc. in Pharmaceutical Analysis-Quality Control (1998)

Ph.D. in Pharmaceutical Analysis-Quality Control (2001)

Post doctoral fellowship in Pharmaceutical Analysis in U.S.A. (The
University of Georgia Athens, U.S.A.) (2002)

Director of ILS bioanalytical laboratory for pharmacokinetic studies and
bioequivalence studies of pharmaceutical products (2006)

Lecturer of Toxicology (2006-2012)

Assistant Professor of Toxicology (2012-Today)
Teaching experience:
 During the academic years 1999-2001 and 2003-04, taught of
pharmacology, clinical pharmacology and cosmetology courses at the
private college Ι.Ι.Ε.Κ. Σ.Β.Ι.Ε.
 Since 2006:
1. Courses of Toxicology (Forensic, Clinical, Environmental and
Industrial) at Pharmacy and Medicine students.
2. Course of “Drufs of Abuse” at Medicine students.
3. Post-graduate courses of Toxicology at graduate students of
Pharmacy, Medicine and Biology.
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Publications:
 Publication of 36 scientific articles in foreign scientific journals
 Presentation of 20 scientific works at Greek and International scientific
congresses.
 Publication of 2 chapters of Toxicological interest in International
books.
MEMBER IN LOCAL AND INTERNATIONAL SCIENTIFIC GROUPS
 The International Association of Forensic Toxicologists (TIAFT)
 International Association of Therapeutic Drug Monitoring and Clinical
Toxicology (IATDMCT)
 Greek Association of Toxicology
 Greek Association of Pharmacist
Publications
1.
A fully validated method for the simultaneous determination of 11
antidepressant drugs in whole blood by gas chromatography-mass
spectrometry
I. Papoutsis, A. Khraiwesh, P. Nikolaou, C. Pistos, Ch. Spiliopoulou, S.
Athanaselis
J. Pharm. Biomed. Anal., 70, 557-562, 2012
2.
Direct urine analysis for the identification and quantification of selected
benzodiazepines for toxicology screening
S. Karampela, I. Vardakou, I. Papoutsis, A. Dona, Ch. Spiliopoulou, S.
Athanaselis, C. Pistos
J. Chromatogr. B, 902, 42-46, 2012
3.
A validated GC-MS method for the determination of Δ 9tetrahydrocannabinol and 11-nor-Δ 9-tetrahydrocannabinol-9- carboxylic acid
in bile samples
I. Papoutsis, A. Khraiwesh, P. Nikolaou, C. Pistos, Ch. Spiliopoulou, S.
Athanaselis
For. Toxicol. 30 (1), 51-58, 2012
4.
Naphyrone: a "legal high" not legal any more
Vardakou I., C. Pistos, A. Dona, Ch. Spiliopoulou, S. Athanaselis
Drug and Chemical toxicology, 35(4), 467-71, 2012
5.
Migration study of 1,3 butadiene in eye drops solutions
Pistos C., Karampela S., Vardakou I, Papoutsis I., Spiliopoulou Ch.,
Athanaselis S.
Drugs and Chem. Toxicol. 35(3), 293-9, 2012
6.
Development and validation of a simple GC-MS method for the
simultaneous determination of 11 anticholinesterase pesticides in blood Clinical and Forensic Toxicology applications
I. Papoutsis, M. Mendonis, P. Nikolaou, S. Athanaselis, C. Pistos, C.
Maravelias, Ch. Spiliopoulou
J Forensic Sci., 57(3), 806-12, 2012
7.
Carbon monoxide - related deaths in Greece: a 23-year survey
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M. Stefanidou, S. Athanaselis, A. Dona, C. Pistos, Ch. Spiliopoulou, C.
Maravelias
Am J Forensic Med. Pathol., 33(2), 128-31, 2012
8.
Development and validation of a method for the determination of
buprenorphine and norbuprenorphine in breast milk by gas chromatography–
mass spectrometry
P. Nikolaou, I. Papoutsis, S. Athanaselis, C. Pistos, A. Dona, Ch. Spiliopoulou
