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Reproduction numbers for infections with free
Reproduction numbers for infections with free

... transmit infection to susceptible hosts [6,12,44]. Pathogens in a free-living state adapt to the environment by morphological and physiological changes that promote their survival [5] and even growth [36] in the environment. In addition, the presence of a free-living pathogen (FLP) in the environmen ...
Radioimmunotherapy of Infectious Diseases Ekaterina Dadachova, PhD* and Arturo Casadevall, MD, PhD
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... survival. Interestingly, the 200-␮Ci (7.4 MBq) dose of 213Bi18B7 was less efficient, possibly because it may have approached the maximum tolerated activity for this particular combination of antibody and radioisotope. In the 188Re group, administration of 50 ␮Ci (1.85 MBq) of 188Re-18B7 resulted in ...
Choose Bloodborne Pathogen and Biomedical Waste Training
Choose Bloodborne Pathogen and Biomedical Waste Training

... Many infectious agents yet to be discovered and for which there is no test ...
Pre-meeting document. - Viral Hepatitis Prevention Board
Pre-meeting document. - Viral Hepatitis Prevention Board

... benefit from immunisation, there is now considerable agreement from both epidemiological and practical viewpoints that such high-risk group strategies will not lead to a significant reduction of HBV infection on a national or international scale. High-risk groups are difficult to reach with currentl ...
BIOHAZARD CONTROL PROGRAM, BLOOD
BIOHAZARD CONTROL PROGRAM, BLOOD

... needles and other sharp items that may have been exposed to PIM’s. Standard Precautions refers to a system of precautions designed to protect persons from harmful exposure to Potentially Infectious Materials. It is an expansion of universal precautions and body substance isolation procedures and ass ...
Picornaviruses
Picornaviruses

... for cellular receptors is the major determinant of the target tissue tropism and disease VP1 and “canyon” 80% of rhinoviruses and several serotypes of of coxsackieviruses recognize ICAM-1 ...
Immunoproteomics: the Key to Discovery of New Vaccine Antigens
Immunoproteomics: the Key to Discovery of New Vaccine Antigens

... Abstract: The increase in antibiotic resistance and the shortage of new antimicrobials to prevent difficult bacterial infections underlines the importance of prophylactic therapies to prevent infection by bacterial pathogens. Vaccination has reduced the incidence of many serious diseases, including ...
Foot-and-mouth disease: an assessment of the risks facing New
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... The most convincing support for long distance airborne spread arose through the use of such models immediately prior to the outbreak on the Isle of Wight in 1981, when it was predicted that spread from infected piggeries in Brittany was likely – a distance of 250 km (Donaldson et al 1982). This notw ...
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Bloodborne Pathogen Training - Research

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EXERCISE 1: INFECTION CONTROL Skills: 10 points Objectives: 1
EXERCISE 1: INFECTION CONTROL Skills: 10 points Objectives: 1

... transmissible or epidemiologically important pathogens for which additional precautions beyond Standard Precautions are needed to interrupt transmission in hospitals. There are three types of Transmission-Based Precautions: Airborne Precautions, Droplet Precautions, and Contact Precautions. They may ...
Infection Control - Austin Community College
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... transmissible or epidemiologically important pathogens for which additional precautions beyond Standard Precautions are needed to interrupt transmission in hospitals. There are three types of Transmission-Based Precautions: Airborne Precautions, Droplet Precautions, and Contact Precautions. They may ...
HIV Superinfection - Division of Infectious Diseases
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... limited window of susceptibility to superinfection. Compared with chronically infected individuals, individuals with early HIV infection—and, thus, an immature HIV-specific immune response—may be the most likely to acquire the second strain of virus. However, the type of exposure and the intrahost v ...
Escherichia coli O157 - International Scientific Forum on Home
Escherichia coli O157 - International Scientific Forum on Home

... (haemorrhagic colitis). Haemorrhagic colitis is often accompanied by severe abdominal cramps but usually without fever. The incubation period for infection before the onset of diarrhoea can range from 1 to 14 days. Symptoms usually resolve within two weeks. Where is E. coli O157 found? Over 15% of h ...
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What’s up with the flu? - Winona Senior High School

keynote_1997 - International Scientific Forum on Home Hygiene
keynote_1997 - International Scientific Forum on Home Hygiene

... day cleaning of the home. In practice, home hygiene encompasses something much wider. Micro-organisms are introduced continually into the home in a number of ways - on people, food, pets, insects and via water. In addition certain areas or sites in the home environment where stagnant water and organ ...
Risk assessment on xenotropic murine leukemia virus
Risk assessment on xenotropic murine leukemia virus

