Expression of SpC3, the sea urchin complement component, in
... These problems were addressed by modifying several of the protocols that had been used previously for the current study. First, by miniaturizing the assays to use as little as 300 l of CF, single animals could be sampled repeatedly and responses to immune challenge or injury could be followed over ...
... These problems were addressed by modifying several of the protocols that had been used previously for the current study. First, by miniaturizing the assays to use as little as 300 l of CF, single animals could be sampled repeatedly and responses to immune challenge or injury could be followed over ...
Development of Zinc Finger Domains for Recognition of the 5
... gests that DNA binding is predominantly achieved by the interaction of amino acid residues of the ␣-helix in positions ⫺1, 3, and 6 with the 3⬘, middle, and 5⬘ nucleotides of a 3-bp DNA subsite, respectively (11, 12). Positions 1, 2, and 5 of the ␣-helix make direct or water-mediated contacts with t ...
... gests that DNA binding is predominantly achieved by the interaction of amino acid residues of the ␣-helix in positions ⫺1, 3, and 6 with the 3⬘, middle, and 5⬘ nucleotides of a 3-bp DNA subsite, respectively (11, 12). Positions 1, 2, and 5 of the ␣-helix make direct or water-mediated contacts with t ...
Can the Hair Follicle Become a Model for Studying Selected
... and differentiation of antigen-specific Th1 effector cells,85 whereas CD8⫹ ACAID-Tregs inhibit the local function of effector T cells (Th1 and Th2).15,93,94 Two other elements, are also important in the induction of ACAID: the thymus and the sympathetic nervous system.59 Although the thymus is an im ...
... and differentiation of antigen-specific Th1 effector cells,85 whereas CD8⫹ ACAID-Tregs inhibit the local function of effector T cells (Th1 and Th2).15,93,94 Two other elements, are also important in the induction of ACAID: the thymus and the sympathetic nervous system.59 Although the thymus is an im ...
Rapid and Quantitative Detection of Toxoplasma Gondii by PCR
... gondii (T. gondii). The infection is usually asymptomatic and harmless in immunocompetent patients, but can be life-threatening or responsible for severe sequelae in immunocompromised individuals, such as fetuses, HIV-positive, and transplant patients. In these situations, early treatment significan ...
... gondii (T. gondii). The infection is usually asymptomatic and harmless in immunocompetent patients, but can be life-threatening or responsible for severe sequelae in immunocompromised individuals, such as fetuses, HIV-positive, and transplant patients. In these situations, early treatment significan ...
Radiation Hybrid Mapping: A Somatic Cell Genetic Method for
... pairs of DNA at the 500-kb level of resolution. We now describe the use of RH mapping, in conjunction with PFGE, to construct a highresolution map of the proximal 20 Mb of the long arm of human chromosome 21. Theory and practice o f radiation hybrid mapping. In this method, which is based on earlier ...
... pairs of DNA at the 500-kb level of resolution. We now describe the use of RH mapping, in conjunction with PFGE, to construct a highresolution map of the proximal 20 Mb of the long arm of human chromosome 21. Theory and practice o f radiation hybrid mapping. In this method, which is based on earlier ...
Accepted Version - CSIRO Research Publications Repository
... Another mutant phenotype seen in the ddm1 background, change of plant structure (short and compact inflorescence with reduced plant height), is bns (BONSAI), which is unstably inherited in the presence of the DDM1 gene. The BNS gene encodes a protein with similarity to the mammalian cell cycle regul ...
... Another mutant phenotype seen in the ddm1 background, change of plant structure (short and compact inflorescence with reduced plant height), is bns (BONSAI), which is unstably inherited in the presence of the DDM1 gene. The BNS gene encodes a protein with similarity to the mammalian cell cycle regul ...
Figures
... Figure 7. Cerebellar learning and performance deficits co-vary with circuit-specific gene expression patterns. (A) The first four data columns show perturbations in learning (green shading) and performance (yellow shading). The last three columns show combined gene expression (Figure 1) and morpholo ...
... Figure 7. Cerebellar learning and performance deficits co-vary with circuit-specific gene expression patterns. (A) The first four data columns show perturbations in learning (green shading) and performance (yellow shading). The last three columns show combined gene expression (Figure 1) and morpholo ...
