BLAST - Georgia State University
... • Every gene contains a regulatory region (RR) upstream of the transcriptional start site • Located within the RR are the Transcription Factor Binding Sites (TFBS), also known as motifs, specific for a given transcription factor • A TFBS can be located anywhere within the Regulatory Region (RR). • A ...
... • Every gene contains a regulatory region (RR) upstream of the transcriptional start site • Located within the RR are the Transcription Factor Binding Sites (TFBS), also known as motifs, specific for a given transcription factor • A TFBS can be located anywhere within the Regulatory Region (RR). • A ...
NIH Public Access
... Rather, the FIS-PcG complex containing MEA itself seems to keep the silenced paternal MEA repressed [5••,6•,7•]. Disruption of the FIS-PcG complex causes loss of MEA imprinting as silencing of the paternal allele is released [5••,6•,7•]. In addition, MEA is physically associated with the MEA promote ...
... Rather, the FIS-PcG complex containing MEA itself seems to keep the silenced paternal MEA repressed [5••,6•,7•]. Disruption of the FIS-PcG complex causes loss of MEA imprinting as silencing of the paternal allele is released [5••,6•,7•]. In addition, MEA is physically associated with the MEA promote ...
The Homologous Drosophila Transcriptional Adaptors ADA2a and
... yeast (Saccharomyces cerevisiae) on the basis of the finding that mutations affecting them confer resistance to toxicity mediated by high-level expression of the GAL4-VP16 fusion protein (7). Yeast ADA proteins play a role in transcriptional initiation site selection, interact with basal transcripti ...
... yeast (Saccharomyces cerevisiae) on the basis of the finding that mutations affecting them confer resistance to toxicity mediated by high-level expression of the GAL4-VP16 fusion protein (7). Yeast ADA proteins play a role in transcriptional initiation site selection, interact with basal transcripti ...
Critical Periods:
... There are numerous examples of differences between males and females in performance on various tests of learning and memory. – Males are “better” at passive avoidance learning than females (e.g., males learn more quickly to not leave a platform because they will get shocked). – Females are “better” ...
... There are numerous examples of differences between males and females in performance on various tests of learning and memory. – Males are “better” at passive avoidance learning than females (e.g., males learn more quickly to not leave a platform because they will get shocked). – Females are “better” ...
PPT
... • PVTI downstream of MYC & may be a transcriptional target of the MYC protein • Insertion of CHD7 with subsequent amplification results in increased gene copy number & regulatory elements • OVEREXPRESSION ...
... • PVTI downstream of MYC & may be a transcriptional target of the MYC protein • Insertion of CHD7 with subsequent amplification results in increased gene copy number & regulatory elements • OVEREXPRESSION ...
non-associative learning representation in the
... we postulate a novel approach on modeling single neurons and synapses to study the mechanisms underlying learning in the C. elegans nervous system. In this regard, we construct a precise mathematical model of sensory neurons where we include multi-scale details from genes, ion channels and ion pumps ...
... we postulate a novel approach on modeling single neurons and synapses to study the mechanisms underlying learning in the C. elegans nervous system. In this regard, we construct a precise mathematical model of sensory neurons where we include multi-scale details from genes, ion channels and ion pumps ...
Methods S1.
... (1997). Transformation was performed as described (Levy et al., 2005). Three days after transformation, the transformed roots were placed in a cover slip chamber (Nalge Nunc International) followed by flushing the roots with liquid MS medium or MS supplemented with 200 mM NaCl. For GFP-STRS localiza ...
... (1997). Transformation was performed as described (Levy et al., 2005). Three days after transformation, the transformed roots were placed in a cover slip chamber (Nalge Nunc International) followed by flushing the roots with liquid MS medium or MS supplemented with 200 mM NaCl. For GFP-STRS localiza ...
Expression of Xenopus T-box transcription factor, Tbx2 in Xenopus
... suggesting that the expression pattern of Tbx2 is generally conserved during evolution. During chick limb specification it has been suggested that Tbx2 may be a direct, short-range target of sonic hedgehog in the formation of the zone of polarizing activity (Gibson-Brown et al. 1998b). In Drosophila ...
... suggesting that the expression pattern of Tbx2 is generally conserved during evolution. During chick limb specification it has been suggested that Tbx2 may be a direct, short-range target of sonic hedgehog in the formation of the zone of polarizing activity (Gibson-Brown et al. 1998b). In Drosophila ...
Special topics in electrical and systems engineering: Systems Biology
... Transcription network involving two-component systems. Black single-lined arrows and T-formed lines show positive and negative transcription regulation, respectively. Green arrows indicate environmental signal inputs. Double-lined arrows depict the synthesis of the gene products from the two-compone ...
... Transcription network involving two-component systems. Black single-lined arrows and T-formed lines show positive and negative transcription regulation, respectively. Green arrows indicate environmental signal inputs. Double-lined arrows depict the synthesis of the gene products from the two-compone ...
Paper - BioMed Central
... Transcriptional analysis between two wheat Near-isogenic lines contrasting in aluminium Tolerance under aluminium stress. Molecular Genetics and Genomics (2007) 277: ...
... Transcriptional analysis between two wheat Near-isogenic lines contrasting in aluminium Tolerance under aluminium stress. Molecular Genetics and Genomics (2007) 277: ...
Chapter Eleven: Chromosome Structure and Transposable Elements
... chromatin structure? Would you predict that this drug would have any effect on gene expression? Explain your answers. Such a drug would disrupt the ionic interactions between the histone tails and the phosphate backbone of DNA and thereby cause a loosening of the DNA from the nucleosome. The drug ma ...
