![Samuel Frazer Sears Jr., Ph.D. PERSONAL INFORMATION East Carolina University](http://s1.studyres.com/store/data/008481418_1-73e479989bc4de062952f7f6a4a7d9ab-300x300.png)
Samuel Frazer Sears Jr., Ph.D. PERSONAL INFORMATION East Carolina University
... cardiac arrest care and the underutilization of effective therapies. American Heart Journal, 160, 605618. 37) Irvine, J., Firestone, J., Ong, L., Cribbie, R., Dorian, P., Harris, L., Ritvo, P., Katz, J., Newman, D., Cameron, D., Johnson, S., Bilanovic, A., Hill, A., O’Donnell, S., & Sears, S.F. (201 ...
... cardiac arrest care and the underutilization of effective therapies. American Heart Journal, 160, 605618. 37) Irvine, J., Firestone, J., Ong, L., Cribbie, R., Dorian, P., Harris, L., Ritvo, P., Katz, J., Newman, D., Cameron, D., Johnson, S., Bilanovic, A., Hill, A., O’Donnell, S., & Sears, S.F. (201 ...
A Cure for the Code Blues? Vasopressin, Steroid and Epinephrine
... i. Activation of cytokines, endotoxins, and reactive species after CA ii. Inflammatory response further damages ischemic organs a. Compounds neurologic damage b. Cytokines associated with mortality and unfavorable neurologic outcomes iii. Normal physiologic response to cytokines is stimulation of co ...
... i. Activation of cytokines, endotoxins, and reactive species after CA ii. Inflammatory response further damages ischemic organs a. Compounds neurologic damage b. Cytokines associated with mortality and unfavorable neurologic outcomes iii. Normal physiologic response to cytokines is stimulation of co ...
Pulmonary hypertension caused by pulmonary venous hypertension
... pulmonary venous pressure on PVR; (4) mechanical forces, especially increased wall stress, as the putative proximate cause of increased PVR with PVH; and (5) issues related to evaluating pharmacologic therapy aimed at reducing PVHPH. The effect of PVH on lung water is an important but somewhat disti ...
... pulmonary venous pressure on PVR; (4) mechanical forces, especially increased wall stress, as the putative proximate cause of increased PVR with PVH; and (5) issues related to evaluating pharmacologic therapy aimed at reducing PVHPH. The effect of PVH on lung water is an important but somewhat disti ...
Echocardiographic Evaluation Before Bidirectional Glenn Operation
... A total of 207 patients underwent BDG at Children’s Hospital Boston from January 2004 through April 2008. From this population, 130 patients who had both pre-BDG echo and catheterization performed within 60 days of surgery were included. The majority of exclusions were for lack of digital catheteriz ...
... A total of 207 patients underwent BDG at Children’s Hospital Boston from January 2004 through April 2008. From this population, 130 patients who had both pre-BDG echo and catheterization performed within 60 days of surgery were included. The majority of exclusions were for lack of digital catheteriz ...
The Sequence of Retrograde Atrial Activation in the Canine Heart
... The relationship of P-wave polarity and morphology in leads II, III, and aVF to the sequence of atrial activation was studied in the canine heart when the atria were paced from the region of the sinus node or the posterior-inferior left atrium and when retrograde activation of the atria occurred wit ...
... The relationship of P-wave polarity and morphology in leads II, III, and aVF to the sequence of atrial activation was studied in the canine heart when the atria were paced from the region of the sinus node or the posterior-inferior left atrium and when retrograde activation of the atria occurred wit ...
Haemodynamics in Essential Hypertension
... Lund-Johansen, 1977; Weiss, Safar, London, Simon, Levenson & Milliez, 1978; Julius, Quadir & Gajendragadkar, 1979). Only two include strictly untreated patients and have been performed with the same experimental conditions at both studies. In our series (Lund-Johansen, 1977, 1979a) 77 patients who h ...
... Lund-Johansen, 1977; Weiss, Safar, London, Simon, Levenson & Milliez, 1978; Julius, Quadir & Gajendragadkar, 1979). Only two include strictly untreated patients and have been performed with the same experimental conditions at both studies. In our series (Lund-Johansen, 1977, 1979a) 77 patients who h ...
Effects of calcium, parathyroid hormone and
... It would thus seem reasonable to assume that uremic cardiomyopathy is related at least partially to secondary hyperparathyroidism and that HD-induced acute changes in serum calcium regulate LV function and electrical stability during treatment. The fact that patients with primary hyperparathyroidism ...
... It would thus seem reasonable to assume that uremic cardiomyopathy is related at least partially to secondary hyperparathyroidism and that HD-induced acute changes in serum calcium regulate LV function and electrical stability during treatment. The fact that patients with primary hyperparathyroidism ...