... This thesis aimed to investigate the role of alveolar epithelial cells (AEC) on immune responses against mycobacterial infections, specifically, the role of AEC in modulating macrophage functions through the secretion of broad variety of factors. In paper I, we investigated the role of AEC in the de ...
Temporal expression patterns of rainbow trout immune
... eliciting an innate immune response that is more effective than TL. This initial time period corresponds with M. cerebralis sporoplasm cells multiplying and migrating from the epidermis to the dermis during the first 2 h of infection and then progressively moving into peripheral nerves [25]. The tren ...
... eliciting an innate immune response that is more effective than TL. This initial time period corresponds with M. cerebralis sporoplasm cells multiplying and migrating from the epidermis to the dermis during the first 2 h of infection and then progressively moving into peripheral nerves [25]. The tren ...
Functional Comparison of Innate Immune Signaling Pathways in
... Due to our natural focus on humans, we know of a large number of diseases or medical conditions that affect humans more severely than non-human primates. Examples include progression to AIDS following infection with HIV, progression to malaria following infection with Plasmodium falciparum, Alzheime ...
... Due to our natural focus on humans, we know of a large number of diseases or medical conditions that affect humans more severely than non-human primates. Examples include progression to AIDS following infection with HIV, progression to malaria following infection with Plasmodium falciparum, Alzheime ...
Card9 Mediates Intestinal Epithelial Cell Restitution, T
... microbe-elicited reactive oxygen species production.11 Furthermore, p38 and JNK activation, as well as cytokine production after infection with RNA viruses, relies on CARD9 through Mda5, RIG-I, and MAVS.12 CARD9 is therefore a key adapter protein for innate immunity against a range of microorganisms ...
... microbe-elicited reactive oxygen species production.11 Furthermore, p38 and JNK activation, as well as cytokine production after infection with RNA viruses, relies on CARD9 through Mda5, RIG-I, and MAVS.12 CARD9 is therefore a key adapter protein for innate immunity against a range of microorganisms ...
DNA How the Molecule of Heredity Carries, Replicates, and
... •Proteins read the DNA sequence of nucleotides as the DNA helix unwinds. Proteins can either bind to a DNA sequence, or initiate the copying of it. •Human genome is believed to be 250 million nucleotides long. Four possible nucleotides. Thus 4250,000,000 possible sequences in the human genome. •An a ...
... •Proteins read the DNA sequence of nucleotides as the DNA helix unwinds. Proteins can either bind to a DNA sequence, or initiate the copying of it. •Human genome is believed to be 250 million nucleotides long. Four possible nucleotides. Thus 4250,000,000 possible sequences in the human genome. •An a ...
CENTERS FOR DISEASE CONTROL AND PREVENTION
... • Apnea following intramuscular vaccination has been observed in some infants born prematurely. Vaccination of premature infants should be based on the infant’s medical status, and the potential benefits and risks • In adults, the commonly reported solicited adverse reactions were pain, redness, a ...
... • Apnea following intramuscular vaccination has been observed in some infants born prematurely. Vaccination of premature infants should be based on the infant’s medical status, and the potential benefits and risks • In adults, the commonly reported solicited adverse reactions were pain, redness, a ...
p53 AND CANCER - Journal of Chemical and Pharmaceutical
... biological processes, many of which encipher proteins that control the cell cycle or induce apoptosis. Because of its critical impact on cell predestination, cellular p53 activity must exactly be controlled. It was first thought to be an ontogeny, but 10 years later researchers Bert Vogelstein and R ...
... biological processes, many of which encipher proteins that control the cell cycle or induce apoptosis. Because of its critical impact on cell predestination, cellular p53 activity must exactly be controlled. It was first thought to be an ontogeny, but 10 years later researchers Bert Vogelstein and R ...
Downloaded - The Journal of Immunology
... To probe for B. burgdorferi-specific Ab-producing cells, 96-well plates (Multiscreen HA filtration; Millipore) were coated overnight with four immune prevalent recombinant B. burgdorferi proteins all generated based on the N40 sequence, 1 mg/ml DbpA and 2 mg/ml each for outer surface protein C (OspC ...
