The main pulmonary artery in adults: a controlled multicenter study
... and they have been reported in PH group 1 [29] including PH related to congenital heart disease [30], where patent ductus arteriosus is the most frequently reported underlying pathology of the MPA aneurysms [31,32], PH group 2, including acquired heart valve disease [20], and PH group 3 including ch ...
... and they have been reported in PH group 1 [29] including PH related to congenital heart disease [30], where patent ductus arteriosus is the most frequently reported underlying pathology of the MPA aneurysms [31,32], PH group 2, including acquired heart valve disease [20], and PH group 3 including ch ...
some aspects of left ventricular remodeling in patients with chronic
... eccentric hypertrophy of LV observed in 76.6% of patients and there by the beginning of the development of renal failure. Concentric hypertrophy with the most common in patients with CKD III-IV, and eccentric hypertrophy frequency increases with the progression of CKD. At a certain stage in the deve ...
... eccentric hypertrophy of LV observed in 76.6% of patients and there by the beginning of the development of renal failure. Concentric hypertrophy with the most common in patients with CKD III-IV, and eccentric hypertrophy frequency increases with the progression of CKD. At a certain stage in the deve ...
Gary J. Balady Jonathan Myers, Ross Arena, Barry Franklin, Ileana
... maintaining a high-quality clinical exercise testing laboratory for administering graded exercise tests to adults. Pediatric testing has been addressed separately.1 It is a revision of the 1995 American Heart Association (AHA) “Guidelines for Clinical Exercise Testing Laboratories”2 and is designed ...
... maintaining a high-quality clinical exercise testing laboratory for administering graded exercise tests to adults. Pediatric testing has been addressed separately.1 It is a revision of the 1995 American Heart Association (AHA) “Guidelines for Clinical Exercise Testing Laboratories”2 and is designed ...
The EP Show
... A major limitation of the the major ICD trials is that follow-up was only two to three years but the disease is a chronic one "The severity of the underlying heart disease is a moving target, and the sad reality is that the trajectory of the severity of heart disease is such that most patients over ...
... A major limitation of the the major ICD trials is that follow-up was only two to three years but the disease is a chronic one "The severity of the underlying heart disease is a moving target, and the sad reality is that the trajectory of the severity of heart disease is such that most patients over ...
Measuring central pulmonary pressures during exercise in COPD
... Haemodynamic assessment remains the gold standard in the diagnosis of cardiovascular and pulmonary vascular disease. In an effort to detect early and potentially more treatable pulmonary vascular disease [1, 2], and heart failure with preserved ejection fraction [3], there has been renewed interest ...
... Haemodynamic assessment remains the gold standard in the diagnosis of cardiovascular and pulmonary vascular disease. In an effort to detect early and potentially more treatable pulmonary vascular disease [1, 2], and heart failure with preserved ejection fraction [3], there has been renewed interest ...
4 Arrhythmias in Children and Young Adults Harinder R. Singh
... surgery for congenital heart disease (CHD), especially in patients with Mustard, Senning, and Fontan procedures (Fishberger 2001). Approximately 2/3 of all immediate posttransplant patients have SND (Jacquet et al. 1990). 4.1.3 Mechanism: In sinus node pause/arrest, there is a lack of discharge from ...
... surgery for congenital heart disease (CHD), especially in patients with Mustard, Senning, and Fontan procedures (Fishberger 2001). Approximately 2/3 of all immediate posttransplant patients have SND (Jacquet et al. 1990). 4.1.3 Mechanism: In sinus node pause/arrest, there is a lack of discharge from ...
Arrhythmia/Electrophysiology
... outcome of sports-related sudden death have not been assessed previously in the general population. Methods and Results—A prospective and comprehensive national survey was performed throughout France from 2005 to 2010, involving subjects 10 to 75 years of age. Case detection for sports-related sudde ...
