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High Frequency of Recombination (Hfr)
High Frequency of Recombination (Hfr)

... Recombination Requires Crossing over Double Crossover ...
Quality Control of High-‐Throughput Sequencing data
Quality Control of High-‐Throughput Sequencing data

... Tech2  interval  extends  to  the  intron  (250  bp  upstream,  also  void  of  coverage)   Caveat:  raw  sequence  data  displayed  here  are  by  defini;on  not  normalized,  so  comparisons  should  be  limited  to  rela;ve   amounts ...
Identifying Chromosomal Abnormalities Using Infinium
Identifying Chromosomal Abnormalities Using Infinium

... Illumina, illuminaDx, Solexa, Making Sense Out of Life, Oligator, Sentrix, GoldenGate, GoldenGate Indexing, DASL, BeadArray, Array of Arrays, Infinium, BeadXpress, VeraCode, IntelliHyb, iSelect, CSPro, GenomeStudio, Genetic Energy, and HiSeq are registered trademarks or trademarks of Illumina, Inc. ...
Investigation of the premelanosome protein
Investigation of the premelanosome protein

... Re-sequencing of parts of the rabbit PMEL gene and identification of intronic polymorphisms To identify polymorphisms that could be useful to evaluate their possible co-segregation with the black-blue spotted phenotype in the F1 families, fragments of the rabbit PMEL gene including 4 out of 11 exons ...
Biology 120 Mock Final Examination
Biology 120 Mock Final Examination

... 46. The alleles for flower colour and stem length segregate together. An unknown cross results in 43% of the offspring having red flowers and a long stem, 44% white flowers and a short stem, 7% red flowers and a short stem, and 6% white flowers and a long stem. Which phenotypes are the parental phen ...
High Frequency of Recombination (Hfr)
High Frequency of Recombination (Hfr)

... Recombination Requires Crossing over Double Crossover ...
Exam 2 (pdf - 90.37kb)
Exam 2 (pdf - 90.37kb)

... • Check that your name and student number as printed on your answer sheet for multiple-choice questions are correct, and sign your name in the space provided to verify this. • All written responses must be in English. At the end of the examination • Place the answer sheet for multiple-choice questio ...
D. PCR - Pass the FracP
D. PCR - Pass the FracP

... Question 22 6. Which of the following is/are true of autosomal recessive disorders? A. All offspring of two individuals with autosomal recessive disorder will be affected. B. Genetic counselling for members of affected families is based on the assumption that mutation rates are high C. The risk of h ...
State v. Johnson
State v. Johnson

... because the alleles chosen to create the DNA profile with the RFLP protocol are non-coding, that is, they are not responsible for producing any observable characteristic. See NRC report at 77; Krawczak & Schmidtke, supra, at 74; Maj. Douglas A. Dribben, DNA Statistical Evidence and the "Ceiling Prin ...
A. niger
A. niger

FnrP interactions with the Pasteurella haemolytica leukotoxin promoter
FnrP interactions with the Pasteurella haemolytica leukotoxin promoter

... region of the P1 leukotoxin promoter. Binding of FnrP at either half-site could a¡ect leukotoxin expression by excluding transcription initiated at the leukotoxin P1 promoter. Binding at the downstream half-site could inhibit binding of another regulatory protein at the overlapping near-IHF site. Mo ...
A Genetic Linkage Map for the Zebrafish
A Genetic Linkage Map for the Zebrafish

BLAST - AP Biology
BLAST - AP Biology

... Comparing DNA Sequences to Understand Evolutionary Relationships with BLAST How can bioinformatics be used as a tool to determine evolutionary relationships and to better understand genetic diseases? ■ Background Between 1990-2003, scientists working on an international research project known as the ...
Understanding Evolutionary Relationships with
Understanding Evolutionary Relationships with

Get cached PDF
Get cached PDF

... dogs have yet to be identified at the molecular level, with the exception of that for the yellow coat color [2]. Genes responsible for white spotting in mice and horses and for hypopigmentation defects in humans have been identified. One of these, EDNRB, encoding the endothelin B receptor, causes wh ...
Genetic identification of eleven aquatic bacteria using the 16S rDNA
Genetic identification of eleven aquatic bacteria using the 16S rDNA

