Antigenic diversity of Theileria major piroplasm surface protein gene
... cattle were normal clinically and on hematological examination. In this study, we used PCR-RLFP to subclassify type B, as described previously [5,12]. The major pattern identified was type B1 (11 of 17), and 5 of the 17 isolates were a mix of types B1 and B2. One sample exhibited a new pattern, with ...
... cattle were normal clinically and on hematological examination. In this study, we used PCR-RLFP to subclassify type B, as described previously [5,12]. The major pattern identified was type B1 (11 of 17), and 5 of the 17 isolates were a mix of types B1 and B2. One sample exhibited a new pattern, with ...
Evolutionary Origin and Adaptive Function of Meiosis
... Development of competence in Bacillus subtilis requires expression of about 40 genes (Solomon and Grossman, 1996). The exogenous DNA integrated into the recipient chromosome is usually (with rare exceptions) derived from another bacterium of the same species, and is thus homologous to the resident c ...
... Development of competence in Bacillus subtilis requires expression of about 40 genes (Solomon and Grossman, 1996). The exogenous DNA integrated into the recipient chromosome is usually (with rare exceptions) derived from another bacterium of the same species, and is thus homologous to the resident c ...
Analysis of the first polar body: preconception genetic
... stage. Finally, aspiration of the first polar body should have no detrimental effects on fertilization or embryonic development, since the first polar body is not involved in these processes. Preconception diagnosis by the removal and genetic analysis of the first polar body can be applied to any ge ...
... stage. Finally, aspiration of the first polar body should have no detrimental effects on fertilization or embryonic development, since the first polar body is not involved in these processes. Preconception diagnosis by the removal and genetic analysis of the first polar body can be applied to any ge ...
Identifying a Novel Isoform of the AZIN1 Gene by Combining High
... reading frame that would change the terminus of the subsequent protein from Ser-Asp-Glu-Asp-stop to PheArg-stop. Follow-up studies could validate this finding on the protein level and then measure gene expression of this new isoform in various tissues, subjects, and time-points. Moreover, the method ...
... reading frame that would change the terminus of the subsequent protein from Ser-Asp-Glu-Asp-stop to PheArg-stop. Follow-up studies could validate this finding on the protein level and then measure gene expression of this new isoform in various tissues, subjects, and time-points. Moreover, the method ...
Diversity of DNA methyltransferases that recognize asymmetric
... and structural studies are required to confirm the relevance of this dimerization. The extent of subunit contacts observed in the crystal structure of M.MboIIA suggested that the two molecules in the asymmetric unit represent a biologically relevant dimer. In M.AhdI, two copies of the AhdIS subunit ...
... and structural studies are required to confirm the relevance of this dimerization. The extent of subunit contacts observed in the crystal structure of M.MboIIA suggested that the two molecules in the asymmetric unit represent a biologically relevant dimer. In M.AhdI, two copies of the AhdIS subunit ...
Mutations of the ret protooncogene in German multiple
... creating a new restriction site had been identified in one family member, the amplified DNA fragments from other members of this family were usually analyzed solely by restriction enzyme analysis. Restriction enzyme digests were carried out according to the instructions of the supplier. Analysis of ...
... creating a new restriction site had been identified in one family member, the amplified DNA fragments from other members of this family were usually analyzed solely by restriction enzyme analysis. Restriction enzyme digests were carried out according to the instructions of the supplier. Analysis of ...
The Structures of DNA and RNA
... he discovery that DNA is the prime genetic molecule, carrying all the hereditary information within chromosomes, immediately focused attention on its structure. It was hoped that knowledge of the structure would reveal how DNA carries the genetic messages that are replicated when chromosomes divide ...
... he discovery that DNA is the prime genetic molecule, carrying all the hereditary information within chromosomes, immediately focused attention on its structure. It was hoped that knowledge of the structure would reveal how DNA carries the genetic messages that are replicated when chromosomes divide ...
Genetic Testing For FMR1 Mutations (Including
... with reflex to FMR1 diagnostic, FMR1 diagnostic, and FMR1 fetal diagnostic is 99%.8,9 Clinical sensitivity and specificity is 99% for premutation and full mutation alleles. Diagnostic errors can occur due to rare sequence variations. DNA studies are used to test for FXS. Genotypes of individuals wit ...
