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Hijacked: The role of platelets in dengue virus infection revealed
Hijacked: The role of platelets in dengue virus infection revealed

... cells and use the cell’s internal machinery to replicate their own genetic material (in the case of dengue, singlestranded RNA). New viruses are then released from the infected cell, continuing the cycle of infectivity. Dengue virus infections have a three to 14-day window period before symptoms app ...
Bacteriology - UAB School of Optometry
Bacteriology - UAB School of Optometry

No Slide Title
No Slide Title

... • Immune reactivity after OLTx is a self organizing/selfregulating system, but hard to define nodal points on basis of histopathology, alone. • Acute rejection not a major problem in liver transplantation – Mild acute rejection may not require treatment. – More severe acute rejection can lead to pro ...
SARS virus
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... Upon infection of a host cell, the 5’ most open reading frame (ORF) of the viral genome is translated into a large polyprotein that is cleaved by viral-encoded proteases to release several nonstructural proteins including an RNAdependent RNA polymerase (Rep) and ATPase helicase (Hel). These proteins ...
Bacteremia and Sepsis - University of Yeditepe Faculty of
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... • Frequently reflects the presence of serious infections • Life-threatening in immunocompromised • Often associated with hospitalization and instrumentation ...
Healthcare Personnel Vaccination Recommendations
Healthcare Personnel Vaccination Recommendations

... the vaccinee is immune. No further serologic testing or vaccination is recommended. • If anti-HBs is less than 10 mIU/mL (negative), the vaccinee is not protected from hepatitis B virus (HBV) infection, and should receive 3 additional doses of HepB vaccine on the routine schedule, followed by anti- ...
Fever in ICU
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... C.difficile–associated diarrhea  Cultures for C. difficile require 2 to 3 days for growth, and are not specific in distinguishing toxin-positive strains, toxinnegative strains, and asymptomatic carriage.  Infection with Klebsiella oxytoca should be considered in patients who are negative for C. d ...
The Flavivirus Envelope Protein E: Isolation of a Soluble Form from
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... to the removal of approximately 80 amino acids at the carboxy terminus. In contrast, the removal of the membrane anchor does not seem to be responsible for the loss of reactivity with the isolated epitope i2, since a similar result was also obtained with solubilized and aggregated (rosettelike) form ...
Guidelines for Research Involving Viral Vectors
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to view a sample chapter of SACE1 Biology
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... My work aims to understand how a group of the most devastating fungal pathogens of wheat invades their host plant. The pathogens are called Fusarium graminearum and its close relative, Fusarium pseudograminearum. During infection they produce a toxin, called deoxynivalenol, which both assists with i ...
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... of the liver, which along with other clinical information, can be used to gauge the level of fibrosis present in the liver. TE at 50Hz uses ultrasound to make measurements of the stiffness of the liver. The velocity of a vibration wave (or shear wave) is measured by the time it takes to travel to a ...
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... quantitate. Important in any risk assessment is the level of concentration of contaminant which is required to cause a health effect. Ideally, maximum contaminant levels for potentially harmful substances would be established on firm epidemiological evidence, where cause and effect can be clearly qu ...
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...  What is epidemiology?  What do the following terms mean: o Determinants (recognize examples) o Distribution  What is the difference between morbidity and mortality?  What are the four aims and levels in epidemiology? Be able to explain each.  What are the two main goals of epidemiology?  Epid ...
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itching and scratching guided notes [2/17/2017]
itching and scratching guided notes [2/17/2017]

... with an STI, because teens are usually less responsible with regard to using protection and believe they won’t get infected. The cervix of a teenage girl is more susceptible to contracting STIs than that of an adult woman. Lots of partners: People who have sexual contact - not just intercourse, but ...
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... inflamed, the nose tends to become blocked because the sinuses cannot drain mucus properly. Breathing becomes difficult, and sinus pressure and pain typically follow. Pets suffering from sinus congestion and inflammation may also exhibit reduced appetite, runny nose and sneezing as well. The underly ...
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... According to the California Department of Public Health, the number of measles cases continues to rise in California. As you may know, Measles is a highly infectious, airborne disease that typically begins with fever, cough, runny nose, and red eyes and within a few days a red rash appears, usually ...
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Hepatitis B



Hepatitis B is an infectious disease caused by the hepatitis B virus (HBV) which affects the liver. It can cause both acute and chronic infections. Many people have no symptoms during the initial infection. Some develop a rapid onset of sickness with vomiting, yellowish skin, feeling tired, dark urine and abdominal pain. Often these symptoms last a few weeks and rarely does the initial infection result in death. It may take 30 to 180 days for symptoms to begin. In those who get infected around the time of birth 90% develop chronic hepatitis B while less than 10% of those infected after the age of five do. Most of those with chronic disease have no symptoms; however, cirrhosis and liver cancer may eventually develop. These complications results in the death of 15 to 25% of those with chronic disease.The virus is transmitted by exposure to infectious blood or body fluids. Infection around the time of birth or from contact with other people's blood during childhood is the most frequent method by which hepatitis B is acquired in areas where the disease is common. In areas where the disease is rare, intravenous drug use and sexual intercourse are the most frequent routes of infection. Other risk factors include working in healthcare, blood transfusions, dialysis, living with an infected person, travel in countries where the infection rate is high, and living in an institution. Tattooing and acupuncture led to a significant number of cases in the 1980s; however, this has become less common with improved sterility. The hepatitis B viruses cannot be spread by holding hands, sharing eating utensils, kissing, hugging, coughing, sneezing, or breastfeeding. The infection can be diagnosed 30 to 60 days after exposure. Diagnosis is typically by testing the blood for parts of the virus and for antibodies against the virus. It is one of five known hepatitis viruses: A, B, C, D, and E.The infection has been preventable by vaccination since 1982. Vaccination is recommended by the World Health Organization in the first day of life if possible. Two or three more doses are required at a later time for full effect. This vaccine works about 95% of the time. About 180 countries gave the vaccine as part of national programs as of 2006. It is also recommended that all blood be tested for hepatitis B before transfusion and condoms be used to prevent infection. During an initial infection, care is based on the symptoms that a person has. In those who develop chronic disease antiviral medication such as tenofovir or interferon maybe useful, however these drugs are expensive. Liver transplantation is sometimes used for cirrhosis.About a third of the world population has been infected at one point in their lives, including 240 million to 350 million who have chronic infections. Over 750,000 people die of hepatitis B each year. About 300,000 of these are due to liver cancer. The disease is now only common in East Asia and sub-Saharan Africa where between 5 and 10% of adults have chronic disease. Rates in Europe and North America are less than 1%. It was originally known as serum hepatitis. Research is looking to create foods that contain HBV vaccine. The disease may affect other great apes as well.
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