... To probe for B. burgdorferi-specific Ab-producing cells, 96-well plates (Multiscreen HA filtration; Millipore) were coated overnight with four immune prevalent recombinant B. burgdorferi proteins all generated based on the N40 sequence, 1 mg/ml DbpA and 2 mg/ml each for outer surface protein C (OspC ...
Characterization of Chicken MMP13 Expression and Genetic Effect
... follicles of sexually immature chicken ovaries, in the theca cell layers of all sized follicles of sexually mature chicken ovaries. Furthermore, we identified a positive element (positions –1863 to –1036) controlling chicken MMP13 transcription, and, in this region, six single nucleotide polymorphism ...
... follicles of sexually immature chicken ovaries, in the theca cell layers of all sized follicles of sexually mature chicken ovaries. Furthermore, we identified a positive element (positions –1863 to –1036) controlling chicken MMP13 transcription, and, in this region, six single nucleotide polymorphism ...
Early life cytokines, viral infections and IgE
... cytokines, which has led to the conclusion that not only Th cells, but also for example CTL cells, dendritic cells (DC) and natural killer (NK) cells, can be divided into type 1 and type 2, depending on their cytokine production [20-22]. It is also clear that there are definitely other Th-cell linea ...
... cytokines, which has led to the conclusion that not only Th cells, but also for example CTL cells, dendritic cells (DC) and natural killer (NK) cells, can be divided into type 1 and type 2, depending on their cytokine production [20-22]. It is also clear that there are definitely other Th-cell linea ...
Cytokine function of heat shock proteins - AJP
... The reported HSP cytokine effects are similar to those of LPS and bacterial lipoprotein. Because the recombinant bacterial and human HSPs are produced by Escherichia coli expressing HSP cDNAs, the final preparations may be contaminated with bacterial products. Likewise, HSP preparations isolated fro ...
... The reported HSP cytokine effects are similar to those of LPS and bacterial lipoprotein. Because the recombinant bacterial and human HSPs are produced by Escherichia coli expressing HSP cDNAs, the final preparations may be contaminated with bacterial products. Likewise, HSP preparations isolated fro ...
Ability of basophils to induce naive CD4 + T cells to develop into
... OVA-pulsed basophils induce TH2 cells in vivo Basophils + DNP-OVA + IgE anti DNP mice + challenge with OVA CD4+ T cells + OVA-pulsed DT–spleen cells ...
... OVA-pulsed basophils induce TH2 cells in vivo Basophils + DNP-OVA + IgE anti DNP mice + challenge with OVA CD4+ T cells + OVA-pulsed DT–spleen cells ...
Epstein-Barr Virus: An Important Vaccine Target for Cancer Prevention
... gp350 vaccine trial in healthy humans, we recommend that a phase 3 trial of an EBV vaccine be designed and conducted with the goal of licensure for the prevention of IM; we also recommend that blood EBV DNA concentrations be measured in placebo and EBV-vaccinated trial participants who subsequently ...
... gp350 vaccine trial in healthy humans, we recommend that a phase 3 trial of an EBV vaccine be designed and conducted with the goal of licensure for the prevention of IM; we also recommend that blood EBV DNA concentrations be measured in placebo and EBV-vaccinated trial participants who subsequently ...
assembly biosciences, inc. form 8-k
... Efficacy: ABI - M101 oral capsules incorporate select strains of vegetative bacteria to achieve similar efficacy and safety profile as FMT in the treatment of rCDI • We believe that a therapy including both spore and non - spore forming vegetative bacteria, delivered specifically to the lower GI tra ...
... Efficacy: ABI - M101 oral capsules incorporate select strains of vegetative bacteria to achieve similar efficacy and safety profile as FMT in the treatment of rCDI • We believe that a therapy including both spore and non - spore forming vegetative bacteria, delivered specifically to the lower GI tra ...
DNA vaccination
DNA vaccination is a technique for protecting an animal against disease by injecting it with genetically engineered DNA so cells directly produce an antigen, resulting in a protective immunological response. Several DNA vaccines have been released for veterinary use, and there has been promising research using the vaccines for viral, bacterial and parasitic diseases, as well as to several tumour types. Although only one DNA vaccine has been approved for human use, DNA vaccines may have a number of potential advantages over conventional vaccines, including the ability to induce a wider range of immune response types.