Ch 1 section headings and legends
... bone marrow and the thymus, where B cells and T cells, respectively, undergo most or all of their development. (b) Secondary lymphoid tissues or organs are sites where adaptive responses are induced and regulated. The main tissues are lymph nodes, the spleen and specialized mucosal-associated lympho ...
... bone marrow and the thymus, where B cells and T cells, respectively, undergo most or all of their development. (b) Secondary lymphoid tissues or organs are sites where adaptive responses are induced and regulated. The main tissues are lymph nodes, the spleen and specialized mucosal-associated lympho ...
How mast cells make decisions
... that the powerful and sustained pathological responses associated with FcεRI-mediated MC activation can be attributable to the larger-sized exteriorized granules, which persist for longer periods and slowly release their cargo of inflammatory mediators. Interestingly, not all exteriorized MC granule ...
... that the powerful and sustained pathological responses associated with FcεRI-mediated MC activation can be attributable to the larger-sized exteriorized granules, which persist for longer periods and slowly release their cargo of inflammatory mediators. Interestingly, not all exteriorized MC granule ...
iGenetics: A Molecular Approach, 3e (Russell/Bose)
... Comparison of the genomes of different dog breeds may therefore shed light on which genetic elements are responsible for the radically different developmental pathways of different dog breeds–a process that may represent a microcosm of species-level differentiation over evolutionary time. Skill: Con ...
... Comparison of the genomes of different dog breeds may therefore shed light on which genetic elements are responsible for the radically different developmental pathways of different dog breeds–a process that may represent a microcosm of species-level differentiation over evolutionary time. Skill: Con ...
New genes with old modus operandi
... The search for partition functions The earliest efforts to identify partition genes in bacteria involved screening for conditional lethal mutations that cause defects in the segregation of bacterial nucleoids, the folded nucleoprotein structure of the E. coli genome. A large number of segregationdef ...
... The search for partition functions The earliest efforts to identify partition genes in bacteria involved screening for conditional lethal mutations that cause defects in the segregation of bacterial nucleoids, the folded nucleoprotein structure of the E. coli genome. A large number of segregationdef ...
Molecular Biology of the Cell
... (A) The tethering of a region of chromatin to nuclear pore complex. (B) The tight binding of barrier proteins to a group of nucleosomes. (C) By recruiting a histone modifying enzymes, barriers can erase the histone marks that are required for heterochromatin to spread. For example, HS4 barrier DNA s ...
... (A) The tethering of a region of chromatin to nuclear pore complex. (B) The tight binding of barrier proteins to a group of nucleosomes. (C) By recruiting a histone modifying enzymes, barriers can erase the histone marks that are required for heterochromatin to spread. For example, HS4 barrier DNA s ...
Oxidative stress as an initiator of cytokine release and cell... J.D. Crapo Airway redox balance in health and disease
... and detoxify inhaled antigens and particles. It must both control and express inflammatory pathways in ways that preserve the primary functions of the respiratory system while protecting it from invasion by foreign infective agents or antigens. Inhaled air, even under relatively pristine conditions, ...
... and detoxify inhaled antigens and particles. It must both control and express inflammatory pathways in ways that preserve the primary functions of the respiratory system while protecting it from invasion by foreign infective agents or antigens. Inhaled air, even under relatively pristine conditions, ...
We present here a collection of DNA sequence
... increases the range of tasks the personal computer can perform. Two years ago IBM, the world's largest computer manufacturer, had just introduced its version of the personal computer, the IBM PC. Although not the first microcomputer on the market, the IBM PC is rapidly becoming an industry standard ...
... increases the range of tasks the personal computer can perform. Two years ago IBM, the world's largest computer manufacturer, had just introduced its version of the personal computer, the IBM PC. Although not the first microcomputer on the market, the IBM PC is rapidly becoming an industry standard ...
Chapter 8 - Dr. Jennifer Capers
... Antibodies can recognize antigen alone T-cell receptors can only recognize antigen that has been processed and presented by Major Histocompatibility Complex (MHC) ...
