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The Prognostic Value of T Wave Amplitude in Lead aVR in Males
The Prognostic Value of T Wave Amplitude in Lead aVR in Males

... From the National Heart Centre, Singapore; and † Palo Alto Veterans Affairs Health Care System and Stanford University School of Medicine, Palo Alto, CA Background: Since there is an uncertainty regarding which of the 12 leads provides the most information, we investigated the association between re ...
A novel transgenic rabbit model of a long QT syndrome caused by a
A novel transgenic rabbit model of a long QT syndrome caused by a

... potassium channel, the presence of KCNE1 is required to reproduce the kinetic properties of the native IKs channel (Sanguinetti et al. 1996). IKs the slowly activating cardiac potassium current is an important determinant of myocardial repolarization. KCNE1 also known as Mink was the first among the ...
Catheter Ablation for Ventricular Tachycardia
Catheter Ablation for Ventricular Tachycardia

... You will be returned to the ward where you were admitted. It is possible that you may not remember anything from the operating room and might only wake up fully when you are back on the ward. This is normal. The person who accompanied you to the hospital can visit you as soon as you get back to the ...
S2 File.
S2 File.

... surgeons determine the size of the valve graft in situ using a measuring tool („sizer“) on the open heart. A “patient-prothesis-mismatch“ can result in elevated pressure gradients and in paravalvular leakage with suitable regurgitation, which new studies identified as negative prognostic factors. In ...
Deteriorating Patients With Chronic
Deteriorating Patients With Chronic

... COPD referred to the rehabilitation program, 92 experienced deterioration in function during this interval, defined as reduced reported exercise tolerance, new use of corticosteroids, or recent hospitalization, and they were evaluated with MUGA. We excluded 13 patients with overt cardiac disease who ...
Impact of surgical correction of pectus excavatum - diss.fu
Impact of surgical correction of pectus excavatum - diss.fu

... parameters as described in the literature and illustrated in Fig. 2. The Haller Index was calculated using the minimum sternovertebral distance (D) and the maximum transverse diameter of the chest wall (T) [13]. The chest wall asymmetry index was calculated as L/R ratio from assessed antero-posterio ...
This presentation will deal with the basics of ECG description as well
This presentation will deal with the basics of ECG description as well

... is slowed down, in order to let the ventricles fill with blood from atria contraction. This on ECG is represented by PQ segment (from the end of P wave to beginning of QRS complex). The electrical impulse is then quickly propagated through the His bundle to both bundle branches and ventricle myocard ...
The use of isovolumic contraction velocity to determine right
The use of isovolumic contraction velocity to determine right

... during the isovolumic contraction phase, measured by Doppler tissue imaging, has only recently in experimental models been shown to describe myocardial contractility. The aim of the present clinical study was to investigate the relationship between right ventricular isovolumic contraction velocity a ...
Effect of oral administration of pimobendan in cats with heart failure
Effect of oral administration of pimobendan in cats with heart failure

... ed median survival time of 13 days with conventional treatment.a The objective of the study reported here was to determine the effect of PO administration of pimobendan on clinical and echocardiographic variables and survival time in cats with HF characterized by ventricular systolic dysfunction. Ma ...
The structure and function of cardiac t
The structure and function of cardiac t

... of a number of key Ca2þ channels and contractile proteins. Indeed, a number of key proteins in this signalling pathway (e.g. stimulatory G-protein, Gs) are localized at the t-tubule [34]. Reports suggest that the b2-adrenoceptor (AR) system is more tightly coupled with the modulation of the LTCCs at ...
Arrhythmogenic right ventricular dysplasia and sudden death
Arrhythmogenic right ventricular dysplasia and sudden death

... ventricular dysplasia or cardiomiopathy appears to be related to the following two processes: (1) myocyte degeneration (including apoptosis and transdifferentiation), which may be inherited, and (2) interstitial inflammation, which may be infectious (probable postvital) or autoimmune in origin. Fatt ...
Prof. Saeed Abuel Makarem Dr. Jamila El Medany
Prof. Saeed Abuel Makarem Dr. Jamila El Medany

