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TOC  - Genes | Genomes | Genetics
TOC - Genes | Genomes | Genetics

... signaling pathway promoting the proliferative fate. Here the authors demonstrate that a Pumilio homologue, PUF-8, helps to maintain the balance between the proliferative fate and meiotic entry of this stem cell population by inhibiting the proliferative fate. Loss of puf-8 activity enhances the over ...
Reporter constructs are a tool for studying gene regulation
Reporter constructs are a tool for studying gene regulation

... Protein modifications after translation provide a final level of control over gene function ...
Gene Section chromosomal) isoform I and Y) Atlas of Genetics and Cytogenetics
Gene Section chromosomal) isoform I and Y) Atlas of Genetics and Cytogenetics

... supercoils; HMGIY was shown to be an essential component of enhanceosome (higher order transcription enhancer complex); positive induction of several genes including IFN-b, E-selectin, interleukin-2 receptor a-chain, the chemokine MGSA/GRO, and the class II major histocompatibility complex gene HLAD ...
Supplementary Figure S5 (ppt 562K)
Supplementary Figure S5 (ppt 562K)

... ...
The Little Things About the Little Things Inside of Us The Eukaryotic
The Little Things About the Little Things Inside of Us The Eukaryotic

... In the disease beta thalassemia, a mutation occurs at the consensus sequence in the βglobin gene—the pre-mRNA can not be spliced correctly. Non-functional β-globin mRNA is produced. Mature mRNA leaves the nucleus through nuclear pores. TAP protein binds to the 5’ end, TAP binds to other proteins tha ...
Molecular Cell Biology Prof. D. Karunagaran Department of
Molecular Cell Biology Prof. D. Karunagaran Department of

... For example, more than one-fifth of the amino acids in each of the core histones are either lysine or arginine (two amino acids with basic side chains), and their positive charges can effectively neutralize the negatively charged DNA backbone. ...
No Slide Title
No Slide Title

... ...Small volatile chemical signals, – function in communication between animals, – act much like hormones in influencing physiology and development. ...
16. Nuclear gene organization
16. Nuclear gene organization

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Wagner for the Womb
Wagner for the Womb

... Similar studies in different animal models have been replicated to correlate prenatal music stimulation with enhancement of spatial learning. In another study, music or no stimulation was provided to fertilized chick eggs. Following hatching, the chicks were trained to perform a similar maze task to ...
BB30055: Genes and genomes
BB30055: Genes and genomes

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Regulation of Gene Expression in Eukaryotes
Regulation of Gene Expression in Eukaryotes

... Northern blot could be done, in which RNA from each tissue patch is fractionated by gel electrophoresis, then probed with radioactively labeled white-gene DNA. Presence of a radioactive band would indicate mRNA from the white gene, and would be expected in the red tissue. Lack of a radioactive band ...
Slide 1
Slide 1

... However, some will be beneficial, and the cell with the new genetic information resulting from the mutation will be able to outperform other cells. This enhanced fitness at the cellular level may increase the survival and reproductive performance of the organism, and in that case the mutation will b ...
Zoo/Bot 3333
Zoo/Bot 3333

... dominant disease of late onset (approximately 40 years of age). A genomic DNA sample from each family member is digested with the restriction enzyme Taq1, run on an electrophoretic gel, and subjected to Southern blot analysis. The probe used in this instance is a DNA fragment linked to the disease g ...
Epigenetics and Inheritance
Epigenetics and Inheritance

... chemicals that relay signals in the nervous system (neurotransmitters). Mouse knockouts of the DNMT1 gene are lethal at 8.5 days in the embryo. In humans, a mutation in the DNMT1 gene is named hereditary sensory and autonomic neuropathy type IE (HSAN IE) and is characterized by a gradual loss of int ...
Assay for Methylation of genes
Assay for Methylation of genes

... MSI is caused by defects in DNA mismatch repair enzymes encoded by the genes MLH1, MSH2, MSH3, PMS1, PMS2, MLH3, and MSH6. These enzymes normally proof-read and correct nucleotide base-pair mistakes made during DNA replication. Impaired DNA mismatch repair activity leads to the accumulation of muta ...
Albinism Advanced - xy-zoo
Albinism Advanced - xy-zoo

... light-colored hair. Melanin is an extremely important molecule in humans for many reasons, one being its ability to protect the DNA in the cell’s nucleus from damage by UV light from the sun. This is one reason the skin darkens after being exposed to sunlight and people living closer to the equator ...
Gene Section BCL11B (B-cell lymphoma/leukaemia 11B) Atlas of Genetics and Cytogenetics
Gene Section BCL11B (B-cell lymphoma/leukaemia 11B) Atlas of Genetics and Cytogenetics

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RT-PCR lab
RT-PCR lab

... on (by “on,” we mean active and producing mRNA?)? If a certain gene is on when the cell divides, the gene might produce a protein that causes cell division…. ...
The Making of the Fittest - 5 Short Films Watch any 4 of the 5 short
The Making of the Fittest - 5 Short Films Watch any 4 of the 5 short

... the Pitx1 gene. To determine what the Pitx1 gene did, these scientists intentionally mutated the Pitx1 protein-coding region in mice so that the Pitx1 protein was no longer produced. These mice died before birth and had miniaturized hind limbs. a. What do you think these scientists concluded about t ...
Gene Section CBP (CREB-binding protein) Atlas of Genetics and Cytogenetics
Gene Section CBP (CREB-binding protein) Atlas of Genetics and Cytogenetics

... of a CREB-Binding domain, a bromodomain. Cystidine/Histidine-rich domains, and Glutamine-rich domains in COOH-term. ...
GENETICS 310
GENETICS 310

... IV.    Below  are  7  family  pedigrees  labeled  A  to  G  where  individuals  with  a  genetic  trait  are   filled  in  squares  or  circles.    List  the  pedigrees  could  potentially  result  from  a  trait  inherited   throu ...
Leukaemia Section t(11;22)(q23;q13) Atlas of Genetics and Cytogenetics in Oncology and Haematology
Leukaemia Section t(11;22)(q23;q13) Atlas of Genetics and Cytogenetics in Oncology and Haematology

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Genetics and Strong Heart Study
Genetics and Strong Heart Study

... • There are a series of church fires in Ohio. Why? • Could they all be accidents? – All are heated with natural gas – There seem to be twice as many church fires as there are in other buildings heated with ...
Slide 1
Slide 1

... would lead to a male phenotype? a. XX b.XY c. XXY d.XO e. XYY ...
< 1 ... 129 130 131 132 133 134 135 136 137 ... 172 >

Epigenetics in learning and memory

While the cellular and molecular mechanisms of learning and memory have long been a central focus of neuroscience, it is only in recent years that attention has turned to the epigenetic mechanisms behind the dynamic changes in gene transcription responsible for memory formation and maintenance. Epigenetic gene regulation often involves the physical marking (chemical modification) of DNA or associated proteins to cause or allow long-lasting changes in gene activity. Epigenetic mechanisms such as DNA methylation and histone modifications (methylation, acetylation, and deacetylation) have been shown to play an important role in learning and memory.
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