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Memory
Memory

... 8. Hwang D, Golby A, The brain bases of episodic memory: insights from fMRI intracranial eeg and patients with epilepsy, Epilepsy and behaviour, Vol 8, pp115126, 2006 9. Curtis C, Despozito M, Persistent activity in the prefrontal cortex during working memory, Vol 7, pp 415-423, Trends in Cognitive ...
Heredity and Genes
Heredity and Genes

... garden pea plant. Cross a heterozygous tall plant to a heterozygous tall plant. ...
The central premise of Nevo is that the adaptation of
The central premise of Nevo is that the adaptation of

... that conferred a clear-plaque morphology, and repressornegative mutants of the lac system. He was struck with the realization that zygotic induction of a k prophage led to the immediate expression of a series of phage genes, suggesting their control as a unit. In his autobiography, The Statue Within ...
File
File

... ladder. The sides of the ladder consist of long chains made up of “P”s and “S”s. Each “P” stands for a ________________ and each “S” stands for a ____________. 5. The actual DNA structure is not really like a ladder, but like two coils wrapped around each other. This structure is called a double ___ ...
Using DNA Subway in the Classroom Red Line Lesson
Using DNA Subway in the Classroom Red Line Lesson

... •DNA Subway is a suite of bioinformatics tools which have been placed in simplified workflows. • These tools allow students to work with the same data (DNA or Protein sequence data) used by biologists. • The DNA Subway can be used in the classroom to illustrate the basic principles of molecular bio ...
Comparative Genome Organization in plants: From Sequence and Markers to... and Chromosomes  Summary
Comparative Genome Organization in plants: From Sequence and Markers to... and Chromosomes Summary

... They can provide useful markers for chromosome identification, and their presence and distribution can provide evidence for evolutionary changes. Evidence does not exist for a constant mutation rate. Rather, bursts or evolutionary waves of mutations occurred. Tandem arrays are usual transcription si ...
Slide 1
Slide 1

... Common features to activation domains 1.They are often redundant; that is, a part of the activation domain can be deleted without loss of function. 2. They are modular and can activate transcription when paired with a variety of DNA-binding domains. 3. Activation domains can act synergistically: tw ...
Chromatin modification-aware network model - Bio
Chromatin modification-aware network model - Bio

... precise edge and nodes on the network. Chip-Chip, a tool for genome-scale mapping of in vivo protein–DNA interactions allows global views of transcription factor binding. Chip-Chip provides physical interaction data of two nodes. Chip-Chip data, which provides location data, is used as prior informa ...
My Slides - people.vcu.edu
My Slides - people.vcu.edu

... Aims - Discovery • Most gene regulatory roles unknown • A gene whose variants affect levels of a variety of other genes in a function regulates that process ...
MEDIAL TEMPORAL LOBE (THE LIMBIC SYSTEM)
MEDIAL TEMPORAL LOBE (THE LIMBIC SYSTEM)

... you have ever learned. All of your experiences and conscious memory fall into this category. It is analogous to the hard drive of a computer. Although no one knows exactly where this enormous database is stored, it is clear that the hippocampus is necessary to file away new memories as they occur. T ...
The Dawn of Artificial Gene Circuits
The Dawn of Artificial Gene Circuits

... generated * The attachment and hence (in steady state) the detachment rate for RNA polymerase (RNAP) ...
Determination and Differentiation
Determination and Differentiation

... b. Experiment#2- What genes are demethylated to cause a switch in cell fate? Remember if treat cells with azacytidine it can lead to demethylation of DNA. So in this experiment, fat cells were treated with azacytidine, so they no longer have a fat cell fate. Instead a fraction of them can now go the ...
SESSION TWO: - WOW! Locations
SESSION TWO: - WOW! Locations

... with learning theories and instructional design? ...
Genetics of Cancer
Genetics of Cancer

