BVGH - Who We Are - BIO Ventures for Global Health
... easier to identify clinically, the symptoms are difficult to manage in resource poor settings, contributing to a high mortality rate in these patients. When left untreated, uncomplicated malaria can rapidly progress to severe disease, especially in young children. ...
... easier to identify clinically, the symptoms are difficult to manage in resource poor settings, contributing to a high mortality rate in these patients. When left untreated, uncomplicated malaria can rapidly progress to severe disease, especially in young children. ...
eradicate it by 2010? Measles in the United Kingdom: can we
... peaked every 2-3 years, with on average 100 deaths annually.8 Routine immunisation of children with one dose of the single measles vaccine started in 1968,8 with only moderate uptake. This was replaced in 1988 by immunisation against measles, mumps, and rubella, and supplemented by a programme of me ...
... peaked every 2-3 years, with on average 100 deaths annually.8 Routine immunisation of children with one dose of the single measles vaccine started in 1968,8 with only moderate uptake. This was replaced in 1988 by immunisation against measles, mumps, and rubella, and supplemented by a programme of me ...
Bacterial Keratitis PPP - American Academy of Ophthalmology
... of Preferred Practice Pattern® guidelines that identify characteristics and components of quality eye care. Appendix 1 describes the core criteria of quality eye care. The Preferred Practice Pattern® guidelines are based on the best available scientific data as interpreted by panels of knowledgeable ...
... of Preferred Practice Pattern® guidelines that identify characteristics and components of quality eye care. Appendix 1 describes the core criteria of quality eye care. The Preferred Practice Pattern® guidelines are based on the best available scientific data as interpreted by panels of knowledgeable ...
Pertussis outbreaks in the developed countries
... The two ptxA alleles, ptx2 and ptx4 were characteristic of pre-vaccine era and predominated between 1960-1970. These alleles were replaced by ptxA1 allele in 1980 and still predominate. The vaccine allele prn1 was replaced by non-vaccine alleles prn2 and prn3. Strains with fim2-2 and fim3B have been ...
... The two ptxA alleles, ptx2 and ptx4 were characteristic of pre-vaccine era and predominated between 1960-1970. These alleles were replaced by ptxA1 allele in 1980 and still predominate. The vaccine allele prn1 was replaced by non-vaccine alleles prn2 and prn3. Strains with fim2-2 and fim3B have been ...
Approach to chronic cough in children
... • In addition to a thorough history and physical examination, a chest • radiograph should be obtained. If foreign body aspiration is suspected because of the age, clinical • presentation or history, frontal films should be obtained during both inspiration and expiration, to • evaluate for unilateral ...
... • In addition to a thorough history and physical examination, a chest • radiograph should be obtained. If foreign body aspiration is suspected because of the age, clinical • presentation or history, frontal films should be obtained during both inspiration and expiration, to • evaluate for unilateral ...
4.7 INFLUENZA 4.7.1 Virology 4.7.2 Clinical features 4.7.3
... 4.7.1 Virology The influenza viruses are single-stranded RNA orthomyxoviruses. They are classified antigenically as types A, B or C, but generally only influenza A and B cause severe disease in humans.1 Influenza viruses possess two surface glycoprotein antigens: the haemagglutinin (H), which is inv ...
... 4.7.1 Virology The influenza viruses are single-stranded RNA orthomyxoviruses. They are classified antigenically as types A, B or C, but generally only influenza A and B cause severe disease in humans.1 Influenza viruses possess two surface glycoprotein antigens: the haemagglutinin (H), which is inv ...
Preview the material
... Another oral antibiotic, fidaxomicin (Dificid), has been approved to treat C. difficile. In one study, the recurrence rate of C. difficile in people who took fidaxomicin was lower than among those who took vancomycin. However, fidaxomicin costs considerably more than metronidazole and vancomycin. Co ...
... Another oral antibiotic, fidaxomicin (Dificid), has been approved to treat C. difficile. In one study, the recurrence rate of C. difficile in people who took fidaxomicin was lower than among those who took vancomycin. However, fidaxomicin costs considerably more than metronidazole and vancomycin. Co ...
Isolation, identification and increasing importance of `free
... ‘parasitic’ form depending on the actual conditions. Two genera (Naegleria and Acanthamoeba) have become recognised as opportunist human parasites. Since the first description in 1965 of a lethal case of primary amoebic meningoencephalitis (PAM) caused by Naegleria, many more (mostly lethal) cases h ...
... ‘parasitic’ form depending on the actual conditions. Two genera (Naegleria and Acanthamoeba) have become recognised as opportunist human parasites. Since the first description in 1965 of a lethal case of primary amoebic meningoencephalitis (PAM) caused by Naegleria, many more (mostly lethal) cases h ...
2007 Annual Review
... Before we began transforming Merck’s R&D process, our clinical studies progressed more slowly than those of most of our peers. But a recent evaluation by an independent industry expert found that Merck has substantially improved its performance on this important measure. We now rank either at or n ...
... Before we began transforming Merck’s R&D process, our clinical studies progressed more slowly than those of most of our peers. But a recent evaluation by an independent industry expert found that Merck has substantially improved its performance on this important measure. We now rank either at or n ...
