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Profile Documents Logout
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Document
Document

... • Affinity maturation = affinity of antibodies for protein antigens increases with prolonged or repeated exposure to the antigens (B cells migrate into follicles and form germinal centers → proliferate rapidly and their Ig V genes undergo extensive somatic mutations; at the same time, the antigen co ...
Edward Jenner, 1796 - University of California, Los Angeles
Edward Jenner, 1796 - University of California, Los Angeles

... at all loci except for one thought to be important in transplantation (Snell, Amos 1950s) • Major histocompatibility complex MHC (H-2 in mice HLA in humans a locus of tightly linked genes (Benacerraf; Dausset;Snell Nobel Prize ...
Questions
Questions

... underlying genetic cause or influence. If the function of the gene product is compromised in these individuals, a correlation between the gene and disease expression is supported. Indeed, it was found that individuals possessing a defective complement component are highly susceptible to SLE. It is c ...
DNA
DNA

... If replication was dispersive, only one band would be expected because all the DNA would be the same weight. What appeared though was two bands. One was radioactive and the other was not. This eliminated the dispersive theory. DNA replication is semiconservative theory. ...
AS 90715 version 2 Describe the role of DNA in relation to gene
AS 90715 version 2 Describe the role of DNA in relation to gene

... modification of phenotype by environment, eg determination of sex in crocodile hatchlings by temperature. ‰ mutations: selected from o gene mutations o chromosomal mutations ‰ the control of metabolic pathways by gene expression: selected from o simple feedback control in prokaryotes (repressors, in ...
Immunity
Immunity

... The Clonal Selection Theory of Antibody Formation: • Great number of antigens can be fought (mouse can form antibodies against 10 million different antigens!). • Each person has a large # of B lymphocytes, each only able to synthesize one type of antibody (on its surface). • When an antigen is intr ...
Using restriction enzymes, foreign genes can be added to an
Using restriction enzymes, foreign genes can be added to an

DNA/RNA
DNA/RNA

... • Types of mutations – Frame Shift Mutations: the number of nucleotides inserted or deleted is not a multiple of three, so that every codon beyond the point of insertion or deletion is read incorrectly during ...
Protein Synthesis SG
Protein Synthesis SG

... 22. In what ways are mutations helpful, harmful or have no effect? Give specific examples. 23. In what way does protein synthesis ensure that the protein is correctly made? 24. What forms can a viral genome take? 25. Describe the lytic and lysogenic infection cycles. Compare & contrast how they allo ...
Genetics Biotech PREAP 2014
Genetics Biotech PREAP 2014

... • Produce a host of important substances such as insulin, growth hormone, and clotting factor which are used to treat serious human diseases and conditions. • Oil eating bacteria help clean up oil spills • Bacteria transformed with the genes for human proteins now produce these important compounds c ...
The Immune Response - Point Pleasant Beach School District
The Immune Response - Point Pleasant Beach School District

... The Clonal Selection Theory of Antibody Formation: • Great number of antigens can be fought (mouse can form antibodies against 10 million different antigens!). • Each person has a large # of B lymphocytes, each only able to synthesize one type of antibody (on its surface). • When an antigen is intr ...
Pioneer Molecular Biologist - St. Helens School District
Pioneer Molecular Biologist - St. Helens School District

... responsible for much of the research and discovery work that led to the understanding of the structure of deoxyribonucleic acid, DNA. The story of DNA is a tale of competition and intrigue, told one way in James Watson's book The Double Helix, and quite another in Anne Sayre's study, Rosalind Frankl ...
Semiconservative
Semiconservative

... Speeding up the protein assembly line in bacteria ...
ACTIVE READING WORKSHEETS
ACTIVE READING WORKSHEETS

... Many viral diseases, such as influenza, smallpox, and polio, cannot be treated effectively by existing drugs. Instead, many viral diseases are combated by prevention, using vaccines. A vaccine is a substance that contains a harmless version of a virus or a bacterium. Traditionally, vaccines have bee ...
Genetic Engineering
Genetic Engineering

... • Produce a host of important substances such as insulin, growth hormone, and clotting factor which are used to treat serious human diseases and conditions. • Oil eating bacteria help clean up oil spills • Bacteria transformed with the genes for human proteins now produce these important compounds c ...
Slideshow
Slideshow

... Symbols are used to indicate gender and presence of a trait ...
Rate of evolution
Rate of evolution

... Sharing of beneficial DNA sequences • The sharing of beneficial DNA sequences between different lineages through sexual reproduction creates genetic variation. This increase in variation in a population allows them to adapt to ever changing environmental conditions. It gives sexually reproducing or ...
Unt 12 Immune System Disorders Powerpoint
Unt 12 Immune System Disorders Powerpoint

... ...
DNA
DNA

... • 7.5-25 x 103 base pairs • 100-1000 copies depending on whether the cell is actively dividing (more when dividing). • ~100 genes Mitochondria have their own DNA (called the Mitochondrial genome) • ~1.7 x 104 base pairs • several copies • ~40 genes ...
Meiosis
Meiosis

... for the proteins required by that cell at that time. The remainder of the DNA is not expressed Example: ...
Ch 12 2nd and 3rd Lines of Defense
Ch 12 2nd and 3rd Lines of Defense

... - Pollen grains - Microorganisms ...
Timeline
Timeline

... sequence human genome began 2000 - In US first ‘saviour sibling’ produced using PGD ...
Chp 11.2: Nucleic Acid structure and sequence
Chp 11.2: Nucleic Acid structure and sequence

... These errors in DNA can be caused by long-term chemical or radiation exposure. These errors in Gene copies can either replace the correct, normal Genetic Codes with a different Code, or leave out a piece of a trait’s code completely. ...
PowerPoint 簡報
PowerPoint 簡報

... The transcription apparatus of Prokaryotes Operons: Major shift in Prokaryotic transcription ...
Exploring Mutant Organisms Teacher Extended Background
Exploring Mutant Organisms Teacher Extended Background

... how genes influence individual cells within a living organism. C. elegans was the first multicellular eukaryote to have its genome sequenced. Functional genetic studies typically rely on mutating a particular gene, then looking for physical or behavioral changes in the organism. Obviously, such expe ...
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DNA vaccination



DNA vaccination is a technique for protecting an animal against disease by injecting it with genetically engineered DNA so cells directly produce an antigen, resulting in a protective immunological response. Several DNA vaccines have been released for veterinary use, and there has been promising research using the vaccines for viral, bacterial and parasitic diseases, as well as to several tumour types. Although only one DNA vaccine has been approved for human use, DNA vaccines may have a number of potential advantages over conventional vaccines, including the ability to induce a wider range of immune response types.
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