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Cutaneous Anthrax - UNC School of Medicine
Cutaneous Anthrax - UNC School of Medicine

... Endemic in SE Asia and northern Australia Common causative agent of community-acquired septicemia (Tran, Clinical & Experimental Dermatology, 2002) ...
Vaccinia (Smallpox) Vaccine
Vaccinia (Smallpox) Vaccine

... Variola virus is the etiological agent of smallpox. During the smallpox era, the only known reservoir for the virus was humans; no known animal or insect reservoirs or vectors existed. The most frequent mode of transmission was person-to-person, spread through direct deposit of infective droplets on ...
This article appeared in a journal published by Elsevier. The... copy is furnished to the author for internal non-commercial research
This article appeared in a journal published by Elsevier. The... copy is furnished to the author for internal non-commercial research

... for smallpox since its global eradication about 30 years ago. Thus, at least half of the population is now susceptible to the disease. Smallpox can be transmitted person-to-person and is highly lethal with a case-fatality rate of 20%, and on average the infected person shows no symptoms for the first ...
The cause of the plague of Athens
The cause of the plague of Athens

... of discussion among classical scholars and physicians for centuries, and the debate continues. Various infectious diseases have been proposed as the cause of the plague of Athens, and there is no consensus among classical scholars or physicians even regarding the most likely plausible explanation. T ...
Modeling Potential Responses to Smallpox as a Bioterrorist Weapon Research
Modeling Potential Responses to Smallpox as a Bioterrorist Weapon Research

... lated the smallest vaccine-induced reduction in transmission required to stop the outbreak within 365 days postrelease. This calculation was done by an iterative process in which the rate of transmission was reduced until the number of new cases per day reached approximately zero 365 days after rele ...
Smallpox vaccination and all-cause infectious disease
Smallpox vaccination and all-cause infectious disease

... of vaccination.4,5,7 For example, in a randomized controlled trial from Guinea-Bissau, children who had not received vitamin A at birth and were randomized to receive an additional measles vaccination at 4.5 months of age had a lower mortality rate than children randomized to no additional measles v ...
Eradication of Infectious Diseases: Its Concept, Then and Now
Eradication of Infectious Diseases: Its Concept, Then and Now

... SUMMARY: The concept of disease eradication emerged as recently as the mid-20th century. The successful eradication of smallpox resulted in the concept of the extinction of the causative agent in man as well as in the environment, leading to the cessation of all control measures including vaccinatio ...
Materials - Web Adventures
Materials - Web Adventures

... (electrons) to produce images of extremely small objects. With certain types of electron microscopes, objects as small as 0.2 nanometers can be seen. One nanometer is one billionth of a meter. ...
Modeling Responses to Anthrax and Smallpox Attacks
Modeling Responses to Anthrax and Smallpox Attacks

... has been a cause for concern, as is the possibility that stocks have been kept clandestinely in other parts of the world. In addition, because the virus’s genome has been published, some researchers are concerned that variola could be synthesized by using techniques of genetic engineering [7]. Small ...
Herd-immunity-for-IMCV - International Medical Council on
Herd-immunity-for-IMCV - International Medical Council on

... In India, doctors are concerned about profit margins being protected before human lives, with recommendations to vaccinate every child with more expensive, newer vaccines. Dr Jacob Puliyel describes the problems he sees. “An analysis in the Lancet showed how the Pneumococcal vaccine reduces only 4 c ...
Eichner, M. and K. Dietz. 2003. "Transmission potential
Eichner, M. and K. Dietz. 2003. "Transmission potential

... at places where people meet, such as in neighborhoods and at schools. The model only includes eight instances of places of this type; all high-school children attend the same school and the entire community is divided into four neighborhoods with 500 people each. Data from historical outbreaks suppo ...
Agent-Based Models As Policy Decision Tools: The Case of
Agent-Based Models As Policy Decision Tools: The Case of

... security concerns, this question has gained some urgency. The answer is not straightforward. The only known medication against smallpox is vaccination with cowpox virus. But a significant minority of individuals experience severe (and often fatal) adverse affects to the vaccine, such that a national ...
Infectious Agents as a Security Challenge: Experience of Typhus
Infectious Agents as a Security Challenge: Experience of Typhus

