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Urbanization and the Epidemiology of Infectious Diseases
Urbanization and the Epidemiology of Infectious Diseases

... -  Disease of infancy -  Asymptomatic or subclinical infection -  Partial protection by maternal antibodies -  All children immune by 4 years of age ...
Vaccine Development Using Recombinant DNA Technology
Vaccine Development Using Recombinant DNA Technology

... animal (Rodriguez and Whitton 2000). Plasmids can be maintained in bacteria (usually E. coli) and have been designed to accept foreign genes for expression in animals. The recombinant plasmids containing a foreign gene are purified from the bacteria, and the “naked” DNA is injected directly into the ...
Avian influenza virus, Streptococcus suis serotype 2, severe acute
Avian influenza virus, Streptococcus suis serotype 2, severe acute

... GenBank (A/Hong Kong/W213/1997). Two human cases were associated with this outbreak and both the 13-month-old and the 4-year-old girls who were infected had uncomplicated influenza-like illness and fully recovered after medical treatment. Further studies on those who had contact with those young pat ...
Dr. Mohamed Awad Tag El Din presentation about "Respiratory
Dr. Mohamed Awad Tag El Din presentation about "Respiratory

...  CAP often causes problems like breathing, fever, chest pains, and cough.  CAP occurs because the areas of the lung which absorb oxygen (alveoli) from the atmosphere become filled with fluid and cannot work effectively. ...
4. Air shipment - summary of current regulations
4. Air shipment - summary of current regulations

... Serum, rather than whole blood, must be submitted for antibody testing. A minimum of 4 ml is essential. Should lesser amounts be submitted there is a risk that re-sampling may be required with subsequent delay. It is essential that sterile containers be used. If sera have been collected under steril ...
Fulminant hepatic failure in children
Fulminant hepatic failure in children

... and in patients with primary or secondary immunodeficiency [20]; however, there have also been rare reports of apparently immunocompetent children whose deaths were attributed to fatal HSV hepatitis [21]. Rare fatal causes of Epstein–Barr virus (EBV)-associated fulminant hepatitis have been reported ...
Vaccine Development Using Recombinant DNA Technology
Vaccine Development Using Recombinant DNA Technology

... animal (Rodriguez and Whitton 2000). Plasmids can be maintained in bacteria (usually E. coli) and have been designed to accept foreign genes for expression in animals. The recombinant plasmids containing a foreign gene are purified from the bacteria, and the “naked” DNA is injected directly into the ...
Vaccine Development Using Recombinant DNA Technology
Vaccine Development Using Recombinant DNA Technology

... animal (Rodriguez and Whitton 2000). Plasmids can be maintained in bacteria (usually E. coli) and have been designed to accept foreign genes for expression in animals. The recombinant plasmids containing a foreign gene are purified from the bacteria, and the “naked” DNA is injected directly into the ...
biosafety guide
biosafety guide

... Walls, floors, ceilings impervious to water so they can be easily cleaned. Biosafety Cabinets (Class II) must be installed and certified annually. Re-certification is necessary when a biosafety cabinet is moved. Biosafety Cabinet exhaust must be filtered through a HEPA filter before being discharged ...
Virulence Comparison of Three Buhl-Subtype Isolates of Infectious
Virulence Comparison of Three Buhl-Subtype Isolates of Infectious

... cause high mortality in populations of young salmonids. To determine the molecular basis of virulence, the fry of brook trout Salvelinus fontinalis were experimentally infected with three different A1-serotype, Buhl-subtype isolates of IPNV. The three isolates were selected on the basis of results o ...
Mount Sinai School of Medicine
Mount Sinai School of Medicine

... “sharps” while working with human source specimens, requires immediate attention in the Employee Health Service or Emergency Department, whether the sharp is contaminated or not. These incidents must also be reported as required by OSHA. ...
printer-friendly sample test questions
printer-friendly sample test questions

... others without experiencing the sickness. The organisms that spread disease are known as A. vectors. B. mutagens. C. antibodies. D. carcinogens. 15. Which of the following is an example of a vector and the disease that it spreads? A. Bacteria and strep throat B. Shoes and athletes foot C. Mosquitoes ...
Analysis of Bottlenecks in Experimental Models of Infection
Analysis of Bottlenecks in Experimental Models of Infection

Personnel - Welcome to AVDOCS.ORG
Personnel - Welcome to AVDOCS.ORG

... Definitions Universal precautions are an approach to infection control. All human blood and certain human body fluids, including but not limited to semen, vaginal secretions and any body fluid that is visibly contaminated with blood, are treated as if known to be infectious for human immunodeficienc ...
Declining trend in transmission of drug-resistant HIV
Declining trend in transmission of drug-resistant HIV

... focus on individuals shortly after infection. Newly diagnosed patients without a known duration of infection cannot indicate the calendar year of transmission. In the literature, primary HIV-1 infections are mostly identified among people that seek health care because they suffer from acute symptoms ...
Foodborne Viruses - International Life Sciences Institute
Foodborne Viruses - International Life Sciences Institute

... everal groups of viruses may infect persons after ingestion and then are shed via stool. Of these, the Norwalk-like caliciviruses (NLV) and hepatitis A virus (HAV) are currently recognised as the most important human foodborne pathogens with regard to the number of outbreaks and people affected in t ...
Microbial Risks
Microbial Risks

