Pulmonary Hypertension - American Thoracic Society
... overall survival of patients with idiopathic PAH has doubled with these drugs, and quality of life has markedly improved. In addition to the calcium channel blockers, three other classes of vasoactive drugs are used to treat pulmonary hypertension: endothelin receptor antagonists, phosphodiesterase- ...
... overall survival of patients with idiopathic PAH has doubled with these drugs, and quality of life has markedly improved. In addition to the calcium channel blockers, three other classes of vasoactive drugs are used to treat pulmonary hypertension: endothelin receptor antagonists, phosphodiesterase- ...
Congenitally corrected transposition of the great arteries: clues for
... Congenitally corrected transposition of the great arteries (ccTGA) is an uncommon cardiac defect characterized by the atria connecting with the anatomically discordant ventricles and the ventricles connecting with discordant and transposed great arteries. Parallel vessels are evident in corrected TG ...
... Congenitally corrected transposition of the great arteries (ccTGA) is an uncommon cardiac defect characterized by the atria connecting with the anatomically discordant ventricles and the ventricles connecting with discordant and transposed great arteries. Parallel vessels are evident in corrected TG ...
Heart size-independent analysis of myocardial
... crystal placed on the anterior free wall to measure instantaneous wall thickness. Highly linear -⑀ relations were obtained in control (n ⫽ 7) and hypertrophied mice produced by 7 days of transverse aortic constriction (TAC; n ⫽ 13). Administration of dobutamine in control mice significantly increas ...
... crystal placed on the anterior free wall to measure instantaneous wall thickness. Highly linear -⑀ relations were obtained in control (n ⫽ 7) and hypertrophied mice produced by 7 days of transverse aortic constriction (TAC; n ⫽ 13). Administration of dobutamine in control mice significantly increas ...
The role of the three vessels and trachea view (3VT) in the diagnosis
... Antenatal diagnosis of congenital anomalies of the fetal heart is important for proper perinatal and neonatal management1,2 . The four-chamber view is the basis of the cardiac scan in a screening examination for congenital heart disease (CHD). The technique is simple and easy to reproduce and with c ...
... Antenatal diagnosis of congenital anomalies of the fetal heart is important for proper perinatal and neonatal management1,2 . The four-chamber view is the basis of the cardiac scan in a screening examination for congenital heart disease (CHD). The technique is simple and easy to reproduce and with c ...
Effect of Training Mode on Post-Exercise Heart Rate Recovery of
... markers of overall fitness and training status, including overtraining (10), however, HRRec is the most easily applicable method for athletic training as it requires no special equipment. Results of previous studies suggest that autonomic adaptation to exercise vary depending on training mode and t ...
... markers of overall fitness and training status, including overtraining (10), however, HRRec is the most easily applicable method for athletic training as it requires no special equipment. Results of previous studies suggest that autonomic adaptation to exercise vary depending on training mode and t ...
Exercise, the Athlete`s Heart, and Sudden Cardiac Death
... contraction and altered sympathetic/parasympathetic balance heralds an abrupt reduction in venous return, with subsequent transient cerebral hypoperfusion. This form of syncope can often be avoided by instituting an active cool-down period after vigorous exercise, with care being taken to maintain a ...
... contraction and altered sympathetic/parasympathetic balance heralds an abrupt reduction in venous return, with subsequent transient cerebral hypoperfusion. This form of syncope can often be avoided by instituting an active cool-down period after vigorous exercise, with care being taken to maintain a ...
Netherlands Heart Journal Supplements
... equally. Purpose: The prognostic value is one of the most robust features of non-invasive cardiac imaging. However, comparison of prognosis between all available tests and the influence of the pretest probability has not been explored before in a single study. Methods: MEDLINE, EMBASE and Cochrane L ...
... equally. Purpose: The prognostic value is one of the most robust features of non-invasive cardiac imaging. However, comparison of prognosis between all available tests and the influence of the pretest probability has not been explored before in a single study. Methods: MEDLINE, EMBASE and Cochrane L ...
2016 ESC Position Paper on cancer treatments and cardiovascular
... new guidelines and position papers produced by task forces, expert groups or consensus panels. The Committee is also responsible for the endorsement process of these documents. The CPG documents undergo extensive review by the CPG and external experts. After appropriate revisions these documents are ...
... new guidelines and position papers produced by task forces, expert groups or consensus panels. The Committee is also responsible for the endorsement process of these documents. The CPG documents undergo extensive review by the CPG and external experts. After appropriate revisions these documents are ...
Cardiac macrophages and their role in ischaemic heart disease
... During embryogenesis, the spleen and liver are sites of haematopoiesis, but these organs cease haematopoietic activity, at least in the steady state, after birth. The monocyte release from the spleen is independent of CCR2 but caused by angiotensin-2 signalling.17 Splenic monocyte mobilization can b ...
... During embryogenesis, the spleen and liver are sites of haematopoiesis, but these organs cease haematopoietic activity, at least in the steady state, after birth. The monocyte release from the spleen is independent of CCR2 but caused by angiotensin-2 signalling.17 Splenic monocyte mobilization can b ...