... chromatin structure? Would you predict that this drug would have any effect on gene expression? Explain your answers. Such a drug would disrupt the ionic interactions between the histone tails and the phosphate backbone of DNA and thereby cause a loosening of the DNA from the nucleosome. The drug ma ...
Document
... lacZ gene even in the absence of lactose (media has no glucose). You think you have a mutation in the lacI repressor, but this turns out not to be the case. Which of the following do you think best explains your mutant? A) B) C) D) ...
... lacZ gene even in the absence of lactose (media has no glucose). You think you have a mutation in the lacI repressor, but this turns out not to be the case. Which of the following do you think best explains your mutant? A) B) C) D) ...
UNIT 9 NOTES Genetics
... The DNA is wrapped around the histone core of eight protein subunits, forming the nucleosome. The nucleosome is clamped by histone H1. About 200 base pairs (bp) of DNA coil around one histone. The coil "untwists" so as to generate one negative superturn per nucleosome. ...
... The DNA is wrapped around the histone core of eight protein subunits, forming the nucleosome. The nucleosome is clamped by histone H1. About 200 base pairs (bp) of DNA coil around one histone. The coil "untwists" so as to generate one negative superturn per nucleosome. ...
Gene regulation and bacteriophage
... The workings of the switch are illustrated in Figure 5. The genetic region shown in Fig. 5A comprises the lambda genome from 37227 to 40203, out of a total of 48502 nucleotides. The critical 102-nucleotide region between the cI and cro genes is shown in Fig. 5B. In the absence of any repressor or Cr ...
... The workings of the switch are illustrated in Figure 5. The genetic region shown in Fig. 5A comprises the lambda genome from 37227 to 40203, out of a total of 48502 nucleotides. The critical 102-nucleotide region between the cI and cro genes is shown in Fig. 5B. In the absence of any repressor or Cr ...
Gene converter - Bioinformatics Platform
... SUMMARY CBS is a very helpful tool when characterizing the binding sites for certain TFs in a regulatory sequence. However, it is not uncommon that other applications deal with a different nomenclature for the genes involved in the study. Thus, it is interesting to use this CBS tool to convert gene ...
... SUMMARY CBS is a very helpful tool when characterizing the binding sites for certain TFs in a regulatory sequence. However, it is not uncommon that other applications deal with a different nomenclature for the genes involved in the study. Thus, it is interesting to use this CBS tool to convert gene ...
Gene Enrichment Analysis
... sets that showed signi cant enrichment. About half the sets were shared between the two studies, and there were several non-identical sets that related to the same processes, such as up-regulation by telomerase, and two dierent insulin-related sets. GSEA was also applied in conjunction with motif d ...
... sets that showed signi cant enrichment. About half the sets were shared between the two studies, and there were several non-identical sets that related to the same processes, such as up-regulation by telomerase, and two dierent insulin-related sets. GSEA was also applied in conjunction with motif d ...
Bookmarking Target Genes in Mitosis: A Shared
... rapidly reactivated postmitotically (e.g., GRP78 gene). Importantly, these authors find that trimethylation of lysine 4 at histone H3 (H3K4me3) is also maintained enriched at these promoters during mitosis, whereas other epigenetic markers of active chromatin are lost. Histone modifications play a key ...
... rapidly reactivated postmitotically (e.g., GRP78 gene). Importantly, these authors find that trimethylation of lysine 4 at histone H3 (H3K4me3) is also maintained enriched at these promoters during mitosis, whereas other epigenetic markers of active chromatin are lost. Histone modifications play a key ...
Monitoring transgenic animals
... Necessary actions concerning relevant treatments and humane endpoints to form a welfare profile for the line ...
... Necessary actions concerning relevant treatments and humane endpoints to form a welfare profile for the line ...
DNA Transcription All#read
... The terms "strong" and "weak" are often used to describe promoters and enhancers, according to their effects on transcription rates and thereby on gene expression. Alteration of promoter strength can have deleterious effects upon a cell, often resulting in disease. For example, some tumor-promoting ...
... The terms "strong" and "weak" are often used to describe promoters and enhancers, according to their effects on transcription rates and thereby on gene expression. Alteration of promoter strength can have deleterious effects upon a cell, often resulting in disease. For example, some tumor-promoting ...
Overview of Drosophila development
... A subset of five (out of 10-20) genes involved in segment polarity determination was selected for modelling. Interactions of these five genes were abstracted from the ...
... A subset of five (out of 10-20) genes involved in segment polarity determination was selected for modelling. Interactions of these five genes were abstracted from the ...
High Risk MDS and hypomethylating agents
... median 4 cycles of treatment needed for a response and subcutaneous use CALGB 9221, Phase III randomised control trial compared Azacytidine with Best supportive care ...
... median 4 cycles of treatment needed for a response and subcutaneous use CALGB 9221, Phase III randomised control trial compared Azacytidine with Best supportive care ...
Molecular pathology of growth anomalies in Montipora capitata
... growths of some coral species has lead to the use of the term “hyperplasia” in contrast to the earlier use of the word “neoplasia” 6. Hyperplasia is a prolifera?on in cells, which remain subject to ...
... growths of some coral species has lead to the use of the term “hyperplasia” in contrast to the earlier use of the word “neoplasia” 6. Hyperplasia is a prolifera?on in cells, which remain subject to ...