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COLPOSCOPY Women's questions answered Do smears work? The numbers of cases of cervical cancer has been falling dramatically since the introduction of computerised call and recall for women to regularly have their cervical smears. Since 1988 there has been a reduction of more than 40% in the registration of new cases and the rate has continued to fall by about 7% per year. This however depends upon all eligible women attending for their smears when invited and in England means that all women aged 25-65 years should have a smear every 3 years until they are 50 then every 5 years thereafter. The frequency of smear taking is slightly different in Northern Ireland, Wales and Scotland. More cervical cancers are detected at a microscopic stage and can be treated in some cases without major surgery. Surgeons have also improved surgical techniques involving vaginal and laparoscopic (keyhole) procedures. Radiotherapy techniques have also improved. The cervical screening story in the UK is a success story but there is no room for complacency and the most important message, is to ensure that you attend for your smear is taken when it is due. I have an abnormal smear. What is the chance that I have cancer? Whilst about 1 in 20 women will have an abnormal smear after a given test only about 1 in 2000 will have cervical cancer. That means approximately 1% of women with any grade of abnormal smear will have a cancer. So statistically speaking the risk that you have already developed cervical cancer is very small even if your smear is abnormal. We realise though that women worry about this possibility and this is where colposcopy is really helpful. In the majority of women the colposcopy is really reassuring as it documents more clearly what the situation is. So the advice is if you have been referred to colposcopy it is important that you keep your appointment. Hiding from clinic will not make the abnormal cells get better! I have had an abnormal smear test result and I am pregnant. What should I do? This will depend on the smear test result. If you have had just one abnormal smear with a low grade abnormality it might get better by itself and colposcopy may not be necessary - you will simply need to have the smear test repeated three months following the pregnancy. It is important to remember that pregnancy has no adverse effect in the progression of abnormal cells (CIN) or the development of cervical cancer. If a colposcopy has been recommended and an appointment has been made with a colposcopy clinic then you should attend. Colposcopy will not in any way harm the pregnancy and can provide valuable and reassuring information. In many cases treatment and even biopsy s deferred until after the pregnancy. It is very important though, to follow through with the suggested plan, to make sure you return to having normal smear tests. Can treatment for abnormal cells cause me problems in future pregnancy? Any treatment involves a balance between removing abnormal cells on the one hand and minimising any possible harm on the other hand. Clearly the more of your cervix which has been removed then the less supporting tissue for future pregnancies. Your colposcopist will recognise the importance of the cervix to support future pregnancies and will tend to remove as little tissue as possible while making sure the treatment is successful. Women who have had treatment for abnormal cells by loop excision may be at minor increased risk to deliver prematurely or preterm in later pregnancies. Or those who have had repeated treatments may also result in early delivery. If you have had multiple treatments and are pregnant or considering a pregnancy then you should speak to your GP or obstetrician. While there currently appears to be no ideal way to judge this risk, your obstetrician or gynaecologist may advise a special scan early in pregnancy to measure the length of your cervix. In most cases this is normal but if not your doctor may recommend a cervical stitch (or cerclage) to provide additional support. This is generally fitted when you are pregnant with a short general anaesthetic and removed whilst you are awake shortly before your baby is due. Will treatment to my cervix alter my periods? There is no evidence that the flow at menstruation is increased or that cycle regularity is altered by treatment. Rarely periods may disappear particularly after a cone biopsy (this is the treatment that is usually performed with a general anaesthetic) but this is due to a rare complication called cervical stenosis, where the cervix becomes blocked and cramp like period pains, continue because of blood becoming trapped in the uterus (or womb). This can usually be dealt with by a procedure to open the cervix and release the trapped blood. What is HPV and is my abnormal smear due to sex? There are 2 questions here. HPV or human papilloma virus is an extremely common virus that is almost always caught by sexual intercourse. Approximately 8 out of 10 adults have had the infection at some time and rarely produce any effects but about 5% of women have abnormal smears. 1-2% will develop pre-cancerous cells (CIN) and a tiny minority of these progress to get cervical cancer despite the efforts of the screening programme. So although HPV is sexually transmitted it is not a sexually transmitted disease that requires a visit to a Sexual Health Clinic. Some abnormal smears with mild changes may not be due to HPV but most abnormal smears are due to the effects of HPV on the cervix. There is no blame to attach to your current or any other partner or to yourself. The one visible abnormality some types of HPV can produce is warts on the vulva or the anus. This is a slightly different situation. These can be treated by the local Sexual Health Clinic. If you have these then your partner would also need examination and possible treatment. Usually a topical cream or freezing of warts is all that is required. What about my coil? If you have a coil (or IUCD/ Mirena IUS) then this need not be removed, if you are expecting treatment in colposcopy clinic. Practice amongst colposcopists is divided. Some colposcopists will consider removing it if you not had sexual intercourse for the preceding 5 days, but some colposcopists will perform a colposcopy and if a loop excision form of treatment is needed, then consider performing the loop ‘around’ the coil and coil threads. Sometimes the threads are inadvertently cut but this is not a problem as a coil can be removed (when you no longer wish to use it) without the threads. My pill and cervical cancer The combined oral contraceptive pill is associated with a very slightly increased risk of cervical cancer. A recent series of publications found this to be in women that have HPV. This is not very helpful, as HPV almost always has no symptoms (except rarely causing genital warts due to some types of HPV) and most adults at some stage of their lives do have HPV, although in most cases the infection is short lasting (a matter of months). Family planning doctors strongly recommend that women requiring contraception should use a reliable method. The combined pill is a good method of contraception. If you have an abnormal smear and are taking the combined pill, you should continue to take the pill. It has no effect on making any changes occur any faster. Does cervical cancer run in the family? No. There is no evidence that daughters and other female relatives of women with abnormal smears, pre-cancerous cells (CIN) or cervical cancer have an increased risk of abnormal smears, pre-cancerous cells or cervical cancer. Cervical smear abnormalities are common and it is not unusual for one or more family members to have had an abnormal smear, but there is no inherited predisposition to cervical abnormalities, CIN or cervical cancer. Is a hysterectomy the answer? A hysterectomy is rarely of any help to women with abnormal smears. Studies have shown that women who have hysterectomies (having the uterus or womb and the cervix removed) for pre-cancerous cells (CIN) are less likely to have pre-cancerous cells on the vagina but are not less likely to get a cancer (as the cervix will have been removed this would then be in the vagina). Gynaecologists are therefore careful before considering a hysterectomy for women with pre-cancerous changes in the cervix. It may be recommended after 2 or 3 local treatments have failed to remove a pre-cancerous problem, or if for technical reasons further smears cannot be taken from a cervix having had multiple treatments. Other women suitable for hysterectomy may have other difficulties such as heavy periods and abnormal cells making a hysterectomy a practical common solution. A hysterectomy may be recommended for an early cervical cancer. In all cases detailed discussion with your gynaecologist is required to decide whether you can have the hysterectomy as a vaginal, abdominal or laparoscopic (or keyhole) procedure and whether you should keep your ovaries or have them removed Contacts/Further Information Snr Sr Nurse Colposcopist 01245 513090 Monday and Thursdays 730- 6 Colposcopy Secretary 01245 513090 Monday – Friday 0800-1630 Gynaecology Ward 01245 514921 24 Hours Sc/Ckp June 2011