...  Cancers result from mutations in the genes that regulate cell growth.  DNA damage increases the risk of developing cancer.  Familial cancer syndromes are due to mutations in genes affecting DNA repair or genes that regulate cell growth. 1. What is an oncogene? 2. How do oncogenes arise and cause ...
Protein-coding genes
Protein-coding genes

... (ii) A ---> I, the amino group in in carbon 6 of adenine is replaced by a carbonyl group. I then acts as a G. Occurs in some ligandgated ion channels. (iii) U ---> C, in mRNA of the WT1 Wilms’ tumor gene (iv) U ---> A, in alpha-galactosidase mRNA ...
Molecular Genetics 2 - New York University
Molecular Genetics 2 - New York University

... • Each person’s genome is slightly different • Some differences alter biological function ...
Types of Memory
Types of Memory

... permanent changes in synaptic strength between assemblies of neurons. For example, rats raised in a rich environment have a thicker cortex with larger and more synapses. In the case of procedural memory, the changes are produced gradually by repeated exposure to the stimulus. ...
Document
Document

... She first analyzed many octads with regard to their requirement for pyridoxine. Out of 246 octads, two of them had an aberrant ratio in which two spores were pdx-1 and six were pdx-1+. These same spores were then analyzed with regard to the other two genes. In both cases, the aberrant asci gave a no ...
Lecture #8 Date
Lecture #8 Date

... copy per haploid set of chromosomes, multigene families exist as a collection of identical or very similar genes.  These likely evolved from a single ancestral gene.  The members of multigene families may be clustered or dispersed in the genome. ...


... [2] O. Troyanskaya, M. Cantor, G. Sherlock, P. Brown, T.Hastie, R. Tibshirani, D.Botstein and Russ B. Altman , “ Missing value estimation methods for DNA microarrays,” Bioinformatics, 2001, p.p 520–525. [3] A.Kaur, S.Bir, R.kamel,“Approximation of Missing Values in DNA Microarray Gene Expression Dat ...
Model organisms: the genes we share
Model organisms: the genes we share

... Based on your computer analysis of the HD gene in mice, what would happen if scientists mutated this gene the same way that the human gene is mutated in HD? Do you think the mice would develop HD? How could you determine if the mice are affected? ...
Gene Regulation - public.iastate.edu
Gene Regulation - public.iastate.edu

... Regulating Transcription lac operon: coordinated control ‹The genes for lactose metabolism are: » clustered together on the chromosome » controlled by a single promoter » transcribed as a single transcript ‹1 promoter + several coding regions (cistrons) ...
Lecture Note
Lecture Note

... 10010000 = 10200000 neurons are fired. Assuming 0.1% of these are fired (i.e. 1/1000 * 10000), the total number of neurons active in 0.1 sec is 10010 = 1020. The total number of neurons in the brain is 1011, so this suggests that the whole neural network in the brain be used (in multiple times). ...
Gene Regulation Powerpoint[1]
Gene Regulation Powerpoint[1]

... Gene Regulation • Operon - A series of genes that code for specific products and the regulatory elements that control these genes. – Structural genes –code for particular polypeptides – Promoter – site at which polymerases attach to start transcription – Operator –binding site for an inhibitory pro ...
Genetics - PCB 3063
Genetics - PCB 3063

... fused to other DNA-binding domains. – Alternatively, they can be recruited by protein-protein interactions - e.g., a DNA-binding protein binds the enhancer, and it contains a region that recruits and acid-blob protein. ...
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Epigenetics in learning and memory

While the cellular and molecular mechanisms of learning and memory have long been a central focus of neuroscience, it is only in recent years that attention has turned to the epigenetic mechanisms behind the dynamic changes in gene transcription responsible for memory formation and maintenance. Epigenetic gene regulation often involves the physical marking (chemical modification) of DNA or associated proteins to cause or allow long-lasting changes in gene activity. Epigenetic mechanisms such as DNA methylation and histone modifications (methylation, acetylation, and deacetylation) have been shown to play an important role in learning and memory.
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