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RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES KARNATAKA BANGALORE ANNEXURE- II APPLICATION FOR REGISTRATION OF SUBJECT FOR DISSERTATION 1 Name of the candidate and address Dr. PALLAVI UPPIN P.G. STUDENT, DEPARTMENT OF MATERIA MEDICA, H.K.E’S HOMOEOPATHIC MEDICAL COLLEGE & HOSPITAL, SEDAM ROAD, GULBARGA – 585105. HKE’S HOMEOPATHIC MEDICAL COLLEGE & HOSPITAL SEDAM ROAD GULBARGA- 585105 M.D(HOMOEO) MATERIA MEDICA 2 Name of the institution 3 Course of the study and subject 10-10-2012 Date of admission to the course Title of the topic “A CLINICAL STUDY ON EFFICACY OF HOMOEOPATHIC REMEDIES IN THE MANAGEMENT AND TREATMENT OF PHARYNGITIS.” Brief resume of the intended work PHARYNGITIS comes from the Need for the study greek word Pharynx Pharanx meaning Throat and the suffix –Itis means Inflammation. Therefore, it is an inflammatory condition of throat especially back of the throat( Pharynx). It is most common cause for sore throat. 4 5 6 6.1 Regardless of age, gender, among all others, the affections of pharyngitis constitute one of the most frequent reason for visiting the doctor. Around 30 million people are affected by Pharyngitis annually. Pharyngitis is classified into Acute pharyngitis is characterized by sudden onset and typically a relatively short course. Again acute is of catarrhal and purulent or ulcerative depending of the virulence of causative agent and immune capacity of the affected individual. Chronic pharyngitis is characterized by gradual onset and typically a relatively long duration. It is of catarrhal and hypertrophic or atrophic type. Cause: Direct contact with the infected person. Infectious cause: Virus are the most common causes 90% in adults, 60%-75% in children and include rhinovirus, adenovirus, para-influenza virus, herpes simplex virus, Epstein-Barr virus, cytomegalovirus. Bacteria: Group A β-hemolytic streptococci, Group C streptococci, Group G streptococci, Corynebacterium diphtheria, Aranobacterinum haemolytium, Neisseria gonorrhea,Yernisia enterocolitica. Fungi: candida may be found in immunecompromised individuals. Non-infection cause: Irritants, pollutants, chemical substances, smoking(both active and passive. Allergies: dust, certain food and drinks, pollen grains, etc. According to Allopathic school of medicine: they manage by advising bed rest, give symptomatic treatment mainly in viral infections, give analgesics, antibiotics preferably pencillin or erythromycin. Mouth washes, cough suppressants like codeine phosphate linctus. It is rather difficult to reverse the chronic changes once they have set in However, the symptoms can be elevated to a greater extent, primary etiological factors should receive proper treatment. Advices given: to avoid alcohol, smoking, exposure to irritants, spicy food, direct contact with infected person. Most of the Allopathic drugs have side effects and there is a chance of recurrence after end of the treatment, but in Homoeopathy complete system of medicine aims is to promote general health, by reinforcing the body’s own natural healing capacity. Homoeopathy means similar to the suffering the remedies used to treat sick people are actually capable of producing similar set of symptoms in a healthy person, homoeopathic remedies act at a level of energy, so we don’t treat for pharyngitis but, the person as a whole. Homoeopathy has much to offer in this condition, not only in the active phase of illness where it acts by providing prompt relief of the symptoms but is also capable of checking the further predisposition to these conditions in sensitive individuals Homoeopathy can boost the immune system to fight out the disease and to prevent sickness in the future, so number of people’s are diverting towards homoeopathy to boost up their immune system in order to fight the disease naturally. So, Homeopathic system is a safe, rapid, gentle and permanent cure for pharyngitis. It’s an effort, to see the utility of homoeopathic medicine in pharyngitis Hence I want to make an effort in dissertation on this topic. 