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PINK DISEASE SUPPORT GROUP PO Box 5120, Eagleby, Qld
PINK DISEASE SUPPORT GROUP PO Box 5120, Eagleby, Qld

... wants to know about their descendants (if any). The Survey can be filled in either by the Pink Disease Survivor, or if they are unable to complete the survey, then another person can complete it on their behalf. This combined Pink Disease Survivor/Descendants survey is extremely important partly bec ...
Monoclonal Antibodies, Blood-Brain Barrier and Disability in
Monoclonal Antibodies, Blood-Brain Barrier and Disability in

... probably drive the pathology of MS and have been shown to house B cells and plasma cells,5 indicating that B cells migrate to the brain and can be sustained locally within the CNS. Plasma cells do not carry CD20 cell surface molecules and are not affected by anti-CD20 MAbs. Although apparently restr ...
Communicating Research to the General Public
Communicating Research to the General Public

... can be monitored from the outside. The advantages are that we are observing the molecules in their natural state along with their natural components, but the disadvantages are that we cannot alter the environment too much to observe its effects on the molecule in question. In vitro on the other hand ...
CNS_Carlson_11_24_03
CNS_Carlson_11_24_03

... 7-27% of persons with CD4<200 have some impairment including:  decreased attention and concentration  psychomotor slowing  personality change, loss of initiative, drive, animation  hyperreflexia, ataxia, frontal release signs ...
Iron, Aging, and Neurodegeneration
Iron, Aging, and Neurodegeneration

... reactions. The regulation of such reactions can be both positive and negative as one results in maintaining cellular activity essential for life while the opposite can result in the generation of harmful reactive chemical species of oxygen or nitrogen. The production of reactive oxygen species (ROS) ...
Meaning from sensory information
Meaning from sensory information

... Since more than half a century we are able to listen to the firing of single neurons. Neuroscientists have developed methodologies to study the involvement of neurons in different areas in a large variety of tasks. But complex brain processes are clearly related to the activity of large neural popul ...
Human Body Systems Review
Human Body Systems Review

... Same story on Fox http://video.foxnews.com/v/4697437187001/teen-girl-lifts-truck-off-of-father-saves-family-fromfire/?#sp=show-clips ...
c) people with a family history of CJD
c) people with a family history of CJD

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... Longevity: A man 90 years old will be considered young, 135 more mature and there will be a minimum of senility because the heavy cholesterol which determines the age of our arteries will be absent Nutrition: Synthetic foodstuff will bring an end forever to famine and starvation Communicable disease ...
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Materials - Web Adventures
Materials - Web Adventures

... The game begins at the headquarters for the Neuropolis Center for Disease Control (NCDC). Zack Laurer, head of the Counter Terrorism Unit (CTU) for Neuropolis, contacts the Reconstructors through the video screen. The player learns from Zack that a terrorist organization is threatening a zoonotic at ...
Transglutaminase Is Linked to Neurodegenerative Diseases
Transglutaminase Is Linked to Neurodegenerative Diseases

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Multiple Sclerosis: Current Trends in Treatment
Multiple Sclerosis: Current Trends in Treatment

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Neurotoxicity of reactive aldehydes
Neurotoxicity of reactive aldehydes

... 2002; Yan et al., 2005). In the case of aldehyde-mediated cell death, our study provides direct evidence for the ability hydroxylamines, but not anti-oxidants, to protect cells against reactive aldehydes. As a result of the diverse biochemical sources of reactive aldehydes, we hypothesized that a dr ...
Basic Organization of the Nervous system
Basic Organization of the Nervous system

... Neural tissue of the CNS and PNS contains two general categories of cells: neurons and supportive cells. The central nervous system (CNS) consists of about 10% neurons and 90% neuroglia (supportive cells). The CNS contains approximately 10 billion neurons. While the PNS contains all three morpholog ...
Acute Disseminated Encephalomyelitis (ADEM) Secondary to
Acute Disseminated Encephalomyelitis (ADEM) Secondary to

... greater number than multiple sclerosis, have poor definitions, and are more likely to involve gray matter such as the basal ganglia [3,6]. Such a pattern was evident in our patient’s neuroimaging studies. CSF studies in our patient demonstrated the presence of oligoclonal bands and an elevated IgG i ...
Acid-Base Imbalance
Acid-Base Imbalance

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• ES cells from the inner cell mass can give rise to all three germ

... motor neuron disease, a progressive and fatal neurodegenerative disorder caused by degeneration of motor neurons. There is no known cause for ALS in ~95% of cases. There is a known hereditary factor for familial ALS (FALS), a condition known to run in families that only accounts for ~5% of all cases ...
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... Conformational changes in BCL-2 family members during apoptosis. BAX undergoes extensive conformational changes during the mitochondrial translocation process. The protein changes from a soluble cytoplasmic protein in healthy cells to one that appears to have at least 3 helices inserted in the mito ...
Multiple sclerosis (MS) –
Multiple sclerosis (MS) –

... that’s why it provokes exacerbations. β - Interferonum inhibits production of γ – interferonum, increases activity of T – suppressors, has antiproliferative, antiviral and immune modulating properties. Rebif – is a modern human β – interferonum produced by “Serono” production. It is used in dose 6 – ...
Is MS an inflammatory or primary degenerative disease
Is MS an inflammatory or primary degenerative disease

... Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system, which leads to the development of focal inflammatory lesions with secondary axonal damage. This concept has recently been challenged by several observations, suggesting that in MS neurodegeneration may occur ind ...
Recombinant Human Fibroblast Growth Factor, acidic (rhFGFa
Recombinant Human Fibroblast Growth Factor, acidic (rhFGFa

... acid homology. Unlike the other members of the family, they lack signal peptides and are apparently secreted by mechanisms other than the classical protein secretion pathway. Acidic FGF has been found in brain, retina, bone ma osteosarcoma cells. FGF contains three cysteine residues, but the reduced ...
Virus & Bacteria PPt Notes
Virus & Bacteria PPt Notes

... T cells and B cells • Both are white blood cells • Regulated by helper T cells • B cell response – defense that aids the removal of extracellular pathogens – B cells • Stay in lymph nodes & organs • Mature in bone marrow • T cell response – destruction of intracellular pathogen by cytotoxic T cells ...
Unit 2: Homeostasis and Immunity
Unit 2: Homeostasis and Immunity

... research. Use the textbook and review book to define the major function(s) of the body system as well as major organs of that organ system.  We will jigsaw after small group work, so it is imperative that all group members act as recorders today!!! ...
The retina as a window to the brain—from eye research to CNS
The retina as a window to the brain—from eye research to CNS

... brain. c | Injury to the optic nerve produces, in a manner similar to other CNS neurons, an environment that is both hostile to survival of neurons that were spared in the primary insult and inhibitory to regeneration of severed axons. d,e | Similar to the CNS, the eye has a unique relationship with ...
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Neurodegeneration



Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons. Many neurodegenerative diseases including amyotrophic lateral sclerosis, Parkinson's, Alzheimer's, and Huntington's occur as a result of neurodegenerative processes. Such diseases are incurable, resulting in progressive degeneration and/or death of neuron cells. As research progresses, many similarities appear that relate these diseases to one another on a sub-cellular level. Discovering these similarities offers hope for therapeutic advances that could ameliorate many diseases simultaneously. There are many parallels between different neurodegenerative disorders including atypical protein assemblies as well as induced cell death. Neurodegeneration can be found in many different levels of neuronal circuitry ranging from molecular to systemic.
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