... hours after ingesting the virus. The illness usually lasts one to two days, and in most cases recovery occurs without problems unless the person becomes dehydrated from the illness. This is a higher risk in very young, elderly or immunocompromised persons. Noroviruses are extremely contagious due to ...
3. Transmission of infection via clothing, household linens and laundry
3. Transmission of infection via clothing, household linens and laundry

... transmission of an infection (e.g., from an MRSA carrier, to hands, to a wound), in other cases transmission involves a number of component causes (e.g. from contaminated food, to a food contact surface, to hands, to the mouth). The likely routes of transmission via clothing and household linens are ...
A simulation model of intraherd transmission of foot and mouth
A simulation model of intraherd transmission of foot and mouth

... Abstract. Intraherd transmission of foot and mouth disease virus (FMDV) was examined using a simulation model for a hypothetical 1,000-cow dairy, assuming clinical diagnosis was made when at least 1% (10 cows) or 5% (50 cows) had clinical signs of FMD, 1 index case cow, and transition state distribu ...
The infection risks associated with clothing and household linens in
The infection risks associated with clothing and household linens in

... transmission of an infection (e.g., from an MRSA carrier, to hands, to a wound), in other cases transmission involves a number of component causes (e.g. from contaminated food, to a food contact surface, to hands, to the mouth). The likely routes of transmission via clothing and household linens are ...
Immune System - Iowa State University Digital Repository
Immune System - Iowa State University Digital Repository

... immune defense mechanisms and specific (or acquired) immune defense mechanisms. The nonspecific defense mechanisms are not antigen specific. They are present in a normal animal without previous exposure to antigen, and they are capable of responding almost immediately to an infectious agent. The maj ...
Pediatric Fever - Indiana University
Pediatric Fever - Indiana University

... – 7% thought temp could rise >110 F if left untreated – 91% believed fever could cause harmful effects • 21% brain damage • 14% death ...
Whooping cough vaccine cpt
Whooping cough vaccine cpt

... protect them from diphtheria, tetanus, and pertussis (whooping cough). But as. Whooping cough — Comprehensive overview covers symptoms, treatment of this vaccine-preventable lung infection. Fact sheets about vaccines: To improve communication about vaccines with teens and adults, the Immunization Ac ...
Hemolytic Anemias - Extracorpuscular defects
Hemolytic Anemias - Extracorpuscular defects

... complement and are optimally reactive below 370 C. It is normal to have benign cold autoantibodies, but their thermal amplitude and concentration are not high enough to cause problems. The pathologic forms can be divided into three types:  Cold agglutinin syndrome – This is idiopathic, chronic, usu ...
Study of Biologic Attributes of Cuban Dengue 2 Virus after Serial
Study of Biologic Attributes of Cuban Dengue 2 Virus after Serial

... 27 amino acid alterations scattered throughout the genome.’ However, because it is not easy to determine which changes are actually responsible for loss of virulence and which may be unimportant, it would be useful to compare the sequences of different strains at different PDK passage levels.’ One o ...
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Hepatitis B



Hepatitis B is an infectious disease caused by the hepatitis B virus (HBV) which affects the liver. It can cause both acute and chronic infections. Many people have no symptoms during the initial infection. Some develop a rapid onset of sickness with vomiting, yellowish skin, feeling tired, dark urine and abdominal pain. Often these symptoms last a few weeks and rarely does the initial infection result in death. It may take 30 to 180 days for symptoms to begin. In those who get infected around the time of birth 90% develop chronic hepatitis B while less than 10% of those infected after the age of five do. Most of those with chronic disease have no symptoms; however, cirrhosis and liver cancer may eventually develop. These complications results in the death of 15 to 25% of those with chronic disease.The virus is transmitted by exposure to infectious blood or body fluids. Infection around the time of birth or from contact with other people's blood during childhood is the most frequent method by which hepatitis B is acquired in areas where the disease is common. In areas where the disease is rare, intravenous drug use and sexual intercourse are the most frequent routes of infection. Other risk factors include working in healthcare, blood transfusions, dialysis, living with an infected person, travel in countries where the infection rate is high, and living in an institution. Tattooing and acupuncture led to a significant number of cases in the 1980s; however, this has become less common with improved sterility. The hepatitis B viruses cannot be spread by holding hands, sharing eating utensils, kissing, hugging, coughing, sneezing, or breastfeeding. The infection can be diagnosed 30 to 60 days after exposure. Diagnosis is typically by testing the blood for parts of the virus and for antibodies against the virus. It is one of five known hepatitis viruses: A, B, C, D, and E.The infection has been preventable by vaccination since 1982. Vaccination is recommended by the World Health Organization in the first day of life if possible. Two or three more doses are required at a later time for full effect. This vaccine works about 95% of the time. About 180 countries gave the vaccine as part of national programs as of 2006. It is also recommended that all blood be tested for hepatitis B before transfusion and condoms be used to prevent infection. During an initial infection, care is based on the symptoms that a person has. In those who develop chronic disease antiviral medication such as tenofovir or interferon maybe useful, however these drugs are expensive. Liver transplantation is sometimes used for cirrhosis.About a third of the world population has been infected at one point in their lives, including 240 million to 350 million who have chronic infections. Over 750,000 people die of hepatitis B each year. About 300,000 of these are due to liver cancer. The disease is now only common in East Asia and sub-Saharan Africa where between 5 and 10% of adults have chronic disease. Rates in Europe and North America are less than 1%. It was originally known as serum hepatitis. Research is looking to create foods that contain HBV vaccine. The disease may affect other great apes as well.
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