... outcome of sports-related sudden death have not been assessed previously in the general population. Methods and Results—A prospective and comprehensive national survey was performed throughout France from 2005 to 2010, involving subjects 10 to 75 years of age. Case detection for sports-related sudde ...
Cardiac Hypertrophy: A Review on Pathogenesis and Treatment
... TNF-α increases oxidative stress in the myocardial cells by changing the mitochondrial redox state and membrane permeability transition pore opening, which ultimately leads to cardiac hypertrophy. [12, 44] G-protein coupled receptors (GPCRs) play an important role in the regulation of cardiac functi ...
... TNF-α increases oxidative stress in the myocardial cells by changing the mitochondrial redox state and membrane permeability transition pore opening, which ultimately leads to cardiac hypertrophy. [12, 44] G-protein coupled receptors (GPCRs) play an important role in the regulation of cardiac functi ...
30 Respiratory and Circulatory Systems
... Emphysema (EHM-fih-SEE-muh) is a lung disorder caused mainly by smoking. Over time, many alveoli are destroyed. This process gradually reduces the surface area for gas exchange, and not enough oxygen can enter the blood. People with advanced emphysema must use supplemental oxygen, but eventually the ...
... Emphysema (EHM-fih-SEE-muh) is a lung disorder caused mainly by smoking. Over time, many alveoli are destroyed. This process gradually reduces the surface area for gas exchange, and not enough oxygen can enter the blood. People with advanced emphysema must use supplemental oxygen, but eventually the ...
Implantation Techniques of Leads for Left Ventricular
... The first descriptions of beneficial effects of left ventricular (LV) or simultaneous LV and right ventricular (RV) pacing were published more than 35 years ago (Vagnini et al.,1967; Tyers et al.,1970; Gibson et al.,1971). In 1994 Cazeau published the first successful cases of biventricular pacing i ...
... The first descriptions of beneficial effects of left ventricular (LV) or simultaneous LV and right ventricular (RV) pacing were published more than 35 years ago (Vagnini et al.,1967; Tyers et al.,1970; Gibson et al.,1971). In 1994 Cazeau published the first successful cases of biventricular pacing i ...
Abnormal Echocardiogram
... this display is not truly one-dimensional. The M-mode presentation permits recording of amplitude and of the rate of motion of moving objects with great accuracy. The sampling rate is essentially 1000 pulses/sec. With the transducer placed along the left sternal border in approximately the third or ...
... this display is not truly one-dimensional. The M-mode presentation permits recording of amplitude and of the rate of motion of moving objects with great accuracy. The sampling rate is essentially 1000 pulses/sec. With the transducer placed along the left sternal border in approximately the third or ...
Chapter 12 The Circulatory System
... Elsevier items and derived items © 2008, 2004 by Mosby, Inc., an affiliate of Elsevier Inc. ...
... Elsevier items and derived items © 2008, 2004 by Mosby, Inc., an affiliate of Elsevier Inc. ...
Rapid Communications - Circulation Research
... function but also display a dominant-negative effect by partially inactivating the normal channel subunits encoded by the WT allele in heterozygous patients.16 –18 By contrast, mutations responsible for JLN syndrome have no pronounced dominant-negative effect but abolish the current in the homozygou ...
... function but also display a dominant-negative effect by partially inactivating the normal channel subunits encoded by the WT allele in heterozygous patients.16 –18 By contrast, mutations responsible for JLN syndrome have no pronounced dominant-negative effect but abolish the current in the homozygou ...
Comparison of Simultaneously Recorded Central and Peripheral
... The catheter-manometer system permitted immediately interchangeable recording with a capacitance* or strain-gage manometer. Both straingauge and capacitance manometer-catheter systems were optimally damped. The response of the straingauge manometer-catheter system to sine-wave pressure variations of ...
... The catheter-manometer system permitted immediately interchangeable recording with a capacitance* or strain-gage manometer. Both straingauge and capacitance manometer-catheter systems were optimally damped. The response of the straingauge manometer-catheter system to sine-wave pressure variations of ...