Pathogenesis and pathophysiology of aortic valve stenosis in adults
... tion of asymptomatic phase varies widely among individuals. A recent study showed that the prob‑ ability of living 5 years without cardiovascular events is below 50% in asymptomatic patients. Predictors of rapid progression of valve disease include age under 50 years, coronary artery dis‑ ease, elev ...
... tion of asymptomatic phase varies widely among individuals. A recent study showed that the prob‑ ability of living 5 years without cardiovascular events is below 50% in asymptomatic patients. Predictors of rapid progression of valve disease include age under 50 years, coronary artery dis‑ ease, elev ...
Point of View The Long QT Interval Syndrome
... with cardiac events, the number of cardiac events per patient, and the number of patients with five or more cardiac events all decreased significantly. However, there still were seven (8%) sudden deaths, reducing the 5-year survival to 94%. ...
... with cardiac events, the number of cardiac events per patient, and the number of patients with five or more cardiac events all decreased significantly. However, there still were seven (8%) sudden deaths, reducing the 5-year survival to 94%. ...
Left Ventricular End-Diastolic Pressure- Volume
... et al.6 Only one patient, with the nonobstructive form ofthe disease, had an elevation of the ...
... et al.6 Only one patient, with the nonobstructive form ofthe disease, had an elevation of the ...
The Role of the Heart in Hypertension
... infrequently elevated in various types of hypertension, how far could one label as cardiogenic the many types of hyperkinetic hypertension? [ 10, 181. The question is particularly pertinent since increased cardiac action is not the only, and possibly not even the most frequent, cause of a high outpu ...
... infrequently elevated in various types of hypertension, how far could one label as cardiogenic the many types of hyperkinetic hypertension? [ 10, 181. The question is particularly pertinent since increased cardiac action is not the only, and possibly not even the most frequent, cause of a high outpu ...
AHA/ACS/AUA Science Advisory
... Alterations in body composition appear to be primarily an early adverse effect, with most of the treatment-related changes in fat and lean body mass apparent within the first few months of therapy.21,22 ADT also increases serum cholesterol and triglyceride levels.18,23 In a prospective 12-month stud ...
... Alterations in body composition appear to be primarily an early adverse effect, with most of the treatment-related changes in fat and lean body mass apparent within the first few months of therapy.21,22 ADT also increases serum cholesterol and triglyceride levels.18,23 In a prospective 12-month stud ...
Developmental anatomy of the heart
... where the exact staging protocol that has been followed is not known, it is equally important to point that out when reporting on data based on these tissues. As more and more clinical imaging techniques are now being adapted for use in studies on mouse models [e.g., MRI, ultrasound (10)], it is imp ...
... where the exact staging protocol that has been followed is not known, it is equally important to point that out when reporting on data based on these tissues. As more and more clinical imaging techniques are now being adapted for use in studies on mouse models [e.g., MRI, ultrasound (10)], it is imp ...
2016 ESC Cardio oncology
... treatments that may have cardiotoxic effects, as well as in the evaluation of cardiac events related to such drugs. This document reviews the different steps in cardiovascular monitoring and decision-making before, during and after cancer treatment with potential cardiovascular side effects. Althoug ...
... treatments that may have cardiotoxic effects, as well as in the evaluation of cardiac events related to such drugs. This document reviews the different steps in cardiovascular monitoring and decision-making before, during and after cancer treatment with potential cardiovascular side effects. Althoug ...
Percutaneous intracardiac baffle stenting after a
... pulmonary venous return of the entire right lung to the inferior vena cava (IVC), one of the hepatic veins, or the vena porta [1]. The name is based on the typical appearance of a curvilinear shadow adjacent to the right heart border that looks like a curved Turkish sword [2]. It is not uncommon tha ...
... pulmonary venous return of the entire right lung to the inferior vena cava (IVC), one of the hepatic veins, or the vena porta [1]. The name is based on the typical appearance of a curvilinear shadow adjacent to the right heart border that looks like a curved Turkish sword [2]. It is not uncommon tha ...
undergoing valve replacement Mitral regurgitation in patients with
... -3More severe MR is far from exceptional. Ruel et al. reported that ≥ grade 2/4 functional MR was found preoperatively in 13% of 848 patients undergoing isolated AVR.[8] Barreiro et al. reported moderate MR in 17% of 408 patients aged ≥70 y undergoing isolated AVR.[7] In this population, MR was isch ...
... -3More severe MR is far from exceptional. Ruel et al. reported that ≥ grade 2/4 functional MR was found preoperatively in 13% of 848 patients undergoing isolated AVR.[8] Barreiro et al. reported moderate MR in 17% of 408 patients aged ≥70 y undergoing isolated AVR.[7] In this population, MR was isch ...
Aldosterone Receptor Antagonist and Heart Failure Following Acute
... post-MI animal model. 28 Given the significant role of aldosterone in post-MI pathophysiology, its blockade with agents such as spironolactone or eplerenone beyond ACE inhibition is essential for continued benefit. The endothelium plays an important role in regulating vascular tone, platelet aggrega ...
