Inferring Cellular Networks Using Probabilistic Graphical Models
... • We associated each gene with the processes in which it participates. Resulted in 923 GO categories, 208 MIPS categories, and 87 KEGG pathways. For each module and for each annotation, we calculated the fration of genes in the module associated with that annotaiton and used the hypergeometric distr ...
... • We associated each gene with the processes in which it participates. Resulted in 923 GO categories, 208 MIPS categories, and 87 KEGG pathways. For each module and for each annotation, we calculated the fration of genes in the module associated with that annotaiton and used the hypergeometric distr ...
Epigenetic memory in mammals
... methylated differently between parental alleles and some, which are derived from sperm and oocytes, behave as ICRs (Morgan et al., 2005). Genomic imprints are maintained through cis- and transacting DNA-binding factors that specifically recognize ICRs and prevent active demethylation on the paternall ...
... methylated differently between parental alleles and some, which are derived from sperm and oocytes, behave as ICRs (Morgan et al., 2005). Genomic imprints are maintained through cis- and transacting DNA-binding factors that specifically recognize ICRs and prevent active demethylation on the paternall ...
Document
... and inhibit forgetting when silenced (Berry et al., 2014). To better understand how these DAN forgetting neurons are modulated by the fly’s experience, the authors first simultaneously monitored the fly’s locomotion on an air-suspended ball and DAN calcium activity using a genetically encoded calciu ...
... and inhibit forgetting when silenced (Berry et al., 2014). To better understand how these DAN forgetting neurons are modulated by the fly’s experience, the authors first simultaneously monitored the fly’s locomotion on an air-suspended ball and DAN calcium activity using a genetically encoded calciu ...
Chapter 18 Gene Regulation
... The Roles of Transcription Factors • To initiate transcription, eukaryotic RNA polymerase requires the assistance of proteins called transcription factors • General transcription factors are essential for the transcription of all protein-coding genes • In eukaryotes, high levels of transcription of ...
... The Roles of Transcription Factors • To initiate transcription, eukaryotic RNA polymerase requires the assistance of proteins called transcription factors • General transcription factors are essential for the transcription of all protein-coding genes • In eukaryotes, high levels of transcription of ...
More on microarrays. (2/17)
... – Goal: Characterize effect(s) of drug X three hours after it is introduced into normal adult mice by the expression level of liver cell genes. – Approach: Gene expression profiles of normal adult mice liver cells that are not treated with drug X are used as the control state. • Call the preinterven ...
... – Goal: Characterize effect(s) of drug X three hours after it is introduced into normal adult mice by the expression level of liver cell genes. – Approach: Gene expression profiles of normal adult mice liver cells that are not treated with drug X are used as the control state. • Call the preinterven ...
Douillard found that Flik
... • Under the control of the RpoN there is an increase in transcription of genes ...
... • Under the control of the RpoN there is an increase in transcription of genes ...
熊本大学学術リポジトリ Kumamoto University Repository System
... expression and its potential involvement in gastrulation processes. In the mouse, goosecoid is expressed in the developing primitive streak, more specifically in those cells that are undergoing anterior migration – one of the earliest features of gastrulation. The fate of these cells has been demons ...
... expression and its potential involvement in gastrulation processes. In the mouse, goosecoid is expressed in the developing primitive streak, more specifically in those cells that are undergoing anterior migration – one of the earliest features of gastrulation. The fate of these cells has been demons ...
Biotechnology - Biology Junction
... if you are going to engineer DNA & genes & organisms, then you need a set of tools to work with this unit is a survey of those tools… ...
... if you are going to engineer DNA & genes & organisms, then you need a set of tools to work with this unit is a survey of those tools… ...
Binary Ti vector plasmids
... responsive gene fused to GUS, show expression in the stomata when exposed to drought or induced by ABA ...
... responsive gene fused to GUS, show expression in the stomata when exposed to drought or induced by ABA ...
Supplementary materials
... Once the data normalization step has been accomplished, statistically relevant comparisons can be made between arrays within an experimental data set. In experiments where there are no true pair wise comparisons, such as a developmental or time course linked series, normalizing all arrays against a ...
... Once the data normalization step has been accomplished, statistically relevant comparisons can be made between arrays within an experimental data set. In experiments where there are no true pair wise comparisons, such as a developmental or time course linked series, normalizing all arrays against a ...
Mining Phenotypes and Informative Genes Underlying
... Recently introduced DNA microarray technology permits rapid, largescale screening for patterns of gene expression and gives simultaneous, semi-quantitative readouts on the level of expression of thousands of genes for samples. The raw microarray data (images) can then be transformed into gene expres ...
... Recently introduced DNA microarray technology permits rapid, largescale screening for patterns of gene expression and gives simultaneous, semi-quantitative readouts on the level of expression of thousands of genes for samples. The raw microarray data (images) can then be transformed into gene expres ...
Genome demethylation and imprinting in the endosperm
... that regions require demethylation in the central cell for proper endosperm imprinting and development after fertilization. Because the DNA demethylation is not targeted to imprinted genes, but is genome wide, it could result in widespread TE reactivation. TEs, if reactivated, have the ability to ca ...