... with reflex to FMR1 diagnostic, FMR1 diagnostic, and FMR1 fetal diagnostic is 99%.8,9 Clinical sensitivity and specificity is 99% for premutation and full mutation alleles. Diagnostic errors can occur due to rare sequence variations. DNA studies are used to test for FXS. Genotypes of individuals wit ...
CSE 181 Project guidelines
... Uncovering the code • Scientists conjectured that proteins came from DNA; but how did DNA code for proteins? • If one nucleotide codes for one amino acid, then there’d be 41 amino acids • However, there are 20 amino acids, so at least 3 bases codes for one amino acid, since 42 = 16 and 43 = 64 • Thi ...
... Uncovering the code • Scientists conjectured that proteins came from DNA; but how did DNA code for proteins? • If one nucleotide codes for one amino acid, then there’d be 41 amino acids • However, there are 20 amino acids, so at least 3 bases codes for one amino acid, since 42 = 16 and 43 = 64 • Thi ...
method, a successful experiment must be verified by Southern blots
... purified DNA has provided simple, rapid methods for the molecular cloning of mutant forms of genes ("eviction" of mutant genes) and for the introduction into yeast of mutant genes constructed in vitro ("transplacement" of mutant genes). This chapter will place these techniques in a conceptual framew ...
... purified DNA has provided simple, rapid methods for the molecular cloning of mutant forms of genes ("eviction" of mutant genes) and for the introduction into yeast of mutant genes constructed in vitro ("transplacement" of mutant genes). This chapter will place these techniques in a conceptual framew ...
12-4 Mutations
... mutations can alter a protein so much that it is unable to perform its normal ...
... mutations can alter a protein so much that it is unable to perform its normal ...
PraderWilli syndrome resulting from an unbalanced translocation
... deletion was between 6.3 and 7.4 Mb as determined by array CGH analysis. The molecular breakpoint determined by array CGH was within 5p15.31 based on the UCSC draft human genome sequence. Furthermore, it was possible to localize the breakpoint to a region less than 1 Mb defined by the map position o ...
... deletion was between 6.3 and 7.4 Mb as determined by array CGH analysis. The molecular breakpoint determined by array CGH was within 5p15.31 based on the UCSC draft human genome sequence. Furthermore, it was possible to localize the breakpoint to a region less than 1 Mb defined by the map position o ...
Module 7 – Microbial Molecular Biology and Genetics
... thymine in RNA and differs from thymine by lacking a methyl group on its ring. Uracil is not usually found in DNA, occurring only as a breakdown product of cytosine. In addition to RNA and DNA a large number of artificial nucleic acid analogues have also been created to study the proprieties of nucl ...
... thymine in RNA and differs from thymine by lacking a methyl group on its ring. Uracil is not usually found in DNA, occurring only as a breakdown product of cytosine. In addition to RNA and DNA a large number of artificial nucleic acid analogues have also been created to study the proprieties of nucl ...
Sex Chromosomal Transposable Element Accumulation
... comparison, 172 Alu elements from four autosomal regions were identified, and the divergences were similarly calculated (fig. 3A). As expected, the oldest class, AluJ, has the highest level of divergence, while the youngest class, AluY, has the lowest. Furthermore, Alu elements of all classes locate ...
... comparison, 172 Alu elements from four autosomal regions were identified, and the divergences were similarly calculated (fig. 3A). As expected, the oldest class, AluJ, has the highest level of divergence, while the youngest class, AluY, has the lowest. Furthermore, Alu elements of all classes locate ...
PDF
... component of epigenetics. It must be clarified that two types of epigenetic inheritance are usually referred to: (i) epigenetic marks, which can be inherited in the soma line as these marks are conserved during mitosis (Jablonka and Raz, 2009), and (ii) transgenerational epigenetic inheritance via th ...
... component of epigenetics. It must be clarified that two types of epigenetic inheritance are usually referred to: (i) epigenetic marks, which can be inherited in the soma line as these marks are conserved during mitosis (Jablonka and Raz, 2009), and (ii) transgenerational epigenetic inheritance via th ...
