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Giorgio Prantera Position: since 1992, Professor of Genetics at the Faculty of Sciences of the University of Tuscia. Scientific interest: eukaryotic chromosome biology, and, in particular, the relationships between structural and functional genome organizations. Research topics and publications: Mechanisms of chromosome banding and their implications for chromosome structure. The results have been published on: Science, Chromosoma, Cytogenetic and Cell Genetics, Experimental Cell Research, Heredity. Correlation between chromatin conformation, DNA methylation and gene expression in human cells. The results have been published on: Chromosoma, Cytogenetic and Cell Genetics. Genomic organization of CpG islands in human genome. The results have been published on: Chromosoma. Genomic imprinting in mammals. The results have been published on: Chromosome Research. Mealybug chromosome system as a model system to study genomic imprinting and facultative heterochromatin formation. The results have been published on: Caryologia, Genetics, Development, Genetica, Chromosoma. List of selected publications G. Prantera, S. Bonaccorsi & S. Pimpinelli (1979): Simultaneous production of Q and R bands after staining with Chromomycin A3 or Olivomycin. Science 204: 79-80 A. Rocchi, G. Prantera, V. Lanza & M. Di Castro (1984): Incipient sex chromosome differentiation in an isopod crustacean species, Asellus aquaticus. Chromosoma 89: 193-196 M. Ferraro & G. Prantera (1988): Human NORs show correlation between transcriptional activity, DNase I sensitivity and hypomethylation. Cytogenetics and Cell Genetics 47: 58-61. G. Prantera & M. Ferraro (1990): Analysis of methylation and distribution of CpG sequences on human active and inactive X chromosomes by in situ nick-translation. Chromosoma 99: 18-23. J. Del Mazo, G. Prantera, M. Torres, M. Ferraro (1994): DNA methylation changes during mouse spermatogenesis. Chromosome Research 2: 147-152. S. Bongiorni, O. Cintio and G. Prantera (1999): The relationship between DNA methylation and chromosome imprinting in the Coccid Planococcus citri. Genetics 151:1471-1478. S. Bongiorni, M. Mazzuoli, S. Masci and G. Prantera (2001): Facultative heterochromatization in parahaploid male mealybugs: involvement of a heterochromatin-associated protein. Development 128: 3809-3817. I.G. Cowell, R. Aucott, S. K. Mahadevaiah, P. S. Burgoyne, N. Huskisson, S. Bongiorni, G. Prantera, L. Fanti, S. Pimpinelli, R. Wu, D. M. Gilbert, W. Shi, R. Fundele, H. Morrison, P. Jeppesen and P. B. Singh (2002): Heterochromatin, HP1 and methylation at lysine 9 of histone H3 in animals. Chromosoma 111: 22-36. Bongiorni, S. and G. Prantera (2002): Imprinted facultative heterochromatization in mealybugs. Genetica, in press.