... post-MI animal model. 28 Given the significant role of aldosterone in post-MI pathophysiology, its blockade with agents such as spironolactone or eplerenone beyond ACE inhibition is essential for continued benefit. The endothelium plays an important role in regulating vascular tone, platelet aggrega ...
Implantable Ventricular Assist Devices and Total
... Thoratec, Columbia University, and the National Institutes of Health. The randomized trial found that patients with end-stage heart failure who are not candidates for cardiac transplantation have significantly better survival on a VAD compared with treatment by optimal medical therapy. Median surviv ...
... Thoratec, Columbia University, and the National Institutes of Health. The randomized trial found that patients with end-stage heart failure who are not candidates for cardiac transplantation have significantly better survival on a VAD compared with treatment by optimal medical therapy. Median surviv ...
Echocardiographic assessment of systemic cardiac
... to structure this research, which is classified as a descriptive, prospective and applied study. A reference group was formed through the technique of systematic probability sampling in order to conduct the contrasting process. It was formed by supposedly healthy children of age and weight similar t ...
... to structure this research, which is classified as a descriptive, prospective and applied study. A reference group was formed through the technique of systematic probability sampling in order to conduct the contrasting process. It was formed by supposedly healthy children of age and weight similar t ...
Influence of sibutramine on heart rate in obese patients: systematic
... in heart rate occurs through the reduction in diastolic period, where occurs blood flow to the coronary arteries. We also know that some cardiac arrhythmias may be triggered by a persistent increase in heart rate. Given this, we must be vigilant in prescribing sibutramine because of its sympathomime ...
... in heart rate occurs through the reduction in diastolic period, where occurs blood flow to the coronary arteries. We also know that some cardiac arrhythmias may be triggered by a persistent increase in heart rate. Given this, we must be vigilant in prescribing sibutramine because of its sympathomime ...
E lectrocardiographic criteria for vagotonia—validation with
... has been an attenuation of the parasympathetic blocking capacity of atropine in the 15 min after the end of venous infusion. Actually, the CVT index values tended to 1.00, 5 min after the end of atropine infusion, and thus continued until 90 min after the infusion. Therefore, the moment we decided t ...
... has been an attenuation of the parasympathetic blocking capacity of atropine in the 15 min after the end of venous infusion. Actually, the CVT index values tended to 1.00, 5 min after the end of atropine infusion, and thus continued until 90 min after the infusion. Therefore, the moment we decided t ...
Cardiovascular β-adrenergic signaling Maturation and programming effects of hypoxia in a
... desensitization/downregulation mechanisms. Hypoxia quite commonly occurs in utero and it is well known that prenatal insults, like malnutrition or hypoxia, are coupled to an increased risk of developing adult cardiovascular disease. This is referred to as developmental programming and constitutes an ...
... desensitization/downregulation mechanisms. Hypoxia quite commonly occurs in utero and it is well known that prenatal insults, like malnutrition or hypoxia, are coupled to an increased risk of developing adult cardiovascular disease. This is referred to as developmental programming and constitutes an ...
Coronary artery disease
Coronary artery disease (CAD), also known as ischemic heart disease (IHD), atherosclerotic heart disease, atherosclerotic cardiovascular disease, and coronary heart disease, is a group of diseases that includes: stable angina, unstable angina, myocardial infarction, and sudden coronary death. It is within the group of cardiovascular diseases of which it is the most common type. A common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck, or jaw. Occasionally it may feel like heartburn. Usually symptoms occur with exercise or emotional stress, last less than a few minutes, and gets better with rest. Shortness of breath may also occur and sometimes no symptoms are present. The first sign is occasionally a heart attack. Other complications include heart failure or an irregular heartbeat.Risk factors include: high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol, among others. Other risks include depression. The underlying mechanism involves atherosclerosis of the arteries of the heart. A number of tests may help with diagnoses including: electrocardiogram, cardiac stress testing, coronary computed tomographic angiography, and coronary angiogram, among others.Prevention is by eating a healthy diet, regular exercise, maintaining a healthy weight and not smoking. Sometimes medication for diabetes, high cholesterol, or high blood pressure are also used. There is limited evidence for screening people who are at low risk and do not have symptoms. Treatment involves the same measures as prevention. Additional medications such as antiplatelets including aspirin, beta blockers, or nitroglycerin may be recommended. Procedures such as percutaneous coronary intervention (PCI) or coronary artery bypass surgery (CABG) may be used in severe disease. In those with stable CAD it is unclear if PCI or CABG in addition to the other treatments improve life expectancy or decreases heart attack risk.In 2013 CAD was the most common cause of death globally, resulting in 8.14 million deaths (16.8%) up from 5.74 million deaths (12%) in 1990. The risk of death from CAD for a given age has decreased between 1980 and 2010 especially in the developed world. The number of cases of CAD for a given age has also decreased between 1990 and 2010. In the United States in 2010 about 20% of those over 65 had CAD, while it was present in 7% of those 45 to 64, and 1.3% of those 18 to 45. Rates are higher among men than women of a given age.