... (i.e. MeSH and Emtree terms). The concepts were completed with multiple field search combinations by using natural vocabulary (i.e. keywords) according to the adequacy and number of results retrieved in each of the search strategies. The results were taken from all languages and limited to 2006 and ...
syphilis: clinical Manifestations, Diagnosis, and Management
syphilis: clinical Manifestations, Diagnosis, and Management

... and transmitting HIV.3,4 According to the Centers for Disease Control and Prevention (CDC), the median proportion of MSM with primary and secondary syphilis who were also infected with HIV in ...
1 Section VIII - Bloodborne Pathogens Exposure Control Plan
1 Section VIII - Bloodborne Pathogens Exposure Control Plan

... The name and social security number of the employee. A copy of the Hepatitis B vaccination record or signed declination form. The circumstances of the exposure incident including a description of the exposed employee’s duties as they relate to the exposure incident and results of the source individu ...
Directed Reading 10.3b Viruses
Directed Reading 10.3b Viruses

... 20. In the lytic cycle, a virus joins a cell and injects it with the virus’s ______________________material. 21. During the lytic cycle, a virus’s genes take over the host and make______________________. 22. Newly made viruses break out of the______________________, which then dies. A Time Bomb ...
on Immune Function
on Immune Function

... decline in immunity that can lead to the acquired immunodeficiency syndrome (AIDS). HIV-1 is spread person-to-person by three major routes: sexual contact, motherto-child transmission, and through transmission by blood products such as shared needles and syringes. ...
Infectious Bursal Disease: Pathogenicity and
Infectious Bursal Disease: Pathogenicity and

... lymphocyte depletion in bursal follicles (Muller et al., 1979). The infection with IBDV may exacerbate previous infections with other infectious agents, and may reduce the capacity of the bird to respond to vaccination, as the virus damages the humoral and cellular immune responses of chickens (Shar ...
Recommendations for breastfeeding during maternal infections
Recommendations for breastfeeding during maternal infections

... In case of HBsAg-seropositive mothers during pregnancy, the infant should receive the first dose of the vaccine immediately after delivery and hepatitis B hyperimmune immunoglobulin (0.5 ml IM) in the first 12 hours of life, given concomitantly, but in different sites. This practice has an efficienc ...
History of HPV Detection - EvergreenStateCollege-Home
History of HPV Detection - EvergreenStateCollege-Home

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Hepatitis B



Hepatitis B is an infectious disease caused by the hepatitis B virus (HBV) which affects the liver. It can cause both acute and chronic infections. Many people have no symptoms during the initial infection. Some develop a rapid onset of sickness with vomiting, yellowish skin, feeling tired, dark urine and abdominal pain. Often these symptoms last a few weeks and rarely does the initial infection result in death. It may take 30 to 180 days for symptoms to begin. In those who get infected around the time of birth 90% develop chronic hepatitis B while less than 10% of those infected after the age of five do. Most of those with chronic disease have no symptoms; however, cirrhosis and liver cancer may eventually develop. These complications results in the death of 15 to 25% of those with chronic disease.The virus is transmitted by exposure to infectious blood or body fluids. Infection around the time of birth or from contact with other people's blood during childhood is the most frequent method by which hepatitis B is acquired in areas where the disease is common. In areas where the disease is rare, intravenous drug use and sexual intercourse are the most frequent routes of infection. Other risk factors include working in healthcare, blood transfusions, dialysis, living with an infected person, travel in countries where the infection rate is high, and living in an institution. Tattooing and acupuncture led to a significant number of cases in the 1980s; however, this has become less common with improved sterility. The hepatitis B viruses cannot be spread by holding hands, sharing eating utensils, kissing, hugging, coughing, sneezing, or breastfeeding. The infection can be diagnosed 30 to 60 days after exposure. Diagnosis is typically by testing the blood for parts of the virus and for antibodies against the virus. It is one of five known hepatitis viruses: A, B, C, D, and E.The infection has been preventable by vaccination since 1982. Vaccination is recommended by the World Health Organization in the first day of life if possible. Two or three more doses are required at a later time for full effect. This vaccine works about 95% of the time. About 180 countries gave the vaccine as part of national programs as of 2006. It is also recommended that all blood be tested for hepatitis B before transfusion and condoms be used to prevent infection. During an initial infection, care is based on the symptoms that a person has. In those who develop chronic disease antiviral medication such as tenofovir or interferon maybe useful, however these drugs are expensive. Liver transplantation is sometimes used for cirrhosis.About a third of the world population has been infected at one point in their lives, including 240 million to 350 million who have chronic infections. Over 750,000 people die of hepatitis B each year. About 300,000 of these are due to liver cancer. The disease is now only common in East Asia and sub-Saharan Africa where between 5 and 10% of adults have chronic disease. Rates in Europe and North America are less than 1%. It was originally known as serum hepatitis. Research is looking to create foods that contain HBV vaccine. The disease may affect other great apes as well.
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