... failure in the presence of a normal or near-normal LV ejection fraction (greater than 40%–50%). It remains controversial whether measurements of diastolic function are necessary for the diagnosis of diastolic heart failure. Some insist that there must be hemodynamic (echocardiographic or catheteriza ...
Respiratory modulation of heart sound morphology - AJP
... of LV-SV (25). The opposed process occurs during expiration, in which RV-EDV and RV-SV decrease while LV-EDV and LV-SV increase. The effects of the respiratory cycle and intrathoracic pressure changes on cardiac function are well known clinically in the form of “pulsus paradoxus” as a sign of asthma ...
... of LV-SV (25). The opposed process occurs during expiration, in which RV-EDV and RV-SV decrease while LV-EDV and LV-SV increase. The effects of the respiratory cycle and intrathoracic pressure changes on cardiac function are well known clinically in the form of “pulsus paradoxus” as a sign of asthma ...
ESC Guidelines - Dansk Cardiologisk Selskab
... Associations: European Association for Cardiovascular Prevention & Rehabilitation (EACPR), European Association of Echocardiography (EAE), European Heart Rhythm Association (EHRA), European Association of Percutaneous Cardiovascular Interventions (EAPCI) Working Groups: Acute Cardiac Care, Cardiovas ...
... Associations: European Association for Cardiovascular Prevention & Rehabilitation (EACPR), European Association of Echocardiography (EAE), European Heart Rhythm Association (EHRA), European Association of Percutaneous Cardiovascular Interventions (EAPCI) Working Groups: Acute Cardiac Care, Cardiovas ...
experimental fluid mechanics of pulsatile artificial blood pumps
... Hemolysis, the destruction of red blood cells, and thrombosis, clot formation, must be avoided in artificial blood pumps to achieve long-term clinical success. The relationship of these events to the fluid mechanics, velocity, shear and wall shear rates, and turbulence is the major impetus for flow stu ...
... Hemolysis, the destruction of red blood cells, and thrombosis, clot formation, must be avoided in artificial blood pumps to achieve long-term clinical success. The relationship of these events to the fluid mechanics, velocity, shear and wall shear rates, and turbulence is the major impetus for flow stu ...
Severe Hypoglycemia in Type 2 Diabetes A Hospital
... economic impact and adverse effect on quality of life. The aim of this study was to assess the incidence of and risk factors for severe hypoglycemia among patients with type 2 diabetes. Methods We evaluated a cohort of 1195 patients with type 2 diabetes followed in the outpatient clinic of Mackay Me ...
... economic impact and adverse effect on quality of life. The aim of this study was to assess the incidence of and risk factors for severe hypoglycemia among patients with type 2 diabetes. Methods We evaluated a cohort of 1195 patients with type 2 diabetes followed in the outpatient clinic of Mackay Me ...
transfer of the heart pacemaker during juvenile development in the
... neurones, runs longitudinally in the midline of the inner surface of the dorsal heart wall. Fig. 2A–C shows morphological features of the heart of newly hatched juveniles. At this stage of development, the heart tube was approximately 1 mm in length and 0.1 mm wide and was suspended in the pericardi ...
... neurones, runs longitudinally in the midline of the inner surface of the dorsal heart wall. Fig. 2A–C shows morphological features of the heart of newly hatched juveniles. At this stage of development, the heart tube was approximately 1 mm in length and 0.1 mm wide and was suspended in the pericardi ...
AHA Scientific Statement
... Arm exercise testing is a useful alternative for diagnostic testing of patients with lower-extremity impairment caused by vascular, orthopedic, or neurological conditions. In addition, arm ergometry is helpful for performing occupational evaluations in patients whose work primarily involves the arms ...
... Arm exercise testing is a useful alternative for diagnostic testing of patients with lower-extremity impairment caused by vascular, orthopedic, or neurological conditions. In addition, arm ergometry is helpful for performing occupational evaluations in patients whose work primarily involves the arms ...
