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Transcript
Hepatitis Terminology
ABBREVIATION
TERM
COMMENTS
HAV
Hepatitis A virus
Anti-HAV
Antibody to HAV virus
IgM anti-HAV
IgM class antibody to HAV virus
HBV
Hepatitis B surface antigen
HBsAg
Hepatitis Be surface antigen
HBeAg
Hepatitis Be antigen
Etiologic agent of “infectious”
hepatitis; Not bloodborne; Fecal/Oral
Detectable at onset of symptoms;
lifelong persistence
Indicates recent infection with
hepatitis A; tests positive up to 4-6
months after infection
Etiologic agent of “serum” or “long
incubation” hepatitis; also known as
Dane particle
Surface antigen(s) of HBV detectable
in large quantity in serum; several
subtypes
Soluble antigen; antigen correlates
with HBV replication, higher titer HBV
in serum, and infectivity of serum
HBcAg
Hepatitis B core antigen
No commercial test available
Anti-HBs
Antibody to HBsAg
Anti-HBe
Antibody to HBeAg
Indicates past infection with, and
immunity to; HBV; passive antibody
from HBIG, or immune response
from hepatitis B vaccine
Presence in serum of HBsAg carrier
suggests lower titer of HBV
Anti-HBc
Antibody to HBcAg
Indicates past infection with HBV at
some undefined time
IgM Anti-HBc
IgM class antibody to HBcAg
HCV
Hepatitis C virus
Anti-HCV
Antibody to Hepatitis C virus
HEV
Hepatitis E virus
HDV
Delta virus
Indicates recent infection with HBV;
tests positive for 4-6 months after
infection
Name for one virus associated with
PT-NANB; similar to HBV; contracted
through blood transfusions
Marker of previous HCV infection;
does not specifically indicate
immunity or viral carrier state
Proposed name for ET-NANB; not
bloodborne
Etiologic agent of delta hepatitis, only
causes infection in presence of HBV
HDAg
Delta antigen
Detectable in early acute infection
Anti-HDV
Antibody to delta antigen
Ig
Immune globulin
HBIG
Hepatitis B immune globulin
Indicates past/present infection with
delta virus
Contains antibodies to HAV; lower
titer antibodies to HBV
Contains high-titer antibodies to HBV