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4 Bacteria - World Health Organization
4 Bacteria - World Health Organization

... 1000 diagnosed infections leads to Guillain-Barré syndrome, a paralysis that lasts weeks to months and usually requires intensive care. Approximately 5% of patients with Guillain-Barré syndrome will die (Alketruse et al. 1999). Although rare, a number of cases are described in the literature (see fo ...
MRSA Methicillin-resistant Staphylococcus Aureus
MRSA Methicillin-resistant Staphylococcus Aureus

... Warm to the touch Full of pus or other drainage Accompanied by a fever These spots can quickly turn into deep painful abscesses that may require surgical drainage. The infection sometimes stays close to the skin, but they may also burrow deep into the body, which may cause potentially life-threateni ...
Part 3
Part 3

... quickly leads to death can hinder patients’ motivation to change high-risk behaviors such as unsafe sex and needle sharing. ...
APPENDIX III: CJD risk assessment questionnaire for patients about
APPENDIX III: CJD risk assessment questionnaire for patients about

... Risk assessment: The evaluation of an individual's personal and family history, often by using questionnaires to estimate the degree to which that person is at risk for developing certain diseases. Single use items: This is a device designated for ‘single-use’ and must not be reused. It should only ...
HIV-Infections and AIDS
HIV-Infections and AIDS

... Transmission rates are higher in undiagnosed HIV infected persons than in those who know their HIV status In one study it took 5 visits on average by the patient to the same healthcare facility before a dx of HIV infection was made Recent study in JAOA- 22% of primary care DO’s recommended HIV testi ...
2. evaluation and characterization of viral clearance procedures
2. evaluation and characterization of viral clearance procedures

... products including recombinant subunit vaccines. The safety of these products with regard to viral contamination can be reasonably assured only by the application of a virus testing program and assessment of virus removal and inactivation achieved by the manufacturing process. The type and extent of ...
PPE - Skfiretraining.org
PPE - Skfiretraining.org

... * Ensure that hand hygiene facilities are available at the point needed, e.g., sink soap &water or appropriate commercial hand disinfectant cleaner ...
Demon in the Freezer
Demon in the Freezer

... • Establish the existence of an epidemic (or outbreak) -Well the outbreak in this case appeared after the monkeys had been inoculated with two different strains of smallpox at the CDC. The Bangladesh outbreaks from 1974-1975 or small pox. 1978 outbreak of small pox- Ali Maow Maalin in Birmingham, En ...
The biological effects of interferons
The biological effects of interferons

... monoclonal antibodies raised against the target cytokine, or administration of soluble forms of its receptor that will compete with cell surface receptors for cytokine binding. • Some cytokines have already gained approval for medical use. • Many more are currently undergoing clinical or preclinical ...
of symptomatic West Nile virus infection
of symptomatic West Nile virus infection

... CCR5∆32 homozygotes, both self-reporting Caucasians from the Arizona WNV-seropositive cohort. The ages of the two CCR5∆32 homozygotes who died were 70 and 74, similar to the average age of the other 17 fatal cases (74 yr). The two CCR5∆32 homozygote fatalities represent 25 and 29% of the race-unstra ...
1. The most superficial layer of epidermis is: a) stratum germinativum
1. The most superficial layer of epidermis is: a) stratum germinativum

... d) lichen planus 49. Which of the following hypersensitivity reaction is IgE mediated? a) Type I b) Type II c) Type III d) Type IV 50. Which of the following hypersensitivity reactions is immune mediated? a) Type I b) Type II c) Type III d) Type IV 51. Grattage is useful for: a) differentiating viti ...
Practice Guidelines for the Diagnosis and
Practice Guidelines for the Diagnosis and

... aureus, the clinician should assume that the organism is resistant, because of the high prevalence of community-associated MRSA strains, and agents effective against MRSA (i.e., vancomycin, linezolid, or daptomycin) should be used (A-I). Stepdown to treatment with other agents, such as tetracycline ...
Amoebiasis Transmission And Life Cycle: A Continuous State
Amoebiasis Transmission And Life Cycle: A Continuous State

... and this may happen recursively over a period of years. He/she may also suffer from abdominal cramps, fatigue and weight loss. 3. Amebic dysentery: It is an acute intestinal amoebiasis detected at the time when Entamoeba histolytica invades the epithelial cells of the intestine and destroys them cul ...
Equine viral arteritis: Current status and prevention
Equine viral arteritis: Current status and prevention

... number of other outbreaks of the disease have since been reported from North America and Europe [5–10]. Similarly, equine arteritis virus infection of horses has been identified in countries including Australia, New Zealand, and South Africa, previously thought to be largely or completely free of th ...
Macrophages participate in host protection and the
Macrophages participate in host protection and the

... exacerbated type-1 immune response is unable to control the disease and contributes to pathological tissue damage. In contrast, SC patients produce only low levels of IFN-g and TNF-a [10]. Macrophages, the host cells for the intracellular parasite Leishmania, are crucial for the outcome of disease. ...
Influenza: Virus and Disease, Epidemics and Pandemics (Steinhoff)
Influenza: Virus and Disease, Epidemics and Pandemics (Steinhoff)