... Antibodies can recognize antigen alone T-cell receptors can only recognize antigen that has been processed and presented by Major Histocompatibility Complex (MHC) ...
ON VACCINES AND IMMUNISATION
... Then the viral preparation is formulated by mixing it with the constituents that allow each dose to be safely delivered in the right concentration. This is the point where the product may also be combined with other antigens (e.g. measles–mumps-rubella vaccine). The formulated product is filled in ...
... Then the viral preparation is formulated by mixing it with the constituents that allow each dose to be safely delivered in the right concentration. This is the point where the product may also be combined with other antigens (e.g. measles–mumps-rubella vaccine). The formulated product is filled in ...
DNA Structure Changes Coupled to Protein Binding
... The anomalous migration of naturally curved DNA during polyacrylamide gel electrophoresis prompted the development of a method based on the gel mobility of synthetic DNA sequences ligated to form multimer repeats (Hagerman, 1990). The idea behind this approach was that local structural variations in ...
... The anomalous migration of naturally curved DNA during polyacrylamide gel electrophoresis prompted the development of a method based on the gel mobility of synthetic DNA sequences ligated to form multimer repeats (Hagerman, 1990). The idea behind this approach was that local structural variations in ...
introducing single molecule real-time (smrt
... HLA typing plays a major role in the selection of haematopoietic stem cell donors and there is published evidence that higher resolution HLA matching is associated with increased overall survival. Presently, many high-throughput molecular HLA typing approaches like PCR-SSOP or SBT lead to ambiguous ...
... HLA typing plays a major role in the selection of haematopoietic stem cell donors and there is published evidence that higher resolution HLA matching is associated with increased overall survival. Presently, many high-throughput molecular HLA typing approaches like PCR-SSOP or SBT lead to ambiguous ...
1 Introduction
... 1.4 Human topoisomerase II Human DNA topoisomerase IIα from Hela cells was the first isoform to be purified and characterized (Miller et al, 1981). Later on, another isoform was identified from murine P388 cells, and was designated topoisomerase IIβ (Drake et al, 1987). DNA topoisomerase IIα is a 1 ...
... 1.4 Human topoisomerase II Human DNA topoisomerase IIα from Hela cells was the first isoform to be purified and characterized (Miller et al, 1981). Later on, another isoform was identified from murine P388 cells, and was designated topoisomerase IIβ (Drake et al, 1987). DNA topoisomerase IIα is a 1 ...
Polyclonal antibodies
... formation of a lattice and precipitation of immune complexes. Antibody and antigen must be multivalent. Occurs most efficiently when antigen and antibody are at similar concentration. ...
... formation of a lattice and precipitation of immune complexes. Antibody and antigen must be multivalent. Occurs most efficiently when antigen and antibody are at similar concentration. ...
S. mansoni - York College of Pennsylvania
... Schistosoma mansoni before or after BCG vaccination, and subsequently challenged with Mycobacterium tuberculosis. If clinical assessments, cellular proliferation analyses, cytokine assays, bacterial counts, and pathologic examinations indicate that helminthic infection reduces efficacy, phase two wi ...
... Schistosoma mansoni before or after BCG vaccination, and subsequently challenged with Mycobacterium tuberculosis. If clinical assessments, cellular proliferation analyses, cytokine assays, bacterial counts, and pathologic examinations indicate that helminthic infection reduces efficacy, phase two wi ...
Chapter_22_Lymphatic_System
... e.g. viruses, parasites, fungi and cancer cells and tissue transplants. Antigens bind to a specific T-cell receptor --> Tcell becomes activated and differentiates into Killer cell and directly attacks the infected cell causing its lysis. – Humoral or antibody mediated response: In this response anti ...
... e.g. viruses, parasites, fungi and cancer cells and tissue transplants. Antigens bind to a specific T-cell receptor --> Tcell becomes activated and differentiates into Killer cell and directly attacks the infected cell causing its lysis. – Humoral or antibody mediated response: In this response anti ...
