Lowgrade systolic murmurs in healthy middleaged individuals
... second half of the follow-up. Three men had AVR during the first 5 years of follow-up: one man in the lowgrade murmur group at 4.6 years and two men in the moderate-grade murmur group, both with grade IV murmurs, at 3.7 and 4.1 years, respectively. The median interval from baseline to AVR was 14.3 y ...
... second half of the follow-up. Three men had AVR during the first 5 years of follow-up: one man in the lowgrade murmur group at 4.6 years and two men in the moderate-grade murmur group, both with grade IV murmurs, at 3.7 and 4.1 years, respectively. The median interval from baseline to AVR was 14.3 y ...
Arterial Stiffness in the Young: Assessment
... The ‘fetal origins hypothesis’57) proposes that cardiovascular disease originates through adaptation to an adverse environment in utero. These adaptations have been suggested to cause permanent alterations in cardiovascular structure and physiology through the process of programming. Indeed, there i ...
... The ‘fetal origins hypothesis’57) proposes that cardiovascular disease originates through adaptation to an adverse environment in utero. These adaptations have been suggested to cause permanent alterations in cardiovascular structure and physiology through the process of programming. Indeed, there i ...
Neuroleptic Malignant Syndrome: A Review
... Objective: Neuroleptic malignant syndrome is an uncommon side effect of antipsychotic medications characterized by severe rigidity, tremor, fever, altered mental status, autonomic dysfunction, and elevated serum creatinine phosphokinase and white blood cell count. This paper presents a concise and c ...
... Objective: Neuroleptic malignant syndrome is an uncommon side effect of antipsychotic medications characterized by severe rigidity, tremor, fever, altered mental status, autonomic dysfunction, and elevated serum creatinine phosphokinase and white blood cell count. This paper presents a concise and c ...
Superior Vena Cava Syndrome
... inspection. The variety of collateral circulation and the differences in the venous rearrangement are expression of the SVC obstruction site (Figure 3,4,5). The anatomic classification includes three levels of obstruction: 1. Obstruction of the upper SVC, proximal to the azygos entry point. 2. Obstr ...
... inspection. The variety of collateral circulation and the differences in the venous rearrangement are expression of the SVC obstruction site (Figure 3,4,5). The anatomic classification includes three levels of obstruction: 1. Obstruction of the upper SVC, proximal to the azygos entry point. 2. Obstr ...
Click here for handout
... heart disease “Congenital affections of the heart have only a limited clinical interest, as in a large proportion of the cases the anomaly is not compatible with life, and in others nothing can be done to remedy the defect or even relieve symptoms.” Sir William Osler 1892 ...
... heart disease “Congenital affections of the heart have only a limited clinical interest, as in a large proportion of the cases the anomaly is not compatible with life, and in others nothing can be done to remedy the defect or even relieve symptoms.” Sir William Osler 1892 ...
Brugada Syndrome (2015)
... Inheritance can be autosomal dominant with incomplete penetrance, or be polygenic.(2, 3) It can also appear as a consequence of structural changes in the right ventricular outflow tract from a variety of causes. BrS is reported to be responsible for 4% of all sudden deaths and 20% o ...
... Inheritance can be autosomal dominant with incomplete penetrance, or be polygenic.(2, 3) It can also appear as a consequence of structural changes in the right ventricular outflow tract from a variety of causes. BrS is reported to be responsible for 4% of all sudden deaths and 20% o ...
Aortic Valve and Ascending Aorta Guidelines for Management and
... The guidelines address only the adult population and not the pediatric population. When needed, they draw heavily from the previously published 2010 ACC/AHA document, and thus, indications for surgery are not covered in detail except where new evidence suggests an update is needed. The previous guid ...
... The guidelines address only the adult population and not the pediatric population. When needed, they draw heavily from the previously published 2010 ACC/AHA document, and thus, indications for surgery are not covered in detail except where new evidence suggests an update is needed. The previous guid ...