... interventricular  septum:   Division  of  the  primordial   ventricle  is  first  indicated   by  a  median  muscular   ridge,  the  primordial   interventricular  septum.   •  It  is  a  thick  crescen/c  fold   which  has  a  concave   ...
! General introduction Taco Kind
! General introduction Taco Kind

... The pulmonary artery originates at the RV and bifurcates into the left and right pulmonary artery, extending into the corresponding lung. Subsequent branching of the arteries continues progressively over the arterial tree. The proximal arteries are the most compliant vessels, which contain elastic l ...
Prevalence of electrocardiographic changes in patients with acute
Prevalence of electrocardiographic changes in patients with acute

... professionals must anticipate and recognize these changes. Evidence from a number of studies indicates that patients with SAH are at high risk for malignant ventricular arrhythmias if the QTc interval is prolonged. [4‑6] A decrease in cardiac output due to alterations in heart rate associated with S ...
Contemporary Reviews in Cardiovascular Medicine
Contemporary Reviews in Cardiovascular Medicine

... AF indicates atrial fibrillation; ALCAPA, anomalous left coronary artery from the pulmonary artery; AVB, AV block; AVN, AV node; BVH, biventricular hypertrophy; CHD, congenital heart disease; DILV, double-inlet left ventricle; EAR, ectoptic atrial rhythm; IART, intra-atrial reentrant tachycardia; LA ...
Underuse of Oral Anticoagulation for Individuals with Atrial
Underuse of Oral Anticoagulation for Individuals with Atrial

... he prevalence of atrial fibrillation (AF) is 5% in people aged 65 and older and approximately 10% in those aged 80 and older.1 The risk of mortality associated with AF events (hazard ratio = 2.14) includes death from cardiac and noncardiac causes.2 The most devastating consequence of AF is thromboem ...
Heart rate variability by Poincaré plot and spectral analysis in young
Heart rate variability by Poincaré plot and spectral analysis in young

... patients, compared to healthy people, have reduced HRV. This is a known phenomenon but the new message is that the reduced HRV in IDDM patients can also be found with the use of PP analysis. Moreover, it appears that PP analysis was more sensitive than spectral HRV to present attenuated autonomic mo ...
Pacemaker activity in an insect heart
Pacemaker activity in an insect heart

... chambers or valves. Closely associated with the heart are six pairs of alary muscles (Fig. 1A) and six pairs of ostia or openings. The alary muscles fan out from restricted origins on the abdominal segments, the muscle fibres of each side meeting in a broad zone at the heart. In this study, the alar ...
Emergency Diagnosis and Treatment of Acute Decompensated
Emergency Diagnosis and Treatment of Acute Decompensated

... ! ".0 CUTOFF VALUE OF  PGM, HAD ASENSITIVITYOFANDASPECIlCITYOF FORDIFFERENTIATINGHEARTFAILUREFROM OTHERCAUSESOFDYSPNEA ANDACUTOFFOF PGM,HADANEGATIVEPREDICTIVEVAL UE OF 7ITHOUT KNOWLEDGE OF ".0 LEVELS EMERGENCYPHYSICIANSHADA INDECI ...
Variations in Maximal Oxygen Intake with
Variations in Maximal Oxygen Intake with

... extraction (maximal arteriovenous oxygen difference). From table 3 it can be seen that both HR max and 02 pulse max parallel Vo2 max in showing a downward trend with advancing age. Whether the decrease of 02 pulse max with age represents diminished stroke volume, oxygen extraction, or both, cannot b ...
Current Status of Primary Prevention of Sudden Cardiac Death With
Current Status of Primary Prevention of Sudden Cardiac Death With