6.2 Review of literature 1. Acute pharyngitis: Acute inflammation of the pharyngeal mucosa is an accompanying feature of many local and systemic diseases. Membranous pharyngitis Various diseases local or systemic are associated with membrane formation in the pharynx. Chronic pharyngitis: Chronic inflammation of the pharynx may be due to non-specific or specific lesions. Chronic non-specific pharyngitis. Chronic specific pharyngitis. REF NO. 1 2. Acute pharyngitis Etiology: it is very common and occurs due to varied etiological factors like viral, bacterial, fungal or others, viral causes are more common for acute pharyngitis. Acute streptococcal pharyngitis had received more importance because of It’s etiology in rheumatic fever and post-streptococcal glomerulonephritis. Chronic pharyngitis It is a chronic inflammatory condition of the pharynx. Chronic pharyngitis is of 2 types Chronic catarrhal pharyngitis Chronic hypertrophic pharyngitis Atrophic pharyngitis It is a form of chronic pharyngitis often seen in patients of atrophic rhinitis. Pharyngeal mucosa along with its mucous glands shows atrophy. REF NO. 2 3. The pharynx Acute catarrhal pharyngitis This is not well defined affection it is usually accompanied by acute rhinitis on one hand and laryngitis on the other hand. The tonsils often participate in the inflammation Acute septic pharyngitis This term includes a series of severe infective inflammation oedematous, phlegmonous and gangrenous. Pharyngitis, laryngitis, and Ludwig’s Angina. Chronic Pharyngitis Etiology: Chronic Pharyngitis is usually secondary to chronic infections in the nasal sinuses, tonsils, or teeth. REF NO. 3 4. Acute Pharyngitis Acute sore throat is the term employed. It is an acute inflammation of the mucous membrane lining the pharynx and frequently a part of a general inflammation affecting the nose and larynx Homoeopathic remedies for management of pharyngitis Aconite 3x : the invasion is sharp, with active systemic reaction indicated by fever or repeated attacks of chills. Apprehensiveness and sense of impending severe illness. Apis 3x: constricting, burning, and stitching pains. The local condition presents marked oedema. The mucous membranes are shiny and puffed. Chronic Pharyngitis This is simple catarrhal, granular or lateral hypertrophy of the pharyngeal mucous membrane. Ars.iod 2x: follicular and glandular enlargement, the mucous membrane between the area of hypertrophy in anaemic. Atrophic Pharyngitis: This condition is characterized by abnormal dryness of pharynx and is observed particularly in individual who are anaemic or debilitated, in diabetics and those afflicted with tuberculosis and contracted kidneys. Homoeopathic, china tincture and the iodide of arsenic 2x are frequently indicated because of the type of patient condition with which atrophic pharyngitis is frequently associated. REF NO. 4 5. Acute Pharyngitis The character and severity of the symptoms depends on the cause and nature of the attack`. Amm – Carb : when swallowing there is sensation of foreign body in the throat. Sore throat as if something is stitching in it, especially in the morning and in the evening. putrid sore throat. Chronic follicular pharyngitis Calc-Carb : sore throat as if from a plug or a swelling in the gullet. Constriction in the throat and cramp like contraction of the gullet. Affection in the throat after straining the back, hawking up of mucus. Atrophic pharyngitis Sabadilla : Pain in the throat as if caused by a plug or an internal swelling during deglutition. Dryness in the throat. REF NO. 5 6. Aesculus Hippocastanum I have used with very good results in coryza and sore throat. Sensation of rawness, sensitive to inhaled cold air, in the throat it has the same sensation of a rawness, both in acute and in chronic follicular pharyngitis to which it is often a good remedy. Phytolococca Decandra I have done some good work with this remedy in follicular pharyngitis, especially when in public speakers the voice gave out from over work and there was much burning in the throat as of a hot substance there in this kind of sore throat I have the best success with the remedy very high. REF NO. 6 7. Kali- Bichromium We find kali- bichromium indicated in the forms of inflammation of the throat other then diphtheritic, thus it is called for in follicular pharyngitis, the follicles of the throat becomes hypertrophied and looks like little tubercles on the pharyngeal walls. Kali-carbonicum : It acts causing a quite a series of catarrhal symptoms. There is a sticking sensation in the pharynx, as from a fish bone lodged there, whenever the patient becomes cold. REF NO. 7 8. Laryngitis and pharyngitis Wyethia Helenoides Excellent