Invasive Hemodynamic Characteristics of Low Gradient
... (mean systolic gradient ⬍40 mm Hg). The latest European guidelines therefore acknowledge that “the possible presence of severe aortic stenosis in patients with valve area ⬍1.0 cm2 and mean gradient ⬍40 mm Hg, despite preserved LVEF, has been suggested” (1). Low gradient severe aortic stenosis despit ...
... (mean systolic gradient ⬍40 mm Hg). The latest European guidelines therefore acknowledge that “the possible presence of severe aortic stenosis in patients with valve area ⬍1.0 cm2 and mean gradient ⬍40 mm Hg, despite preserved LVEF, has been suggested” (1). Low gradient severe aortic stenosis despit ...
Aortic Stenosis: Pathophysiology, Diagnosis, and Medical Management of
... vessels appear.13 In aortic stenosis, calcium nodules located within the layers of the leaflet bulge outward toward the aorta and extend to the sinuses of Valsalva, causing restricted leaflet motion and obstruction of left ventricular outflow during systole1,13 (Figure 7). The 1% to 2% of adults bo ...
... vessels appear.13 In aortic stenosis, calcium nodules located within the layers of the leaflet bulge outward toward the aorta and extend to the sinuses of Valsalva, causing restricted leaflet motion and obstruction of left ventricular outflow during systole1,13 (Figure 7). The 1% to 2% of adults bo ...
Contemporary Reviews in Cardiovascular
... the thoracic aorta that often occurs with later age (see discussion). In fact, on the basis of the chest x-ray film alone, one cannot typically distinguish whether an enlarged aortic silhouette represents a tortuous aorta or the presence of an aneurysm. Consequently, if a chest x-ray film shows an e ...
... the thoracic aorta that often occurs with later age (see discussion). In fact, on the basis of the chest x-ray film alone, one cannot typically distinguish whether an enlarged aortic silhouette represents a tortuous aorta or the presence of an aneurysm. Consequently, if a chest x-ray film shows an e ...
An Improved Method for Echographic Detection of Left
... Ani echographic "sweep' of the left ventricular outflow tract utilizing a continuous strip) chart recorder (record not retoulched). Area A is the central region of the left ventricle (LV) and is characterized by the echoes from the interve ntricuilar septum (IVS), left ventricular posterior wall (LV ...
... Ani echographic "sweep' of the left ventricular outflow tract utilizing a continuous strip) chart recorder (record not retoulched). Area A is the central region of the left ventricle (LV) and is characterized by the echoes from the interve ntricuilar septum (IVS), left ventricular posterior wall (LV ...
Transcatheter Aortic Valve Implantation for Aortic Stenosis
... randomized trials have compared the self-expandable valve with best medical therapy. However, results from the single-arm CoreValve Extreme Risk Pivotal Trial met the authors’ prespecified objective performance goal. The evidence is sufficient to determine qualitatively that the technology results i ...
... randomized trials have compared the self-expandable valve with best medical therapy. However, results from the single-arm CoreValve Extreme Risk Pivotal Trial met the authors’ prespecified objective performance goal. The evidence is sufficient to determine qualitatively that the technology results i ...
СARRENT ISSUES OF THE AORTIC FUNCTIONAL MORPHOLOGY
... small aortic branches within 1 mm of their origin. The interest of pathologists in reflexogenic areas of the heart and aorta in the 50–60s of the XX century is clear as it was the period of experimental and later clinical heart transplant. N. M. Bykov (1951) described the nodule 1–2 mm in diameter l ...
... small aortic branches within 1 mm of their origin. The interest of pathologists in reflexogenic areas of the heart and aorta in the 50–60s of the XX century is clear as it was the period of experimental and later clinical heart transplant. N. M. Bykov (1951) described the nodule 1–2 mm in diameter l ...
I I I - docvadis
... If the maximal cross-sectional area in square centimeters of the ascending aorta or root divided by the patient's height in meters exceeds a ratio of 10, surgical repair is reasonable because shorter patients have dissection at a smaller size and 15% of patients with Marfan syndrome have dissection ...
... If the maximal cross-sectional area in square centimeters of the ascending aorta or root divided by the patient's height in meters exceeds a ratio of 10, surgical repair is reasonable because shorter patients have dissection at a smaller size and 15% of patients with Marfan syndrome have dissection ...
