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The Roles of the Quorum-Sensing System in the Release of
The Roles of the Quorum-Sensing System in the Release of

... reaction for PAO-JP2 when it was exposed to a mAb against P. aeruginosa serotype O5 (data not shown). However, a reaction to the mAb was detected in the PAO-JP2 samples cultured with C12-HSL. This band was not detected when C4HSL was used instead of C12-HSL. These results indicate that when the las ...
The Chicken Genetic Map and Beyond Hans H. Cheng USDA
The Chicken Genetic Map and Beyond Hans H. Cheng USDA

... number of loci or progeny to be typed. Finally, the markers should be in a form that can be easily disseminated among laboratories. The _ew molecular genetic map will rely on DNA-based markers which will increase the usefulness of the map. DNA-based markers can satisfy all the requirements of an id ...


... transformed Agrobacterium cells. Its T-DNA is now specifically modified and acts as a gene vector. Vectors are tools used in molecular biology for transferring foreign genetic information and the aim of this vector is to express the gene of interest in the transformed organism, in this case Arabidop ...
Gene Section FANCF  (Fanconi  anemia,  complementation  group F)
Gene Section FANCF (Fanconi anemia, complementation group F)

... group F; it represents about 2-3% of FA cases. Disease Fanconi anaemia is a chromosome instability syndrome/cancer prone disease (at risk of leukaemia and squamous cell carcinoma). Prognosis Fanconi anaemia's prognosis is poor; mean survival is 20 years: patients die of bone marrow failure (infectio ...
Gamma globulins
Gamma globulins

... Antigen • A substance that initiates and mediates the formation of the corresponding immune body; antibody. • Antigens can also react with formed antibodies. • Antigen-antibody reactions serve as host defenses against microorganisms and other foreign bodies • It used in laboratory tests for detecti ...
supporting information
supporting information

... with binding scores above average were modeled in analogy to MHC class II-bound peptides in known structures (DR, I-Ak), and energy-minimized. Of these, sequences that were seen to fit into the MHC binding site were taken as representing possible HLA-binding epitopes. We have used this system succe ...
Major Contributing Factor in Increased Antibiotic Resistance
Major Contributing Factor in Increased Antibiotic Resistance

... such as beta-lactam penicillins (2). However, even antibiotics targeted at cellular functions such as protein and DNA synthesis, which should affect slow-growing bacteria exhibit reduced efficacy against biofilms. Bacterial cells in a biofilm can also mount a stress response in the presence of an an ...
sheet_4
sheet_4

... microfilaments cytoskeleton, and inside there is a dense tubular system, both preserve the shape of the platelets. v Function of the platelets: haemostasis. How does it help in haemostasis? Does it help stop bleeding from a large artery? No, but when there is a bleeding from a ruptured small artery ...
Powerpoint summary
Powerpoint summary

... Biotech Time Line Humans domesticate crops and livestock ...
Modeling and Simulation of the Innate Immune System
Modeling and Simulation of the Innate Immune System

Viruses
Viruses

... • Viruses identify their hosts by a lock and key mechanism. However some viruses have wider range than others such as swine flue virus can infect both humans and hogs while rabies virus can infect a number of mammalian species including raccoons, skunks, dogs and humans. • Viruses of eukaryotes are ...
S-Phase Checkpoint Genes Safeguard High
S-Phase Checkpoint Genes Safeguard High

... phosphorylation requires Nbs1 (Kim et al., 2002b), a constituent of MRN (Mre11, Rad50, and Nbs1). MRN is a wellstudied protein complex required for double-strand break repair and is conserved across Eukaryotae (reviewed in D’Amours and Jackson, 2002; Wyman and Kanaar, 2002; Bradbury and Jackson, 200 ...
LiMA overview
LiMA overview

... portion of the extracted material which may or may not contain enough target to be detected (a single organism and its genome can only be detected if it ends up in the PCR). • LiMA can be used as a marker of viable bacteria – the ligase disappears with loss of viability. Direct PCR will detect the g ...
Evasion of Host Immune Surveillance by Hepatitis C Virus: Potential
Evasion of Host Immune Surveillance by Hepatitis C Virus: Potential

... RNA polymerase lacking the proof-reading capability of a 3’–5’ exconuclease activity15, 20. The rate of nucleotide misincorporation in the HCV genome has been estimated at up to 104 base substitutions per genome during one year of infection33. This antigenic variation leads to the presence of multip ...
General_Medicine_-_Test_questions_2016
General_Medicine_-_Test_questions_2016

