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Hepatitis Terminology ABBREVIATION TERM COMMENTS HAV Hepatitis A virus Anti-HAV Antibody to HAV virus IgM anti-HAV IgM class antibody to HAV virus HBV Hepatitis B surface antigen HBsAg Hepatitis Be surface antigen HBeAg Hepatitis Be antigen Etiologic agent of “infectious” hepatitis; Not bloodborne; Fecal/Oral Detectable at onset of symptoms; lifelong persistence Indicates recent infection with hepatitis A; tests positive up to 4-6 months after infection Etiologic agent of “serum” or “long incubation” hepatitis; also known as Dane particle Surface antigen(s) of HBV detectable in large quantity in serum; several subtypes Soluble antigen; antigen correlates with HBV replication, higher titer HBV in serum, and infectivity of serum HBcAg Hepatitis B core antigen No commercial test available Anti-HBs Antibody to HBsAg Anti-HBe Antibody to HBeAg Indicates past infection with, and immunity to; HBV; passive antibody from HBIG, or immune response from hepatitis B vaccine Presence in serum of HBsAg carrier suggests lower titer of HBV Anti-HBc Antibody to HBcAg Indicates past infection with HBV at some undefined time IgM Anti-HBc IgM class antibody to HBcAg HCV Hepatitis C virus Anti-HCV Antibody to Hepatitis C virus HEV Hepatitis E virus HDV Delta virus Indicates recent infection with HBV; tests positive for 4-6 months after infection Name for one virus associated with PT-NANB; similar to HBV; contracted through blood transfusions Marker of previous HCV infection; does not specifically indicate immunity or viral carrier state Proposed name for ET-NANB; not bloodborne Etiologic agent of delta hepatitis, only causes infection in presence of HBV HDAg Delta antigen Detectable in early acute infection Anti-HDV Antibody to delta antigen Ig Immune globulin HBIG Hepatitis B immune globulin Indicates past/present infection with delta virus Contains antibodies to HAV; lower titer antibodies to HBV Contains high-titer antibodies to HBV