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Acute Otitis Media in Children Summary statement: How does the document support patient care? The purpose of this policy is to provide evidence based guidance for staff on Acute Otitis Media in Children Staff/stakeholders involved in development: Job titles only ST1 Division: Women & Child Health Department: Paediatrics Responsible Person: Chief of Service Author: Laura Whitmarsh, Dr M.Linney For use by: All clinical staff involved in prescribing and administering intravenous (IV) fluids to paediatric patients under the age of 16 years. Purpose: This guideline is to aid staff in the diagnosis and management of children with acute otitis media in the hospital This document supports: Standards and legislation NICE clinical guidance Key related documents: Tonsillitis in children 2009 Paediatric Consultant Feverish illness in children: assessment and initial management in children younger than 5 years. NICE clinical guideline 47 (2007) WSHT Paediatric antimicrobial policy accessed 2012 Approved by: Joint Paediatric Guidelines Group Divisional Governance/Management Group Approval date: October 2012 Ratified by Board of Directors/ Committee of the Board of Directors No Applicable – Divisional ratification only required Ratification Date: No Applicable – Divisional ratification only required. Expiry Date: November 2015 Review date: August 2015 If you require this document in another format such as Braille, large print, audio or another language please contact the Trusts Communications Team Reference Number: To be added by the Library Acute Otitis Media in Children Guideline Version 2 Page 1 of 8 Oct 2012 Version date Author Status 1.0 Oct 2012 Dr M Linney Live Comment 2.0 3.0 4.0 Acute Otitis Media in Children Guideline Version 2 Page 2 of 8 Oct 2012 INDEX 1.0 2.0 3.0 4.0 5.0 6.0 7.0 Aims and Scope of Policy Key points Assessment Differential Diagnosis Complications Management Auditable Standards References Acute Otitis Media in Children Guideline Version 2 Page 3 of 8 Page No. 4 4 4 5 5 5 8 8 Oct 2012 1.0 Aims and scope of this policy This guideline is based on the NICE clinical guidance “respiratory tract infections and antibiotic prescribing and recent reviews/meta analysis of acute otitis media. It aims to aid diagnosis and management of children with acute otitis media on Howard Ward, CAU and children’s A&E 2.0 Key points Acute Otitis media (AOM) is a common infection in childhood with up to 20% of under 4 year olds have one episode a year. It usually presents with otalgia, fever and hearing impairment or irritability. It is normally a self limiting illness with 80% of affected individuals having an improvement after 3 days. Bacteria cause the majority of cases, the most common ones are Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, Group A streptococcus, Staphylococcus aureus. Inappropriate antibiotic prescribing is likely to lead to drug related adverse incidents, increased prevalence of drug resistance and lead to an increase in presentations to primary care for minor illnesses. Main policy 3.0 Assessment Take a full history and perform examination to: 1. To identify relevant co-morbidities. 2. Gain an understanding of parents concerns and expectations to establish best policy for prescribing. 3. Examine to confirm diagnosis and identify any signs of complications (i.e. mastoiditis) Clinical features consistent with AOM are: Sudden onset of symptoms (usually preceded by URTI): Earache is the most common symptom. Fever, hearing loss/difficulty, tugging on ears or rubbing ears, irritability, restlessness at night are also sometimes associated with AOM Signs of AOM or middle ear effusion: Examination with an otoscope will reveal, bulging tympanic membrane, change in colour of tympanic membrane to yellow or red, there may be a rupture of the membrane with pus seen in the ear canal (symptoms are often relieved at this time). It is important to fully examine the child to help differentiate with other diagnosis as detailed below and look for complications. It should be noted that children especially those under 2 years of age may present with systemic features rather than localising features. Acute Otitis Media in Children Guideline Version 2 Page 4 of 8 Oct 2012 4.0 Differential diagnosis: 1. Mastoiditis-examine for erythema swelling and tenderness in the peri auricular area. Classically have protruding ear on affected side. A potentially serious complication of AOM 2. Impacted ear wax 3. Otitis media with effusion(part of the same spectrum of disease) 4. Otitis externa – more common in adults and often bilateral 5. Otitic barotrauma (history very important for this) 6. Referred pain-more common in older patients check for jaw dental spine symptoms or signs. Less likely if otalgia is bilateral. 5.0 Complications Common complications 1. Hearing loss-most common, conductive hearing defect, usually transient-whilst middle ear effusion persists may be up to 60db loss. 2. Perforated tympanic eardrum 3. Otitis media with effusion-common, 10% of children will have at 3 months, the younger the child the more likely that it will be persistent. 4. Otitis externa 5. Vestibular disturbance and imbalance Rare but serious complications 1. Mastoiditis-less than 1 in 1000 untreated children. May lead to cerebral complications such as abscess or sinus thrombus. 