Microbiology bio 123
... There are three clinical stages (not everyone goes through all three) Primary syphilis: 1. Development of chancre (chancre is specific to syphilis) Can be anywhere. Very contagious. 2. Hard ridge around the edge, and is painless 3. Will reside without treatment 4. Chancre is contagious and can be fo ...
... There are three clinical stages (not everyone goes through all three) Primary syphilis: 1. Development of chancre (chancre is specific to syphilis) Can be anywhere. Very contagious. 2. Hard ridge around the edge, and is painless 3. Will reside without treatment 4. Chancre is contagious and can be fo ...
Review for Final exam
... 4. Rash on palms and soles - Rocky Mountain Spotted fever, and secondary syphilis 5. Non painful chancre - Primary syphilis 6. Gummas - tertiary syphilis 7. Erythema migrans, Bull's eye rash - Lyme disease 8. buboes - plague 9. rice watery stools - Cholera 10. Flaccid paralysis - botulism 11. Grayis ...
... 4. Rash on palms and soles - Rocky Mountain Spotted fever, and secondary syphilis 5. Non painful chancre - Primary syphilis 6. Gummas - tertiary syphilis 7. Erythema migrans, Bull's eye rash - Lyme disease 8. buboes - plague 9. rice watery stools - Cholera 10. Flaccid paralysis - botulism 11. Grayis ...
Spirochetes and Rickettsiae
... a. Another way to diagnose syphilis: 1. Non-Treponemal Tests (Rapid Plasma Reagin, Venereal Disease Research Laboratory) a. Screeinng test (inexpensive, easy, and quick, but “false positive” results may occur) b. Cardiolipin (extracted from beef hearts), lecithin, cholesterol antigen c. Can be titer ...
... a. Another way to diagnose syphilis: 1. Non-Treponemal Tests (Rapid Plasma Reagin, Venereal Disease Research Laboratory) a. Screeinng test (inexpensive, easy, and quick, but “false positive” results may occur) b. Cardiolipin (extracted from beef hearts), lecithin, cholesterol antigen c. Can be titer ...
T pallidum
... - Not specific (false positive can occur with other conditions such us pregnancy , HIV, TB, and rheumatoid arthritis - Not very sensitive in early syphilis, specially in the first 2-3 weeks after the infection (false negative) ...
... - Not specific (false positive can occur with other conditions such us pregnancy , HIV, TB, and rheumatoid arthritis - Not very sensitive in early syphilis, specially in the first 2-3 weeks after the infection (false negative) ...
Infectious Diseases and Obstetrics: Then and Now
... was used for treatment and for the first time saw a decrease in prevalence • The wonder drug penicillin was discovered in the 1940s • We have intermittent increases over the last few decades associated often with drug issues but overall a significant decrease. • Prenatal screening has played a signi ...
... was used for treatment and for the first time saw a decrease in prevalence • The wonder drug penicillin was discovered in the 1940s • We have intermittent increases over the last few decades associated often with drug issues but overall a significant decrease. • Prenatal screening has played a signi ...
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... Signs and symptoms of syphilis Not all people with syphilis develop symptoms. Syphilis evolves in 3 stages: Stage 1 (or “primary” syphilis): One or more lesions (usually painless) appear at the spot where the bacteria entered the body. At first, pimples appear and evolve into ulcers (large lesions ca ...
... Signs and symptoms of syphilis Not all people with syphilis develop symptoms. Syphilis evolves in 3 stages: Stage 1 (or “primary” syphilis): One or more lesions (usually painless) appear at the spot where the bacteria entered the body. At first, pimples appear and evolve into ulcers (large lesions ca ...
Syphilis
Syphilis is a sexually transmitted infection caused by the spirochete bacterium Treponema pallidum subspecies pallidum. The primary route of transmission is through sexual contact; it may also be transmitted from mother to fetus during pregnancy or at birth, resulting in congenital syphilis. Other human diseases caused by related Treponema pallidum include yaws (subspecies pertenue), pinta (subspecies carateum), and bejel (subspecies endemicum).The signs and symptoms of syphilis vary depending in which of the four stages it presents (primary, secondary, latent, and tertiary). The primary stage classically presents with a single chancre (a firm, painless, non-itchy skin ulceration), secondary syphilis with a diffuse rash which frequently involves the palms of the hands and soles of the feet, latent syphilis with little to no symptoms, and tertiary syphilis with gummas, neurological, or cardiac symptoms. It has, however, been known as ""the great imitator"" due to its frequent atypical presentations. Diagnosis is usually made by using blood tests; however, the bacteria can also be detected using dark field microscopy. Syphilis can be effectively treated with antibiotics, specifically the preferred intramuscular benzathine penicillin G (or penicillin G potassium given intravenously for neurosyphilis), or else ceftriaxone, and in those who have a severe penicillin allergy, oral doxycycline or azithromycin.Syphilis is thought to have infected 12 million additional people worldwide in 1999, with greater than 90% of cases in the developing world. After decreasing dramatically since the widespread availability of penicillin in the 1940s, rates of infection have increased since the turn of the millennium in many countries, often in combination with human immunodeficiency virus (HIV). This has been attributed partly to increased promiscuity, prostitution, decreasing use of condoms, and unsafe sexual practices among men who have sex with men. In 2015, Cuba became the first country in the world to eradicate syphilis.