Predominant cellular immune response to the cartilage
... caused or triggered w5, 18x by an antibacterial immune response anduor perpetuated by an immune response directed against an unknown self-antigen. The fact that no bacterial DNA could be detected in biopsies from sacroiliac joints by the polymerase chain reaction technique (PCR) w19x, and that in sp ...
... caused or triggered w5, 18x by an antibacterial immune response anduor perpetuated by an immune response directed against an unknown self-antigen. The fact that no bacterial DNA could be detected in biopsies from sacroiliac joints by the polymerase chain reaction technique (PCR) w19x, and that in sp ...
How Genes and Genomes Evolve
... among closely related species • Should be conserved because they are responsible for essential cell functions • Co-evolution between protein and protein target • Suggests that the DNA sequence itself may not be that important a determinant of centromere structure & function ...
... among closely related species • Should be conserved because they are responsible for essential cell functions • Co-evolution between protein and protein target • Suggests that the DNA sequence itself may not be that important a determinant of centromere structure & function ...
070600 The Immune System
... gram-negative bacteria, and teichoic acids, which are present on gram-positive bacteria.9 Activation causes dendritic cells to up-regulate the expression of B7 costimulatory molecules (also known as CD80 and CD86) on their surface. Costimulatory molecules are molecules that provide the signals neces ...
... gram-negative bacteria, and teichoic acids, which are present on gram-positive bacteria.9 Activation causes dendritic cells to up-regulate the expression of B7 costimulatory molecules (also known as CD80 and CD86) on their surface. Costimulatory molecules are molecules that provide the signals neces ...
Expressway Plus - Thermo Fisher Scientific
... High-performance protein expression Traditional protein expression systems involve expressing recombinant proteins in intact eukaryotic or prokaryotic cells. Although effective, these methods can be both time-consuming and technically challenging. The Expressway™ Plus Expression System eliminates t ...
... High-performance protein expression Traditional protein expression systems involve expressing recombinant proteins in intact eukaryotic or prokaryotic cells. Although effective, these methods can be both time-consuming and technically challenging. The Expressway™ Plus Expression System eliminates t ...
Abeloff`s Clinical Oncology Update
... mechanisms of innate effector cells. Whereas tumorIn contrast to the rapid responses achieved in the innate specific antibodies have been generated (e.g., trastuzumab immune response, which is believed to be evolutionariand rituximab), such antibodies are predominantly used to ly older, the adaptive ...
... mechanisms of innate effector cells. Whereas tumorIn contrast to the rapid responses achieved in the innate specific antibodies have been generated (e.g., trastuzumab immune response, which is believed to be evolutionariand rituximab), such antibodies are predominantly used to ly older, the adaptive ...
Leukaemia Section t(10;11)(q22;q23) KMT2A/TET1 Atlas of Genetics and Cytogenetics in Oncology and Haematology
... of ESCs. TET1 interacts physically with NANOG, synergistically enhancing the efficiency of NANOG in somatic cell reprogramming. NANOG/TET1 cooccupy genomic loci of genes associated with both maintenance of pluripotency and lineage commitment in embryonic stem cells, and may deposit 5hmC to target ge ...
... of ESCs. TET1 interacts physically with NANOG, synergistically enhancing the efficiency of NANOG in somatic cell reprogramming. NANOG/TET1 cooccupy genomic loci of genes associated with both maintenance of pluripotency and lineage commitment in embryonic stem cells, and may deposit 5hmC to target ge ...
DNA vaccination
DNA vaccination is a technique for protecting an animal against disease by injecting it with genetically engineered DNA so cells directly produce an antigen, resulting in a protective immunological response. Several DNA vaccines have been released for veterinary use, and there has been promising research using the vaccines for viral, bacterial and parasitic diseases, as well as to several tumour types. Although only one DNA vaccine has been approved for human use, DNA vaccines may have a number of potential advantages over conventional vaccines, including the ability to induce a wider range of immune response types.