2. Cholesteatoma – cystic like structure of stratified squamous epithelium. Grows by eroding into bone. May lead to invasion of temporal bone leading to meningitis and cerebral abscess 3. Facial paralysis-may be due to presence of effusion or may represent associated mastoiditis 4. Labyrinthitis due to spread of the infection to the labyrinth may be acute or chronic 5. Sensorineural hearing loss-due to spread through the round window usually permanent. 6. Intracranial sepsis – these patient will require urgent ENT referral and full assessment including bloods If you are a suspicious of a serious complication then involve senior medical staff. (registrar or consultant of the week) at an early stage. 6.0 Management 1. Reassurance. Give advice about; Diagnosis, Natural history (4 days otitis media) 2. Analgesia & Antipyretics 3. Antibiotics. i. No antibiotics in acute otitis media this is appropriate for the majority of cases. ii. Delayed prescriptions maybe required when there are parental concerns which you are unable to alleviate. Give reassurance that antibiotics are not required Acute Otitis Media in Children Guideline Version 2 Page 5 of 8 Oct 2012 immediately as are unlikely to shorten course of illness and have side effects such as diarrhoea, vomiting, rashes. If giving a delayed prescription then give advice when they should get it i.e. significant worsening or no improvement inline with the natural history iii. iv. Consider Immediate Antibiotics in : Bilateral AOM <2 years old AOM with otorrhoea Features of systemic illness Symptoms or signs of complications (as detailed above) o If serious complication suspected-: Involve senior paediatrician, resuscitate as necessary, perform blood tests for CRP, FBC and film, U&Es LFTs blood cultures PCR for pneumococcal and meningococcal. Start IV Cefotaxime Co-morbidity – lung (including CF) heart, renal or liver disease, immunosuppression, ex-premature young children. Which antibiotics and length of treatment A five day course should be prescribed. Amoxicillin is first line, response is expected within three days-improvement in pain, resolution of pyrexia and irritability. If there is no response then they should be evaluated for occurrence of the supportive complications and an alternative antibiotic should be prescribed. Persistence of middle ear effusion doesn’t suggest treatment failure. In treatment failure augmentin may be used. clarithromycin should be used for penicillin allergic patients. 4. Decongestants and Anti histamines are not recommended, as the significant side effects outweigh the limited benefits 5. Urgent ENT referral for: Sudden onset of severe hearing loss (not associated with perforation) Sudden dizziness and nystagmus Progression to mastoiditis/ serious complications 6. Elective referrals to ENT for: Persistent effusion discharge or perforation-for more than 6 weeks More than 3 episodes in 6 months or 4 in 12 months of AOM and proven hearing loss Persistent effusion and impaired hearing for 3-6 months. Acute Otitis Media in Children Guideline Version 2 Page 6 of 8 Oct 2012 Flow Diagram For Management Of AOM No Clinical features of AOM? Yes Identify alternative diagnosis and treat appropriately Yes Signs of serious complications? Involve senior paediatrician Resuscitate if necessary Blood U&Es, co-ag, FBC, LFTs, CRP Cultures IV antibiotics-Cefotaxime NO Give advice on natural course and management of symptoms. Any of the following present? Bilateral AOM <2 years old AOM with otorrhoea Co- existing tonsillitis with 3 or more Centor criteria (tonsilar exudates, tender anterior lymphadenopathy, history of fever and absence of cough – see tonsillitis policy.) Features of systemic illness Symptoms or signs of complications (as detailed above) o If serious complication suspected-: resuscitate as necessary, perform blood tests for CRP, FBC and film, U&Es LFTs blood cultures PCR for pneumococcal and meningococcal. Start IV Cefotaxime Co-morbidity – lung (including CF) heart, renal or liver disease, immunosuppression, exYes premature young children. Urgent referral to ENT specialists. No Parental expectation or concern despite reassurance. yes Consider delayed antibiotic prescription and advice. No Reassurance and advice, no antibiotics prescribed. Consider Immediate AntibioticsAmoxicillin for 5 days or clarithromycin if penicillin allergic Acute Otitis Media in Children Guideline Version 2 Page 7 of 8 Oct 2012 7.0 Auditable Standards http://www.nice.org.uk/nicemedia/pdf/RespiratoryTractInfectionsAuditSupport.doc References: NICE clinical guideline 69: Respiratory Tract infections-antibiotic prescribing. Issue date July 2008 Infectious Diseases and Immunization Committee, Canadian Paediatric Society (CPS) Paediatrics & Child Health 1998; 3(4): 265-267. Reference No. ID 97-03 Illustrated textbook of paediatrics, 2nd edition. Tom Lissauer, Graham Clayden Mosby 2001 Institute for clinical systems improvement, Diagnosis and Treatment of Otitis Media in Children Ninth Edition/January 2008 Coleman C, Moore M. Decongestants and antihistamines for acute otitis media in children. Cochrane Database of Systematic Reviews 2008, Issue 3. Art. No.: CD001727. DOI: 10.1002/14651858.CD001727.pub4. BNF for children. 2008 edition. BMJ Group London. 2008 Feverish illness in children: assessment and initial management in children younger than 5 years. NICE clinical guideline 47 (2007). Available from: www.nice.org.uk/CG047 Acute Otitis Media in Children Guideline Version 2 Page 8 of 8 Oct 2012