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`Genes` Like That, Who Needs an Environment?
`Genes` Like That, Who Needs an Environment?

... Carroll 2004). It is well known that a single site can be bound by different transcription factors, which often bind cooperatively, and also that multiple cis-regulatory modules involved in development often act independently of each other (Stern 2003, 146). The seeming lack of strong sequence const ...
Comparative genomics and Target discovery
Comparative genomics and Target discovery

... disease related, 30 random) of diverse gene density and nonexonic conservation primates, bat, alligator, elephant, cat, emu, leopard, salmon etc. ...
Gene Regulation - Biomedical Informatics
Gene Regulation - Biomedical Informatics

... 46. Many of the eukaryotic genes contain two or more protein-coding exons and intervening non-coding introns. 47. In prokaryotic cells, translation of an mRNA into protein can begin from the 5’ end of the mRNA even while the 3’ end is still being copied from DNA. 48. In eukaryotic cells, the primary ...
What have we learned from Unicellular Genomes?
What have we learned from Unicellular Genomes?

... remnant internalized alga retaining its small genome needed for plasmodium survival. ...
Prokaryotic genome-size evolution Range of C values in prokaryotes
Prokaryotic genome-size evolution Range of C values in prokaryotes

... The yeast nuclear genome contains about 300 protein-coding genes that function exclusively in the mitochondria. Presumably, some of these genes were once part of the mitochondrial genome which currently contains 28 proteincoding genes. ...
13 Transcription and translation
13 Transcription and translation

... ● Only 20 amino acids found in proteins, depend on combination of bases in codon
 - 4 bases, 3 in codon = 64 possible different combinations for the 20 different amino acids
 - therefore some amino acids have more than one codon ● Start and stop codons initiate or terminate protein synthesis ...
BIOL290
BIOL290

... microRNA, poly(A) tail, intron, exon, promoter, RNA interference, small interfering RNA, small nuclear RNA, microRNA, upstream, downstream, transgene, transgene silencing, spliceosome, ribozyme, hairpin loop, small nuclear ribonucleoproteins Big Concepts/Ideas A. Properties of RNA B. Classes of RNA ...
General Replication Strategies for RNA Viruses
General Replication Strategies for RNA Viruses

... When consisdering all of our DNA, including the genes and many other sequences which do not encode proteins, we are talking about our genome. This name also applies to viruses - although a viral genome has much less DNA (or RNA) than a human genome. A cistron is the smallest unit of DNA that can enc ...
The E. coli genome. - life.illinois.edu.
The E. coli genome. - life.illinois.edu.

... out there, and that some have entirely novel metabolic abilities. They also confirm that there are only the known three domains of life. When the sample is relatively simple, e.g. a few species from a toxic mine sample, entire circular genomes will sometimes assemble. Otherwise they generally obtain ...
The Role of RNA
The Role of RNA

... Eukaryotic Gene Regulation Transcription factors are DNA-binding proteins. They control the expression of genes in eukaryotes by binding DNA sequences in the regulatory regions. Gene promoters have multiple binding sites for transcription factors, each of which can influence transcription. Complex g ...
RNA processing
RNA processing

... transcript by RNA polymerase I from a gene – There are multiple copies of these genes and transcription is almost ...
Intrdouction to Annotation (djs)
Intrdouction to Annotation (djs)

... 1. In any segment of DNA, typically only one frame in one strand is used for a proteincoding gene. That is, each double-stranded segment of DNA is generally part of only one gene. 2. Genes do not often overlap by more than a few bp, although up to about 30 bp is legitimate. 3. The gene density in ph ...
MGY428- Genomes
MGY428- Genomes

... Centromeres mediate interactions between sister chromatids and the kinetochore during replication In budding yeast centromeres are 125 bp in length and contain specific sites for binding kinetochore proteins. In human the centromere is composed of hundreds of thousands of copies of a 171 bp repeat t ...
8.4 Transcription
8.4 Transcription

... • The two processes have different end results. – Replication copies all the DNA; one gene growing RNA strands transcription copies a gene. – Replication makes DNA one copy; transcription can make many copies. ...
FunctionalGenomicsEvolution
FunctionalGenomicsEvolution

... Examples From the Voss Lab ...
Chapter 3
Chapter 3

... Introns can be detected by the presence of additional regions when genes are compared with their RNA products by restriction mapping or electron microscopy. o The ultimate definition, though, is based on comparison of sequences. The positions of introns are usually conserved when homologous genes ar ...
Chap2 DNA RNA and Protein
Chap2 DNA RNA and Protein

... Activators: TF that can bind the promoters or enhancers and increase the efficiency the basal apparatus binds to the promoter. Some activators are ubiquitous but others have a regulatory role and are synthesized/activated at specific time or in specific tissues, to bind the response elements. ...
Stem Cells, Cancer, and Human Health
Stem Cells, Cancer, and Human Health

... produces proteins. C. Translation occurs in the cytoplasm and produces proteins. D. Translation occurs in the nucleus and produces RNA. ...
BIN-2002
BIN-2002

... regulatory elements help to confirm the prediction (in case of bacteria, ribosomal binding site at 5’; terminator sequence at 3’; upstream promoters …); • If these genes contain introns, exons may be identified in two ways – By comparing the gene region with transcript sequences (do not contain intr ...
Repressor protein - Edwin C. Foreman High School
Repressor protein - Edwin C. Foreman High School

... – tightly wrapped around histones • no transcription • genes turned off ...
Regulation of Gene Expression
Regulation of Gene Expression

...  Operator: “on/off” switch, controls if RNA poly can bind or not. NO RNA POLY. BINDING = NO TRANSCTIPTION  Operon: Whole segment of DNA including the promoter, operator, and the genes they control. ...
Genetics
Genetics

...  epistasis (coat color) presence of certain alleles on one locus mask the expression of alleles on another locus and express their own phenotype instead.  pleiotropy (dwarfism, giantism) one allele affects various phenotypes in an organism.  polygenic (skin color) multiple alleles are required fo ...
Abstract
Abstract

... MicroRNAs are an abundant class of 21–22 nt, non-coding RNAs that play a critical role in a wide range of developmental pathways in plants through ARGONAUTE1 (AGO1) post-transcriptional regulation of target mRNAs. Genetic analysis of ago1 mutants with informative defects has provided valuable insigh ...
Section 13.4 Gene Regulation and Expression
Section 13.4 Gene Regulation and Expression

... Clusters of Hox genes exist in the DNA of other animals, including the mouse shown, and humans. These genes are arranged in the same way—from head to tail. The colored areas on the mouse show the approximate body areas affected by genes of the corresponding colors. ...
Non-coding RNA for ZM401, a Pollen
Non-coding RNA for ZM401, a Pollen

... L. was constructed. One cDNA fragment, designated ZM401 (Z. mays), was obtained from maize mat ure pollen cDNA library by differential scree ning and cold-plaque screening method. It was specifically or preferentially expressed in mature pollen. According to the ZM401 cDNA fragment sequence, full le ...
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Short interspersed nuclear elements (SINEs)

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