... (Baron, 1996). Nucleic acids assays include methods for identification that consists on the determination of the relative proportion of guanine and cytosine, however, this method does not rely on the linear arrangement of the nucleotides, and therefore, its accuracy is low. DNA and RNA homology expe ...
Ultraconserved Elements in the Human Genome
Ultraconserved Elements in the Human Genome

... cases there is clear mRNA or EST evidence that the coding region overlapped by the element is alternatively spliced in human. These include alternatively spliced exons of genes EIF2C1, BCL11A, EVI1, ZFR, CLK4, HNRPH1, and DDX5, as well as GRIA3. In none of the other cases could we find evidence that ...
Crystal structure of human MTH1 and the 8-oxo-dGMP product complex
Crystal structure of human MTH1 and the 8-oxo-dGMP product complex

... Oxygen radicals are produced as a byproduct of cellular metabolism. Reactive oxygen species (ROS) cause damage not only to the DNA directly, but also to the free bases in the nucleotide pool, resulting in for instance 8-oxo-dGTP, which can be misincorporated into the DNA and if unrepaired can cause ...
cached copy
cached copy

... We can manipulate DNA with many enzymes, such as restriction enzymes (which cleave DNA at particular sites) or ligases (which catalyze the joining of two molecules by covalent bonds — sturdy chemical bonds that involve the sharing of pairs of electrons between atoms). These tools can be used to make ...
Plasmodium malariae and P. ovale genomes provide insights into
Plasmodium malariae and P. ovale genomes provide insights into

(FA-SAT) in a Cat Fibrosarcoma Might Be Related to Chromosomal
(FA-SAT) in a Cat Fibrosarcoma Might Be Related to Chromosomal

... All these suppositions, at this stage of the work, are speculative. To attest them, the verification of additional kinetochore formation at these regions is needed. Also important would be the analysis of the marker chromosome’s clonal evolution, besides the concomitant study of the amplified repeti ...
Advanced Plant Technology Program Vocabulary
Advanced Plant Technology Program Vocabulary

... Genetics (noun): The study of genes and their effects on individuals. 
 Genome (noun): All of the genetic material an organism possesses. Genome-wide association study (GWAS) (noun): An examination of the genetic variation between individuals (see SNPs) to see if the variation is associated with a t ...
Gene Duplication and Evolution
Gene Duplication and Evolution

... 66% for Caenorhabditis elegans, and 65% for Saccharomyces cerevisiae. (iii) The tails include old and ancient duplications. The heterogeneity of the age distribution in figure 2 of (1) suggests that the short half-life calculated from young duplicate-gene pairs cannot be extended to most pairs. Afte ...
The CHARGE Targeted Sequencing Study
The CHARGE Targeted Sequencing Study

... been associated in genome-wide association studies with fasting glucose and insulin (FI). In the Cohorts for Heart and Aging Research in Genomic Epidemiology Targeted Sequencing Study, we sequenced 5 gene regions at 11p11.2 to identify rare, potentially functional variants influencing fasting glucos ...
Natural selection on the molecular level
Natural selection on the molecular level

... The rate of substitution and the degree of polymorphism are too high to be explained by selection alone ...
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Genomics

Genomics is a discipline in genetics that applies recombinant DNA, DNA sequencing methods, and bioinformatics to sequence, assemble, and analyze the function and structure of genomes (the complete set of DNA within a single cell of an organism). Advances in genomics have triggered a revolution in discovery-based research to understand even the most complex biological systems such as the brain. The field includes efforts to determine the entire DNA sequence of organisms and fine-scale genetic mapping. The field also includes studies of intragenomic phenomena such as heterosis, epistasis, pleiotropy and other interactions between loci and alleles within the genome. In contrast, the investigation of the roles and functions of single genes is a primary focus of molecular biology or genetics and is a common topic of modern medical and biological research. Research of single genes does not fall into the definition of genomics unless the aim of this genetic, pathway, and functional information analysis is to elucidate its effect on, place in, and response to the entire genome's networks.
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