Congenital diaphragmatic hernia with concurrent aplasia of the
... A large ovoid opening located in the left dorsolateral part of the diaphragm was observed (Fig. 1a, and b), affecting the muscular and the tendinous components. Measuring approximately 20 × 15 cm, the foramen had a regular rounded, smooth shape, was firm, with no signs of hemorrhage (Fig. 1b). Throu ...
... A large ovoid opening located in the left dorsolateral part of the diaphragm was observed (Fig. 1a, and b), affecting the muscular and the tendinous components. Measuring approximately 20 × 15 cm, the foramen had a regular rounded, smooth shape, was firm, with no signs of hemorrhage (Fig. 1b). Throu ...
Bundle Branch Block and Benefit from Cardiac Resynchronization
... experiencing shortness of breath, fatigue, edema, and a reduced capacity to perform normal daily activities. LV dilation in heart failure can be caused by multiple factors, including an abnormal electrical conduction in the hearts’ ventricles. In normal conduction, the electrical wave front starts a ...
... experiencing shortness of breath, fatigue, edema, and a reduced capacity to perform normal daily activities. LV dilation in heart failure can be caused by multiple factors, including an abnormal electrical conduction in the hearts’ ventricles. In normal conduction, the electrical wave front starts a ...
For Use With Mechanical Circulatory Assist Devices
... 78-year-old male. There is no tissue attachment to either surface of the PRECLUDE® Pericardial Membrane. Occasional clusters of red blood cells, fibrinous strands and collagen fibers are observed at the interface. Proteinaceous material is observed within the interstices of the implant. There is no ...
... 78-year-old male. There is no tissue attachment to either surface of the PRECLUDE® Pericardial Membrane. Occasional clusters of red blood cells, fibrinous strands and collagen fibers are observed at the interface. Proteinaceous material is observed within the interstices of the implant. There is no ...
Print - Circulation
... wedge pressure were made immediately before and after the wedge angiogram. Any contrast remaining in the radiographic field after flushing and withdrawing the catheter was recorded as a stain. One to five separate wedge angiograms in different positions were performed in each patient; a greater numb ...
... wedge pressure were made immediately before and after the wedge angiogram. Any contrast remaining in the radiographic field after flushing and withdrawing the catheter was recorded as a stain. One to five separate wedge angiograms in different positions were performed in each patient; a greater numb ...
The Fontan circulation after 45 years: update in physiology
... different and extreme loading conditions that can cause structural remodelling and cardiac dysfunction at many levels. During fetal life and the initial palliation, a single ventricle is volume overloaded (250%–350% of normal for body surface area (BSA) which will lead to ventricular overgrowth, ecc ...
... different and extreme loading conditions that can cause structural remodelling and cardiac dysfunction at many levels. During fetal life and the initial palliation, a single ventricle is volume overloaded (250%–350% of normal for body surface area (BSA) which will lead to ventricular overgrowth, ecc ...
Solutions for Electrocardiograph and Heart Rate Monitor Applications
... field, such as biomedical engineers or doctors, or for people who want to know more about the operation of heart rate monitors and electrocardiograph devices. ...
... field, such as biomedical engineers or doctors, or for people who want to know more about the operation of heart rate monitors and electrocardiograph devices. ...
The Prognostic Value of Left Atrial Peak Reservoir Strain in Acute
... analyzed according to GLS quartiles, using Cochran-Armitage trend test for categorical variables and ANOVA for continuous variables. All tests were 2-sided, and statistical significance was defined as P<0.05. Interobserver and intraobserver reproducibility of PALS and GLS was assessed in 20 randomly ...
... analyzed according to GLS quartiles, using Cochran-Armitage trend test for categorical variables and ANOVA for continuous variables. All tests were 2-sided, and statistical significance was defined as P<0.05. Interobserver and intraobserver reproducibility of PALS and GLS was assessed in 20 randomly ...
Pericardial Disease
... Historically, the most common cause of chronic pericarditis with constriction was tuberculous pericarditis. In developing nations, this remains a potential etiology. In the United States, however, this diagnosis is now rare; more likely causes include past episodes of viral or purulent pericarditis, ...
... Historically, the most common cause of chronic pericarditis with constriction was tuberculous pericarditis. In developing nations, this remains a potential etiology. In the United States, however, this diagnosis is now rare; more likely causes include past episodes of viral or purulent pericarditis, ...
Syncope Iowa State University
... perfusion. Syncope occurs when cerebral blood flow falls below 30–50% of normal. Symptoms of pre-syncope can occur with less severe hemodynamic changes.3 Syncope in dogs and cats, is often associated with excitement or exertion, when there is an increased demand for cardiac output and oxygenation.2, ...
