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qPCR DNA Extraction and Inhibition Control
qPCR DNA Extraction and Inhibition Control

... The spiked SPC co-purifies during extraction and co-amplifies with the target nucleic acid. In conjunction with your target system, the SPC allows you to identify positive and negative samples for a specific target sequence. During amplification, the sample and SPC generate reporter fluorescence sig ...
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RNA and Protein Synthesis
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... with good descriptions of those terms. A total of 6 points were earned from the description of how a plasmid can be modified. The first point was earned for providing the definition of the plasmid. The next 3 points were earned for the description of the cutting of the DNA: the plasmid and the gene ...
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DNA supercoil



DNA supercoiling refers to the over- or under-winding of a DNA strand, and is an expression of the strain on that strand. Supercoiling is important in a number of biological processes, such as compacting DNA. Additionally, certain enzymes such as topoisomerases are able to change DNA topology to facilitate functions such as DNA replication or transcription. Mathematical expressions are used to describe supercoiling by comparing different coiled states to relaxed B-form DNA.As a general rule, the DNA of most organisms is negatively supercoiled.
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