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Powerful Vaccine Discovery
Powerful Vaccine Discovery

... reach large populations and prevent endemic disease. Using novel technologies such as flagellin-based fusion proteins, scientists at Wake Forest Baptist Medical Center and Wake Forest University are developing highly potent, cost-effective vaccines that provide protective immunity against a range of ...
(DTH) mouse model for atopic dermatitis
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... etiology of widely prevalent atopic dermatitis (up to 15%) is unknown, but a genetically deficient skin epithelial barrier is a major factor. In allergic contact dermatitis (prevalence 7-10%), eliciting factors include local exposure of the skin to environmental agents such as natural rubber, metals ...
Promoter-trapping in Saccharomyces cerevisiae
Promoter-trapping in Saccharomyces cerevisiae

... 2001, the site of insertion has been characterised in more than 22 000 insertion clones, less than two-thirds of the about 6200 yeast genes are represented in this collection (7). In addition to gene-size dependent biases in targeting ef®ciency, nonrandom insertion of Tn3-derived transposons (8) and ...
principles of genetics
principles of genetics

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PDF - Sci Forschen
PDF - Sci Forschen

... genotyped O/O in the normal and A/O in the tumor. This result is not in agreement with David L’s study which has shown that all cases expressing A antigen are genotyped O/O with common deletion 261delG [25]. In order to investigate possible mutations responsible for A antigen expression and to answe ...
BRED: Bacteriophage Recombineering with
BRED: Bacteriophage Recombineering with

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Long Noncoding RNAs May Alter Chromosome`s 3D

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Institute for Microbiology, Medical Faculty of Masaryk
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UNIT SIX: MOLECULAR GENETICS AND BIOTECHNOLOGY

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genetics chapter - UBC Let`s Talk Science
genetics chapter - UBC Let`s Talk Science

... A plasmid is a type of vector (Figure 13). A plasmid is a circular piece of DNA. Bacteria often have plasmids present in their cells and use them in the case of “emergencies”. For example, plasmids commonly carry genes for antibiotic resistance. These are genes that wouldn’t be required under normal ...
Slide 1 - Schools
Slide 1 - Schools

... vector – Use the virus to deliver the gene to an affected cell type from the patient, such as a bone marrow cell – Viral DNA and the functional allele will insert into the patient’s chromosome – Return the cells to the patient for growth and division Copyright © 2009 Pearson Education, Inc. ...
Current Research of Extracorporeal Photopheresis and Future
Current Research of Extracorporeal Photopheresis and Future

... complex (MHC). The MHC is a set of molecules on the surface of the cells which facilitates the interactions of leukocytes (WBCs). CD4+ and CD8+ T-cells, and cytokines are the main disease facilitators. In every individual, the MHC takes on its own unique genetic coding. One of the primary functions ...
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Cloning, expression, and characterization of Fe

... listed among the top category of key, protected, wild plants (Yu, 1999). According to Ching’s system, I. sinensis belongs to Isöephytina (Ching, 1978). However, based on molecular data, some scholars suggest that I. sinensis should be classified into Lycophytina (Liu et al., 2008). Under normal grow ...
DNA-Directed Antibody Immobilization for
DNA-Directed Antibody Immobilization for

... immobilization. One such technique, DNA-directed immobilization (DDI), combines the robustness of DNA microarrays with the diagnostic utility of proteins through the use of protein−DNA conjugates to functionalize a DNA surface for subsequent antigen capture.10−19 In DDI, each antibody is encoded by ...
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DNA vaccination



DNA vaccination is a technique for protecting an animal against disease by injecting it with genetically engineered DNA so cells directly produce an antigen, resulting in a protective immunological response. Several DNA vaccines have been released for veterinary use, and there has been promising research using the vaccines for viral, bacterial and parasitic diseases, as well as to several tumour types. Although only one DNA vaccine has been approved for human use, DNA vaccines may have a number of potential advantages over conventional vaccines, including the ability to induce a wider range of immune response types.
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