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No evidence for systolic or diastolic left ventricular dysfunction at rest
No evidence for systolic or diastolic left ventricular dysfunction at rest

... in the myocardium of patients with long-term diabetes including myocardial hypertrophy, perivascular and interstitial fibrosis, glycoprotein deposits and endothelial proliferation w25x. These changes seem to be more prominent in patients with diabetes plus hypertension than in patients with either d ...
A Healthy cholesterol
A Healthy cholesterol

... Your cholesterol can be measured by your doctor, who knows your family history. If a family member has high cholesterol, heart disease or has had a stroke, it’s really important you ask your doctor to do this test. You can do this on any visit. If your results show a blood cholesterol level greater ...
blood pressure
blood pressure

... against the inner walls of blood vessels anywhere in the cardiovascular system, although the term "blood pressure" usually refers to arterial pressure. ...
Cats` Silent Killer: Screening for cardiomyopathy in
Cats` Silent Killer: Screening for cardiomyopathy in

... the only way to characterize an arrhythmia accurately. Other changes on the ECG may give clues about the underlying etiology of cardiac disease, but an echocardiogram is needed for a specific diagnosis. Echocardiography—A complete echocardiographic evaluation allows for an assessment of cardiac stru ...
Four chamber right ventricular longitudinal strain versus right free
Four chamber right ventricular longitudinal strain versus right free

... function. Thus, we included consecutive patients with different degree of TR severity associated to left heart disease. ...
The Heart
The Heart

... • Mortality — 452,327 deaths in the United States in 2004 (one of every 5 deaths). • Incidence — 1,200,000 new and recurrent coronary attacks per year. • About 38 percent of people who experience a coronary attack in a given year die from it. ...
Efficacy of Two Streptokinase Formulations in Acute Myocardial
Efficacy of Two Streptokinase Formulations in Acute Myocardial

... the efficacy and success rate of a thrombolytic agent in bringing back the patency of vessels can be evaluated. As an example, angiography done within 90 minutes post-myocardial infarction is a very efficient way in assessing the efficacy of thrombolysis. As it is a time-consuming and ...
Exercise and Physical Activity in the Prevention and Treatment of
Exercise and Physical Activity in the Prevention and Treatment of

... average increase in HDL-C levels of 4.6% and reductions in triglyceride and LDL-C concentrations of 3.7% and 5.0%, respectively.15,16 The largest and most carefully controlled exercise trial, the HEalth, RIsk factors, exercise Training, And GEnetics (HERITAGE) study, included 675 normolipidemic subj ...
Risk Stratification and Outcome of Patients With
Risk Stratification and Outcome of Patients With

... (n=133, 31%), including a substantial proportion from noncardiac disease (n=54). Sixteen patients (3.7%) had HCMrelated mortality events (0.64%/y), including embolic stroke (n=6), progressive heart failure or transplantation (n=3), postoperative complications (n=2), and arrhythmic sudden death event ...
heart sounds - Donald Hudson Home
heart sounds - Donald Hudson Home

... • Anatomically they are located between the atria and the ventricles • They close because the ventricles contract • The Pulmonic and Aortic valves are opening and blood is being forced into the arteries ...
Physiology of cardiovascular system L5 Dr.Abdul
Physiology of cardiovascular system L5 Dr.Abdul

... the rate and parasympathetic stimulation decreasing it, heart rate can also be influenced by other factors:  Hormones, epinephrine and norepinephrine released from the adrenal medullae during exercise and stress increase both heart rate and contractility.  Ions, elevated levels of sodium and potas ...
Prognostic Value of Global Myocardial Performance Indices in Acute
Prognostic Value of Global Myocardial Performance Indices in Acute

... Downloaded From: http://publications.chestnet.org/pdfaccess.ashx?url=/data/journals/chest/22000/ on 05/07/2017 ...
4 Decisions Driving Growth - Croydon Health Services NHS Trust
4 Decisions Driving Growth - Croydon Health Services NHS Trust

... • typical history • physical signs • evidence of an underlying cause (12 lead ECG, CXR, echo) B-Natriuretic peptides: • Released by stretched ventricular myocytes • Homeostatic mechanism - decrease SVR, cause natriuresis (sodium and water loss) • N-terminal (NT-)proBNP has long half-life (good diagn ...
Revision Notes on Cardiovascular Examination: 1. On approaching
Revision Notes on Cardiovascular Examination: 1. On approaching

... Left or right thoracotomy scars in association with pulse on corresponding side If bilateral thoracotomy scars -- failure of one shunt and the need for second shunt procedure Central sternotomy scar indicates definitive repair carried out - Childmay not be cyanosed , but may still have right ventric ...
Exercise Training in Chronic Heart Failure
Exercise Training in Chronic Heart Failure

... Further, most studies show that in patients with CHF, arterial blood gases remain normal during a bout of exercise.17 Other explanations include a mismatch of pulmonary ventilation and perfusion leading to an increase in dead space, and/or weakness of respiratory muscles. While these might apply in ...
Images in Paediatric Cardiology
Images in Paediatric Cardiology

