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the genetics of viruses and bacteria
the genetics of viruses and bacteria

... Viruses and bacteria are the simplest biological systems - microbial models where scientists find life’s fundamental molecular mechanisms in their most basic, accessible forms. ...
A one-step cloning method for the construction of somatic cell gene
A one-step cloning method for the construction of somatic cell gene

... and then numerous cloning steps. It is an extremely time-consuming process and limited by the available unique restriction enzyme sites in the vector and in the two amplified homologous fragments. Phage-based Escherichia coli homologous recombination systems [7-9] have been developed that now make i ...
The Difference Makers
The Difference Makers

... 5. What happens to make a live transposon a “transposon fossil”? What are a few positive outcomes that have come from “transposon fossils”? Possible student response: If the mobile elements of a transposon are not fully copied, either because of partial copying or a mutation, the transposon will n ...
Comprehensive analysis of CpG islands in human
Comprehensive analysis of CpG islands in human

... program comes up with 14,062 CpG islands, more than half of which are Alu repeats (not true CpG islands). Using stricter criteria—minimum length of 500 bp, G + C content of at least 55%, and obs/exp of at least .65—Takai and Jones run their program again and come up with 1,101 CpG islands. Their res ...
SNPs in association studies
SNPs in association studies

... replications  Reproducibility score modeled as the ratio of successful replications over the total number of subsequent studies. ...
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EPICENTRE Revolutionizes Cloning by Introducing CopyControl
EPICENTRE Revolutionizes Cloning by Introducing CopyControl

Biology Partnership Grant Lesson Plan 1
Biology Partnership Grant Lesson Plan 1

... instruction. The teacher informs the students that the set of instructions called DNA makes up the recipe for traits in all living organisms including us. The information in a DNA strand is grouped into small segments. Each segment is made of even smaller units just like a recipe – In a recipe each ...
Diagnosis of Hereditary Disease in the Purebred Dog
Diagnosis of Hereditary Disease in the Purebred Dog

... In some instances it may be that a disease gene is very widespread in within a breed. One of the most notable examples of this is CEA. At this stage for some breeds, it may be necessary to carry out matings with known carriers or affected animals, otherwise the breed will become nonexistent. Because ...
Molecular Genetics of Inherited Disorders
Molecular Genetics of Inherited Disorders

... A gene is composed of two major parts, a sequence transcribed into RNA and sequences not transcribed but which is necessary for the expression of the gene activity. The transcribed sequence can be further subdivided into the coding and non-coding sequences. The coding sequence directs the sequence o ...
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M-protein and other intrinsic virulence factors of Streptococcus

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The role of epigenetics in the regulation of gene transcription
The role of epigenetics in the regulation of gene transcription

... recruit the HDAC complex, which deacetylates the histone tails, which then become available for methylation by the histone methyltransferase (HMT) ...
BMC Genomics
BMC Genomics

... cumulative TA-skew presented a V-shape, which segments were interrupted by several steep slopes regions (SSRs), indicative of a different nucleotide composition bias. Each S. pyogenes genome contained up to nine individual SSRs, encompassing all described strain-specific prophages. In addition, each ...
Using comparative genomic hybridization to
Using comparative genomic hybridization to

... Suzy CP Renn*†1, Heather E Machado†1, Albyn Jones2, Kosha Soneji3, Rob J Kulathinal4 and Hans A Hofmann5 ...
Genetic Disorder Project - Mad River Local Schools
Genetic Disorder Project - Mad River Local Schools

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Indigenous peoples and the morality of the Human Genome
Indigenous peoples and the morality of the Human Genome

... the HGP. These preexisting targeted research programmes were integrated into the HGP at its inception, and for some years provided the basis for most scientific advances. However, a variety of random ordering and sequencing strategies (such as those which used a set of large families to map random s ...
Exam 3 Review B - Iowa State University
Exam 3 Review B - Iowa State University

... 15. The concept that an amino acid can be specified by more than one codon is known as a. Colinearity b. Degeneracy c. Isoaccepting d. Synonymity 16. This helps set the reading frame for translation a. Shine-Dalgarno sequence b. Kozak sequence c. Initiation codon d. 5’ cap 17. Which of the followin ...
IJBT 10(2) 178-182
IJBT 10(2) 178-182

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... cells in the pancreas specialize in secreting insulin to control blood sugar) then many copies of the required mRNA are created. image from: ...
chapter 17 and 18 study guide
chapter 17 and 18 study guide

... Promoter? A specific nucleotide sequence in the DNA that binds RNA polymerase, positioning it to start transcribing RNA at the appropriate place Repressor? A protein that inhibits gene transcription; in prokaryotes repressors bind to the DNA in or near the promoter; in eukaryotes repressors can bind ...
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S5. Untangling the central dogma- Extensions on

... made up of bundles of fibers and a group of interdependent proteins along the membrane surrounding each fiber helps to keep muscle cells working properly. Dystrophin is one of the proteins involved in this process. When the amino acid sequence of dystrophin is changed due to a mutation, muscles do n ...
Postdoctoral researcher - A conditional approach to probing ATR
Postdoctoral researcher - A conditional approach to probing ATR

... Candidates should have strong documentation, oral and interpersonal skills. The ideal candidate would have experience in the field of cell cycle regulation and/or genome stability and would be well placed to apply for independent personal fellowships. ...
Protein Synthesis Activity
Protein Synthesis Activity

... 1. Colour your DNA strand so that the bases are different colours but all of the bases of the same type are the same colour. 2. Cut out the DNA and mRNA molecules. (mRNA is messenger RNA) TRANSCRIPTION: occurs in the nucleus 3. Create the nucleus on the left side of your desk by placing your DNA str ...
Biotechnology
Biotechnology

... 4. Tissue culture: Tissue culture of both plant and animal cells. These are used for Micropropagation of elite or exotic materials (such as orchids), production of useful compounds such as taxol (the widely used anticancer drug) and vanillin, and preparation in the laboratory of “natural” tissues su ...
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Genomics

Genomics is a discipline in genetics that applies recombinant DNA, DNA sequencing methods, and bioinformatics to sequence, assemble, and analyze the function and structure of genomes (the complete set of DNA within a single cell of an organism). Advances in genomics have triggered a revolution in discovery-based research to understand even the most complex biological systems such as the brain. The field includes efforts to determine the entire DNA sequence of organisms and fine-scale genetic mapping. The field also includes studies of intragenomic phenomena such as heterosis, epistasis, pleiotropy and other interactions between loci and alleles within the genome. In contrast, the investigation of the roles and functions of single genes is a primary focus of molecular biology or genetics and is a common topic of modern medical and biological research. Research of single genes does not fall into the definition of genomics unless the aim of this genetic, pathway, and functional information analysis is to elucidate its effect on, place in, and response to the entire genome's networks.
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