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Udvardy, A.1,Bosnyák, E.1, Trájer, E.1, Protzner, A.1, Komka, Zs.1
Udvardy, A.1,Bosnyák, E.1, Trájer, E.1, Protzner, A.1, Komka, Zs.1

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... purified from brain of wild-type, Zbtb4+/- and Zbtb4-/- mice. The top band of the PCR is derived from the wild-type allele, whereas the lower band is derived from the targeted allele. C, Primers used in PCR for mRNA expression analysis are indicated on top. The relative expression level of Zbtb4 mRN ...
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Epigenomics

Epigenomics is the study of the complete set of epigenetic modifications on the genetic material of a cell, known as the epigenome. The field is analogous to genomics and proteomics, which are the study of the genome and proteome of a cell (Russell 2010 p. 217 & 230). Epigenetic modifications are reversible modifications on a cell’s DNA or histones that affect gene expression without altering the DNA sequence (Russell 2010 p. 475). Two of the most characterized epigenetic modifications are DNA methylation and histone modification. Epigenetic modifications play an important role in gene expression and regulation, and are involved in numerous cellular processes such as in differentiation/development and tumorigenesis (Russell 2010 p. 597). The study of epigenetics on a global level has been made possible only recently through the adaptation of genomic high-throughput assays (Laird 2010) and.
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