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Asthma Therapy for 2006
Asthma Therapy for 2006

... • Topical nasal steroids are the most potent treatment for allergic rhinitis • Anticholinergic nasal sprays may help for vasomotor rhinitis/non allergic rhinitis • Mast cell stabilizers must be used several times a day for many days before it starts working • Nasal decongestant cause a rebound effe ...
Asthma and immune dysregulation: A tale of antibodies “gone bad”
Asthma and immune dysregulation: A tale of antibodies “gone bad”

... Reactive airway disease (RAD or “asthma”) results from reversible airway obstruction, which can be triggered by a variety of mechanisms. Although bronchial constriction can be induced by exposure to cold air, by viral or Mycoplasma infections, or by local irritants such as sulfur dioxide, more than ...
INTERNATIONAL MEDICAL REVIEW ON DOWN`S SYNDROME
INTERNATIONAL MEDICAL REVIEW ON DOWN`S SYNDROME

... responsible for the production of antibodies against parasites and allergens, with other cytokines involved (IL-4, IL-13, etc.). The Th1/Th2 response is balanced, such that the production of antibodies against pathogens is guaranteed by the superior activity of Th1. The production of allergenspecifi ...
Document
Document

... MARKED THICKENING OF THE BASEMENT MEMBRANE OF BRONCHIAL MUCOSA, HYPERTROPHY OF BRONCHIAL SMOOTH MUSCLE, HYPERTROPHY OF BRONCHIAL MUCOUS GLANDS, EOSINOPHILS AND CHRONIC INFLAMMATORY CELLS IN THE BRONCHIAL WALL, INC. NUMBER OF MAST CELLS, PRESENCE OF MUCOUS IN BRONCHI CONTAINING LARGE NUMBERS OF EOSIN ...
causes
causes

... with particular sign or symptom • The techniques of examination • Be able to correlate the findings with common diseases ...
Immediate Hypersensitivity (Hypersensitivity type 1)
Immediate Hypersensitivity (Hypersensitivity type 1)

... 1 – seasonal allergic rhinitis ( SAR ) : - often related with outdoor allergens - tree pollens in early spring - grass pollens in spring & summer - weed pollens in summer & autumn ...
Allergic Rhinitis
Allergic Rhinitis

... • Most common disease • 20% adult population ...
Application of management guidelines to the assessment of new
Application of management guidelines to the assessment of new

... drive improved management of COPD. However, the guidelines have also been used increasingly by regulatory authorities to define the requirements for new agents to gain approval, a role that they were never designed to fill. The GOLD guidelines provide a working definition of COPD as a disease state ...
Generation of CNS-1 deficient mice
Generation of CNS-1 deficient mice

... Asthma reaches prevalence levels of 8%-12% in some urban Westernized populations. Allergic asthma is predominantly a disease of childhood. Consider the impact of genetics, environment and development in constructing a model to explain the immunologic underpinnings explaining the increasing prevalenc ...
PowerPoint - UCSF Immunology Program
PowerPoint - UCSF Immunology Program

... Asthma reaches prevalence levels of 8%-12% in some urban Westernized populations. Allergic asthma is predominantly a disease of childhood. Consider the impact of genetics, environment and development in constructing a model to explain the immunologic underpinnings explaining the increasing prevalenc ...
Construction of a new strain of mice that lack mast cells and set
Construction of a new strain of mice that lack mast cells and set

... Construction of a new strain of mice that lack mast cells and set-up of a mouse asthma model Behdad Zarnegar Asthma  is  a  chronic  inflammatory  disease  of  the  airways  which  causes  recurrent  episodes  of  coughing,  wheezing,   chest   tightness   and   ...
Pulmonary Oedema
Pulmonary Oedema

... associated plasma exudation, oedema, smooth muscle hypertrophy, mucous plugging and epithelial damage. The disease often ‘flares up’ with viral infections – which often cause a loud wheeze. Aetiology Intrinsic – this often starts in middle age, and is sometimes called late onset asthma. You cannot f ...
Allergic reactions
Allergic reactions

... The immune system begins making a special type of antibody to these substances, which under normal conditions would not stimulate the immune system. These antibodies cause cells in the body to release histamines, which cause many allergic symptoms, such as extra fluid in the nasal pathways, difficul ...
Smoke and your health - Tasmania Fire Service
Smoke and your health - Tasmania Fire Service

... smoke. However changes in weather conditions and other factors can affect where smoke from a planned burn may travel. If people can smell smoke, it can be a risk to their health and they need to ensure they take the necessary precautions to protect themselves against it. ...
Respiratory Disorders
Respiratory Disorders

... Symptoms usually last about 1 week Treatment: take medications to treat symptoms (analgesic, antipyretics, rest, antihistamines) ...
Mechanisms of neutrophil accumulation in obstructive airways disease
Mechanisms of neutrophil accumulation in obstructive airways disease

partner search
partner search

... Main research areas: molecular biology,genomics,identification of disease patterns Short description: In recent years, worldwide and in Kazakhstan, the number of patients with asthma and chronic obstructive pulmonary disease (COPD) progressively increases. Genetic susceptibility and environmental fa ...
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Asthma



Asthma (from the Greek ἅσθμα, ásthma, ""panting"") is a common chronic inflammatory disease of the airways characterized by variable and recurring symptoms, reversible airflow obstruction and bronchospasm. Common symptoms include wheezing, coughing, chest tightness, and shortness of breath.Asthma is thought to be caused by a combination of genetic and environmental factors. Its diagnosis is usually based on the pattern of symptoms, response to therapy over time and spirometry. It is clinically classified according to the frequency of symptoms, forced expiratory volume in one second (FEV1), and peak expiratory flow rate. Asthma may also be classified as atopic (extrinsic) or non-atopic (intrinsic) where atopy refers to a predisposition toward developing type 1 hypersensitivity reactions.Treatment of acute symptoms is usually with an inhaled short-acting beta-2 agonist (such as salbutamol) and oral corticosteroids. In very severe cases, intravenous corticosteroids, magnesium sulfate, and hospitalization may be required. Symptoms can be prevented by avoiding triggers, such as allergens and irritants, and by the use of inhaled corticosteroids. Long-acting beta agonists (LABA) or antileukotriene agents may be used in addition to inhaled corticosteroids if asthma symptoms remain uncontrolled. The occurrence of asthma has increased significantly since the 1970s. In 2011, 235–300 million people globally were diagnosed with asthma, and it caused 250,000 deaths.
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