Sniðmát meistaraverkefnis HÍ
... virulence factor of the bacterium and highly immunogenic. Furthermore, the aim was to develop a new vaccination strategy against atypical furunculosis based on an AsaP1-toxoid. A. salmonicida possesses the LuxI/R type quorum sensing system, termed AsaI/R. The role of quorum sensing regulation of A. ...
... virulence factor of the bacterium and highly immunogenic. Furthermore, the aim was to develop a new vaccination strategy against atypical furunculosis based on an AsaP1-toxoid. A. salmonicida possesses the LuxI/R type quorum sensing system, termed AsaI/R. The role of quorum sensing regulation of A. ...
tuberculosis
... one of the oldest known communicable diseases. It is still very common in many parts of the world, but in the United States the number of cases of tuberculosis and the number of deaths from the disease that are reported each year have both been declining for several decades. Tuberculosis is a bacter ...
... one of the oldest known communicable diseases. It is still very common in many parts of the world, but in the United States the number of cases of tuberculosis and the number of deaths from the disease that are reported each year have both been declining for several decades. Tuberculosis is a bacter ...
Pathogenesis and Pathology of Bovine Pneumonia
... resistant to phagocytosis and complement-mediated serum killing.26 H somni produces histamine, which in conjunction with anti–major outer membrane protein IgE, may account for early respiratory lesions.12,27,28 Recently, biofilm production by H somni within the host was documented, which allows the ...
... resistant to phagocytosis and complement-mediated serum killing.26 H somni produces histamine, which in conjunction with anti–major outer membrane protein IgE, may account for early respiratory lesions.12,27,28 Recently, biofilm production by H somni within the host was documented, which allows the ...
originalni naučni radovi
... during their reproductive age (2), which is the value slightely higher than ours. We should bear in mind that the frequency of bacterial vaginosis and other sexually transmitted diseases significantly depends on the characteristics of the examined population, as well as on the applied diagnostic met ...
... during their reproductive age (2), which is the value slightely higher than ours. We should bear in mind that the frequency of bacterial vaginosis and other sexually transmitted diseases significantly depends on the characteristics of the examined population, as well as on the applied diagnostic met ...
Host-Pathogen Interactions: The Attributes of Virulence
... of molecular tools to search for genes that may be essential for virulence [38]. The quest for the molecular genetic basis of virulence has spawned the development of technology to look for multiple genes that may ultimately unravel the regulation of virulence at the genetic level [39–42]. Microbial ...
... of molecular tools to search for genes that may be essential for virulence [38]. The quest for the molecular genetic basis of virulence has spawned the development of technology to look for multiple genes that may ultimately unravel the regulation of virulence at the genetic level [39–42]. Microbial ...
Molecular Characterization of Syphilis in Patients in Canada
... The three treponemal gene PCR assays (tpp47, bmp, and polA) gave concordant results in all specimens collected from syphilis patients, regardless of the specimen types (blood or swab) or the stages of disease (primary or secondary). Nineteen (36%) of the 53 specimens were positive by PCR. Overall, 1 ...
... The three treponemal gene PCR assays (tpp47, bmp, and polA) gave concordant results in all specimens collected from syphilis patients, regardless of the specimen types (blood or swab) or the stages of disease (primary or secondary). Nineteen (36%) of the 53 specimens were positive by PCR. Overall, 1 ...
UK SMI Title goes here
... This 'CMV serology' SMI does not cover the diagnosis of CMV infection in immunocompromised individuals (including HIV-infected, graft recipient, immunosuppressive treatment). Molecular assays (or pp65 antigenemia) are preferred for diagnosis and monitoring of CMV infection and related disease in thi ...
... This 'CMV serology' SMI does not cover the diagnosis of CMV infection in immunocompromised individuals (including HIV-infected, graft recipient, immunosuppressive treatment). Molecular assays (or pp65 antigenemia) are preferred for diagnosis and monitoring of CMV infection and related disease in thi ...
Top Ten Things That Don`t Cause Arthritis
... round shape due to avascular necrosis, arthritis may develop. Other drugs (such as alendronate or phenobarbital) may cause bone or joint pain but not arthritis. Similarly, diuretic drugs (“ water pills” ) may increase the risk of gout, but it isn’ t the cause of the disease. Finally, a rare conditio ...
... round shape due to avascular necrosis, arthritis may develop. Other drugs (such as alendronate or phenobarbital) may cause bone or joint pain but not arthritis. Similarly, diuretic drugs (“ water pills” ) may increase the risk of gout, but it isn’ t the cause of the disease. Finally, a rare conditio ...
Imogam® Rabies – HT
... Imogam® Rabies – HT should be injected as promptly as possible after exposure along with the first dose of vaccine. If initiation of treatment is delayed for any reason, Imogam® Rabies – HT and the first dose of vaccine should still be given, regardless of the interval between exposure and treatment ...
... Imogam® Rabies – HT should be injected as promptly as possible after exposure along with the first dose of vaccine. If initiation of treatment is delayed for any reason, Imogam® Rabies – HT and the first dose of vaccine should still be given, regardless of the interval between exposure and treatment ...