... Only agent which causes annual epidemics of disease with attack rates of 10–40% over a six-week period Historically has caused pandemics, with millions of deaths worldwide In U.S., 10,000 to 40,000 excess deaths per year and about 200,000 hospitalizations are attributed to annual influenza epidemics ...
Practice Guidelines for the Diagnosis and Management of Skin and
Practice Guidelines for the Diagnosis and Management of Skin and

... aureus, the clinician should assume that the organism is resistant, because of the high prevalence of community-associated MRSA strains, and agents effective against MRSA (i.e., vancomycin, linezolid, or daptomycin) should be used (A-I). Stepdown to treatment with other agents, such as tetracycline ...
Investigation Journal of Veterinary Diagnostic
Investigation Journal of Veterinary Diagnostic

... disease discovered in pigs from Canada in 2007. Because any outbreak of vesicular disease in pigs is assumed to be foot-andmouth disease (FMD) until confirmed otherwise, a test for diagnosing the presence of SVV would be a very useful tool. To develop the diagnostic tests for SVV infection, 5 monocl ...
docx - Center for Inference and Dynamics of Infectious Diseases
docx - Center for Inference and Dynamics of Infectious Diseases

... member(s) of an enrolled cluster who were detected via surveillance (i.e., the reason for the enrollment of the cluster into the study) as the index case(s). In humans, the complex nature of the process defining whether an infected/symptomatic individual will be detected by surveillance system can l ...
General Biosafety Training Module Biosafety Compliance Program
General Biosafety Training Module Biosafety Compliance Program

... hazardous characteristics of a known infectious or potentially infectious agent or material, the activities that can result in a person’s exposure to an agent, the likelihood that such exposure will cause a LAI, and the probable consequences of such an infection. Definition from CDC ...
Chickenpox and Shingles Information Leaflet for Patients and Visitors
Chickenpox and Shingles Information Leaflet for Patients and Visitors

... Chickenpox and Shingles. It is a viral infection which will not respond to antibiotics. Treatment should be based on reducing symptoms such as fever and itchiness. People at higher risk of developing serious complications may be given antiviral drugs such as Acyclovir. These cannot kill the virus bu ...
A Review of Pathogenic Vibrio Infections for Clinicians
A Review of Pathogenic Vibrio Infections for Clinicians

... failure. Severe infections may result in death if the dehydration is not treated aggressively with fluid and electrolyte replacement. In 1992, toxigenic V cholerae O139 (the Bengal strain) was recognized as another cause of cholera.[17] V cholerae O139, first discovered on the Indian subcontinent, h ...
Cyst Infections in Patients with Autosomal Dominant
Cyst Infections in Patients with Autosomal Dominant

... Design, setting, participants, & measurements: A retrospective study was conducted in a referral center for patients with ADPKD in Paris, France. We identified using a computerized database all patients who had ADPKD and were admitted in the nephrology department of Hôpital Necker between January 1 ...
A sandwich ELISA to detect VHSV and IPNV in turbot | SpringerLink
A sandwich ELISA to detect VHSV and IPNV in turbot | SpringerLink

... assay because the N or the VP3 proteins are the least variable antigens of the rhabdoviruses or birnaviruses, thus this assay could identify the widest range of viral isolates. The epitopes defined by the chosen Mabs were non-competitive and highly conserved in the VHSV (Sanz et a/., 1991, results n ...
Ferrets develop fatal influenza after inhaling small particle aerosols
Ferrets develop fatal influenza after inhaling small particle aerosols

... contact with secretions or fomites with oral, conjunctival and nasal mucus membranes because the virus can remain infectious on nonporous dry surfaces for up to 48 hours [16]. Since human infections with 2003 to present year H5N1 influenza viruses has been associated with high death rates and becaus ...
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Hepatitis C



Hepatitis C is an infectious disease affecting primarily the liver, caused by the hepatitis C virus (HCV). The infection is often asymptomatic, but chronic infection can lead to scarring of the liver and ultimately to cirrhosis, which is generally apparent after many years. In some cases, those with cirrhosis will go on to develop liver failure, liver cancer, or life-threatening esophageal and gastric varices.HCV is spread primarily by blood-to-blood contact associated with intravenous drug use, poorly sterilized medical equipment, and transfusions. An estimated 150–200 million people worldwide are infected with hepatitis C. The existence of hepatitis C – originally identifiable only as a type of non-A non-B hepatitis – was suggested in the 1970s and proven in 1989. Hepatitis C infects only humans and chimpanzees. It is one of five known hepatitis viruses: A, B, C, D, and E.The virus persists in the liver in about 85% of those infected. This chronic infection can be treated with medication: the standard therapy is a combination of peginterferon and ribavirin, with either boceprevir or telaprevir added in some cases. Overall, 50–80% of people treated are cured. Those who develop cirrhosis or liver cancer may require a liver transplant. Hepatitis C is the leading reason for liver transplantation, though the virus usually recurs after transplantation. No vaccine against hepatitis C is available. About 343,000 deaths due to liver cancer from hepatitis C occurred in 2013, up from 198,000 in 1990. An additional 358,000 in 2013 occurred due to cirrhosis.
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