... that regions require demethylation in the central cell for proper endosperm imprinting and development after fertilization. Because the DNA demethylation is not targeted to imprinted genes, but is genome wide, it could result in widespread TE reactivation. TEs, if reactivated, have the ability to ca ...
Common types of DNA damage Different types of repair fix different
... Different types of repair fix different types of damage In increasing order of complexity of the problem: • direct repair of specific modification • base excision repair: missing or altered base • (oligo)nucleotide excision repair: distortion of B-DNA with damage on one strand • mismatch repair: bot ...
... Different types of repair fix different types of damage In increasing order of complexity of the problem: • direct repair of specific modification • base excision repair: missing or altered base • (oligo)nucleotide excision repair: distortion of B-DNA with damage on one strand • mismatch repair: bot ...
Supplementary Figure 1. Generation of IDH2 mutant mice. (A
... Supplementary Figure 4. Reduced lipogenesis and stimulation of thermogenesis in adipose tissues of IDH2-deficient mice on a normal diet. (A) Quantifications of lipogenesis signal in sections of visceral WAT from wild-type and IDH2-/- mice. Quantifications of the levels of p53 and lipogenic protein ...
... Supplementary Figure 4. Reduced lipogenesis and stimulation of thermogenesis in adipose tissues of IDH2-deficient mice on a normal diet. (A) Quantifications of lipogenesis signal in sections of visceral WAT from wild-type and IDH2-/- mice. Quantifications of the levels of p53 and lipogenic protein ...
Robust systems persist in response to mutations
... one binding site. Payne and Wagner found that the more sites a transcription factor can bind to—and the more one can "hop" from one compatible site to the next through single mutations—the more robust the transcription factor's function. What's more, that robustness makes it easier for a population ...
... one binding site. Payne and Wagner found that the more sites a transcription factor can bind to—and the more one can "hop" from one compatible site to the next through single mutations—the more robust the transcription factor's function. What's more, that robustness makes it easier for a population ...
(a) p 1 - Biology Department | UNC Chapel Hill
... • Becoming more common • Most species only partially characterized • Usefulness also compromised by sparse synteny ...
... • Becoming more common • Most species only partially characterized • Usefulness also compromised by sparse synteny ...
The chromo domain protein Chd1p from budding yeast is an ATP
... example, the human genome includes CHD1, CHD2, CHD3 and CHD4 (Woodage et al., 1997). The human CHD3 and CHD4 proteins have recently been shown to co-purify with each other and with the human histone deacetylase complex (HDAC) (Tong et al., 1998; Xue et al., 1998; Zhang et al., 1998). A Xenopus CHD p ...
... example, the human genome includes CHD1, CHD2, CHD3 and CHD4 (Woodage et al., 1997). The human CHD3 and CHD4 proteins have recently been shown to co-purify with each other and with the human histone deacetylase complex (HDAC) (Tong et al., 1998; Xue et al., 1998; Zhang et al., 1998). A Xenopus CHD p ...
Title Screening candidate genes required for CENP
... segregation of sister chromatids and hence faithful transmission of genetic information to daughter cells. Being an epigenetic marker of functional centromere, a histone H3 variant CENP-AHCP-3 forms the structural foundation of kinetochore. Without CENP-AHCP-3, kinetochore proteins cannot build on c ...
... segregation of sister chromatids and hence faithful transmission of genetic information to daughter cells. Being an epigenetic marker of functional centromere, a histone H3 variant CENP-AHCP-3 forms the structural foundation of kinetochore. Without CENP-AHCP-3, kinetochore proteins cannot build on c ...
Mixed questions
... 17. Gene expression can be regulated at several levels. Explain. 18. Gene expression can be regulated at the levels of transcription and translation. Discuss each with respect to energy efficiency of each mechanism. 19. Define the following terms: (a) operon (b) promoter (c) regulator (d) inducer (e ...
... 17. Gene expression can be regulated at several levels. Explain. 18. Gene expression can be regulated at the levels of transcription and translation. Discuss each with respect to energy efficiency of each mechanism. 19. Define the following terms: (a) operon (b) promoter (c) regulator (d) inducer (e ...
Topic # 7: Nucleic Acids
... A. Regulation of gene expression by proteins 1. Gene expression is regulated by proteins that bind to specific base sequences in DNA 2. Some proteins are always necessary for the survival of an organism 3. These are expressed in an unregulated fashion 4. Other proteins need to be produced at certain ...
... A. Regulation of gene expression by proteins 1. Gene expression is regulated by proteins that bind to specific base sequences in DNA 2. Some proteins are always necessary for the survival of an organism 3. These are expressed in an unregulated fashion 4. Other proteins need to be produced at certain ...
Nucleic Acids and Chromatin
... - Understand how chromosomal structure and chromatin structure affect gene expression. Understand how modification of chromatin structure can lead to epigenetic inheritance. Supplementary materials: These can be found on the Molecular basis of Medicine web site, I. Nucleic acid structure A. Chemical ...
... - Understand how chromosomal structure and chromatin structure affect gene expression. Understand how modification of chromatin structure can lead to epigenetic inheritance. Supplementary materials: These can be found on the Molecular basis of Medicine web site, I. Nucleic acid structure A. Chemical ...