Overview - Professional Heart Daily
... If the maximal cross-sectional area in square centimeters of the ascending aorta or root divided by the patient's height in meters exceeds a ratio of 10, surgical repair is reasonable because shorter patients have dissection at a smaller size and 15% of patients with Marfan syndrome have dissection ...
... If the maximal cross-sectional area in square centimeters of the ascending aorta or root divided by the patient's height in meters exceeds a ratio of 10, surgical repair is reasonable because shorter patients have dissection at a smaller size and 15% of patients with Marfan syndrome have dissection ...
Overview - Cardio.nl
... If the maximal cross-sectional area in square centimeters of the ascending aorta or root divided by the patient's height in meters exceeds a ratio of 10, surgical repair is reasonable because shorter patients have dissection at a smaller size and 15% of patients with Marfan syndrome have dissection ...
... If the maximal cross-sectional area in square centimeters of the ascending aorta or root divided by the patient's height in meters exceeds a ratio of 10, surgical repair is reasonable because shorter patients have dissection at a smaller size and 15% of patients with Marfan syndrome have dissection ...
Carrent issues of the aortic functional morphology
... The opinion on the depth of location of sensitive nerve endings in the aortic wall differ [2,3,9,12,16,20,29]. So, A. Abraham (1950, 1953, 1961, 1963) notes the absence of baroreceptors in the aotric media. In the same years A.V.Babaskin (1952, 1953) and later B.M.Smolkina (1967) describe the single ...
... The opinion on the depth of location of sensitive nerve endings in the aortic wall differ [2,3,9,12,16,20,29]. So, A. Abraham (1950, 1953, 1961, 1963) notes the absence of baroreceptors in the aotric media. In the same years A.V.Babaskin (1952, 1953) and later B.M.Smolkina (1967) describe the single ...
Case Report Compression of the ostium of left main coronary artery
... For this case, the patient’ left main coronary artery was severely occlusive because of aortic root intramural hematoma. The clinical presentation of IMH is indistinguishable from that of acute aortic dissection, which has no aortic intimal tear and communication with the true lumen. For trauma pati ...
... For this case, the patient’ left main coronary artery was severely occlusive because of aortic root intramural hematoma. The clinical presentation of IMH is indistinguishable from that of acute aortic dissection, which has no aortic intimal tear and communication with the true lumen. For trauma pati ...
Brugada Syndrome - Circulation: Arrhythmia and Electrophysiology
... SCD compared with women, but arrhythmic events may occur from age 2 days to 84 years.49 BrS is also known as one of the causes for sudden infant death syndrome or SCD in young children.15,50 The prevalence of BrS appears to be low in the general population. According to recent studies in Europe, the ...
... SCD compared with women, but arrhythmic events may occur from age 2 days to 84 years.49 BrS is also known as one of the causes for sudden infant death syndrome or SCD in young children.15,50 The prevalence of BrS appears to be low in the general population. According to recent studies in Europe, the ...
Multimodality Imaging Strategies for the Assessment of Aortic Stenosis
... LV cavity (end-diastolic volume index, <55 mL/m2), restrictive LV diastolic pattern, and reduced global longitudinal strain (global strain, <16%).3,8,10 However, the LF state may also occur because of concomitant mitral regurgitation, tricuspid regurgitation, atrial fibrillation, constrictive perica ...
... LV cavity (end-diastolic volume index, <55 mL/m2), restrictive LV diastolic pattern, and reduced global longitudinal strain (global strain, <16%).3,8,10 However, the LF state may also occur because of concomitant mitral regurgitation, tricuspid regurgitation, atrial fibrillation, constrictive perica ...
the carotid pulse i: diagnosis of aortic stenosis by external
... not seen, particularly in the more severe cases. To achieve a high level of accuracy in diagnosis, it has proved necessary to consider three aspects of the pulse-the contour, the upstroke time, and the ejection time. Analysed in this way, aortic stenosis could be recognized in 32 out of 33 patients, ...