Heart Failure Induced by Perinatal Ablation of Cardiac Myosin Light
... Background: Germline knockout mice are invaluable in understanding the function of the targeted genes. Sometimes, however, unexpected phenotypes are encountered, due in part to the activation of compensatory mechanisms. Germline ablation of cardiac myosin light chain kinase (cMLCK) causes mild cardi ...
... Background: Germline knockout mice are invaluable in understanding the function of the targeted genes. Sometimes, however, unexpected phenotypes are encountered, due in part to the activation of compensatory mechanisms. Germline ablation of cardiac myosin light chain kinase (cMLCK) causes mild cardi ...
3. Cardiac Output
... sympathetic nervous system (Dual supply from both divisions of A.N.S) • The ventricles are mainly supplied by the sympathetic nervous system. There is very little Parasympathetic supply of the ventricles ...
... sympathetic nervous system (Dual supply from both divisions of A.N.S) • The ventricles are mainly supplied by the sympathetic nervous system. There is very little Parasympathetic supply of the ventricles ...
Ventriculoarterial Coupling in Normal and Failing Heart in Humans
... however, that the physiological control mechanisms indeed adopt this criterion for optimal coupling between the heart and artery under physiological circumstances in vivo. Another criterion for optimal coupling between an energy source and its load is the principle of economical fuel consumption, or ...
... however, that the physiological control mechanisms indeed adopt this criterion for optimal coupling between the heart and artery under physiological circumstances in vivo. Another criterion for optimal coupling between an energy source and its load is the principle of economical fuel consumption, or ...
... number and expressing it per square centimetre of tissue section as measured by planimetry. Although this method has been used frequently in the past, the most accurate way of quantifying numbers of pulmonary endocrine cells is to express them in terms of the total epithelial population (e.g. endocr ...
Coronary artery disease
Coronary artery disease (CAD), also known as ischemic heart disease (IHD), atherosclerotic heart disease, atherosclerotic cardiovascular disease, and coronary heart disease, is a group of diseases that includes: stable angina, unstable angina, myocardial infarction, and sudden coronary death. It is within the group of cardiovascular diseases of which it is the most common type. A common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck, or jaw. Occasionally it may feel like heartburn. Usually symptoms occur with exercise or emotional stress, last less than a few minutes, and gets better with rest. Shortness of breath may also occur and sometimes no symptoms are present. The first sign is occasionally a heart attack. Other complications include heart failure or an irregular heartbeat.Risk factors include: high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol, among others. Other risks include depression. The underlying mechanism involves atherosclerosis of the arteries of the heart. A number of tests may help with diagnoses including: electrocardiogram, cardiac stress testing, coronary computed tomographic angiography, and coronary angiogram, among others.Prevention is by eating a healthy diet, regular exercise, maintaining a healthy weight and not smoking. Sometimes medication for diabetes, high cholesterol, or high blood pressure are also used. There is limited evidence for screening people who are at low risk and do not have symptoms. Treatment involves the same measures as prevention. Additional medications such as antiplatelets including aspirin, beta blockers, or nitroglycerin may be recommended. Procedures such as percutaneous coronary intervention (PCI) or coronary artery bypass surgery (CABG) may be used in severe disease. In those with stable CAD it is unclear if PCI or CABG in addition to the other treatments improve life expectancy or decreases heart attack risk.In 2013 CAD was the most common cause of death globally, resulting in 8.14 million deaths (16.8%) up from 5.74 million deaths (12%) in 1990. The risk of death from CAD for a given age has decreased between 1980 and 2010 especially in the developed world. The number of cases of CAD for a given age has also decreased between 1990 and 2010. In the United States in 2010 about 20% of those over 65 had CAD, while it was present in 7% of those 45 to 64, and 1.3% of those 18 to 45. Rates are higher among men than women of a given age.