... 51. Which of the following statements are true for IgG? a. secreted form is a pentamer of the basic H2L2 unit b. binds to Fc receptors on mast cells c. multimeric forms have a J chain d. present on the surface of mature, unprimed B cells e. the most abundant isotype in human plasma f. major antibody ...
as a PDF
as a PDF

... • Viruses recognize host cells by a complementary fit between external viral proteins and specific cell surface receptor sites. • Some viruses have broad host ranges which may include several species (e.g. swine flu and rabies). • Some viruses have host ranges so narrow that they can: ⇒ infect only ...
An Overview of Application of Artificial Immune System in Swarm
An Overview of Application of Artificial Immune System in Swarm

... Dendritic cells within an innate immune system are cells which respond to some specific danger signals. The three main types of dendritic cells such as: 1) Immature Dendritic Cells, which collect parts of the antigen and the signals, 2) Semi-mature Dendritic cells, are immature cells which have deci ...
the novozymes prize - Novo Nordisk Fonden
the novozymes prize - Novo Nordisk Fonden

... research that forms the basis of CRISPR-Cas9 technology, which provides revolutionary ability to edit genomes for biotechnological science. Two key advances in the ability to manipulate cellular DNA and genomes have arisen from the study of bacterial antiviral defence systems. The first came with th ...
Immune response to human papillomavirus after
Immune response to human papillomavirus after

... lifelong risk of being infected, the primary goal for an HPV vaccine is to ensure long-term protection. If the immune system fails to clear or control an incident infection with oncogenic HPV, the infection may become persistent. A persistent infection is generally defined as the continued detection ...
research presentation - University of Saskatchewan
research presentation - University of Saskatchewan

... reversible airway obstruction; (b) airway hyperresponsiveness (AHR); and (c) airway inflammation. Despite significant pharmacological advances in asthma therapy, the past two decades have seen an alarming increase in the prevalence of asthma world wide. In the United States alone, asthma affects app ...
An integrated model of the recognition of Candida albicans
An integrated model of the recognition of Candida albicans

... 1. Recognition depend on several PAMPs in the fungal cell wall. 2. Specific intracellular signalling pathways, and distinct consequences for the host immune response. 3. Cell-type-specific response of the various PRRs. ...
Molecular phylogeny, part B
Molecular phylogeny, part B

... Molecular phylogenetics: A set of techniques that enable the evolutionary relationships between DNA sequences to be inferred by making comparisons between those sequences. Multigene family: A group of genes, clustered or dispersed, with related nucleotide sequences. Multiple alignment: An alignment ...
DNA-free CRISPR-Cas9 genome engineering in
DNA-free CRISPR-Cas9 genome engineering in

... The CRISPR-Cas9 system permits researchers to quickly edit genes for functional protein knockout in mammalian, fish and plant genomes, among others, and consequently has dramatically transformed biological research. The CRISPR-Cas9 system requires exogenous Cas9 nuclease to be delivered into the cel ...
A group of interacting yeast DNA replication genes.
A group of interacting yeast DNA replication genes.

... and methods after - 1 . 5 generation times at the nonpermissive temperature. Surprisingly, at 15°C the cells apparently complete D N A replication because every cell apparently contains two genome equivalents of D N A [Fig. 2B), whereas at 12°C the same strain arrested with only about one genome equ ...
C2005/F2401 `07 -- Lecture 19 -- Last Edited
C2005/F2401 `07 -- Lecture 19 -- Last Edited

... 1. Chromosomes. DNA (+ associated proteins) visible in microscope as individual structures called chromosomes. DNA tightly coiled, easy to distribute but not accessible to enzymes of replic. and transc. (condensed > 10,000 X). Individual balls of string (in this state) vs unwound, tangled mess (betw ...
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DNA vaccination



DNA vaccination is a technique for protecting an animal against disease by injecting it with genetically engineered DNA so cells directly produce an antigen, resulting in a protective immunological response. Several DNA vaccines have been released for veterinary use, and there has been promising research using the vaccines for viral, bacterial and parasitic diseases, as well as to several tumour types. Although only one DNA vaccine has been approved for human use, DNA vaccines may have a number of potential advantages over conventional vaccines, including the ability to induce a wider range of immune response types.
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