An Introduction to Genetic Analysis Chapter21 Extranuclear Genes
... cells can obtain ATP by fermentation, which does not rely on the mitochondrial oxidative phosphorylation system, so yeast with these drastically deleted genotypes can survive, albeit at a reduced activity level. Petites in which part of the mtDNA has been deleted regenerate full-sized mtDNA molecule ...
... cells can obtain ATP by fermentation, which does not rely on the mitochondrial oxidative phosphorylation system, so yeast with these drastically deleted genotypes can survive, albeit at a reduced activity level. Petites in which part of the mtDNA has been deleted regenerate full-sized mtDNA molecule ...
Comparison of the Detection Limits of the Culture and PCR Methods
... The prevalence levels of Campylobacter, Y. enterocolitica, and C. difficile are about 10.8%, 1.2%, and 21%, respectively, in stool samples of patients with gastroenteritis in developing countries (28-30). These rates are lower than those reported for developed countries (4, 31). Despite differences ...
... The prevalence levels of Campylobacter, Y. enterocolitica, and C. difficile are about 10.8%, 1.2%, and 21%, respectively, in stool samples of patients with gastroenteritis in developing countries (28-30). These rates are lower than those reported for developed countries (4, 31). Despite differences ...
Monitoring MDG 5: Interpreting Maternal Mortality Estimates*
... births and deaths. Household survey – The Demographic and Health Surveys (DHS) is a source of maternal mortality data for several low income countries. However, it measures pregnancy-related deaths—not maternal deaths; furthermore, female deaths might be underreported. Census – National census is a ...
... births and deaths. Household survey – The Demographic and Health Surveys (DHS) is a source of maternal mortality data for several low income countries. However, it measures pregnancy-related deaths—not maternal deaths; furthermore, female deaths might be underreported. Census – National census is a ...
Adaptive value of sex in microbial pathogens
... 1995; Gandon and Otto, 2007). Data from pathogens bearing on the host–parasite model will be discussed below. Because of these and other problems with the negative epistasis model, some workers in this area favor selection and chance effects in finite populations as the main sources of genetic assoc ...
... 1995; Gandon and Otto, 2007). Data from pathogens bearing on the host–parasite model will be discussed below. Because of these and other problems with the negative epistasis model, some workers in this area favor selection and chance effects in finite populations as the main sources of genetic assoc ...
Fighting the good cause: meaning, purpose
... would fertilize my mother’s egg. There is a single causal narrative out of the past but a beyond astronomical proliferation of possibilities into the future. One can explain with much greater confidence than one can predict. Taking a step further back fro ...
... would fertilize my mother’s egg. There is a single causal narrative out of the past but a beyond astronomical proliferation of possibilities into the future. One can explain with much greater confidence than one can predict. Taking a step further back fro ...
Frequency of two disease-associated mutations in Cavalier King
... mutant alleles respectively, we can apply the equation p2 + 2pq + q2 = 1 to our frequencies (Tables 4 & 5 above). We are particularly interested in finding out the percentage of carriers in the overall population. Using our ...
... mutant alleles respectively, we can apply the equation p2 + 2pq + q2 = 1 to our frequencies (Tables 4 & 5 above). We are particularly interested in finding out the percentage of carriers in the overall population. Using our ...
Apolipoprotein E Allele Distribution in Trisomy
... apolipoprotein E (apoE) allele e4 among mothers of children diagnosed with Down syndrome. We studied the prevalence of apoE alleles among 56 conceptuses with trisomy 13, trisomy 18, or trisomy 21. The presence of the 3 most common apoE alleles (e2, e3, e4) was determined by polymerase chain reaction ...
... apolipoprotein E (apoE) allele e4 among mothers of children diagnosed with Down syndrome. We studied the prevalence of apoE alleles among 56 conceptuses with trisomy 13, trisomy 18, or trisomy 21. The presence of the 3 most common apoE alleles (e2, e3, e4) was determined by polymerase chain reaction ...
No Slide Title
... • Abnormalities in the eyes were observed in the XPA-/knockouts, but not in the normal or heterozygous mice. ...
... • Abnormalities in the eyes were observed in the XPA-/knockouts, but not in the normal or heterozygous mice. ...