remedy for pharyngitis characterized by constant irritation in the pharynx that makes the person clear the throat like crazy, this does not bring any relief of the patient. The pharynx feels dry and swollen constant tickling in the epiglottis, this leads to coughing. It is useful for Pharyngitis in school teachers, singers and other professional who use to do lots of public speaking. REF NO. 8 9. Pharyngitis Acute sore throat is the form given to pharyngitis. It is inflammation of the mucous membrane lining the pharynx and is frequently a part of general inflammation affecting the nose and larynx. It is seen as a part of general acute upper respiratory tract infection so called general cold. REF NO. 9 10. Complete and permanent cure of Pharyngitis. Treatment: Most sore throat are caused by viruses. Antibiotics do not help. The best treatment is any condition is to build your immune system up. This in far superior to looking to kill off bacteria. The bacteria aren’t the course of the malady, your immune system is compromised. There are many homoeopathic medicine which treat a throat. REF NO. 10 6.3 Objective of the study 1. To study and assess the efficacy of homeopathic medicines in treating PHARYNGITIS. 2. To evolve the group of remedies commonly indicated in the management of PHARYNGITIS. 7 7.1 7.2 7.3 7.4 Material and methods Source of data HKE’S HOMEOPATHIC MEDICAL COLLEGE AND HOSPITAL, IPD AND OPDs. 1. By interrogations of the individual Method of collection of cases data including sampling 2. By physical examination of the patient procedure if any and routine lab investigation. 3. Sample size- 30 cases are to be studied. 4. Sampling procedure- samples collected using the simple random sampling technique. 5. Data analysis by chi squire test. 6. Inclusive criteriaPatients of all age group Both Sexes From all socio-economic status 7. Exclusive criteriaRheumatic fever Glomerulonephritis Tonsillitis Sinusitis Specific infection of pharynx like Tuberculous, syphilis, lupus vulgaris. Peritonsillar abscess Does this study requires any investigations or interventions to be conducted on patients or other humans or animals? If so please describe briefly Whether ethical clearance has been obtained from your institution in case of 7.3 8. Duration of study 1-05-2013 to 30-04-2015 The study requires the following investigations to be conducted on patients. Complete blood count. Throat swab for smear culture X-rays ( if required) Yes, the ethical clearance has been obtained from institution. 8 List of references Ref No.1 Dr.Mohammad Maqbool Suhail Maqbool Text Book Of Ear, Nose And Throat Diseases. Chapter 46 11th Edition Jaypee Brothers Page No. 279-281 Ref No.2 Dr. P.L. Dhingra Diseases Of Ear, Nose And Throat 4th Edition Elsevier Indian Pvt Ltd Chapter No. 49 Acute And Chronic Pharyngitis Page No. 236-238 Ref No.3 Dr.Price’s Textbook Of The Practice Of Medicine 12th Edition The English Language Book Society And Oxford University Page No. 613, 614 And 848, 849 Ref No.4 Dr.Joseph V.F. Clay Homoeopathic Treatment Of Diseases Of The Nose And Throat B.Jain Publisher’s Reprint Edition 1998 Page No. 113 – 120 Ref No.5 Dr.P. Sivaraman Ear, Nose And Throat Troubles Cured With Homoeopathy B.Jain Publisher’s Pvt Ltd Reprint Edition 1997 Page No.270-273,14,43,205 Ref No. 6 Dr E.B. Nash. MD Leaders In Homeopathic Therapeutics. B. Jain Publications Reprint Edition - 2000 – 01 Page No. 181 , 447 Ref No. 7 Dr. E.A. Farrington MD Clinical Materia Medica B. Jain Publications 4th Edition Reprint Edition- 1994 Page No. 722, 730, 740 Ref No.8 Dr. Farokh J.M. The Homoeopathic Heritage Bringing Classical And Contemporary Homoeopathy Together Vol No. 35 Common Ent Problems In My Practice Page No. 10 Ref No. 9 Homoeopathy For All Vol. 4 No.45 Sep 15 2003 Diseases Of Nose And Throat In Children’s Page No. 41 Ref No. 10 www.sheryna.in/Complete-AndPermanent-Cure-Of-PharyngitisWit... 9 Signature of candidate 10 Remarks of guide 11 Name and designation of (in block letters) 11.1 Signature 11.2 Co-guide (if any) 11.3 Signature 11.4 Head of the department 11.5 Signature 12 Remarks of the chairman and principal 12.1 Signature Dr. MAHADEV PASAR M.D. (Homoeo) Prof. Of Materia Medica Dept Hke’s Homeopathic Medical College & Hospital Gulbarga. Dr. RAJESHWARI. K M.D. (Homoeo) Prof. & H.O.D Department Of Materia Medica, H.K.E’S Homoeopathic Medical College & Hospital Gulbarga