... perfusion. Syncope occurs when cerebral blood flow falls below 30–50% of normal. Symptoms of pre-syncope can occur with less severe hemodynamic changes.3 Syncope in dogs and cats, is often associated with excitement or exertion, when there is an increased demand for cardiac output and oxygenation.2, ...
TRANSCATHETER AORTIC VALVE IMPLANTATION: REVIEW AND
... was initiated in 1985, with the introduction of balloon aortic valvuloplasty.6-8 In 1986, Alain Cribier reported on balloon aortic valvuloplasty carried out in three elderly patients with acquired severe aortic valve stenosis. The transvalvular systolic pressure gradient was considerably decreased a ...
... was initiated in 1985, with the introduction of balloon aortic valvuloplasty.6-8 In 1986, Alain Cribier reported on balloon aortic valvuloplasty carried out in three elderly patients with acquired severe aortic valve stenosis. The transvalvular systolic pressure gradient was considerably decreased a ...
Disclaimer
... commonly used (21) to supplement the resting ECG. The QT interval changes with exercise are impacted by both HR changes and the neurohumoral responses to exercise. Many formulae have been devised to attempt HR correction, but none is perfect and all have been found to have specific limitations (2). ...
... commonly used (21) to supplement the resting ECG. The QT interval changes with exercise are impacted by both HR changes and the neurohumoral responses to exercise. Many formulae have been devised to attempt HR correction, but none is perfect and all have been found to have specific limitations (2). ...
Paper - Journal of American Science
... Abstract: The cardioprotective effects of melatonin are consistent with its ability to scavenge free radical. However free radicals are considered as preconditioning factors, helping the heart to withstand consequent attacks of ischemic reperfusion injury. So, this study aimed to clarify whether mel ...
... Abstract: The cardioprotective effects of melatonin are consistent with its ability to scavenge free radical. However free radicals are considered as preconditioning factors, helping the heart to withstand consequent attacks of ischemic reperfusion injury. So, this study aimed to clarify whether mel ...
Importance of Atrial Flutter Isthmus in Postoperative Intra
... the 6 typical or reverse typical atrial flutters for which bidirectional isthmus block could be demonstrated, only 1 recurred, whereas of the 2 flutters for which bidirectional block could not be demonstrated, both recurred (Table 2). Five patients had attempted repeat ablation that was successful i ...
... the 6 typical or reverse typical atrial flutters for which bidirectional isthmus block could be demonstrated, only 1 recurred, whereas of the 2 flutters for which bidirectional block could not be demonstrated, both recurred (Table 2). Five patients had attempted repeat ablation that was successful i ...
Correlation of Atrial Natriuretic Peptide and Cyclic
... reported earlier, the interassay CV was 12.2% (8). The assays of atrial natriuretic peptide and cGMP plasma concentrations were performed independently in two different laboratories without knowing the donor's health status or ventricular function. Patients and controls A total of 50 individuals, co ...
... reported earlier, the interassay CV was 12.2% (8). The assays of atrial natriuretic peptide and cGMP plasma concentrations were performed independently in two different laboratories without knowing the donor's health status or ventricular function. Patients and controls A total of 50 individuals, co ...
Cardiomyocyte proliferation in cardiac development and regeneration
... underlying the regenerative capacity of these species. A wide variety of experiments have demonstrated that naturally occurring heart regeneration relies on cardiomyocyte proliferation. Thus, major efforts have been invested to induce proliferation of mammalian cardiomyocytes in order to improve car ...
... underlying the regenerative capacity of these species. A wide variety of experiments have demonstrated that naturally occurring heart regeneration relies on cardiomyocyte proliferation. Thus, major efforts have been invested to induce proliferation of mammalian cardiomyocytes in order to improve car ...
by Angiotensin II - Circulation Research
... Although the role of angiotensin II (Ang II) in the pathogenesis and progression of the failing heart is uncertain, previous reports have suggested that myocyte injury may be a component in this process. In this study, we investigated this possibility in more detail. Cardiotoxic effects of nonacutel ...
... Although the role of angiotensin II (Ang II) in the pathogenesis and progression of the failing heart is uncertain, previous reports have suggested that myocyte injury may be a component in this process. In this study, we investigated this possibility in more detail. Cardiotoxic effects of nonacutel ...
Cardiac surgery
![](https://commons.wikimedia.org/wiki/Special:FilePath/Coronary_artery_bypass_surgery_Image_657B-PH.jpg?width=300)
Cardiovascular (heart) surgery is surgery on the heart or great vessels performed by cardiac surgeons. Frequently, it is done to treat complications of ischemic heart disease (for example, coronary artery bypass grafting), correct congenital heart disease, or treat valvular heart disease from various causes including endocarditis, rheumatic heart disease and atherosclerosis. It also includes heart transplantation.