Biomed. Chromatogr. 26(3), 358-62, 2012
9.
A simple and sensitive GC/MS method for the determination of atropine
during therapy of anticholinesterase poisoning in serum samples
Papoutsis I., P. Nikolaou, Ch. Spiliopoulou, C. Pistos, M. Stefanidou, S.
Athanaselis.
Drug Test Anal. 4(3-4):229-34, 2012
10.
Development and validation of an EI-GC/MS method for the
determination of sertraline and its major metabolite desmethyl-sertraline in
blood
Khraiwesh A, Papoutsis I, Nikolaou P, Pistos C, Spiliopoulou C, Athanaselis
S.
J Chromatogr B Analyt Technol Biomed Life Sci., 879(25), 2576-82, 2011
11.
Development and validation of a gas chromatography-mass
spectrometric method for the determination of sildenafil and desmethylsildenafil in whole blood Papoutsis I., P. Nikolaou, S. Athanaselis, G.
Alevizopoulos, C. Pistos, Ch. Paraskevopoulou, Ch. Spiliopoulou
J Sep Sci., 34(21):3037-42, 2011.
12.
Development and validation of a GC/MS method for the determination
of tadalafil in whole blood
J. Pharm. Biomed. Anal. 56 (3), 577-581, 2011
P. Nikolaou, I. Papoutsis, S. Athanaselis, G. Alevizopoulos, A. Khraiwesh, C.
Pistos, Ch. Spiliopoulou
13.
Drugs for youth via internet and the example of mephedrone
Vardakou I, Pistos C, Spiliopoulou Ch.
Toxicol Lett. 201, 191-195, 2011
14.
A fully validated method for the determination of vardenafil in blood,
using gas chromatography/mass spectrometry
Papoutsis I, Nikolaou P, Athanaselis S, Pistos C, Maravelias C, Spiliopoulou
C.
J. Mass Spectrom. 23,71-76, 2011
15.
Development and validation of a highly sensitive GC/MS method for
the determination of buprenorphine and nor-buprenorphine in blood
Papoutsis I, Nikolaou P., Athanaselis S., Pistos C., Spiliopoulou Ch.,
Maravelias C.
J. Pharm. Biomed. Anal., 54 (3), 588-591, 2011
16.
Validated GC/MS method for the simultaneous determination of
clozapine and norclozapine in human plasma. Application in psychiatric
patients under clozapine treatment
Vardakou I, Dona A, Pistos C, Alevisopoulos G, Athanaselis S, Maravelias C,
Spiliopoulou C.
Journal of Chromatography B, 878 (25), 2327-2332, 2010
17.
Spice drugs as a new trend: mode of action, identification and
legislation
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Vardakou I, Pistos C, Spiliopoulou Ch.
Toxicol. Lett., 197 (3), 157-162, 2010
18.
Development and validation of an EI-GC-MS method for the
determination of benzodiazepine drugs and their metabolites in blood:
Applications in clinical and forensic toxicology
Papoutsis I., Athanaselis S., Nikolaou P., Pistos C., Spiliopoulou C.,
Maravelias C.
J. Pharm. Biomed. Anal., 52 (4), 609-614, 2010
19.
Mass intoxication with datura innoxia-case series and confirmation by
analytical toxicology
Papoutsis I., Nikolaou P., Athanaselis S., Stefanidou M., Pistos C.,
Spiliopoulou C., Maravelias C.
Clin. Tox., 48 (2), 143-145, 2010
20.
Investigation of the identification point system adaptation in cocaine,
benzoylecgonine and ecgonine methyl ester using a single quadrupole mass
spectrometer
Pistos C., Karampela S., Papoutsis I., Athanaselis S., Spiliopoulou Ch.,
Maravelias C.
rapid comm. mass spec., 23 (23), 3772-3780, 2009
21.
Development and validation of an EI-GC-MS method for the
determination of Methadone and its major metabolites (EDDP and EMDP) in
human breast milk
P. Nikolaou, I. Papoutsis, C. Maravelias, Ch Spiliopoulou, C. Pistos, A.
Calokerinos, J. Atta-Politou