... not seen, particularly in the more severe cases. To achieve a high level of accuracy in diagnosis, it has proved necessary to consider three aspects of the pulse-the contour, the upstroke time, and the ejection time. Analysed in this way, aortic stenosis could be recognized in 32 out of 33 patients, ...
Aortic stenosis: Who should undergo surgery, transcatheter valve
... the Western world, affects mainly people over age 60. It is characterized by years to decades of slow progression followed by rapid clinical deterioration and a high death rate once symptoms develop. Drug therapy for it remains ineffective, and surgical aortic valve replacement is the only effective ...
... the Western world, affects mainly people over age 60. It is characterized by years to decades of slow progression followed by rapid clinical deterioration and a high death rate once symptoms develop. Drug therapy for it remains ineffective, and surgical aortic valve replacement is the only effective ...
Mechanisms And Prevention Of TAVI
... undergoing TAVI have multiple cardiovascular risk factors including hypertension, hyperlipidemia, a history of smoking, and diabetes mellitus, which often lead to atherosclerotic disease in this aged patient population. Thus, it is conceivable that each and every manipulation during the TAVI procedu ...
... undergoing TAVI have multiple cardiovascular risk factors including hypertension, hyperlipidemia, a history of smoking, and diabetes mellitus, which often lead to atherosclerotic disease in this aged patient population. Thus, it is conceivable that each and every manipulation during the TAVI procedu ...
Heart Sounds
... time, his parents were told he would “outgrow” the murmur. The patient participates actively in sports without any cardiac symptoms. On physical exam, S1 is normal, S2 is physiologically split. A thrill is noted in the third left intercostal space and a 4/6 holosytolic murmur is noted along the left ...
... time, his parents were told he would “outgrow” the murmur. The patient participates actively in sports without any cardiac symptoms. On physical exam, S1 is normal, S2 is physiologically split. A thrill is noted in the third left intercostal space and a 4/6 holosytolic murmur is noted along the left ...
Cardiovascular magnetic resonance assessment of the aortic valve
... performed via the percutaneous femoral approach, including right and left heart pressure measurement. Peak to peak and mean pressure gradients were determined between left ventricle and ascending aorta. Cardiac output was measured by thermodilution, averaging at least 3 measurements. AVA was estimat ...
... performed via the percutaneous femoral approach, including right and left heart pressure measurement. Peak to peak and mean pressure gradients were determined between left ventricle and ascending aorta. Cardiac output was measured by thermodilution, averaging at least 3 measurements. AVA was estimat ...
Turner syndrome
Turner syndrome (TS) also known as Ullrich–Turner syndrome, gonadal dysgenesis, and 45,X, is a condition in which a female is partly or completely missing an X chromosome. Signs and symptoms vary among those affected. Often, a short and webbed neck, low-set ears, low hairline at the back of the neck, short stature, and swollen hands and feet are seen at birth. Typically they are without menstrual periods, do not develop breasts, and are unable to have children. Heart defects, diabetes, and low thyroid hormone occur more frequently. Most people with TS have normal intelligence. Many, however, have troubles with spatial visualization such as that needed for mathematics. Vision and hearing problems occur more often.Turner syndrome is not usually inherited from a person's parents. No environmental risks are known and the mother's age does not play a role. Turner syndrome is due to a chromosomal abnormality in which all or part of one of the X chromosomes is missing or altered. While most people have 46 chromosomes, people with TS usually only have 45. The chromosomal abnormality may be present in just some cells in which case it is known as TS with mosaicism. In these cases, the symptoms are usually fewer and possibly none occur at all. Diagnosis is based on physical signs and genetic testing.No cure for Turner syndrome is known. Treatment, however, may help with symptoms. Human growth hormone injections during childhood may increase adult height. Estrogen replacement therapy can promote development of the breasts and hips. Medical care is often required to manage other health problems with which TS is associated.Turner syndrome occurs in between one in 2000 and one in 5000 females at birth. All regions of the world and cultures are affected about equally. People with TS have a shorter life expectancy, mostly due to heart problems and diabetes. Henry Turner first described the condition in 1938. In 1964, it was determined to be due to a chromosomal abnormality.