... of infants only.1 Cardiac hemangioma in infancy is extremely rare and resection of these tumors after prenatal diagnosis has been rarely reported.2 There have been approximately 40 reported cases of primary cardiac hemangiomas in current cardiac literature.3 McAllister reviewed 533 primary tumors an ...
Relationship of MRI delayed contrast enhancement to irreversible
Relationship of MRI delayed contrast enhancement to irreversible

... ischemic event are strong predictors of patient outcome, and interventions that reduce injury significantly improve prognosis.1 MRI contrast enhancement observed early (tens of seconds) after contrast is affected by large-artery patency2,3 and microvascular obstruction4,5 and is thought to relate to ...
New conduction defects and pacemaker implantation after heart
New conduction defects and pacemaker implantation after heart

... 0%, p= 0.008) and 90 days (17% vs. 1.8% p= 0.01) posttransplantation with the bicaval technique. However, variable results were attained from studies comparing bicaval and biatrial anastomosis for regarding a pacemaker need. For instance, in a study of bicaval anastomosis, pacing was not required in ...
design and subjects - Nnamdi Azikiwe University
design and subjects - Nnamdi Azikiwe University

... Pre-eclampsia is a pregnancy-specific condition that increases maternal and infant mortality and morbidity. It is diagnosed based on a triad of hypertension, significant proteinuria and rapidly increasing oedema during gestation (Ganiyu et al., 2006) Most women with the condition are symptom free, a ...
Right atrium
Right atrium

... HEART RATE More often, when the heart beats faster, each contraction of the left ventricle takes place so rapidly that it has little time full and squeezes out much less blood than usual. This decreases the arterial blood volume and therefore blood pressure decreases even though heart rate has incr ...
Cardiovascular Registries - Circulation: Cardiovascular Interventions
Cardiovascular Registries - Circulation: Cardiovascular Interventions

... There is no question that there are many positive attributes associated with prospective observational registries, but there are clearly shortcomings as well. One is the growing number of registries. New registries are being added every few months. At Brigham and Women’s Hosptial, we currently parti ...
Impact of Severe Tricuspid Regurgitation on Long Term Survival
Impact of Severe Tricuspid Regurgitation on Long Term Survival

... Background: Tricuspid regurgitation (TR) is a common echocardiographic finding, which often accompanies left sided valve disease. Data on mortality and morbidity in patients with severe TR are limited. Objectives: We sought to assess the outcome of patients with severe TR with the hypothesis that si ...
Examination of the Heart2
Examination of the Heart2

... does not provide useful information. ...
11 Heart Rate BP Exercise
11 Heart Rate BP Exercise

... 6. Recovery time has been shown to correlate with degree of physical fitness. How does your/the subject’s recovery rate compare to that of your classmates? Is this what you expected? ...
American Ginseng Acutely Regulates Contractile Function of the Heart
American Ginseng Acutely Regulates Contractile Function of the Heart

... Li et al. reported that ginsenoside-induced vasorelaxation also involves Ca2+ activated K+ channels in vascular smooth muscle cells Korean red ginseng can improve the vascular endothelial dysfunction in patients with hypertension possibly through increasing NO Single channel analysis on calcium chan ...
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Coronary artery disease



Coronary artery disease (CAD), also known as ischemic heart disease (IHD), atherosclerotic heart disease, atherosclerotic cardiovascular disease, and coronary heart disease, is a group of diseases that includes: stable angina, unstable angina, myocardial infarction, and sudden coronary death. It is within the group of cardiovascular diseases of which it is the most common type. A common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck, or jaw. Occasionally it may feel like heartburn. Usually symptoms occur with exercise or emotional stress, last less than a few minutes, and gets better with rest. Shortness of breath may also occur and sometimes no symptoms are present. The first sign is occasionally a heart attack. Other complications include heart failure or an irregular heartbeat.Risk factors include: high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol, among others. Other risks include depression. The underlying mechanism involves atherosclerosis of the arteries of the heart. A number of tests may help with diagnoses including: electrocardiogram, cardiac stress testing, coronary computed tomographic angiography, and coronary angiogram, among others.Prevention is by eating a healthy diet, regular exercise, maintaining a healthy weight and not smoking. Sometimes medication for diabetes, high cholesterol, or high blood pressure are also used. There is limited evidence for screening people who are at low risk and do not have symptoms. Treatment involves the same measures as prevention. Additional medications such as antiplatelets including aspirin, beta blockers, or nitroglycerin may be recommended. Procedures such as percutaneous coronary intervention (PCI) or coronary artery bypass surgery (CABG) may be used in severe disease. In those with stable CAD it is unclear if PCI or CABG in addition to the other treatments improve life expectancy or decreases heart attack risk.In 2013 CAD was the most common cause of death globally, resulting in 8.14 million deaths (16.8%) up from 5.74 million deaths (12%) in 1990. The risk of death from CAD for a given age has decreased between 1980 and 2010 especially in the developed world. The number of cases of CAD for a given age has also decreased between 1990 and 2010. In the United States in 2010 about 20% of those over 65 had CAD, while it was present in 7% of those 45 to 64, and 1.3% of those 18 to 45. Rates are higher among men than women of a given age.
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