Infectious Diseases : a Clinical Short Course
... our Despite dire warnings that we are approaching the end of the antibiotic era, the incidence of antibiotic-resistant bacteria continues to rise. The proportions of penicillin-resistant Streptococcus pneumoniae, hospital-acquired methicillin-resistant Staphylococcus aureus (MRSA), and vancomycin-re ...
... our Despite dire warnings that we are approaching the end of the antibiotic era, the incidence of antibiotic-resistant bacteria continues to rise. The proportions of penicillin-resistant Streptococcus pneumoniae, hospital-acquired methicillin-resistant Staphylococcus aureus (MRSA), and vancomycin-re ...
Rabies Immune Globulin (Human) USP Imogam Rabies – HT
... Imogam® Rabies – HT should be injected as promptly as possible after exposure along with the first dose of vaccine. If initiation of treatment is delayed for any reason, Imogam® Rabies – HT and the first dose of vaccine should still be given, regardless of the interval between exposure and treatment ...
... Imogam® Rabies – HT should be injected as promptly as possible after exposure along with the first dose of vaccine. If initiation of treatment is delayed for any reason, Imogam® Rabies – HT and the first dose of vaccine should still be given, regardless of the interval between exposure and treatment ...
anthrax - sfcdcp
... biological threats. Anthrax has been weaponized and used. It can be fairly easily disseminated and causes illness and death. Of the potential ways that B. anthracis could be used as a biological weapon, an aerosol release is expected to have the most severe medical and public health outcomes.1 ...
... biological threats. Anthrax has been weaponized and used. It can be fairly easily disseminated and causes illness and death. Of the potential ways that B. anthracis could be used as a biological weapon, an aerosol release is expected to have the most severe medical and public health outcomes.1 ...
Medical Bacteriology
... to changes in air, winds, water, climate, food, nature of soil and habits of people. Varro (117-26 BC)said a theory that disease was caused by animated particles invisible to naked eye but which were carried in the air through the mouth and nose into the body. Fracastorius (1500 G.C.) proposed that ...
... to changes in air, winds, water, climate, food, nature of soil and habits of people. Varro (117-26 BC)said a theory that disease was caused by animated particles invisible to naked eye but which were carried in the air through the mouth and nose into the body. Fracastorius (1500 G.C.) proposed that ...
Anthrax JULY 2008 - San Francisco Bay Area Advanced Practice
... has decreased from 86-95% to 45% for inhalational anthrax, 5-20% to less than 1% for cutaneous anthrax, and 25-60% to 12% for gastrointestinal anthrax. Anthrax meningitis case-fatality rates approach 95% even with antibiotic treatment.2, 3, 16 In the event of bioterrorism, the method of disseminatio ...
... has decreased from 86-95% to 45% for inhalational anthrax, 5-20% to less than 1% for cutaneous anthrax, and 25-60% to 12% for gastrointestinal anthrax. Anthrax meningitis case-fatality rates approach 95% even with antibiotic treatment.2, 3, 16 In the event of bioterrorism, the method of disseminatio ...
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... micronucleus (MI) of Paramecium species (for review see Görtz and Schmidt, 2005; Fokin and Görtz, 2009), as well as the MA of Frontonia (Fokin et al., 2006; Ferrantini et al., 2007). All HLB live in an obligate endosymbiosis with their hosts, and have variable degrees of nuclear and host specificity ...
... micronucleus (MI) of Paramecium species (for review see Görtz and Schmidt, 2005; Fokin and Görtz, 2009), as well as the MA of Frontonia (Fokin et al., 2006; Ferrantini et al., 2007). All HLB live in an obligate endosymbiosis with their hosts, and have variable degrees of nuclear and host specificity ...
eMERGE Network Project Proposal for
... As an extension to single marker, multimarker and epistasic associations, we will consider gene set enrichment to identify pathway association. Using Gene Set Enrichment Analysis (GSEA release 2.0.4) software we will identify enriched gene sets representing biological pathways (Subramanian, 2005). P ...
... As an extension to single marker, multimarker and epistasic associations, we will consider gene set enrichment to identify pathway association. Using Gene Set Enrichment Analysis (GSEA release 2.0.4) software we will identify enriched gene sets representing biological pathways (Subramanian, 2005). P ...
Neisseria meningitidis
Neisseria meningitidis, often referred to as meningococcus, is a gram negative bacterium that can cause meningitis and other forms of meningococcal disease such as meningococcemia, a life-threatening sepsis. The bacterium is referred to as a coccus because it is round, and more specifically, diplococcus because of its tendency to form pairs. About 10% of adults are carrier of the bacteria in their nasopharynx. As an exclusively human pathogen it is the main cause of bacterial meningitis in children and young adults, causing developmental impairment and death in about 10% of cases. It causes the only form of bacterial meningitis known to occur epidemically, mainly in Africa and Asia.N. meningitidis is spread through saliva and respiratory secretions during coughing, sneezing, kissing, and chewing on toys. It infects the cell by sticking to it with long thin extensions called pili and the surface-exposed proteins Opa and Opc and has several virulence factors.