J. Anal. Tox., 32, 478-484, 2008
22.
Off-line HPLC method combined to LC-MS for the determination of
sildenafil and its active metabolite in post-mortem human blood according to
confirmation criteria
Pistos C., Papoutsis I., Dona A., Stefanidou M., Athanselis S., Maravelias C.,
Spiliopoulou C.
Forensic Sci. Int. 4, 178 (2-3):192-8, 2008
23.
Application of the ion pair concept to the n-octanol-water partitioning of
cefepime and cefpirome
S.-A.Koufopoulou, C. Pistos, C. Giaginis, A. Tsantili-Kakoulidou
Inter. J. of Pharm., 316, 52-57, 2006
24.
Investigation of the retention/pH profile of zwitterionic fluoroquinolones
in
reversed-phase
and
ion-interaction
high
performance
liquid
chromatography
C. Pistos, M. Koupparis, A. Tsantili-Kakoulidou
J. Pharm Biomed. Anal., 39 (3-4), 438-443, 2005
25.
Liquid chromatographic tandem mass spectrometric determination of
trandolapril in human plasma
Constantinos Pistos, Maria Koutsopoulou, Irene Panderi.
Anal. Chim. Acta, 540 (2), 375-382, 2005
26.
Improved liquid chromatographic tandem mass spectrometric
determination and pharmacokinetic study of glimepiride in human plasma
C. Pistos, M. Koutsopoulou, I. Panderi-research article
Biomed. Chromatogr., 19 (5), 394-401, 2005
27.
Bioequivalence evaluation of two brands of glimepiride 4 mg tablets in
healthy human volunteers
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C. Pistos, M. Kalovidouris, C. Astraka, G. Kontopoulos and M. Koutsopoulou
Inter. J. of Clin. Pharm. and Therap., 43 (4), 203-208, 2004
28.
Assay of the simultaneous determination of acetaminophen-caffeinebutalbital in serum using a monolithic column
C. Pistos and James T. Stewart
J. Pharm Biomed. Anal, 36 (4), 737-741, 2004
29.
Liquid chromatography-positive ion electrospray mass spectrometry
method for the quantification of citalopram in human plasma
C. Pistos, J. Atta-Politou, I. Panderi
J. Chromatogr. B, 810 (2), 237-246, 2004
30.
Bioequivalence evaluation of two brands of Cefuroxime axetil 250mg
tablets in healthy human volunteers
C. Pistos, M. Kalovidouris, S. Michalea, G. Kontopoulos and M. Georgarakis
Inter. J. of Clin. Pharm. and Therap., 42 (7), 367-372, 2004
31.
Α Validated liquid chromatography-tandem mass spectrometry method
for the determination of mirtazapine and demethylmirtazapine in human
plasma: application to a pharmacokinetic study
C. Pistos, M. Koutsopoulou, I. Panderi
Anal. Chim. Acta, 514 (1), 15-26, 2004
32.
Direct injection HPLC method for the determination of selected
benzodiazepines in plasma using a Hisep column
C. Pistos and James T. Stewart
J. Pharm Biomed. Anal., 33 (5), 1135-1142, 2003
33.
Direct injection HPLC method for the determination of selected
phenothiazines in plasma using a Hisep column
C. Pistos, James T. Stewart
Biomed. Chromatogr., 17 (7), 465-470, 2003
34.
Rapid method for analysis of aspirin-butalbital in serum utilizing a
monolithic column
C. Pistos and J. T. Stewart
J. Liq. Chromatogr., 26 (15), 2567-2579, 2003
35.
The effect of ion pairing reagents in the retention profile of zwitterionic
cephalosporines
C. Pistos, A. Tsantili-Kakoulidou and M. Koupparis
J. Liq. Chromatogr, 26 (6), 937-952, 2003
36.
Determination of ethylenediamine tetra acetic acid in injective solution
of paracetamol by ion pair chromatography
C. Pistos and M. Parisi-Poulou
J. Pharm. Biomed. Anal., 28 (6), 1073-1079, 2002
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