... time when the Spanish conquistadors conquered the New World, smallpox was used as a strong BW against the powerful empires of the Aztecs and Incas. When Hernan Cortes and his expedition landed on the coast of Mexico in 1519, aboard their boats were the goods infected with smallpox. The epidemic brok ...
Bioterrorism: A Medical Professional`s Perspective
Bioterrorism: A Medical Professional`s Perspective

anthrax as a biological weapon
anthrax as a biological weapon

... and microbiology of smallpox 2) To be able to recognize clinical smallpox 3) To be able control the secondary transmission of smallpox 4) To describe treatment and vaccination options for smallpox. ...
PowerPoint
PowerPoint

... – Monitor for 2 successive fevers > 101 º F (38.5C) – Travel restrictions during surveillance period for symptoms (incubation period) – No special ventilation requirements – All in home must be vaccinated – Household members with contraindications to vaccination should stay outside of home during su ...
Isolation and Quarantine Measures in Response
Isolation and Quarantine Measures in Response

... – Monitor for 2 successive fevers > 101 º F (38.5C) – Travel restrictions during surveillance period for symptoms (incubation period) – No special ventilation requirements – All in home must be vaccinated – Household members with contraindications to vaccination should stay outside of home during su ...
Vaccines - Quest Garden
Vaccines - Quest Garden

... and are therefore considered to be safe for use in immunocompromised patients. A third way of making a vaccine is to "attenuate" or weaken a live microorganism by aging it or altering its growth conditions. Vaccines made in this way are often the most successful vaccines, probably because they multi ...
FetschPresentationQ4..
FetschPresentationQ4..

... values and prove them accurate with past data ...
December 2008 - NWMOinfo.org
December 2008 - NWMOinfo.org

... “common good.” In 1905, for example, the U.S. Supreme Court ruled in Jacobson v. Massachusetts that the need to protect the public health through compulsory smallpox vaccination outweighed the individual’s right to privacy. Barring exceptions for religious belief, which exist in all but two U.S. sta ...
Dynamics and Control of Infectious Diseases
Dynamics and Control of Infectious Diseases

... Lethality: about 30% (depending on many factors, some types > 98%) Long incubation period: about 2-3 weeks (possibility of localized control measures) ...
Human-Human interaction: epidemiology
Human-Human interaction: epidemiology

... overall health status of a given population. In most countries of the world, publichealth authorities regularly gather epidemiological data on specific diseases and mortality rates in their populaces2. Main field of their studies focus on noninteracting systems. Most of knowledge came from analytic ...
Molluscum Contagiosum
Molluscum Contagiosum

... • Vaccinia has a broad host range that includes rabbits and mice. • At some time after Jenner’s original use of “cowpox” virus, the vaccine virus became “vaccinia virus”. • Vaccinia virus is unique in that it is an ‘artificial virus’ and does not occur in nature as such. • It may be the product of g ...
Biowarfare Agents that are WMD feasible
Biowarfare Agents that are WMD feasible

... these can be bought off the shelf for a few hundred dollars per copy which make PAPRs as a control as less reliable precursor. Technical hurdles towards the weaponization process include machining the agent into an aerosol. This process requires the scientist to have a refined machining capability t ...
Click the Icon to go to this months powerpoint presentation
Click the Icon to go to this months powerpoint presentation

... • Cholera; Darkfield and Phase contrast microscopes and culture. IV therapy for vomiting, losing greater than 7 liters a day, and shock. Killed vaccine that only protects for 6 months. Bactrim, Doxy, and TMP/SMX. • Pssitacosis(Parrot fever) 1-2 weeks incubation aerosolized dried droppings, aerosol a ...
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History of smallpox

The history of smallpox extends into pre-history; the disease likely emerged in human populations about 10,000 BC. The earliest credible evidence of smallpox is found in the Egyptian mummies of people who died some 3000 years ago. During the 18th century the disease killed an estimated 400,000 Europeans each year, including five reigning monarchs, and was responsible for a third of all blindness. Between 20 and 60% of all those infected—and over 80% of infected children—died from the disease.During the 20th century, it is estimated that smallpox was responsible for 300–500 million deaths. In the early 1950s an estimated 50 million cases of smallpox occurred in the world each year. As recently as 1967, the World Health Organization estimated that 15 million people contracted the disease and that two million died in that year. After successful vaccination campaigns throughout the 19th and 20th centuries, the WHO certified the eradication of smallpox in December 1979. To this day, smallpox is the only human infectious disease to have been completely eradicated.
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