Download BDS Ist YEAR EXAMINATION 2008-09

MBBS I (First) Professional Examination 2013-14
Course Code: MBS103
Paper ID: 0322242
Biochemistry -II
Time: 2 Hours 40 Minutes
Max Marks: 40
Note: Attempt all questions. Draw proper diagrams to support
your answer.
Part ‘B’
1.
What are fat-soluble vitamins? Describe in detail the
chemistry, biochemical functions, dietary requirements and
deficiency manifestations of vitamin A. Add a note on
hypervitaminosis A.
(1+7+2)
2. a)
b)
Describe the biochemical functions and deficiency
manifestations of sodium and potassium.
(5)
Describe the renal regulation of blood pH.
(5)
Write short notes on the following:
Thyroid function tests
Protein energy malnutrition (PEM)
Detoxification of Benzoic acid
Radioimmunoassay (RIA)
(2.5x4=10)
a)
b)
c)
d)
Write short notes on the following:
Proto-oncogenes
BMR and its influencing factors
Mismatch DNA repair system
Renal function Test
(2.5x4=10)
a)
b)
c)
d)
3.
4.
(10)
MBBS I (First) Professional Examination 2013-14
Roll No.
Student’s Name
Student’s Signature
Invigilator’s Signature
Course Code: MBS103
Paper ID: 0322242
Biochemistry - II
Part ‘A’
Time: 20 Minutes
Max Marks: 10
Note: 1. Attempt all questions and return this part of the question paper to the invigilator after 20 Minutes.
2. Please tick (√) correct one only. Cutting, overwriting or any other marking are not allowed.
3. For answering please use Ball- pen only.
Q.1
Q.2
Q.3
Q.4
Q.5
A strict vegetarian who does not consume
any animal product may develop the
deficiency of:
a)
Vitamin B1
b)
Vitamin C
c)
Vitamin B6
d)
Viatmin B12
Which one of the following vitamins does
not participate as coenzyme in the oxidative
decarboxylation of pyruvic acid:
a.
Thiamine
b.
Biotin
c.
Niacin
d.
Riboflavin
Which one of the following nutrients does
have the highest SDA?
a)
Carbohydrates
b)
Fats
c)
Proteins
d)
Vitamins
Hypoalbuminemia is seen in:
a)
Liver cirrhosis
b)
Marasmus
c)
Albinism
d)
Non of above
Which one of the following substances
increases the absorption of iron from
intestine:
a)
b)
c)
d)
Q.6
Q.7
Cysteine
Tyrosine
Glycine
Glutamine
Serum alkaline phosphatase activity is
increased in:
a)
Heart attack
b)
Obstructive jaundice
c)
Pre-heapatc jaundice
d)
Prostate cancer
Which of the following is not a cause of
respiratory acidosis:
a)
Severe pneumonia
b)
Pulmonary oedema
c)
Hypoventilation
d)
Hyperventilation
Q.8
Which of the following is not a cause of
hypocalcemia:
a)
Hyperthyroidism
b)
Hypoparathyroidism
c)
Pseudohypoparathyroidism
d)
Vitamin D deficiency
Q.9
Which one of the following tests is
performed to determine the renal blood
flow:
a)
Renal clearance test
b)
Phenol sulphthalein (PSP) excretion
test
c)
Bromsulphthalein (BSP) test
d)
Para-amino hippurate (PAH) test.
P.T.O.
Q.10
Ricin is an inhibitor of:
a)
DNA synthesis
b)
RNA synthesis
c)
Protein synthesis
d)
Folic acid synthesis
Q.11
Which of the following is not a tumor
marker:
a)
Prostate specific antigen (PAS)
b)
Calbindin
c)
Alpha-foetoprotein
d)
CA-125
Q.12
Which of the following is not an anticancer drug:
a)
Methotrexate
b)
Actinomycin D
c)
L-asparaginase
d)
Benzpyrene
Q.13
Hippuric acid is derived from detoxication
of:
a)
Benzoic acid
b)
Nicotinic acid
c)
Citric acid
d)
Carbonic acid
Q.14
Acetazolamide, used as a diuretic, is an
inhibitor of:
a)
Enolase
b)
Succinate dehydrogenase
c)
Carbonic anhydrase
d)
Alcohol dehydrogenase
Q.15
Rifampicin inhibits:
a)
Transcription in prokaryotes
b)
Transcription in eukaryotes
c)
Transcription in both prokaryotes
and eukaryotes
d)
None of above
Q.16
Essential amino acid tryptophan is found
absent in:
a)
Gelatin
b)
Zein
c)
Both gelatin and zein
d)
None of the above
Q.17
Which of the followings is not a cause of
anaemia:
a)
Deficiency of copper
b)
Deficiency of L-ascorbic acid
c)
Deficiency of folic acid
d)
Deficiency of lipoic acid
Q.18
Bantus siderosis is associated with:
a)
Iron toxicity
b)
Copper toxicity
c)
Fluoride toxicity
d)
Lead toxicity
Q.19
Which of the following are not the cells of
immune system:
a)
Lymphocytes
b)
Dendritic cells
c)
Macrophages
d)
Oxyntic cells
Q.20
Severe
combined
immunodeficiency
disease (SCID) reults from:
a)
Inherited deficiency of enzyme
adenosine deaminase
b)
Inherited deficiency of enzyme
xanthine oxidase
c)
Inherited deficiency of enzyme
hypoxanthine
guanine
phosphoribosyl transferase
d)
Inherited deficiency of enzyme
glucose-6-phosphate dehydrogenase