... Background:  The current status of primary prevention of sudden cardiac death (SCD) with implantable cardioverter defibrillator (ICD) in patients with heart failure with reduced ejection fraction remains to be fully elucidated in Japan. Methods and Results:  In the chronic heart failure (CHF) cohort ...
Final heart development
Final heart development

... By the end of the lecture you should be able to: • Describe the site, formation, union, and division of the of the heart tube. • Describe the formation and fate of the sinus venosus. • Describe the formation of the interatrial and the interventricular septae. • Describe the formation of the two atri ...
Spatiotemporal evolution of ventricular fibrillation
Spatiotemporal evolution of ventricular fibrillation

... initiated abruptly in both normal and compromised heart muscle and can, just as abruptly, be electrically terminated10. Ventricular fibrillation can exist as a stable state which is self-sustained and independent of its initiating event. The mechanisms underlying the pernicious stability of ventricu ...
Outcomes of patients with acute coronary syndromes and prior
Outcomes of patients with acute coronary syndromes and prior

... on death and MI were also collected at 180 days. A masked clinical events committee evaluated suspected infarcts. MI within 18 h after enrolment was diagnosed on the basis of ischaemic chest pain and new ST-segment elevation in at least two contiguous leads and lasting for 30 min. After 18 h, MI was ...
Non-coronary sinus of Valsalva aneurysm diagnosed after a road
Non-coronary sinus of Valsalva aneurysm diagnosed after a road

... and the ascending aorta and more extensive portions of the aortic root.2 In most cases, sinus of Valsalva aneurysms are diagnosed by transthoracic echocardiography because it enables the aortic root to be seen clearly. Doppler colour flow echocardiography is the best technique for the detection of c ...
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Myocardial infarction



Myocardial infarction (MI) or acute myocardial infarction (AMI), commonly known as a heart attack, occurs when blood flow stops to a part of the heart causing damage to the heart muscle. The most common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck, or jaw. Often it is in the center or left side of the chest and lasts for more than a few minutes. The discomfort may occasionally feel like heartburn. Other symptoms may include shortness of breath, nausea, feeling faint, a cold sweat, or feeling tired. About 30% of people have atypical symptoms, with women more likely than men to present atypically. Among those over 75 years old, about 5% have had an MI with little or no history of symptoms. An MI may cause heart failure, an irregular heartbeat, or cardiac arrest.Most MIs occur due to coronary artery disease. Risk factors include high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol intake, among others. The mechanism of an MI often involves the rupture of an atherosclerotic plaque, leading to complete blockage of a coronary artery. MIs are less commonly caused by coronary artery spasms, which may be due to cocaine, significant emotional stress, and extreme cold, among others. A number of tests are useful to help with diagnosis, including electrocardiograms (ECGs), blood tests, and coronary angiography. An ECG may confirm an ST elevation MI if ST elevation is present. Commonly used blood tests include troponin and less often creatine kinase MB.Aspirin is an appropriate immediate treatment for a suspected MI. Nitroglycerin or opioids may be used to help with chest pain; however, they do not improve overall outcomes. Supplemental oxygen should be used in those with low oxygen levels or shortness of breath. In ST elevation MIs treatments which attempt to restore blood flow to the heart are typically recommended and include angioplasty, where the arteries are pushed open, or thrombolysis, where the blockage is removed using medications. People who have a non-ST elevation myocardial infarction (NSTEMI) are often managed with the blood thinner heparin, with the additional use angioplasty in those at high risk. In people with blockages of multiple coronary arteries and diabetes, bypass surgery (CABG) may be recommended rather than angioplasty. After an MI, lifestyle modifications, along with long term treatment with aspirin, beta blockers, and statins, are typically recommended.Worldwide, more than 3 million people have ST elevation MIs and 4 million have NSTEMIs each year. STEMIs occur about twice as often in men as women. About one million people have an MI each year in the United States. In the developed world the risk of death in those who have had an STEMI is about 10%. Rates of MI for a given age have decreased globally between 1990 and 2010.
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